• Bulletin of the Korean Chemical Society
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• 제31권7호
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• pp.1881-1886
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• 2010

Hydrothermal reaction of zinc(II) salts with 5-sulfoisophthalic acid monosodium salt ($NaO_3SC_6H_3$-1,3-(COOH)$_2$, $NaH_2$-SIP) and 1,10-phenanthroline (phen) led to two new compounds, [Zn(phen)$_3$$\cdot2H_2SIP\cdot4H_2O$ (1) and [Zn(phen)$_2(H_2O)_2]\cdot2H_2SIP\cdot2H_2O$ (2). They were characterized by element analysis, IR spectroscopy, thermalgravimetric analysis (TGA), X-ray powder diffraction (XRD), and single-crystal X-ray diffraction. Both compounds 1-2 represent the first example of Zn/phen/SIP system. The Zn (II) ion in 1 is six-coordinated by six nitrogen atoms from three phen molecules, and the $H_2SIP^-$ ligands engage in the formation of hydrogen bond. The Zn(II) ion in 2 is coordinated by four nitrogen atoms from two phen molecules and two oxygen atoms from two water molecules. Moreover, both 1 and 2 are assembled into 3D supramolecular architectures by hydrogen bonds (O-H$\ldots$O) and $\pi-\pi$ interactions. Solvent water molecules occupying voids of the compounds serve as receptors or donors of the extensive O-H$\ldots$O hydrogen bonds.

• 한국염색가공학회지
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• 제23권3호
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• pp.163-168
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• 2011

In this article, we synthesized an azo dye rotaxane containing bis(8-hydroxyquinoline) group and its polymeric metal complex with zinc. The azo dye rotaxane exhibits high pH sensitivity, solvatochromism and zinc (II) ion sensings in aqueous solution. These behaviors came from the tautomeric equilibrium between azo-hydrazone tautomers and the formation of extended conjugation. The structure of polymeric zinc complexed dye rotaxane was confirmed with NMR and FT-IR measurements. The existence of CD rings, provided by dye rotaxane formation, was found to be very beneficial in improving aqueous solubility of polymeric metal complex.

• 분석과학
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• 제6권1호
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• pp.131-139
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• 1993

아연광 중 미량으로 존재하는 갈륨 및 인듐을 유도결합 플라스마 원자방출분광법(ICP-AES)으로 분석할 때 간섭하는 아연 및 다른 이온들과 특히 Fe(III) 이온으로부터 이들을 분리하는 방법에 대해 연구하였다. 갈륨과 인듐을 tributyl phosphate(TBP)로 용매추출하였는데 이때 영향을 주는 산농도, 다른 이온들의 간섭, 수용액상/유기상의 비율, TBP의 농도 및 탈거율 등에 대하여 조사하였다. 갈륨과 인듐이 함유되어 있는 아연광을 녹인 5N 염산용액에서 100% TBP로 추출하여 아연 및 기타 간섭이온들로부터 분리하였으며, 이때 철(III)이온은 hydroxylamine hydrochloride를 사용하여 Fe(II)로 환원시켜 coetraction되는 것을 방지하였다. 유기상으로부터 갈륨과 인듐의 탈거는 0.02N 염산용액으로 역추출하여 이루어졌으며 이 용액을 ICP-AES로 측정하여 이들을 정량하였다. 전체적으로 추출률이 95% 이상으로 정량적이었다.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.149.3-150
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• 2003

CYP3A4 is the most abundant human CYP and oxidizes a diversity of substrates. including various drugs. steroids. and carcinogens. A variety of metal ions are known to affect microsomal monooxygenase activities. Effects of a series of divalent metal ions on the CYP3A4-catalyzed reaction of reconstituted system containing purified CYP3A4. NADPH-P450 reductase (NPR), and cytochrome b5 (b5) were examined. (omitted)

• 대한화학회지
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• 제62권1호
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• pp.14-18
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• 2018

The complexes $[Zn(L)(H_2O)_2]{\cdot}2NO_2$ (1) and $[Zn(L)(NO_3)_2]$ (2) (L = 3,14-dimethyl-2,6,13,17-tetraazatricyclo $[14,4,0^{1.18},0^{7.12}]$docosane) have been synthesized and structurally characterized. The compound 1 crystallizes in the monoclinic system $P2_1/c$ with a = 8.74650(10), b = 18.6880(3), c = $7.96680(10){\AA}$, ${\beta}=109.1920(10)^{\circ}$, $V=1229.84(3){\AA}^3$, Z = 2. The compound 2 crystallizes in the monoclinic system P1 with a = 8.1292(5), b = 8.9244(5), c = $9.1398(5){\AA}$, ${\alpha}=68.035(2)$, ${\beta}=70.109(2)$, ${\gamma}=75.649(3)^{\circ}$, $V=572.70(6){\AA}^3$, Z = 1. The crystal structures of the compounds 1 and 2 show a distorted octahedral coordination geometry around the zinc(II) ion, with four secondary amines and two oxygen atoms of the two water and two nitrate ligands at the axial position. The TGA behaviors of the complexes are significantly affected by the nature of the tetraaza macrocycle and the axial ligands.

