• Title/Summary/Keyword: a conformity assessment index

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A Study for the Conformity Assessment on the Natural Dye by HPLC (1) (HPLC를 활용한 천연염료 적합성 평가 연구 (1))

  • Lee, Eun Mi;Oh, Dong Ki;Yoon, Hong Jin;Kim, Jong Hoon
    • Fashion & Textile Research Journal
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    • v.20 no.6
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    • pp.752-758
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    • 2018
  • Due to environmental pollution and human hazards of some synthetic dyes, the global fashion companies are increasingly interested in eco-friendly products, especially natural dye. For the globalization of natural dyeing industry based on this concern, however, there are some deficiencies of standardization, specification, and conformity assessment on natural dyestuffs as well as natural dyeing process. These obstacles should be not only studied but also defined for a commercial transaction. Accordingly, a study for conformity assessment on commercialized natural dyestuffs (red) was conducted by HPLC analysis in this study. As the results of HPLC analysis, alizarin and purpurin, representative index ingredients, were detected in most of the samples, but the index ingredient content in each sample was different. In addition, some samples showed the variety of peaks including the index ingredients and others. It was inferred that the representative index ingredients could be used on the traceability of natural sourced dyestuffs. These results are related to the index ingredient consistency, standardization, and reproducibility of natural dyed products including such as yarns, fabrics, garments, and so on. Therefore, the present study was demonstrated that in order to determine the conformity assessment system for the satisfaction of all stakeholders, the offering of information on the origin, manufacturing process, and index ingredient content of natural dyes should be prioritized.

Evaluation of Efficiency and Conformity of DMAIC-Based Battery Production System Challenge Solving Methodology: A Study on the Applicability for Improvement ("DMAIC 기반 배터리 생산시스템 과제해결방법론"의 효율성 및 적합성 평가: 개선을 위한 적용 가능성 연구)

  • Shin Chul Park;Joo Yeoun Lee;Myoung Sug Chung
    • Journal of the Korean Society of Systems Engineering
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    • v.20 no.spc1
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    • pp.30-44
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    • 2024
  • The DMAIC methodology, which is most familiar to battery production system developers, is partially inadequate in its conformity to utilize battery production system tasks, so it is necessary to improve the function and structure of the methodology, but many battery production system developers use the DMAIC method based on experience, causing side effects such as confusion, delay in tasks, and insufficient performance during tasks. Accordingly, we intend to conduct an empirical study to improve the "efficiency improvement and conformity evaluation method" so that the DMAIC methodology can be used more reasonably and easily. Using the three-stage research model, we derive components that affect conformity through literature and questionnaire surveys in the first stage, use relational characteristics between components in the second stage to confirm the effect on conformity, and use the relational characteristics in the third stage to confirm the possibility of improving efficiency by applying them to the DMAIC methodology in actual cases. Finally, the "Conformity Assessment Index (CAI) equation" based on relational characteristics is established to enable effective conformity evaluation and continuous improvement.

A Study on the Relationship of Change of Mechanical Properties and Carbonyl Index Induced through Short-wavelength Ultraviolet Radiation (254 nm) for High Density Polyethylene (단파장 자외선(254 nm)에 노출된 고밀도 폴리에틸렌 수지의 카르보닐 지수(CI)와 기계적 물성 변화의 관계에 관한 연구)

  • Kim, Chang-Hwan;Shin, Jin-Yong
    • Applied Chemistry for Engineering
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    • v.24 no.2
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    • pp.138-143
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    • 2013
  • This paper studied the possibility to predict a mechanical property variation from changes in created carbonyl bands by irradiating the surface of high-density polyethylene with short-wavelength ultraviolet radiation of 254 nm to induce a fast chemical degradation. The meaning of this study lies in checking whether a mechanical property change with the same chemical property as the induced optical deterioration is caused by using a UVC lamp with high photon energy instead of optical deterioration via xenon arc light source and outdoor exposure test via natural sunlight requiring a long time. The mechanical strength of high-density polyethylene checked by a tensile test and a creep destruction test showed a similar tendency with CI changes. In particular, the yield strength and elongation had a close relationship with the exposure time to ultraviolet radiation. Accordingly, this paper presented a method to grasp the mechanical property change outdoors requiring a long time more fast through the relationship between the mechanical property change and the carbonyl index using a UVC lamp causing the fast surface degradation.

