• Title/Summary/Keyword: Zinc Effect

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Effects of Cadmium and Zinc on Plasma ACTH and Serum Cortisol Levels in Rats (카드뮴 및 아연이 백서 혈장 ACTH 및 혈청 Cortisol에 미치는 영향)

  • 김주영
    • Journal of environmental and Sanitary engineering
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    • v.12 no.2
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    • pp.37-42
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    • 1997
  • The toxic and detoxifying effects of cadmium and zinc on rat plasma ACTH and serum cortisol levels were investigated in rats. Rats were injected by i.p. with saline (0.9%), cadmium chloride (0.25 or 0.5mg/kg body weight) and pretreated with zinc chloride (4mg/kg body weight) before cadmium chloride treatment 1 or 2 weeks, respectively. The ACTH levels were no significant differences in cadmium 0.25mg/kg-treated group, but were significantly decreased in cadmium 0.5mg/kg-treated group compared with normal group. The ACTH levels after zinc pretreatment for 1 week were significantly increased but zinc pretreatment for 2 week were no difference. The serum cortisol levels of cadmium treated rats were significantly decreased, but were increased in zinc pretreated rats. The results showed that the zinc have some protective effect on cadmium toxicity in rats.

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Effect of the electrolyte composition and the plating condition on the hardness of zinc deposit in the sulfate bath (황산아연욕에서 도금층 경도에 미치는 욕조성 및 도금조건의 영향)

  • 김명수;김영근
    • Journal of the Korean institute of surface engineering
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    • v.33 no.5
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    • pp.356-364
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    • 2000
  • Factors that affect the hardness of the zinc electrodeposits in the sulfate electrolyte were investigated. The hardness of zinc deposit was enhanced by increasing the concentration of impurities such as iron and nickel in the bath that changed the crystallographic orientation of the zinc deposit from the strong basal plane to the random orientation. The increase of the concentration of sodium sulfate and current density in iron contained bath improved the hardness of zinc deposit because those were easily codeposited in zinc layer. However the increase of the concentration of sodium sulfate up to 80g/$\ell$ in the bath darkened the surface of zinc electrodeposits due to change of morphology by the codeposition of iron.

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Effect of Zinc Based Anodes on Self-Discharge Behavior for Zinc-Air Batteries (아연-공기 전지용 음극재의 자가방전 억제 효과)

  • Jung, Min Seo;Jo, Yong Nam
    • Korean Journal of Materials Research
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    • v.30 no.12
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    • pp.709-714
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    • 2020
  • For zinc-air batteries, there are several limitations associated with zinc anodes. The self-discharge behavior of zinc-air batteries is a critical issue that is induced by corrosion reaction and hydrogen evolution reaction (HER) of zinc anodes. Aluminum and indium are effective additives for controlling the hydrogen evolution reaction as well as the corrosion reaction. To enhance the electrochemical performances of zinc-air batteries, mechanically alloyed Zn-Al and Zn-In materials with different compositions are successfully fabricated at 500rpm and 5h milling time. Investigated materials are characterized by X-ray diffractometer (XRD), field emission scanning electron microscope (FE-SEM), and energy dispersive spectrometer (EDS). Alloys are investigated for the application as novel anodes in zinc-air batteries. Especially, the material with 3 wt% of indium (ZI3) delivers 445.37 mAh/g and 408.52 mAh/g of specific discharge capacity with 1 h and 6 h storage, respectively. Also, it shows 91.72 % capacity retention and has the lowest value of corrosion current density among attempted materials.

Zinc status and growth of Korean infants fed human milk, casein-based, or soy-based formula: three-year longitudinal study

  • Han, Young-Hee;Yon, Mi-Yong;Han, Heon-Seok;Johnston, Kelley E.;Tamura, Tsunenobu;Hyun, Tai-Sun
    • Nutrition Research and Practice
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    • v.5 no.1
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    • pp.46-51
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    • 2011
  • To evaluate the effect of feeding methods on growth and zinc nutritional status of infants early in life, we monitored from birth to 36 months in 51 infants who were exclusively fed human milk (HM, n=20), casein-based formula (CBF, n=12), or soy-based formula (SBF, n=19) during the first five months of life. Zinc status was assessed by analyzing serum zinc concentrations and zinc intakes. Zinc contents in HM and formulas were measured. Zinc intake was estimated by weighing infants before and after feeding in the HM group and by collecting formula-intake records in the CBF and SBF groups. After solid foods were introduced, all foods consumed were also included to estimate zinc intake. The growth of infants in all groups was similar to that established for normal Korean infants. Human milk zinc concentrations declined as lactation progressed. Zinc concentrations in all formulas tested in this study were higher than HM and were also higher than those claimed by the manufacturers. During the first twelve months, mean serum zinc concentrations of infants were similar in all groups, although infants in the HM group consistently had the lowest zinc intake among the groups, and the overall zinc intake in infants fed SBF was highest. This finding could be explained by the difference zinc bioavailability of HM and formulas. In conclusion, infants fed HM, CBF or SBF has normal growth up to three years of age, although HM contained the lowest zinc concentration followed by CBF, then SBF.