• Bulletin of the Korean Chemical Society
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• 제31권10호
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• pp.2923-2928
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• 2010

This study examined the synthesis of the crystal structure of bis(2,2'-bipyridine)nitrato zinc (II) nitrate, $[Zn(bipy)_2(NO_3)]^+NO_3^-$ using a microwave treatment at 300 W and 60 Hz for the application to dye-sensitized solar cells. The simulated complex structure of the complex was optimized with the density functional theory calculations for the UV-vis spectrum of the ground state using Gaussian 03 at the B3LYP/LANL2DZ level. The structure of the acquired complex was expected a penta-coordination with four nitrogen atoms of bipyridine and the oxygen bond of the $NO_3^-$ ion. The reflectance UV-vis absorption spectra exhibited two absorptions (L-L transfers) that were assigned to the transfers from the ligand ($\sigma$, $\pi$) of $NO_3$ to the ligand ($\sigma^*$, $\pi^*$) of pyridine at around 200 - 350 nm, and from the non-bonding orbital (n) of O in $NO_3$ to the p-orbital of pyridine at around 450 - 550 nm, respectively. The photoelectric efficiency was approximately 0.397% in the dye-sensitized solar cells with the nanometer-sized $TiO_2$ at an open-circuit voltage (Voc) of 0.39 V, a short-circuit current density (Jsc) of $1.79\;mA/cm^2$, and an incident light intensity of $100\;mW/cm^2$.

• Bulletin of the Korean Chemical Society
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• 제34권5호
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• pp.1487-1493
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• 2013

Based on the finding that the 2-aminobenzamido group of MS-275 plays a crucial role in inhibiting HDACs through chelation of zinc existing at the active site of HDAC enzymes, novel N-(2-hydroxyphenyl)arylsulfonamide derivatives were synthesized for their potential ability to inhibit HDACs and evaluated for anticancer activity against human breast cancer cell line (MCF-7). Although the synthesized arylsulfonamides have failed to significantly inhibit total HDACs activity, phenyl carbamate-linked arylsulfonamide 10 and benzyl thiocarbamate-linked arylsulfonamide 15 exhibited good anticancer activities, which were only 4.3- and 3.6-fold lower anticancer activities, respectively, than MS-275 that is undergoing phase II clinical trials. These results suggest that these compounds may act as a selective HDAC inhibitor and probably N-(2-hydroxyphenyl) sulfamoyl group may play an important role in interacting with HDAC enzymes through chelation of zinc ion.

• 대한화학회지
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• 제32권1호
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• pp.30-36
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• 1988

에틸렌디아민, 프로필렌디아민 및 디에틸렌트리아민의 구리(II), 카드뮴(II) 및 아연(II) 착이온의 安定度에 미치는 壓力의 影響을 폴라로그래피로 조사하였다. 支持電解質로서는 0.10M의 KN$O_3$ 용액을 쓰고, 킬레이트제의 농도는 0.01M에서 0.1M까지 변화시켰다. 압력이 1기압에서 1,500기압으로 증가함에 따라 금속착이온의 解離常數는 증가하였으며, 단위압력당 증가율은 $Cu(dien)_2^{2+}$의 1.1 ${\times} 10^{-3}$ %에서 Zn(en)$_2^{2+}$의 5.0${\times} 10^{-3}$ % 까지의 값으로 나타났다.

• 통합자연과학논문집
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• 제7권2호
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• pp.130-137
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• 2014

Resins were synthesized by mixing N-phenylaza-15-crown-5 macrocyclic ligand attached to styrene (2th petroleum in 4th class hazardous materials) divinylbenzene (DVB) copolymer with crosslink of 1%, 2%, 6%, and 12% by substitution reaction. The synthesis of these resins was confirmed by content of chlorine, element analysis, thermo gravimetric analysis (TGA), surface area, and IR-spectroscopy. The effects of pH, equilibrium arrival time, dielectric constant of solvent and crosslink on adsorption of metal ions by the synthetic resin adsorbent were investigated. The metal ions were showed fast adsorption on the resins above pH 4. The optimum equilibrium time for adsorption of metallic ions was about two hours. The adsorption selectivity determined in ethanol was in increasing order uranium (VI) > zinc (II) > europium (III) ions. The uranium ion adsorbed in the order of 1%, 2%, 6%, and 12% crosslink resin and adsorption of resin decreased in proportion to the order of dielectric constant of solvents.

• 자원리싸이클링
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• 제2권4호
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• pp.27-32
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• 1993

제강더스트 중에 미량으로 함유되어 있는 갈륨을 분리 회수하는 프로세스를 연구하였다. 2.25mol/l-$H_2SO_4$ 침출에의하여 38mg/l의 갈륨을 함유하는 수용액을 얻었다. 이 침출액 중에서 1000배 량의 철과 아연이 함유되어 있다. 침출액 중의 갈륨은 철(III)이온을 철(II)이온으로 환원하고, pH 조정한 후, 아미노카르본산형 관능기를 가진 킬레이트 수지를 이용하여 흡착 농축하였다. 1.5mol/l-$H_2SO_4$에 의한 용리액을 칼럼에 재공급하고 재농축하여, 3.0mol/l-HCl을 이용하여 용리하였다. 용리액 중의 갈륨은 13g/l의 농도를 나타내었다. 갈륨의 정제는 용매추출법에 의하여 정제하였다. 추출제로는 TOMAC(tri-n-octhylmethylammonium chloride)을 사용하여 순수한 갈륨 정제액을 얻었다.