Assessment of Compensator Thickness in Proton Therapy (양성자 치료 시 사용되는 Compensator의 Thickness에 대한 적정성 평가)

  • Park, Yong Soo;Jang, Jun Yeong;Cho, Gwang Hyeon;Park, Yong Cheol;Choi, Byeong Ki
    • The Journal of Korean Society for Radiation Therapy
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    • v.30 no.1_2
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    • pp.35-40
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    • 2018
  • Purpose : The range of force differs from the size of proton energy used in our hospital. The compensator enables to change energy size based on distal thickness which also makes changes in dose rate. Therefore, the purpose of this study is to evaluate the effect of changing the thickness of compensator distal on dose range and beam on time. Subject and Methodology : Five low energy patients who have received proton therapy were selected as subjects for this study. Beam on was checked for the selected patients during the existing therapy. After then, the thickness of distal of compensator was increased by 2 cm up to 14 cm through proton therapy plan system(TPS) for comparative analysis. For the evaluation of dose range, the value of the target's conformity index(CI) and the maximum dose of rear side target's organ at risk(OAR) were compared. Furthermore, to evaluate the effect of therapy time, beam on time was compared by making compensator distal in each thickness. Result : The result of homogeneity index and conformity index of the increased compensator distal showed the same level in all patients. The comparison results of OAR of target rear side showed 7 cGy at spine cord of abdomen at maximum, 88 cGy at eyeball's RT lens, 391 cGy at RT lens of nasal cavity 51 cGy at trachea of the mediastinum, and 661 cGy at a small bowl of the pelvis. The comparison results of the beam on time showed a reduction from 126 seconds to 62 seconds for the abdomen, from 105 seconds to 37 seconds for the eyeball, from 187 seconds to 134 seconds for nasal cavity, from 100 seconds to 40 seconds for mediastinum, from 440 seconds to 118 seconds for the pelvis. Conclusion : The research result showed that as the distal thickness of compensator increased, the size of energy increased. In addition, beam on decreased due to the increase of dose rate. It is expected that the result would help reduce the treatment time and increase the convenience of patients if it is applied to liver patients who need respiratorygated therapy and pediatric patients. However, distal penumbra increased as the size energy increased. Therefore, in treating cases where OAR is in the vicinity of the target rear side, the influence of penumbra should be taken into account in adjusting thickness level of the compensator in proton therapy plan.

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Residual Characteristics and Risk Assessments of Metalaxyl-M and Dinotefuran in Crown Daisy (Metalaxyl-M 및 dinotefuran 입제의 쑥갓 중 잔류 특성 및 위해성 평가)

  • Song, Min-Ho;Yu, Ji-Woo;Kim, Jinchan;Lee, Kwanghun;Ko, Rakdo;Keum, Young-Soo;Lee, Jiho
    • Korean Journal of Environmental Agriculture
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    • v.41 no.2
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    • pp.108-114
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    • 2022
  • BACKGROUND: This study was performed to determine residual characteristics of soil-treated metalaxyl-M and dinotefuran in crown daisy and to evaluate the risks from intake of the residual pesticides in the crop. METHODS AND RESULTS: The pesticide granules were treated in soil on two levels, and the plants samples were collected 51 days after seeding. The analytes were extracted and partitioned using the QuEChERS extraction packet (MgSO4 4 g, NaCl 1 g). The quantitative methods for metalaxyl-M and dinotefuran were validated in linearity, accuracy, and precision. Risk assessments of the pesticides were performed using Korea national nutrition statistics 2019. CONCLUSION(S): The residual concentrations of metalaxyl-M in crown daisy were 0.09-0.10 mg/kg (for the treatment at 6 kg/10 a) and 0.17-0.19 mg/kg (12 kg/10 a), respectively. The residual concentrations of dinotefuran in the crop were 0.53-0.75 mg/kg (3 kg/10 a) and 1.17-1.26 mg/kg (6 kg/10 a). The amounts of pesticides were less than MRL (Maximum Residue Limits) according to the Korean MFDS (Ministry of Food and Drug Safety). The HI (Hazard Index) of metalaxyl-M and dinotefuran for consumers was 0.0075% and 0.2250%, respectively. For females in the age between 50-64, the major consumer group, the HIs of the pesticides were <3%. Considering the consumption of crown daisy, they are not considered to be of toxicological concern.