Effect of Sodium Selenite and Zinc-L-selenomethionine on Performance and Selenium Concentrations in Eggs of Laying Hens

  • Chantiratikul, Anut;Chinrasri, Orawan;Chantiratikul, Piyanete
    • Asian-Australasian Journal of Animal Sciences
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    • v.21 no.7
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    • pp.1048-1052
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    • 2008
  • The objective of this study was to determine the effect of sodium selenite and zinc-L-selenomethionine on performance and egg Se concentration in laying hens. Two hundred and twenty-four CP Browns aged 71 weeks were divided according to a $2{\times}3$ factorial in a completely randomized design. One more group without additional Se supplementation was used as a negative control. Each treatment consisted of four replicates and each replicate contained eight laying hens. The dietary treatments were T1: basal diet; T2, T3 and T4: basal diets plus 0.3, 1.0 and 3.0 mg Se from sodium selenite/kg, respectively; T5, T6 and T7: basal diets plus 0.3, 1.0 and 3.0 mg Se from zinc-L-selenomethionine/kg, respectively. The findings revealed that feed conversion rate/kg eggs, egg production, egg weight, Haugh units and eggshell thickness were not affected by source and level of Se (p>0.05). Increasing level of dietary Se significantly increased (p<0.05 the Se content of eggs. Zinc-L-selenomethionine markedly increased p<0.05 egg Se concentration as compared with sodium selenite. The results indicated that Se source did not influence performance of laying hens. However, zinc-L-selenomethionine increased p<0.05 egg Se concentration more than sodium selenite.

Effect of Different Dietary Zinc and Protein Levels on Lipid Metabolism (식이 중 아연과 단백질의 수준이 성숙쥐의 지질대사에 미치는 영향)

  • 정명일
    • Journal of Nutrition and Health
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    • v.22 no.1
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    • pp.9-22
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    • 1989
  • The effect of different levels of Zn (0, 30, 300ppm) and protein(7, 20, 40%) in the diet upon lipid metabolism was investigated in Sprague-Dawley male rats weighting 180.54$\pm$29.08g(n=450 fed one of nine diets in a 3$\times$3 factorial design for 5 weeks. The reults obtained were summarized as following. 1) Total lipid contents in serum and liver were tended to be lower in LZn group than CZn and Hzn groups. Those of LP group were higher than CP and HP groups. 2) HDL-cholesterol and total cholesterol contents in serum were significantly affected by dietary Zinc level and were increased as dietary Zinc level increase. 3) Total cholesterol in liver and muscle were tended to be decrease as dietary Zinc level increase. Those in LP group were higher than CP and HP groups. 4) Zinc contents in plasma, liver, muscle and testis were tended to be lower in LZn group than CZn and HZn groups. 5) Protein contents in plasma and liver lower in LZn group than CZn and HZn groups when dietary protein level was 7% and 20%. Those in LP group were lower than those in CP and HP groups. 6) Cu contents in plasma, liver, muscle and testis were tended to be decreased as dietary Zinc level increase.

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Effect of Al Addition on the Reaction Behavior of Pure Cobalt with Molten Zinc (용융 아연과 WC-Co 코팅층 내 코발트의 반응거동에 미치는 아연욕 중의 Al 첨가 영향)

  • Seong, Byeong-Geun;Kim, Kyoo-Young;Kwon, Sung-Hee;Lee, Kee-Ahn
    • Journal of the Korean institute of surface engineering
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    • v.40 no.1
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    • pp.23-31
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    • 2007
  • The objective of this study is to investigate the effect of Al addition on the reaction behavior of cobalt with molten zinc. Pure cobalt specimen was immersion tested in the three kinds of molten zinc (pure, 0.12%Al added and 0.24%Al added) baths at $460^{\circ}C,\;490^{\circ}C\;and\;520^{\circ}C$. For the understanding of degradation processes, specimens were analyzed with scanning electron microscope (SEM) and energy dispersive spectrum (EDS), and electrochemical stripping method. When 0.12% and 0.24% Al was added in molten zinc baths, three intermetallic compounds layers of ${\gamma},\;{\gamma}_1,\;and\;{\gamma}_2$ were formed on the Co matrix and ${\beta}_1$ layer was not formed between the Co matrix and the ${\gamma}$ layer. Particles of CoAl intermetallic compound were formed at the interface between the ${\gamma}_2$ layer and zinc melt and they did not adhere to the Co-Zn intermetallic layer. Weight loss of the Co specimen increased as Al content in the molten zinc increased and the relationship of weight loss vs. immersion time followed parabolic rate law. Rate controlling process for the reaction rate of Co with Al added molten zinc was analyzed as the diffusion process of Al atom through a boundary layer between the ${\gamma}_2$ layer and the Al added zinc melt.

