• 대한의용생체공학회:의공학회지
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• 제17권2호
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• pp.227-234
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• 1996

This paper is the study of the diffusion constant in order to calculate the percent oxygenation and percent blood volume using reflectance light within biological tissue. The diffusion constant play major role in percent oxygenation and percent blood volume and varies with the biological material such as hemolyzed blood, whole blood, dermis and epidermis in vivo tissue. The diffusion constant can be modeled to consist of a contribution from bloodless tissue and blood present in tissue. The reflectance light for experimental are red light of 660nm, infrared light of 880nm, green light of 569nm. The correlation between the diffusion constant and biological tissue was analyzed by the intensity of reflectance light at different depth within human limb. The reflectance light was changed in response to physiological changes within biological tissue. The data for diffusion constant were obtained at different depth beneath the surface of the skin and will be utilized to amen the percent oxygenation and percent blood volume.

• Mycobiology
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• 제42권2호
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• pp.152-157
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• 2014

The iron uptake and utilization pathways play a critical role in allowing human pathogens, including Cryptococcus neoformans, the causative agent of fatal meningoencephalitis, to survive within the mammalian body by competing with the host for iron. Here we show that the iron regulon is also required for diverse environmental stress responses and that in C. neoformans, it is regulated by the high-osmolarity glycerol response (HOG) pathway. Between CFO1 and CFO2, two ferroxidase genes in the iron regulon, CFO1 but not CFO2 was induced during oxidative and osmotic stress. Interestingly, we found that the HOG pathway repressed basal expression of both CFO1 and CFO2. Furthermore, when the HOG pathway was blocked, CFO2 also responded to oxidative and osmotic stress and the response of CFO1 was increased. We also established that CFO1 plays a major role in responding and adapting to diverse environmental stresses, including oxidative and genotoxic damage, osmotic fluctuations, heavy metal stress, and stress induced by cell membrane destabilizers. Therefore, our findings indicate that in C. neoformans, the iron uptake and utilization pathways are not only required for iron acquisition and survival, but also play a significant role in the environmental stress response through crosstalk with the HOG pathway.

• 한국문헌정보학회지
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• 제22권
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• pp.1-27
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• 1992

Librarians long ago proclaimed themselves professionals. Until recently, however, librarians and information professionals gave very little thought to professional ethics, which have corne to play an increasingly important role in all areas in modern society. They have been stimulated to consider their specific domain within an ethical context now. Professional norms express obligations which include prescribing standards, principles of responsibilities, and rules of duties. Professional codes attempt to formulate the norms of professional ethics and are the basis for disciplinary measures of various kinds. This paper discusses professional properties and characteristics of libarianship with a special reference to the code of professional ethics. The codes of ethics of the American Library Association, the Library Association, and of the Japanese Library Association have been reviewed and compared. The arguments on the enforcibility of the professional codes of ethics, therefore, on their effectiveness have been discussed. Author concludes that, despite some doubts on the practical effectiveness of the ethics code expressed by a number of scholars, a code of ethics is very much required in the information professions. Properly disseminated, a code would enhance the status and standing of the profession by demonstrating concerns for the maintenance of the highest possible level of standards of professional services. It would also play an important role in raising consciousness of the clients by communicating the value of the works.

• 한국컴퓨터정보학회논문지
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• 제24권8호
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• pp.45-50
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• 2019

Oculus Rift is the most universal VR (virtual Reality) headset for gamers and FPS (First Person Shooting) is the most suitable game genre to play with VR. Using VR can increase the player's sense of reality and make them feel as though they are in direct contact with the enemy while battling. The suggested VR game is a first person game where the player must defend a specific target against the surging enemy all within the time limit. Many objects will need to be used in this method. Object pooling will be used in order to manage all the numerous objects. When an object is repeatedly created and deleted it typically overwhelms the memory. To resolve this issue the game initially summons the object at the beginning of the scene and afterwards only uses the object when needed, lessening the burden on the memory. A ranking system is implemented to keep the game records in order to stimulate a competitive spirit between the players, and the game has received positive response during test play among college students in their 20s.

• Animal Bioscience
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• 제37권2_spc호
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• pp.323-336
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• 2024

Molecular hydrogen (H₂) and formate (HCOO^-) are metabolic end products of many primary fermenters in the rumen ecosystem. Both play a vital role in fermentation where they are electron sinks for individual microbes in an anaerobic environment that lacks external electron acceptors. If H₂ and/or formate accumulate within the rumen, the ability of primary fermenters to regenerate electron carriers may be inhibited and microbial metabolism and growth disrupted. Consequently, H₂- and/or formate-consuming microbes such as methanogens and possibly homoacetogens play a key role in maintaining the metabolic efficiency of primary fermenters. There is increasing interest in identifying approaches to manipulate the rumen ecosystem for the benefit of the host and the environment. As H₂ and formate are important mediators of interspecies interactions, an understanding of their production and utilization could be a significant starting point for the development of successful interventions aimed at redirecting electron flow and reducing methane emissions. We conclude by discussing in brief ruminant methane mitigation approaches as a model to help understand the fate of H₂ and formate in the rumen ecosystem.

