• 대한기계학회:학술대회논문집
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• 대한기계학회 2001년도 춘계학술대회논문집A
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• pp.920-925
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• 2001

A study on the topology optimization of a multi-spectral camera for space-use is presented. A multi-spectral camera for space-use experiences degradation of optical image in the space, which can not be detected on the optical test bench on the earth. An optical surface deformation of a primary mirror, which is a principal component of the camera system, under the self-weight loading is an important factor affecting the optical performance of the whole camera system. In this study, topology optimization of the primary mirror of the camera is presented. Total mass of the primary mirror is given as a constraint to the optimization problem. The sensitivities of the objective function and constraint are calculated by direct differentiation method. Optimization procedure is carried out by an optimality criterion method using the sensitivities of the objective function and the constraint. As a preliminary example, topology optimization considering a self-weight loading is treated. For practical use, the polishing pressure is included as a loading in the topology optimization of the primary mirror. Results of the optimized design topology for the primary mirror with varying mass ratios are presented.

• 한국환경독성학회:학술대회논문집
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• 한국환경독성학회 2004년도 춘계학술대회
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• pp.47-60
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• 2004

Higher plants can be valuable genetic assay systems for monitoring environmental pollutants and evaluating their biological toxicity. Two assays are considered ideal for in situ monitoring and testing of soil, airborne and aqueous mutagenic agents; the Tradescantia stamen hair assay for somatic cell mutations and the Tradescantia micronucleus assay for chromosome aberrations. Both assays can be used for in vivo and in vitro testing of mutagens. Since higher plant systems are now recognized as excellent indicators and have unique advantages over in situ monitoring and screening, higher plant systems could be accepted by regulatory authorities as an alternative first-tier assay system for the detection of possible genetic damages resulting from the pollutants or chemicals used and produced by industrial sectors. It has been concluded that potential mutagen and carcinogen such as the heavy metals among indoor air particulates, volatile compounds in the working places, soil, and water pollutants contribute to the overall health risk. This contribution can be considerable under certain circumstances. It is therefore important to identify the level of genotoxic activity in the environment and to relate it to the biomarkers of a health risk in humans. The results from the higher plant bioassays could make a significant contribution to assessing the risks of pollutants and protecting the public from agents that can cause mutation and/or cancer. The plant bioassays, which are relatively inexpensive and easy to handle, are recommended for the scientists who are interested in monitoring pollutants and evaluating their environmental toxicity to living organisms.

• 한국환경생물학회:학술대회논문집
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• 한국환경생물학회 2004년도 학술대회
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• pp.1-15
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• 2004

Higher plants can be valuable genetic assay systems for monitoring environmental pollutants and evaluating their biological toxicity. Two assays are considered ideal for in situ monitoring and testing of soil, airborne and aqueous mutagenic agents; the Tradescantia stamen hair assay for somatic cell mutations and the Tradescantia micronucleus assay for chromosome aberrations. Both assays can be used for in vivo and in vitro testing of mutagens. Since higher plant systems are now recognized as excellent indicators and have unique advantages over in situ monitoring and screening, higher plant systems could be accepted by regulatory authorities as an alternative first-tier assay system for the detection of possible genetic damages resulting from the pollutants or chemicals used and produced by industrial sectors. It has been concluded that potential mutagen and carcinogen such as the heavy metals among indoor air particulates, volatile compounds in the working places, soil, and water pollutants contribute to the overall health risk. This contribution can be considerable under certain circumstances. It is therefore important to identify the level of genotoxic activity in the environment and to relate it to the biomarkers of a health risk in humans. The results from the higher plant bioassays could make a significant contribution to assessing the risks of pollutants and protecting the public firom agents that can cause mutation anuor cancer. The plant bioassays, which are relatively inexpensive and easy to handle, are recommended for the scientists who are interested in monitoring pollutants and evaluating their environmental toxicity to living organisms.

• 한국식품위생안전성학회지
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• 제11권1호
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• pp.41-50
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• 1996

The yields of solvent fraction of irradiated red ginseng powder were increased in the order of petroleum ether(PE)

• 한국광학회지
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• 제10권2호
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• pp.120-127
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• 1999

Head-Up Display(HUP)에 사용되는 홀로그래픽 광결합기의 회절 효율 및 결상 특성을 분석하고 제작하였다. Kogelnik의 결합파이론을 통해 반사형 체적 홀로그램에 대한 각도 및 분광 대역 특성을 수치계산하고 홀로그래픽 광학소자에서의 파장 변화에 의한 색수차의 최소화 방법을 HUD의 재생각 및 초점거리 보정에 응용하였다. 또한 자동차에 사용되는 형태로 등각형(conformal type)과 비등각형(non-conformal type)의 홀로그래픽 광결합기를 비교하고 대역 특성을 실험적으로 분석하였다. 실제적으로 등각형 보다 넓은 각도 대역폭을 보이며 광학적 배율(optical power)을 지니는 홀로그래픽 광결합기를 설계, 제작하였다.

