• 공업화학
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• 제9권4호
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• pp.603-607
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• 1998

Cellulose를 출발물질로 하여 ethylene oxide와 hydroxyethylcellulose를 합성하였다. Epichlorohydrin과 triakylamine을 치환반응시켜 제4급 암모늄염을 만든후, 산을 첨가하여 3-chloro-2-hydroxypropyltrialkylammonium chloride를 얻었다. Hydroxyethylcellulose와 glycidylalkylammonium chloride 또는 3-chloro-2-hydroxypropyltrialkylammonium chloride를 coupling하여 지금까지 알려져 있지 않은 화합물 hydroxyethylcellulose-2-hydroxypropylammonium chloride ether와 hydroxyethyl-cellulose-2-hydroxypropyltriethylammonium chloride ether를 각각 73.9%, 74.2%의 수율로 합성하였다.

• Natural Product Sciences
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• 제19권2호
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• pp.179-185
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• 2013

Polygalae radix (PR) has traditionally been used as a sedative and anti-stress agent in oriental countries for a long time. PR which contains many ingredients is especially rich in saponins. This study was performed to investigate whether ethanol extract of PR enhances pentobarbital-induced sleep behaviors. In addition, possible mechanisms also were investigated. PR inhibited locomotor activity in mice. PR increased sleep rate and sleep time by concomitant administration with sub-hypnotic dose of pentobarbital (28 mg/kg). PR prolonged total sleeping time, and shortened sleep latency induced by pentobarbital (42 mg/kg). In addition, PR increased intracellular chloride concentration in primary cultured neuronal cells. The expression level of glutamic acid decarboxylase (GAD) were increased, and ${\gamma}$-aminobutyric acid $(GABA)_A$ receptors subunits were modulated by PR, especially increasing ${\gamma}$-subunit expression. In conclusion, PR augments penobarbital-induced sleep behaviors through activation of $GABA_A$ receptors and chloride channel complex.

• Bulletin of the Korean Chemical Society
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• 제21권9호
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• pp.860-866
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• 2000

Hydrocarbostyril, which is a key intermediate in our new synthetic route to 6-nitroquipazine, can be prepared from 1-indanone oxime by Beckmann rearrangement. We have optimized the reaction by using a Lewis acid, aluminum chloride,in the yield of 91% instead of common acids such as polyphosphoric acid,and sulfuric acid used in conventional Beckmann rearrangement (20% in the literature, 10% in our experiment).The optimized condition is established by usingthree equivalents of aluminum chloride in CH2Cl2 at -40 $^{\circ}C$ - room tempera-turefor 40 min. We have applied this condition to other 1-indanone derivatives, such as 4-methyl-, 4-methoxy-, 4-nitro and 6-nitro-1-indanones. The mechanism ofthis BR has been proposed on the basis of the effect of tem-perature and substituenton product ratio, with the aid of PM3 calculation for a model system.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2003년도 봄 학술발표회 논문집
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• pp.417-421
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• 2003

The purpose of this paper is to study on the construction of roadbed with environmental friendly soil amendment agent. The special amendment agent used in this study is mainly composed of inorganic metal salts such as sodium chloride, magnesium chloride, potassium chloride, calcium chloride,, thus is friendly to the environment, and has a function of soil-cement-agent solidification. Various components of this agent weaken the negative function of humic acid and decompose humic acid itself. Then, the calcium cation of the cement can now be made contact directly to the soil surface. The project of local road demonstration of roadbed construction with special soil treatment agent was peformed in Northeast Thailand on August 1999 by the sponsor of Highway Department of Thailand. A series of field experiments including unconfined compressive strength were carried out to investigate the physical and mechanical characteristics of solidified roadbed treated by this solidifying agent. The results of this research showed that the roadbed using poor soil could be efficiently constructed by treatment of this amendment agent.

• 폴리머
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• 제39권1호
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• pp.1-5
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• 2015

The effects of zeolite on the thermal stability of poly(vinyl chloride) (PVC) were investigated by the static thermal stability test, pyrolysis experiment and ultraviolet spectrum. The results showed that the porous zeolite could absorb hydrogen chloride (HCl), which suppressed the catalysis of HCl on thermal degradation of PVC, thus improved the thermal stability of PVC. The oxidizing acid which was loaded on zeolite had oxidated on the double bond that formed during the dehydrochlorination of PVC. This process could prohibit the growth of the conjugated polyene and improved the color of PVC. Hence, zeolite might be possible to come up with a high performance thermal stabilizer.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2004년도 학술대회지
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• pp.71-76
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• 2004

This paper investigate that the effect of the concrete containing mineral admixtures(pozzolanic materials such as fly-ash, ground granulated blast-furnace slag, silica fume and meta kaolin) on the resistance properties to chloride ion invasion. The purposed testing procedure was applied to the concrete added mineral admixtures for $3\sim4$ replacement ratios under W/B ratios ranged from 0.40 to 0.55. Specimens were immersed in $3.6\%$ NaCl solution for 330 days, and penetration depth, water soluble chloride contents and acid soluble chloride contents were measured in 28, 91, 182 and 330 days. Then, diffusion coefficient were calculated using total chloride contents. As a results. the kinds of mineral admixture and replacement ratios had a great effect on the resistance property of the concrete to chloride ion invasion compared with the plain concrete. And the optimal replacement ratios of mineral admixture had a limitation for each admixtures. The amount of acid soluble chloride ions and water soluble chloride ions were varied with the kinds of mineral admixtures and the penetration depth from the concrete skin. Chloride diffusion coefficient of each concretes decreased with the time elapsed. and the diffusion coefficients of the concrete immersed salt water for 330 days had a establishment with the compressive strength measured before immersing.

