• 한국원자력학회:학술대회논문집
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• 한국원자력학회 2001년도 춘계학술발표회요약집
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• pp.120.2-120
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• 2001

• 한국식물학회:학술대회논문집
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• 한국식물학회 1999년도 춘계학술발표대회:발표논문요지록
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• pp.11-11
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• 1999

• Clinical and Experimental Reproductive Medicine
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• 제44권2호
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• pp.90-95
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• 2017

Objective: We investigated whether the insemination method (in vitro fertilization [IVF] or intracytoplasmic sperm injection [ICSI]) affected morphokinetic events and abnormal cleavage events in embryonic development. Methods: A total of 1,830 normal fertilized embryos were obtained from 272 IVF and ICSI cycles that underwent ovum retrieval culture using a time-lapse system (Embryoscope) from June 2013 to March 2015. All embryos were investigated by a detailed time-lapse analysis that measured the developmental events in the hours after IVF or ICSI insemination. Results: No significant differences were observed between the two groups regarding clinical outcomes (p>0.05). ICSI-derived embryos showed significantly faster morphokinetics than those derived from conventional IVF, from the time to pronuclear fading to the time to 6 cells (p<0.05). However, no significant differences were found from the time to 7 cells to the time to expanded blastocyst (p>0.05). There were no differences in abnormal cleavage events between the two groups (p>0.05); they showed the same rates of direct cleavage from 1 to 3 cells, 2 multinucleated cells, 2 uneven cells, and reverse cleavage. Conclusion: The morphokinetics of embryo development was found to vary between IVF- and ICSI-fertilized oocytes, at least until the 6-cell stage. However, these differences did not affect the clinical outcomes of the embryo. Additionally, no significant differences in abnormal cleavage events were found according to the fertilization method.

• Advances in pediatric surgery
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• 제4권2호
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• pp.125-130
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• 1998

To assess the clinical and nutritional status of long-term survivors of biliary atresia, history taking, medical record review, physical examination (height, weight, MAC, TSF), blood tests (LFT, prothrombin time, platelet count, prealbumin, calcium) and liver needle biopsy were performed in 12 patients in whom Kasai procedure were performed more than 10 years ago at Department of Pediatric Surgery in Seoul National University Hospital. None were below the 5th percentile in height and weight. TSF was above the 75th percentile in all patients and showed good subcutaneous fat deposition. MAC was above the 5th percentile in all patients. Serum prealbumin level was abnormal in 2 patients with abnormal liver function and revealed visceral protein malnutrition. Serum calcium level was decreased below normal range in 4 patients with abnormal liver function. One patient had mild ascites. Five patients had abnormal liver function and 7 patients showed clinical manifestation of portal hypertension. Liver needle biopsy was performed in 5 patients and no cirrhotic change was observed. Although some patients who have survived for more than 10 years after Kasai procedure developed protein malnutrition and vitamin deficiencies, growth and development and nutritional status were generally satisfactory. Five patients(42%) showed normal liver function and no portal hypertension. In conclusion, Kasai procedure is satisfactory as a primary treatment in biliary atresia but significant portion of long-term survivors had abnormal liver function and portal hypertension. Continuous and careful follow-up is necessary to determine when liver transplantation may be indicated.

• Journal of Chest Surgery
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• 제41권5호
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• pp.636-639
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• 2008

우관상동맥 이상기시는 급사, 심근경색, 부정맥이나 실신을 일으킬 수 있으며, 관상동맥경화를 진행시키는 요인으로 여겨진다. 우관상동맥 이상기시에서의 심근 허혈의 기전은 확실하지 않으며, 여러 가지 수술적 치료방법이 보고되고 있다. 다절편 전산화흉부단층촬영은 비정상적인 관상동맥의 경로와 심근 허혈의 기전을 밝혀 적절한 수술적 치료를 결정하는데 도움이 된다. 저자들은 우관상동맥 이상기시와 함께 급성 심근 경색이 있었던 환자에 있어서 관상동맥우회술로 치료한 증례를 보고하는 바이다.

• 산업융합연구
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• 제21권8호
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• pp.43-49
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• 2023

2018년부터 기후변화에 따른 폭염과 한파에 의해 사회기반시설에 점증적으로 많은 피해를 미치고 있다. 최근 4년간 기후변화에 따른 영향 중에 냉해에 대한 피해가 매년 증가하여 특정 지역에 국한되었던 피해가 이제는 전국에 걸쳐서 나타나고 있으며, 이를 최소화하기 위한 각계각층의 전문가들에 의한 노력이 집중되고 있다. 그러나 불연속적으로 측정되는 데이터들 속에서 지역 특색을 반영하고자 하는 기존 연구들에서는 갑작스럽게 발생하는 이상 저온에 대한 실시간 관측 연구는 쉽지 않은 상황이다. 본 연구에서는 냉해 발생에 영향을 미치는 기상 데이터를 기준으로 냉해 피해가 발생하였던 시점의 기상 패턴을 탐색한 후 이상저온 발생 시점을 확인할 수 있는 알고리즘 패턴 개발을 하였다. 본 연구의 결과물은 과거의 데이터에 의존하지 않고 실시간으로 발생하는 데이터에 의한 이상저온이 발생한 시점을 시간 시점에서 확인할 수 있다는 점에서 지역적 기상 편차를 의식하지 않고 확인이 가능하다는 점에서, 이상저온 발생 시점 데이터를 확보할 수 있다는 점에서 관련 분야에 많은 도움이 될 것으로 기대할 수 있다.