A Study on the Development and Measurement of Logistics Partners Cooperation Index(LPCI): Focused on the Joint Logistics (물류협력지수의 개발 및 측정에 관한 연구: 공동물류사업을 중심으로)

  • Suh, Sang-Sok;Song, Gwang-Suk;Park, Jong-Woo
    • Journal of Distribution Science
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    • v.14 no.6
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    • pp.107-118
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    • 2016
  • Purpose - Over 90% of Domestic logistics industry is small enterprise and they are experiencing growth stagnation due to price-based competition structure rather than constructing logistics service of high added value. In order to get over this situation and pursue the development of logistics industry, strengthening its competitiveness, through inter-enterprise cooperative network build-up, would be a key alternative. Therefore, in this study, an index for measuring inter-enterprise cooperation level of Joint logistics business will be developed as a typical collaborative business model in logistics industry. Moreover, a strengthening competitiveness method suggests a developmental step and a key management index to mature in logistics industry. Research Design, Data, Methodology - This study is an index development research for measuring inter-enterprise cooperation level of logistics industry. Such a level was measured by performing a survey by targeting enterprises that participated in Joint logistics business. The targeting enterprises are typical cooperative models in logistics industry. Measurement items were developed which were based on the presented items in existing research. Question items were composed of selection type questions as answering Yes/No. They measures implementation status of corporate activity and detailed activity items measuring qualitative level. Total samples were based on 116 enterprise samples including 90 logistics enterprises and 26 shippers. In addition, by evaluating the importance for Joint logistics business recognition with personnel working level, the weight of measuring variable was extracted. This study has built an assessment tools (LPCI) on Joint logistics business cooperation level in a situation where there are no previous studies on joint logistics business, this study is meaningful for other studies. Results - As a result of analyzing LPCI presented in this study, the score of logistics enterprise was represented as 59.9 points based on full score of 100 points and that of shippers as 47.2 points and cooperation level among enterprises participated in Joint logistics business was revealed to be very low. In particular, as a result of measuring the importance between logistics enterprise and shippers, the difference by each measurement standard was represented among those enterprises. This difference is considered to be a key factor that cooperative operational conformity between logistics enterprises and shippers is represented to be low. Conclusions - As most joint logistics business, being promoted at present, is sharing facility and information with joint logistics business, it is hard to find such a joint logistics business in reality based on cooperative business model in main cooperation agents. Therefore, competitiveness of logistics industry could be strengthened by promoting joint logistics business based on their mutual cooperation among enterprises. In other words, it is to secure sustainable competitiveness of joint logistics business together with creation of new market by inter-enterprise cooperation based on integration of basic logistics business.

A Study on Usefulness of Clinical Application of Metal Artifact Reduction Algorithm in Radiotherapy (방사선치료 시 Metal artifact reduction Algorithm의 임상적용 유용성평가)

  • Park, Ja Ram;Kim, Min Su;Kim, Jeong Mi;Chung, Hyeon Suk;Lee, Chung Hwan;Back, Geum Mun
    • The Journal of Korean Society for Radiation Therapy
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    • v.29 no.2
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    • pp.9-17
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    • 2017
  • Purpose: The tissue description and electron density indicated by the Computed Tomography(CT) number (also known as Hounsfield Unit) in radiotherapy are important in ensuring the accuracy of CT-based computerized radiotherapy planning. The internal metal implants, however, not only reduce the accuracy of CT number but also introduce uncertainty into tissue description, leading to development of many clinical algorithms for reducing metal artifacts. The purpose of this study was, therefore, to investigate the accuracy and the clinical applicability by analyzing date from SMART MAR (GE) used in our institution. Methode: and material: For assessment of images, the original images were obtained after forming ROIs with identical volumes by using CIRS ED phantom and inserting rods of six tissues and then non-SMART MAR and SMART MAR images were obtained and compared in terms of CT number and SD value. For determination of the difference in dose by the changes in CT number due to metal artifacts, the original images were obtained by forming PTV at two sites of CIRS ED phantom CT images with Computerized Treatment Planning (CTP system), the identical treatment plans were established for non-SMART MAR and SMART MAR images by obtaining unilateral and bilateral titanium insertion images, and mean doses, Homogeneity Index(HI), and Conformity Index(CI) for both PTVs were compared. The absorbed doses at both sites were measured by calculating the dose conversion constant (cCy/nC) from ylinder acrylic phantom, 0.125cc ionchamber, and electrometer and obtaining non-SMART MAR and SMART MAR images from images resulting from insertions of unilateral and bilateral titanium rods, and compared with point doses from CTP. Result: The results of image assessment showed that the CT number of SMART MAR images compared to those of non-SMART MAR images were more close to those of original images, and the SD decreased more in SMART compared to non-SMART ones. The results of dose determinations showed that the mean doses, HI and CI of non-SMART MAR images compared to those of SMART MAR images were more close to those of original images, however the differences did not reach statistical significance. The results of absorbed dose measurement showed that the difference between actual absorbed dose and point dose on CTP in absorbed dose were 2.69 and 3.63 % in non-SMRT MAR images, however decreased to 0.56 and 0.68 %, respectively in SMART MAR images. Conclusion: The application of SMART MAR in CT images from patients with metal implants improved quality of images, being demonstrated by improvement in accuracy of CT number and decrease in SD, therefore it is considered that this method is useful in dose calculation and forming contour between tumor and normal tissues.