• 약학회지
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• 제3권1호
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• pp.23-25
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• 1957

The herb of Geranium sibirium L, a drug knwon as "Chui Sonni Poul" distributed widely, has been used as a folk-medicine for the treatment of diarrhea. The dried entire herb is boiled with methanol and methanol is distilled of from the filtered methanol extract under reduced pressure. Then the extract is boiled with water and filtered off. From the filtrate, the following substances are isolated and identified by treating with organic solvents as ether, ethyl acetate, and etc.: 1. Gallic acid: a colorless needle crystal which is soluble in alcohol and water. mp.235.deg. C, positive (dark blue) against the ferric chloride reagent. 0.76 percent of gallic acid is yielded from the herb. 2. Quercetin: a light yellow crystal. mp.194.deg. C. negative against the ferric chloride reagent. 3. Ellagic acid: a light yellow crystal which is insoluble in ehter and acetone and slightly soluble in alcohol. Positive (blue) against the ferric chloride reagent. The crystal obtained by recrystalisation from pyridine, does not melt by 360.deg. C. Represent a yield of 0.03 percent from the herb. 4. Crude tannin: a approximately 7.6 percent of crude tannin is yielded by treating with ethyl acetate. gallic acid and querceetin are yielded by hydrosis with dliute sulfuric acid. Based on the above results, the following suggestion could be recommendable; Geraed in the Japanese Pharmacoeia VI.acoeia VI.

• 한국식품과학회지
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• 제11권2호
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• pp.93-98
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• 1979

본실험(本實驗)에서는 Maillard형(型) 갈색화반응(褐色化反應)의 중요(重要)한 중간생성체(中間生成體)의 하나인 pyrazine유도체(誘導體)의 항산화효과(抗酸化效果)를 보기위해 먼저 이를 주요구성성분(主要構成成分)으로 하는 methylene chloride추출물(抽出物)의 항산화효과(抗酸化效果)를 검토(檢討)하고저 했다. 즉, pyrazine유동체생성(誘導體生成)의 최적조건(最適條件)에 따라 glucose-ammonia(1M+8M)갈색화(褐色化) 반응액(反應液)을 $100^{\circ}C$에서 4시간(時間) 반응(反應)시킨후, 여기서 methylene chloride추출물(抽出物)을 얻었다. 이 추출물(抽出物)과 별도(別途)로 furfural을 식용(食用)평지씨기름기질(基質)에 첨가(添加)하여, control과 함께 $37^{\circ}C{\pm}1.0^{\circ}C$에서 저장(貯藏)하여, 그 과산화물가(過酸化物價)(POV), thiobarbituric acid value(TBA 가(價))와 산가(酸價)(AV)를 규칙적으로 측정(測定)하였다. 그리고 methylene chloride추출물(抽出物)과 furfural이 들은 기질(基質)들의 POV, TBA가(價)와 AV의 변화(變化)를 control의 그것과 비교(比較)하여 methylene chloride추출물(抽出物)과 furfural의 항산화효과(抗酸化效果)를 검토(檢討)하였다. 이상(以上)의 실험(實驗)의 결과(結果), glucose-ammonia (1M+8M)갈색화반응액(褐色化反應液)의 methylene chloride추출물(抽出物)에는 상당(相當)한 항산화효과(抗酸化效果)를, 그리고 furfural에도 다소의 항산화효과(抗酸化效果)를 확인(確認)할 수 있었다.

• Bulletin of the Korean Chemical Society
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• 제23권4호
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• pp.539-540
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• 2002

• Journal of Periodontal and Implant Science
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• 제29권2호
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• pp.325-333
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• 1999

The antibacterial efficacy of a mouthrinse(Denta Gargle) containing CPC(cetylpyridinium chloride), NaF and UDCA(ursodeoxycholic acid), on major periodontopathogens, was in vitro examined and compared with that of Listerine by a broth dilution method. The bacteria tested were Actinobacillus actinomycetemcomitans, Bacteroides forsythus, Fusobacterium nucleatum subsp. vincentii, Prevotella intermedia, Porphyromonas gingivalis and Treponema denticola. The growth of all the bacteria were completely inhibited by a 1-min exposure to the both mouthrinses. When diluted at 1:5 or more, all bacteria analyzed but P. intermedia were not inhibited by Listerine. In contrast, Denta Gargle showed highly increased maximum inhibitory dilutions(MID) against all periodontopathogens included in this study, with MIDs ranging from 5-fold(F. nucleatum) to 160-fold dilutions(P. intermedia). The MIDs against A. actinomycetemcomitans, B. forsythus, P. gingivalis and T. denticola. were 1:40, 1:80, 1:80 and 1:80, respectively.