• 한국수산과학회지
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• 제48권5호
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• pp.696-703
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• 2015

We investigated the characteristics of embryonic and abnormal organ development in haploid olive flounder, Paralichthys olivaceus, by comparing egg development and histological sections in haploid and diploid individuals. After the mid-blastula transition, abnormal development was observed in haploid fish, including delayed epiboly and malformation of the germ ring and embryonic body. In haploid flounder, Kupffer’s vesicles are irregularly shaped and of variable size compared to diploids. The embryonic body of haploids was shorter and broader than that of diploids and the tail length and size were variable. Most haploid embryos failed to hatch and the few larvae that did, did not survive for more than 6 h. The histological analysis of haploid larvae revealed deformed development in diverse organs, including the eye, otic vesicles, notochord, and neural tube. These results may be related to an abnormality in the axial system of haploid larvae. This study confirmed that the abnormalities of haploid olive flounder were similar to the reported characteristics of haploid syndrome. The abnormalities are caused by delayed epiboly and involution and deformity of Kupffer’s vesicle during egg development.

• 대한음성학회:학술대회논문집
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• 대한음성학회 2007년도 한국음성과학회 공동학술대회 발표논문집
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• pp.155-157
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• 2007

Objective : There are close relationship between intraoral abnormal structure and speech-functional problem. Patients with cleft palate & ankyloglossia are typical examples. Patients with abnormal structure can be repaired toward normal structure by operation. Ankyloglossia may cause functional limitation - for example, speech disorder - even if adequate surgical treatment were done. And, each individuals have each speech disorders. The objective of this study is to evaluate the speechs of childrens with ankyloglossia, and to determine whether ankyloglossia is associated with articulation problem. We wanted to present criteria for indication of frenectomy. Study design The experimental group is composed of 10 childrens who visited our department of oral and maxillofacial surgery, dental hospital, Chonbuk university, due to ankyloglossia and articulation problem,. The average age is 5 Y 7M, M : F ratio is 4 : 1 at the time of speech test. The VPI consonant discrimination degree, PPVT, PCAT, Nasometer II, Visi-Pitch test result were obtained from each group. Result : There was significant difference for 'language development' through PPVT. Except 3 members of experimental group, all remainder showed retardation for 'language development'. For 'errored consonant rate', data showed more higher scores in alveolar consonant. There 'consonant error' in experimental group, mostly showed 'alveolar consonant', also a major modality of 'consonant error' was mostly distortion. Conclusion : We can judge the severity of ankyloglossia patient by examinig language development degree & speech test of 'alveolar consonant' . And we can make a decision for frenulotomy using these results.

• 한국동물생명공학회지
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• 제37권3호
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• pp.162-168
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• 2022

Mecoprop-p, a chlorophenoxy herbicide, has been widely used since the 1980s. Due to its high water solubility, it could be detected in the aquatic environment, as it has already been detected in the surface water or groundwater in several countries. The toxicity of other chlorophenoxy herbicides has been reported; however, there are few studies on the toxicity of mecoprop-p, one of the chlorophenoxy herbicides, on aquatic organisms. Here, we investigated the toxic effects of mecoprop-p using zebrafish. After mecoprop-p exposure, we observed that the zebrafish larvae eyes did not form normally, heart edema was generated, and the body length was shortened. The number of cells undergoing apoptosis also increased in the anterior part including head, heart, and yolk sac of the mecoprop-p-treated zebrafish compared to the untreated controls. Moreover, cardiovascular structures, including the heart and aortic arches, were also malformed after exposure to mecoprop-p. Therefore, our results suggest that mecoprop-p could cause abnormal development in zebrafish larvae and there is also a high possibility that mecoprop-p would be toxic to other aquatic organisms.

• Applied Biological Chemistry
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• 제49권3호
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• pp.202-208
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• 2006

전체 참외생산량에서 25%를 차지하는 이상발효 참외는 농가수익과 환경오염의 측면에서 많은 손실을 발생시키고 있으며 이를 해결하기 위해서는 상품성과 가격경쟁력을 갖춘 참외의 가공기술 개발이 필요하다. 따라서 본 연구에서는 이상발효 참외를 발효식품용 원료로서 사용하기 위한 기본적인 요건이 잘 갖추어진 재료임을 감안하여 참외주 용도로의 이용성을 제고하기 위한 전단계로 정상과와 이상과의 품질을 검정하고 원료처리별 저장성과 착즙방법을 검토하였다. 정상과에 비해 이상발효과는 높은 수분함량과 낮은 탄수화물함량을 나타내었으며, 이는 발효에 의해 당성분이 발효산물로 전환되었기 때문으로 추측된다. 정상과 및 발효과의 온도별 저장기간은 $4^{\circ}C$의 저온상태에서는 각각 25일, 7일이였고 실온상태는 8일, 4일까지 가능하였다. 발효용 참외의 보관방법은 저온$(4^{\circ}C)$에서는 세절 후 구연산을 1.5% 첨가한 상태에서는 30일, 세절 후 플라스틱 필름팩에 밀봉하여 냉동$(-20^{\circ}C)$상태에서는 1년간 저장이 가능하였다.