• Title/Summary/Keyword: absorption loss

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Effect of fermented sarco oyster extract on age induced sarcopenia muscle repair by modulating regulatory T cells

  • Kyung-A Byun;Seyeon Oh;Sosorburam Batsukh;Kyoung-Min Rheu;Bae-Jin Lee;Kuk Hui Son;Kyunghee Byun
    • Fisheries and Aquatic Sciences
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    • v.26 no.6
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    • pp.406-422
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    • 2023
  • Sarcopenia is an age-related, progressive skeletal muscle disorder involving the loss of muscle mass and strength. Previous studies have shown that γ-aminobutyric acid (GABA) from fermented oysters aids in regulatory T cells (Tregs) cell expansion and function by enhancing autophagy, and concomitantly mediate muscle regeneration by modulating muscle inflammation and satellite cell function. The fermentation process of oysters not only increases the GABA content but also enhances the content of branched amino acids and free amino acids that aid the level of protein absorption and muscle strength, mass, and repair. In this study, the effect of GABA-enriched fermented sarco oyster extract (FSO) on reduced muscle mass and functions via Treg modulation and enhanced autophagy in aged mice was investigated. Results showed that FSO enhanced the expression of autophagy markers (autophagy-related gene 5 [ATG5] and GABA receptor-associated protein [GABARAP]), forkhead box protein 3 (FoxP3) expression, and levels of anti-inflammatory cytokines (interleukin [IL]-10 and transforming growth factor [TGF]-β) secreted by Tregs while reducing pro-inflammatory cytokine levels (IL-17A and interferon [IFN]-γ). Furthermore, FSO increased the expression of IL-33 and its receptor IL-1 receptor-like 1 (ST2); well-known signaling pathways that increase amphiregulin (Areg) secretion and expression of myogenesis markers (myogenic factor 5, myoblast determination protein 1, and myogenin). Muscle mass and function were also enhanced via FSO. Overall, the current study suggests that FSO increased autophagy, which enhanced Treg accumulation and function, decreased muscle inflammation, and increased satellite cell function for muscle regeneration and therefore could decrease the loss of muscle mass and function with aging.

Ecophysiological characteristics of Rosa rugosa under different environmental factors

  • Young-Been Kim;Sung-Hwan Yim;Young-Seok Sim;Yeon-Sik Choo
    • Journal of Ecology and Environment
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    • v.47 no.3
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    • pp.85-102
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    • 2023
  • Background: Ecophysiological characteristics of Rosa rugosa were analyzed under different environmental factors from May to October 2022. Photosynthesis, chlorophyll fluorescence, chlorophyll content, leaf water content (LWC), osmolality, carbohydrate content, and total ion content were measured to compare the physiological characteristics of R. rugosa at two study sites (i.e., in large pots and in the Goraebul coastal sand dune area). Results: When R. rugosa was exposed to high temperatures, photosynthetic parameters including net photosynthetic rate (PN) and stomatal conductance (gs) in both experiment areas declined. In addition, severe photoinhibition occurs when R. rugosa is continuously exposed to high photosynthetically active radiation (PAR), and because of this, relatively low Y(II) (i.e., the quantum yield of photochemical energy conversion in photosystem II [PSII]) and high Y(NO) (i.e., the quantum yield of non-regulated, non-photochemical energy loss in PSII) in the R. rugosa of the pot were observed. As the high Y(NPQ) (i.e., the quantum yield of regulated non-photochemical energy loss in PSII) of R. rugosa in the coastal sand dune, they dissipated the excessed photon energy through the non-photochemical quenching (NPQ) mechanism when they were exposed to relatively low PAR and low temperature. Rosa rugosa in the coastal sand dune has higher chlorophyll a and carotenoid content. The high chlorophyll a + b and low chlorophyll a/b ratios seemed to optimize light absorption in response to low PAR. High carotenoid content played an important role in NPQ. As a part of the osmotic regulation in response to low LWCs, R. rugosa exposed to high temperatures and continuously high PAR used soluble carbohydrates and ions to maintain high osmolality. Conclusions: We found that Fv/Fm was lower in the potted plants than in the coastal sand dune plants, indicating the vulnerability of R. rugosa to high temperatures and PAR levels. We expect that the suitable habitat range for R. rugosa will shrink and move to north under climate change conditions.