Effect of zinc on the immune response and production performance of broilers: a meta-analysis

  • Hidayat, Cecep;Sumiati, Sumiati;Jayanegara, Anuraga;Wina, Elizabeth
    • Asian-Australasian Journal of Animal Sciences
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    • v.33 no.3
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    • pp.465-479
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    • 2020
  • Objective: This study performed a meta-analysis of published trials to determine the effects of zinc on the immune response and production performance of broilers. Methods: A database was built from published literature regarding the addition of zinc forms or doses and their relation to the immune response and production performance of broilers. Different doses or forms of zinc were identified in the database. The recorded parameters were related to the immune response and production performance. The database contained a total of 323 data points from 41 studies that met the criteria. Then, the data were processed for a meta-analysis using a mixed model methodology. The doses or different forms of zinc were considered fixed effects, different studies were treated as random effects, and p-values were used as the model statistics. Results: An increase in zinc dose increased (p<0.05) pancreas metallothionein (MT) and zinc concentrations in the plasma, tibia and meat, all in quadratic patterns, but linearly decreased (p<0.05) the heterophil/lymphocyte (H/L) ratio. Regarding the different zinc forms, both inorganic and organic zinc increased (p<0.05) the zinc concentrations in the plasma and tibia, the calcium and phosphorus contents in the tibia, and the antioxidant activity of superoxide dismutase in meat as compared to control. An increase in zinc dose increased average daily gain (ADG) and decreased feed conversion ratio (FCR) following a quadratic pattern (p<0.05). Inorganic and organic zinc decreased (p<0.05) FCR and H/L ratio than that of control, but these two forms were similar for these parameters. Conclusion: Zinc addition has a positive impact on immunity and broiler production. Zinc can suppress stress and inhibit the occurrence of lipid peroxidation in broilers, and it can also improve ADG, FCR, and the quality of broiler carcasses.

Cytoprotective Effect of Zinc-Mediated Antioxidant Gene Expression on Cortisol-Induced Cytotoxicity (Cortisol 유발 세포독성에 대한 아연 관련 항산화 유전자 발현 증가에 의한 세포보호 효과)

  • Chung, Mi Ja;Kim, Sung Hyun;Hwang, In Min
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.44 no.5
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    • pp.649-656
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    • 2015
  • The protective effect of zinc against cortisol-induced cell injury was examined in rainbow trout gill epithelial cells. Cells exposed to cortisol for 24 h showed increased leakage of lactate dehydrogenase (LDH) as well as decreased cell viability in a dose-dependent manner. Treatment with zinc ($100{\mu}M$ $ZnSO_4$) reduced the severity of both LDH release and cell death as well as protected cells against cortisol-induced caspase-3 activation, indicating reduction of apoptosis. Cortisol-induced cell death, leakage of LDH, and caspase-3 activation were blocked by the glucocorticoid receptor antagonist Mifepristone (RU-486), suggesting that cell injury was cortisol-dependent. In addition, we studied the effect of zinc on the expression of antioxidant genes such as metallothionein A (MTA), metallothionein B (MTB), glutathione-S-transferase (GST), and glucose-6-phosphate dehydrogenase (G6PD) during cortisol-induced cell injury. MTA, MTB, GST, and G6PD mRNA levels increased after treatment with zinc or cortisol, separately or in combination. Higher mRNA levels of MTA, MTB, GST, and G6PD were detected when cells were treated with $100{\mu}M$ $ZnSO_4$ and $1{\mu}M$ cortisol in combination at the same time compared to treatment with zinc or cortisol separately. Cells treated with zinc showed increased intracellular free zinc concentrations, and this response was significantly enhanced in cells treated with cortisol and zinc. In conclusion, zinc treatment inhibited cortisol-induced cytotoxicity and apoptosis through indirect antioxidant action.

Preparation of Zinc Oxide by Hydrothermal Precipitation Method and their Photocatalytic Characterization (수열합성법에 의한 산화아연의 제조와 광분해 특성)

  • Jeong, Sang-Gu;Na, Seok-Eun;Kim, Si-Young;Ju, Chang-Sik
    • Korean Chemical Engineering Research
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    • v.50 no.5
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    • pp.808-814
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    • 2012
  • Photocatalytic zinc oxide powders were prepared from precursor zinc acetate and ammonia solution at elevated temperature, $80^{\circ}C$, by hydrothermal precipitation method. The effect of operating parameters, pH of ammonia solution and concentration of zinc acetate solution, on the characteristics of zinc oxide powders were experimentally examined. Zinc oxide powders prepared at the conditions of pH 11, zinc acetate concentration of 1.0 M, precipitation temperature of $80^{\circ}C$, showed smallest average particle diameter of $3{\mu}m$. SEM and XRD analysis confirmed that prepared zinc oxide has hexagonal rods structure, and Anatase type crystallinity. In addition, DRS and PL analysis showed that the zinc oxide has activity at the range of 200~400 nm of UV light. And the zinc oxide decomposed 57% of a food-color stamp Brilliant blue FCF for 3 hours under the UV radiation.