• 제목/요약/키워드: abnormal growth

검색결과 708건 처리시간 0.025초

수술후 10년 이상 장기 생존 담도폐쇄증 환장에서의 영양상태 및 임상적 특성에 관한 분석 (Clinical & Nutritional Assessments of Long-term Survivors of Biliary Atresia)

  • 전용순;김우기
    • Advances in pediatric surgery
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    • 제4권2호
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    • pp.125-130
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    • 1998
  • To assess the clinical and nutritional status of long-term survivors of biliary atresia, history taking, medical record review, physical examination (height, weight, MAC, TSF), blood tests (LFT, prothrombin time, platelet count, prealbumin, calcium) and liver needle biopsy were performed in 12 patients in whom Kasai procedure were performed more than 10 years ago at Department of Pediatric Surgery in Seoul National University Hospital. None were below the 5th percentile in height and weight. TSF was above the 75th percentile in all patients and showed good subcutaneous fat deposition. MAC was above the 5th percentile in all patients. Serum prealbumin level was abnormal in 2 patients with abnormal liver function and revealed visceral protein malnutrition. Serum calcium level was decreased below normal range in 4 patients with abnormal liver function. One patient had mild ascites. Five patients had abnormal liver function and 7 patients showed clinical manifestation of portal hypertension. Liver needle biopsy was performed in 5 patients and no cirrhotic change was observed. Although some patients who have survived for more than 10 years after Kasai procedure developed protein malnutrition and vitamin deficiencies, growth and development and nutritional status were generally satisfactory. Five patients(42%) showed normal liver function and no portal hypertension. In conclusion, Kasai procedure is satisfactory as a primary treatment in biliary atresia but significant portion of long-term survivors had abnormal liver function and portal hypertension. Continuous and careful follow-up is necessary to determine when liver transplantation may be indicated.

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Over-expression of BvMTSH, a fusion gene for maltooligosyltrehalose synthase and maltooligosyltrehalose trehalohydrolase, enhances drought tolerance in transgenic rice

  • Joo, Joungsu;Choi, Hae Jong;Lee, Youn Hab;Lee, Sarah;Lee, Choong Hwan;Kim, Chung Ho;Cheong, Jong-Joo;Choi, Yang Do;Song, Sang Ik
    • BMB Reports
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    • 제47권1호
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    • pp.27-32
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    • 2014
  • Plant abiotic stress tolerance has been modulated by engineering the trehalose synthesis pathway. However, many stress-tolerant plants that have been genetically engineered for the trehalose synthesis pathway also show abnormal development. The metabolic intermediate trehalose 6-phosphate has the potential to cause aberrations in growth. To avoid growth inhibition by trehalose 6-phosphate, we used a gene that encodes a bifunctional in-frame fusion (BvMTSH) of maltooligosyltrehalose synthase (BvMTS) and maltooligosyltrehalose trehalohydrolase (BvMTH) from the nonpathogenic bacterium Brevibacterium helvolum. BvMTS converts maltooligosaccharides into maltooligosyltrehalose and BvMTH releases trehalose. Transgenic rice plants that over-express BvMTSH under the control of the constitutive rice cytochrome c promoter (101MTSH) or the ABA-inducible Ai promoter (105MTSH) show enhanced drought tolerance without growth inhibition. Moreover, 101MTSH and 105MTSH showed an ABA-hyposensitive phenotype in the roots. Our results suggest that over-expression of BvMTSH enhances drought-stress tolerance without any abnormal growth and showes ABA hyposensitive phenotype in the roots.

대기업-중소기업의 상생협력 정책이 기업가치에 미치는 영향: 이벤트연구방법론을 기반으로 (Evaluating the Impact of Win-Win Growth Policy Announcements between Large Firms and SMEs on the Market Value of Firms)

  • 백종현;권순범;최병구
    • 지식경영연구
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    • 제13권5호
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    • pp.139-160
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    • 2012
  • Win-win growth between large companies and small and medium enterprises (SMEs) become a critical encomic and social issue in Korea. Korea government has been attempted to establish strong policy to build right win-win relationship between large companies and SMEs. Along with this strong drive from Korea government, a variety of strategies that enhance win-win relationships between large companies and SMEs have been adopted. Win-win growth policy is expected to provide positive impact on sustainable competitive advantage of firms. Therefore, many studies have focused on the win-win growth policy success factors, type of the policy, and the results of the policy. Although there is much literature on the win-win growth policy, the effects of win-win policy on firm value is not well understood. We addressed this issue by exploring how win-win growth policy influences a firm's market value using event study methodology. We evaluated the cumulative abnormal returns for win-win growth policy announced by Korean large firms from 2004 to 2012. The results of this study insisted that the announcements of win-win growth policy show negative impact on firm's market value, which is not consistent with previous studies. The findings of this study offer insights that may help government policy makers and managers to revise their policy for better outcomes of their win-win growth policy.

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하추기 이상 저온하에서 뽕나무 발육부진요인과 추비에 의한 생육증진 (Mulberry Growth Promotion by Nitrogen Application under Abnormally Wet and Cool Weather Conditions)

  • 이원주;윤명근
    • 한국잠사곤충학회지
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    • 제36권2호
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    • pp.110-114
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    • 1994
  • 93년 뽕나무 생육기에 내습한 이상저온 현상에 대한 감수정도와 요인을 분석하는 한편, 경감대책을 마련하기 위해 수원 잠업시험장과 충남 공주군에 소재한 충남도 잠업사업소 등 2개 장소에서 방임구를 대조로 요소엽면시비구 (요소 0.7%), 잠시비료 8호구 (요수 0.7%와 미량요소 함유), 그리고 질소질 6kg/10a를 황산암모늄으로 덧거름한 4개처리구를 설치하여 시험결과 다음과 같았다. 1. 여름베기후 뽕나무 생육기간 중인 6월 하순-9월 상순사이에 전국적으로 평년대비 평균기온은 1.4$^{\circ}C$ 낮았으며, 강우량은 83mm나 많았으며, 그 결과 가을뽕 수량은 평년대비 16.4% 감수되었는데, 뽕잎의 감수에 더 크게 영향하는 요인은 기온의 저하보다는 강우량의 과다에서 오는 질소질의 용탈에 원인하는 것으로 판단되었다. 2. 이상저온 내습시 생육부진을 막기 위해 요소 및 잠시비료 8호를 각각 엽면시비한 구보다는, 질소질 6kg/10a를 덧거름으로 시비한 구에서 5% 수준에서 통계적인 유의차가 인정될 정도로 증수되었다. 3. 뽕잎분석 결과 전질소 함량은 요소살포구와 질소질 덧거름구에서 방임구 3.53% 대비 0.53% 높았다.

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