Optimization of Packaging Design of TWEAM Module for Digital and Analog Applications

  • Choi, Kwang-Seong;Lee, Jong-Hyun;Lim, Ji-Youn;Kang, Young-Shik;Chung, Yong-Duck;Moon, Jong-Tae;Kim, Je-Ha
    • ETRI Journal
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    • v.26 no.6
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    • pp.589-596
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    • 2004
  • Packaging technologies for a broadband and narrowband modulator with a traveling wave electro-absorption modulator (TWEAM) device were developed. In developing a broadband modulator, the effects of the device and packaging designs on the broadband performance were investigated. The optimized designs were obtained through a simulation with the result that we developed a broadband modulator with a 3 dB bandwidth of 38 GHz in the electrical-to-optical (E/O) response, an electrical return loss of less than -10 dB at up to 26 GHz, an rms jitter of 1.832 ps, and an extinction ratio of 5.38 dB in a 40 Gbps non-return to zero (NRZ) eye diagram. For analog application, the effect of the RF termination scheme on the fractional bandwidth was studied. The microstrip line with a double stub as a matching circuit and a laser trimming process were used to obtain an $S_{11}$ of -34.58 dB at 40 GHz and 2.9 GHz bandwidth of less than -15 dB.

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Effect of variable degrees of jejunal resection upon different clinico-biochemical parameters in dogs

  • Dilawer, Muhammad Sohail;Khan, Muhammad Arif;Abidin, Zain ul;Azeem, Shahan;Majeed, Khalid Abdul;Shahbaz, Adeel;Khan, Aamir Riaz
    • Korean Journal of Veterinary Research
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    • v.51 no.4
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    • pp.309-313
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    • 2011
  • Dogs are considered to be the best companions of human beings due to their loyalty, obedience and pleasant disposition. Jejunum is the largest part of small intestine mainly involved in absorption of nutrients. Jejunal resection up to 80% allows normal weight gain while resection up to 90% increased morbidity and mortality. In the present study, 20 dogs were divided into 4 groups based on the degree of jejunal resection i.e. A (70% resection), B (80% resection) and C (100% resection) while group D served as control. Dogs in the 70% and 80% jejunal resection group showed normal growth and function while 100% jejunal resection resulted in weight loss and alteration of hematological and biochemical parameters.

Growth Performance, Carcass Characteristics and Meat Yield of Boer Goats Fed Diets Containing Leaves or Whole Parts of Andrographis paniculata

  • Yusuf, A.L.;Goh, Y.M.;Samsudin, A.A.;Alimon, A.R.;Sazili, A.Q.
    • Asian-Australasian Journal of Animal Sciences
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    • v.27 no.4
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    • pp.503-510
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    • 2014
  • The study was conducted to determine the effect of feeding diets containing Andrographis paniculata leaves (APL), whole Andrographis paniculata plant (APWP) and a control without Andrographis paniculata (AP0), on growth performance, carcass characteristics and meat yield of 24 intact Boer bucks. The results obtained indicated that inclusion of Andrographis paniculata significantly improved feed intake, weight gain, feed efficiency and live weight. The ratios of carcass to fat, lean to bone, lean to fat, and composition of meat were also improved. In addition, there were significant differences (p<0.05) between the dietary treatments in dressing percentage and chilling loss. Goats fed on AP0 (control) had significantly higher proportions of fat and bone, as well as thicker back fat than the supplemented animals (APL and APWP). Higher gut fill in animals fed Andrographis paniculata suggested slow rate of digestion, which could have improved utilization and absorption of nutrients by the animals. Goats fed Andrographis paniculata also produced higher meat yield and relatively lower fat contents (p<0.05).

Design of 850 nm Vertical-Cavity Surface-Emitting Lasers by Using a Transfer Matrix Method (전달 행렬 방법을 이용한 850 nm수직 공진기 레이저 구조의 최적설계)

  • Kim Tae-Yong;Kim Sang-Bae
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.41 no.1
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    • pp.35-46
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    • 2004
  • In comparison with edge-emitting lasers(EELs), predicting the output power and slope efficiency of Vertical-Cavity Surface-Emitting Lasers(VCSELs) is very difficult due to the absorption loss in DBR layers. However, by using transfer matrix method(TMM), we've made possible to calculate such parameters of multi-layer structures like VCSELs. In this paper, we've calculated the threshold gain, threshold current and slope efficiency through the methodology based on TMM. Also TMM is the way of customizing the VCSEL structure for the desired threshold current and slope efficiency by changing the number of DBR mirror layers.