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Assessment of the Usefulness of an IMRT Plan Using a Shell-Type Pseudo Target with Patients in Stage III or IV of NSCLC (비소세포폐암 III, IV기 환자에 있어서 Shell-Type Pseudo Target을 이용한 세기 조절 방사선치료계획기법의 유용성 평가)

  • Lee, Sang-Bong;Park, Ki-Ju;Park, Du-Chan;Kim, Man-Wo;Kim, Jun-Gon;Noh, Sung-Hwan
    • The Journal of Korean Society for Radiation Therapy
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    • v.24 no.2
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    • pp.95-106
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    • 2012
  • Purpose: The objective of this study was to investigate the usefulness of an IMRT treatment plan according to whether there was a shell-type pseudo target during radiation therapy for patients in Stage III or IV of non-small cell lung cancer (NSCLC). Materials and Methods: After setting an IMRT (Intensity-Modulated Radiation Therapy, IMRT) plan for when there was a shell-type pseudo target (SPT) and when there was none (WSPT) with 22 patients in Stage III or IV of NSCLC, the investigator analyzed dose-volume histograms (DVHs) and made assessment with dosimetric comparisons such as homogeneity index (HI) inside the tumor target, conformity index (CI) of the tumor target, spinal cord maximum dose, Esophagus $V_{50%}$, mean lung dose (MLD), and $V_{40%}$, $V_{30%}$, $V_{20%}$, $V_{10%}$, $V_{5%}$. Results: The mean CI of WSPT and SPT was $1.22{\pm}0.04$ and $1.16{\pm}0.032$ ($.000^*$), respectively, and the mean HI of WSPT and SPT was $1.06{\pm}0.015$ and $1.07{\pm}0.014$ ($.000^*$), respectively. In SPT, the mean of each CI difference decreased by $-5.16{\pm}2.54%$, while HI increased by average $0.81{\pm}0.47%$. Esophagus $V_{50%}$ recorded $14.54{\pm}12.01%$ (WSPT) and $12.14{\pm}11.09%$ ($.000^*$, SPT) with the mean of SPT differences dropping by $-26.37{\pm}25.05%$. Mean spinal cord maximum dose was $3,898.44{\pm}1,075.0$ cGy (WSPT) and $3,810.8{\pm}1,134.9$ cGy ($.004^*$, SPT) with SPT dropping by average $-3.36{\pm}5.81%$. As for lung $V_{X%}$, the mean of $V_{5%}$ and $V_{10%}$ differences was $-1.62{\pm}2.29%$ ($.006^*$) and $-1.98{\pm}5.02%$ ($.005^*$), respectively with SPT making a decrease. The mean of V20%, V30%, and V40% differences was $-3.51{\pm}3.07%$ ($.000^*$), $-4.84{\pm}6.01%$ ($.000^*$), and $-6.16{\pm}8.46%$ ($.001^*$), respectively, with SPT making a decrease with statistical significance. In MLD assessment, SPT also dropped by average $-2.83{\pm}2.41%$ ($.000^*$). Those results show that SPT allows for mean 169 cGy (Max: 547 cGy, Min: 6.4 cGy) prescription dose. Conclusion: An IMRT treatment plan with SPT during radiation therapy for patients in Stage III or IV of NSCLC will help to reduce the risk of lung toxicity and radiation-induced pneumonia by cutting down radiation doses entering the normal lung, reduce the local control failure rate during radiation therapy due to increasing prescription doses to a certain degree, and increase treatment effects.