• Journal of the Optical Society of Korea
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• 제19권6호
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• pp.604-613
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• 2015

An unobstructed off-axis two-mirror system is presented in this paper. First a suitable initial configuration is established based on third-order aberration theory. In order to achieve a wide field of view (FOV) with high image quality , the diffractive mirror is adopted in the two-mirror system to increase the optimization freedom and the aberration relationship between diffractive phase coefficients and Zernike coefficients is derived. Furthermore, a complete comparison design example with a focal length of 1200 mm, F-number of 12, and FOV of 40° × 2° is given to verify the aberration correction ability of the diffractive mirror. The system average wavefront error is 0.007 λ (λ=0.6328 μm) developed from 0.061 λ when the system didn’t adopt the diffractive mirror. In this system the phase modulation function of the diffractive mirror is established as an even function of x, so we could obtain a symmetrical imaging quality about the tangential plane, and the symmetric aberration performance also brings considerable convenience to alignment and testing for the system.

• Journal of the Optical Society of Korea
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• 제18권5호
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• pp.574-581
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• 2014

This paper presents the design and evaluation of the optical zoom system for an LWIR camera. The 12.8operating wavelength range of this system is from $7.7{\mu}m$ to $12.8{\mu}m$. Through a paraxial design and optimization process, we have obtained the extended four-group inner-focus zoom system with focal lengths of 10 to 100 mm, which consists of the six lenses including four aspheric surfaces and two diffractive surfaces. The diffractive lenses were used to balance the higher-order aberrations, and its diffraction properties were evaluated by scalar diffraction theory. We have calculated the polychromatic integrated diffraction efficiency and the MTF drop generated by background noise. The f-number of the zoom system is F/1.4 at all positions. Fields of view are given by $51.28^{\circ}{\times}38.46^{\circ}$ at wide field and $5.50^{\circ}{\times}4.12^{\circ}$ at narrow field positions. In conclusion, this design procedure results in a $10{\times}$ compact zoom lens system useful for an LWIR camera.

• 한국생물정보학회:학술대회논문집
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• 한국생물정보시스템생물학회 2006년도 Principles and Practice of Microarray for Biomedical Researchers
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• pp.71-76
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• 2006

Comparative genomic hybridization (CGH) is a technique for studying chromosomal changes in cancer. As cancerous cells multiply, they can undergo dramatic chromosomal changes, including chromosome loss, duplication, and the translocation of DNA from one chromosome to another. Chromosome aberrations have previously been detected using optical imaging of whole chromosomes, a technique with limited sensitivity, resolution, quantification, and throughput. Efforts in recent years to use microarrays to overcome these limitations have been hampered by inadequate sensitivity, specificity and flexibility of the microarray systems. The oligonucleotide CGH microarray system overcomes several scientific hurdles that have impeded comparative genomic studies of cancer. This new system can reliably detect single copy deletions in chromosomes. The system includes a whole human genome microarray, reagents for sample preparation, an optimized microarray processing protocol, and software for data analysis and visualization. In this study, we determined the sensitivity, accuracy and reproducibility of the new system. Using this assay, we find that the performance of the complete system was maintained over a range of input genomic DNA from 5 ug down to 0.15 ug.

• 한국전문물리치료학회지
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• 제7권4호
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• pp.1-7
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• 2000

이 연구의 목적은 만성요통 여성 환자들에서 나타나는 자세 이상을 평가하고 방사선적 변수들과 임상적인 변수들과의 상관성을 알아보는 것이다. 이 연구의 대상자는 만성요통 여성 환자 38명과 대조군 32명이었다. 변수의 측정은 모든 대상자들이 이완된 자세로 기립한 상태에서 방사선 검사를 실시한 후 경추전만각, 흉추후만각, 요추전만각, 그리고 요추경사각을 측정하였다. 대상자들의 연령과 통증기간은 의무기록지를 참고하였다. 자료분석은 요통군과 대조군의 방사선적 변수들 간의 유의한 차이가 있는지를 알아보기 위해 독립된 t-검정을 시행하였고, 방사선적 변수들과 임상적 변수들과의 상관성을 알아보기 위해 피어슨 상관분석을 시행하였다. 연구결과 만성요통 환자군과 대조군사이의 경추전만각(p<.05), 요추전만각(p<.001), 그리고 천추경사각(p<.01)에서 통계학적으로 유의한 차이가 보였다. 통증기간은 요추전만각과 통계적학으로 유의한 상관관계가 있었으며(p<.05), 경추전만각은 흉추후만각과 통계학적으로 유의한 상관관계가 있었다(p<.05). 또한 흉추후만각, 요추전만각, 그리고 천추경사각은 각각 상호간에 상관관계가 있었다(p<.05). 만성요통은 요추만곡의 변화를 초래하여 흉추부 및 경추부의 자세이상을 유발할 수 있다. 그러므로 요통으로 인하여 올 수 있는 신체 전반적인 자세이상을 미리 예측하고 이를 교정하여야만 장기적으로 올 수 있는 합병증들을 예방할 수 있을 것이다.

• 천문학회보
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• 제38권1호
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• pp.72.2-72.2
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• 2013

An off-axis telescope has several advantages in optical performance comparing with a conventional on-axis telescope. However, in general, an off-axis telescope has a narrow field of view due to the linear astigmatism caused by the asymmetric structure. It was shown in the previous work that the linear astigmatism can be eliminated by properly configuring parameters in a confocal off-axis reflector system. Furthermore, the third order aberrations of a confocal off-axis telescope can be minimized by optimizing the shape of the mirrors. Despite many advantages, the confocal off-axis telescopes have been evaded because of difficulties of off-axis mirror fabrication, alignment process and unaccustomed off-axis baffle design. The baffle for the off-axis telescope should be designed considering that the effects of stray lights are different because of the asymmetry of off-axis system. In this poster, the design, manufacturing, and test for the baffle and housing of an off-axis telescope are presented.