Salt Farm Parallel Solar Power System:Field tests and Simulations (염전 병행 태양광 발전의 실증과 시뮬레이션)

  • Park, Jongsung;Kim, Bongsuck;Gim, Geonho;Lee, Seungmin;Lim, Cheolhyun
    • Current Photovoltaic Research
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    • v.7 no.4
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    • pp.121-124
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    • 2019
  • In this research, the concept of a salt farm parallel solar power system, which produce salt and electricity at the same site, is proposed for the first time in the world. The concept is that large waterproof plates made by interconnected solar modules are installed at the bottom of the salt farm. The pilot system was successfully installed at a sea shore, and verified its feasibility as a solar power plant. For deeper understanding, simulations for power prediction of the system were carried out and compared with the field test results. The power generation of the salt farm parallel system is comparable to conventional solar power plants. The cooling effect by sea water contributes more to the increase in the crystalline silicon photovoltaic module performance than the absorption loss due to sea water by maintaining certain height above the module.

Photovoltaic Properties of Tandem Structure Consisting of Quantum Dot Solar cell and Small Molecule Organic Solar cell

  • Jang, Jinwoong;Choi, Geunpyo;Yim, Sanggyu
    • Proceedings of the Korean Vacuum Society Conference
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    • 2015.08a
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    • pp.249.2-249.2
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    • 2015
  • Connecting two or more sub-cells is a simple and effective way of improving power conversion efficiency (PCE) of solar cells, and the theoretical efficiency of this tandem cell is known to reach 85~88% of the sum of the sub-cell's efficiencies. There are two ways of connecting sub-cells in the tandem structure, i.e. parallel and series connection. The parallel connection can increase the short circuit current (Jsc) and the series connection can increase the open circuit voltage (Voc). Although various tandem structures have been studied, the full use of incident light and optimization of cell efficiency is still limited. In this work, we designed series tandem solar cells consisting of lead sulfide (PbS) quantum dots/zinc oxide-based QDSC and zinc phthalocyanine (ZnPc)/C60-based small molecule OSCs. It is expected that the loss of the incident light is minimized because the absorption range of the PbS quantum dots and ZnPc is significantly different, and the Voc increases according to the Kirchhoff's law.

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Recent insights into the role of ChREBP in intestinal fructose absorption and metabolism

  • Lee, Ho-Jae;Cha, Ji-Young
    • BMB Reports
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    • v.51 no.9
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    • pp.429-436
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    • 2018
  • Fructose in the form of sucrose and high fructose corn syrup is absorbed by the intestinal transporter and mainly metabolized in the small intestine. However, excess intake of fructose overwhelms the absorptive capacity of the small intestine, leading to fructose malabsorption. Carbohydrate response element-binding protein (ChREBP) is a basic helix-loop-helix leucine zipper transcription factor that plays a key role in glycolytic and lipogenic gene expression in response to carbohydrate consumption. While ChREBP was initially identified as a glucose-responsive factor in the liver, recent evidence suggests that ChREBP is essential for fructose-induced lipogenesis and gluconeogenesis in the small intestine as well as in the liver. We recently identified that the loss of ChREBP leads to fructose intolerance via insufficient induction of genes involved in fructose transport and metabolism in the intestine. As fructose consumption is increasing and closely associated with metabolic and gastrointestinal diseases, a comprehensive understanding of cellular fructose sensing and metabolism via ChREBP may uncover new therapeutic opportunities. In this mini review, we briefly summarize recent progress in intestinal fructose metabolism, regulation and function of ChREBP by fructose, and delineate the potential mechanisms by which excessive fructose consumption may lead to irritable bowel syndrome.

Design and Analysis of Electromagnetic Wave Absorbing Structure Using Layered Composite Plates (적층 복합재 판을 이용한 전자기파 흡수 구조체의 설계)

  • 오정훈;홍창선;오경섭;김천곤;이동민
    • Composites Research
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    • v.15 no.2
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    • pp.18-23
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    • 2002
  • The absorption and the interference shielding of the problems thor both commercial and military purposes. In this study, the minimization of the electromagnetic wale reflections using composite layers with different dielectric properties was performed. Dielectric constants were measured for glass/epoxy composites containing conductive carbon blacks and carbon/epoxy fabric composites. Using the measured permittivities of the composites having various carbon black contents, the optimal electromagnetic wave absorbing structure in X-band(8.2GHz-12.4GHz) was determined. The optimal multi-layered composite plates have the thickness of 2.6mm. The maximum reflection loss is -30dB at 10GHz, and the bandwidth haying the absorptivity lower than -l0dB is about 2GHz.