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Evaluation of the usefulness of Halcyon VMAT treatment plan through comparison with tomotherapy in bilateral breast cancer radiation therapy. (양측 유방암 방사선치료 시 토모테라피와의 비교를 통한 Halcyon VMAT 치료계획의 유용성 평가)

  • LIM JUN TAEK;PARK JU YOUNG;PARK SU YEON;JEON SEONG JIN;PARK TAE YANG;HWANG DA JIN
    • The Journal of Korean Society for Radiation Therapy
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    • v.34
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    • pp.83-92
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    • 2022
  • Purpose: To evaluate usefulness of Tomotherapy and Halcyon VMAT treatment in radiation therapy for bi-breast cancer Materials and Methods: For 10 patients with bi-breast cancer, volumetric modulated arc therapy(VMAT) treatment plan was established using helical Tomotherapy(Accuray. USA) with field width of 5.0-cm and pitch of 0.287, and Halcyon(Varian Medical System, Palo Alto, CA, Version 3.0 USA) of 6arc and 8arc. Prescribed dose was 42.4 Gy/16, and V 40.3Gy of Planning Target Volume(PTV) was 90%. The quality of plan was evaluated by comparing the dose to tumor and normal organs, and the efficiency was evaluated by comparing total MU and beam on time. Results: About three treatment plans(Tomotherapy, Halcyon 6Arc VMAT, Halcyon 8Arc VMAT) , the mean homogeneity index(H.I) of PTV were 1.07, 1.10, 1.11, and the mean conformity index(C.I) of PTV were 1.21, 1.16, 1.17, respectively. The average value of the dose assessment item for a normal organ is V 5Gy(%) of both lung was 36.3, 31.2, 29.7, and V 15Gy(%) were 18.6, 15.5, 14.6, respectively. The mean heart dose(Gy) were 4.17, 2.69, 2.51. Total MU were (7498.6, 2494.2, 2471.5), and beam on time(sec) were 462.5, 195.4, 198.0. Conclusion: Halcyon VMAT showed similar quality of treatment plan compared to helical Tomotherapy, while also protecting normal organs. In addition, the efficiency of radiotherapy increased due to a decrease in Beam On Time and MU.

Comparison and Evaluation of radiotherapy plans by multi leaf collimator types of Linear accelerator (선형가속기의 다엽콜리메이터 형태에 따른 치료계획 비교 평가)

  • Lim, Ji Hye;Chang, Nam Joon;Seok, Jin Yong;Jung, Yun Ju;Won, Hui Su;Jung, Hae Youn;Choi, Byeong Don
    • The Journal of Korean Society for Radiation Therapy
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    • v.30 no.1_2
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    • pp.129-138
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    • 2018
  • Purpose : An aim of this study was to compare the effect of multi leaf collimator(MLC) types for high dimension radiotherapy in treatment sites used clinically. Material and Method : 70 patients with lung cancer, spine cancer, prostate cancer, whole pelvis, head and neck, breast cancer were included in this study. High definition(HD) MLC of TrueBeam STx (Varian Medical system, Palo Alto, CA) and millenium(M) MLC of VitalBeam (Varian Medical system, Palo Alto, CA) were used. Radiotherapy plans were performed for each patient under same treatment goals with Eclipse (Version 13.7, Varian Palo Alto USA, CA). To compare the indicators of the radiotherapy plans, planning target volume(PTV) coverage, conformity index(CI), homogeneity index(HI), and clinical indicators for each treatment sites in normal tissues were evaluated. To evaluate low dose distribution, $V_{30%}$ values were compared according to MLC types. Additionally, length and volume of targets for each treatment sites were investigated. Result : In stereotatictic body radiotherapy(SBRT) plan for lung, the average value of PTV coverage was reduced by 0.52 % with HD MLC. With SBRT plan using HD MLC for spine, the average value of PTV coverage decreased by 0.63 % and maximum dose decreased by 1.13 %. In the test of CI and HI, the values in SBRT plan with HD MLC for spine were 1.144, 1.079 and the values using M MLC were 1.160, 1.092 in SBRT plan for lung, The dose evaluation of critical organ was reduced by 1.48 % in the ipsilateral lung mean dose with HD MLC. In prostate cancer volumetric modulated arc therapy(VMAT) with HD MLC, the mean dose and the $V_{30}$ of bladder and the mean dose and the $V_{25}$ of rectum were reduced by 0.53 %, 1.42 %, 0.97 %, and 0.69 %, respectively (p<0.05). The average value of heart mean dose was reduced by 0.83 % in breast cancer VMAT with M MLC. Other assessment indices for treatment sites showed no significant difference between treatment plans with two types of MLC. Conclusion : Using HD MLC had a positive impact on the PTV coverage and normal tissue sparing in usually short or small targets such as lung and spine SBRT and prostate VMAT. But, there was no significant difference in targets with long and large such as lung, head and neck, and whole pelvis for VMAT.

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