• 대한교통학회지
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• 제1권1호
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• pp.43-47
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• 1983

Within the conventional transportation planning process, "trip distribution" has a significant role to play. The most widely applied trip distribution model is the gravity model, for which Wilson provided the theoretical basis in 1967. The concept of the gravity model, however, still remains ambiguous if we analyze the "trip distribution" with a disaggregate data set. Thus, this paper hypothesizes that the gravity technique is still valid even with the disaggregate data set, by proving that the estimated coefficients of the gravity model, which is derived under the principle of entropy maximization, are identical with those of the multinomial logit model, which is derived under the principle of individual utility maximization.tility maximization.

• 농촌의학ㆍ지역보건
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• 제47권1호
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• pp.1-13
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• 2022

Objectives: This study aimed to establish a linkage model involving regional responsible medical institutions after analyzing the existing conditions and deriving problems through qualitative analysis within the community care system. Methods: A total of 14 participants of this study were selected through the snowball sampling method, including 7 community care service providers and 7 service users. As for the research data, primary data were collected through interviews, and as a result of analyzing according to Aday&Anderson' model, a total of 5 catergories, 8 topics, and 22 sub theme were derived. Results: The problem derived from the interview is that division services are provided for each institution due to the absence of a key central institution of community care system, and users' commercial institutions is unclear. The second is the inconsistency between the needs and supply for community care, resulting in a possibility of delay in returning to the community after discharge. Based on these problems, it is necessary to unify it as an community care window of the Dong-community center. In addition, there is a need for public health centers to play an active role, and to establish a public-private joint system with the Health and Living Support Center to establish a model that can play a certain role. Conclusions: Therefore, based on the results of this study, it can be used as basic data when constructing community care model and applying it as an expanded model in the future.

• IMMUNE NETWORK
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• 제1권1호
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• pp.26-31
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• 2001

Background : Follicular dendritic cells (FDCs) play key roles during T cell-dependent humoral immune responses by allowing antigen-specific B cells to survive, proliferate, and differentiate within the FDC networks of secondary follicles, i.e., germinal centers (GC). Methods: A novel monoclonal antibody, 3C8, was generated by immunizing with an FDC line HK, in order to understand the molecular signals involved in the FDC-B cell interactions in the microenvironment of the GC. Results: The 3C8 antibody did not bind to mononuclear cells, including T cells, B cells, and monocytes. Murine L929 and human skin fibroblasts exhibited no or little reactivity to 3C8. However, 3C8 specifically recognized HK cells by flowcytometry. Furthermore, the antigen recognized by 3C8 was restricted to the GC of the human tonsil. Dendritic networks of the GC were intensely stained by 3C8, but cells outside the GC were not. Conclusion: Our results suggest that the antigen 3C8 may play some unique role on FDCs during the GC reactions.

• 한국게임학회 논문지
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• 제20권2호
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• pp.101-112
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• 2020

본 연구는 <오버워치>를 통해 고수준의 플레이어가 되는 과정에서 게임 내 협력을 위한 희생이 어떻게 수행되는가에 대해 살펴보았으며 주요 결과는 다음과 같다. 첫째, 낮은 경쟁전 점수대에서는 칭찬카드가 공격형-딜러와 지원형-힐러간에 차이가 크게 나타났으며 지원형에게 많은 칭찬카드가 부여되었다. 둘째, 플레이어의 점수가 높아질수록 힐러로부터 딜러에게로 칭찬카드가 더 많이 부여되었다. 셋째, 고점수대의 플레이어들이 힐러역할을 자발적으로 맡음으로써 '자애로운 역할'을 자임하며 팀의 규범을 선도했고 결과적으로 팀 내에서 발생할 수 있는 역할 갈등의 위험을 분산했다. 이로부터 점수대가 높을수록 협력이 강해짐을 확인하였다.

• 한국석유지질학회:학술대회논문집
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• 한국석유지질학회 2000년도 제7차 학술발표회 발표논문집
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• pp.57-72
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• 2000

The Murzuk Basin covers an area in excess of $350,000{\cal}km^2$, and is one of several intra-cratonic sag basins located on the Saharan Platform of North Africa. Compared with some of these basins, the Murzuk Basin has a relatively simple structure and stratigraphy, probably as a result of it's location on a the East Saharan Craton. The basin contains a sedimentary fill which reaches a thickness of about $4,000{\cal}m$ in the basin centre. This fill can be divided into a predominantly marine Paleozoic section, and a continental Mesozoic section. The principal hydrocarbon play consists of a glacial-marine sandstone reservoir of Cambro-Ordovician age, sourced and sealed by overlying Silurian shales. The present day borders of the basin are defined by tectonic uplifts, each of multi-phase generation, and the present day basin geometry bears little relation to the more extensive Early Palaeozoic sedimentary basin within which the reservoir and source rocks were deposited. The key to the understanding of the Cambro-Ordovician play is the relative timing of oil generation compared to the Cretaceous and Tertiary inversion tectonics which influenced source burial depth, reactivated faults and reorganised migration pathways. At the present day only a limited area of the basin centre remains within the oil generating window. Modelling of the timing and distribution of source rock maturity uses input data from AFTA and fluid inclusion studies to define palaeo temperatures, shale velocity work to estimate maximum burial depth and source rock geochemistry to define kinetics and pseudo-Ro. Migration pathways are investigated through structural analysis. The majority of the discovered fields and identified exploration prospects in the Murzuk Basin involve traps associated with high angle reverse faults. Extensional faulting occurred in the Cambro-Ordovician and this was followed by repeated compressional movements during Late Silurian, Late Carboniferous, Mid Cretaceous and Tertiary, each associated with regional uplift and erosion.