• Title/Summary/Keyword: Zhengzhou

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Clinical Applicability of Multi-Tumor Marker Protein Chips for Diagnosing Ovarian Cancer

  • Bian, Jing;Li, Bo;Kou, Xian-Juan;Wang, Xu-Na;Sun, Xiao-Xu;Ming, Liang
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.19
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    • pp.8409-8411
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    • 2014
  • Purpose: To assess the value of multi-tumor marker protein chips in the diagnosis and treatment of ovarian cancer. Materials and Methods: Twelve tumor markers (CA19-9, NSE, CEA, CA242, CK19, ${\beta}$-HCG, AFP, SCC, c-PSA, CA125, CA724 and CA15-3) were detected by protein biochip in 220 patients with ovarian carcinomas, 205 with benign ovarian tumors and 200 healthy subjects. Results: The positivity rate was obviously higher in ovarian cancer (77.7%), than that in the benign cases (26.3%, p<0.01) and healthy subjects (4.5%, p<0.01). Serum levels of tumor markers were furthermore significantly higher in cases with lymph node metastasis (86.8%) than those without metastasis (44.7%), p<0.01. Conclusions: Multi-tumor marker protein chips provide important assistance in the diagnosis and treatment evaluation in ovarian cancers.

A Human Case of Zoonotic Dog Tapeworm, Dipylidium caninum (Eucestoda: Dilepidiidae), in China

  • Jiang, Peng;Zhang, Xi;Liu, Ruo Dan;Wang, Zhong Quan;Cui, Jing
    • Parasites, Hosts and Diseases
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    • v.55 no.1
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    • pp.61-64
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    • 2017
  • We described a human case of zoonotic dog tapeworm, Dipylidium caninum (Eucestoda: Dilepidiidae), rarely occurring in China. The mother of a 17 month-old boy noted the appearance of small white and active worms over a month period in her son's feces, but the boy was asymptomatic except mild diarrhea. We observed 3 tapeworm proglottids resembling cucumber seeds in his stool sample. Microscopically, each proglottid had 2 genital pores, 1 on each lateral edge, and numerous egg capsules in the uterus. The patient was successfully treated with a single oral dose of praziquantel. Adult worms were recovered in the diarrheic stool after praziquantel treatment and purgation. His family had household pet dogs for several years, and he might have acquired the infection by ingestion of infected fleas of his pet dogs. A history of dog or cat pets and flea bites may be important clues to diagnosis of D. caninum infection. The infected pets should also be treated.

Functional Analysis of B7-H3 in Colonic Carcinoma Cells

  • Lu, Peng;Liu, Rong;Ma, Er-Min;Yang, Tie-Jian;Liu, Jia-Lin
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.8
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    • pp.3899-3903
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    • 2012
  • B7-H3 is a newly discovered member of the B7/CD28 superfamily which functions as an important T-cell immune molecule. It has been reported recently that B7-H3 is highly expressed in many cancer cells, the data indicating that it may be a regulation factor contributing to tumor-resistance. In our study, we used bioinformatics to identify differentially expressed genes between colonic cancer cells and normal colonic cells, aiming to analyze mechanisms and identify sub-pathways closely related to progression, with the final aim of finding small molecule drugs which might interfere this progression. We found that ajmaline is one related factor which may enhance self-immunity in colon carcinoma therapy and B7-H3 plays important roles with regard to immunoreactions of colonic cancer cells. All the results indicate that H7-B3 is a favorable prognostic biomarker for colon carcinomas, providing novel information regarding likely targets for intervention.

Tensor-Based Channel Estimation Approach for One-Way Multi-Hop Relaying Communications

  • Li, Shuangzhi;Mu, Xiaomin;Guo, Xin;Yang, Jing;Zhang, Jiankang
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.9 no.12
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    • pp.4967-4986
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    • 2015
  • Multi-hop relaying communications have great potentials in improving transmission performance by deploying relay nodes. The benefit is critically dependent on the accuracy of the channel state information (CSI) of all the transmitting links. However, the CSI has to be estimated. In this paper, we investigate the channel estimation problem in one-way multi-hop MIMO amplify-and-forward (AF) relay system, where both the two-hop and three-hop communication link exist. Traditional point-to-point MIMO channel estimation methods will result in error propagation in estimating relay links, and separately tackling the channel estimation issue of each link will lose the gain as part of channel matrices involved in multiple communication links. In order to exploit all the available gains, we develop a novel channel estimation model by structuring different communication links using the PARAFAC and PARATUCK2 tensor analysis. Furthermore, a two-stage fitting algorithm is derived to estimate all the channel matrices involved in the communication process. In particular, essential uniqueness is further discussed. Simulation results demonstrate the advantage and effectiveness of the proposed channel estimator.

A new visual tracking approach based on salp swarm algorithm for abrupt motion tracking

  • Zhang, Huanlong;Liu, JunFeng;Nie, Zhicheng;Zhang, Jie;Zhang, Jianwei
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.14 no.3
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    • pp.1142-1166
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    • 2020
  • Salp Swarm Algorithm (SSA) is a new nature-inspired swarm optimization algorithm that mimics the swarming behavior of salps navigating and foraging in the oceans. SSA has been proved to enable to avoid local optima and enhance convergence speed benefiting from the adaptive nonlinear mechanism and salp chains. In this paper, visual tracking is considered to be a process of locating the optimal position through the interaction between leaders and followers in successive images. A novel SSA-based tracking framework is proposed and the analysis and adjustment of parameters are discussed experimentally. Besides, the qualitative analysis and quantitative analysis are performed to demonstrate the tracking effect of our proposed approach by comparing with ten classical tracking algorithms. Extensive comparative experimental results show that our algorithm has good performance in visual tracking, especially for abrupt motion tracking.

Modeling, Dynamic Analysis and Control Design of Full-Bridge LLC Resonant Converters with Sliding-Mode and PI Control Scheme

  • Zheng, Kai;Zhang, Guodong;Zhou, Dongfang;Li, Jianbing;Yin, Shaofeng
    • Journal of Power Electronics
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    • v.18 no.3
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    • pp.766-777
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    • 2018
  • In this paper, a sliding mode and proportional plus integral (SM-PI) control combined with self-sustained phase shift modulation (SSPSM) for LLC resonant converters is presented. The proposed control scheme improves the transient response while preserving good steady-state performance. An averaged large signal model of an LLC converter with the ZVS modulation technique is developed for the SM control design. The sliding surface is obtained based on the input-output linearization concept. A system identification method is adopted to obtain the transform function of the LLC resonant converter, which is used to design the PI control. In order to reduce the inherent chattering problem in the steady state, the combined SM-PI control strategy is derived with fuzzy control, where the SM control is responsive during the transient state while the PI control prevails in the steady state. The combination of SSPSM and the SM-PI control provides ZVS operation, robustness and a fast transient response against step load variations. Simulation and experimental results validate the theoretical analysis and the attractive features of the proposed scheme.

A City-Level Boundary Nodes Identification Algorithm Based on Bidirectional Approaching

  • Tao, Zhiyuan;Liu, Fenlin;Liu, Yan;Luo, Xiangyang
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.15 no.8
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    • pp.2764-2782
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    • 2021
  • Existing city-level boundary nodes identification methods need to locate all IP addresses on the path to differentiate which IP is the boundary node. However, these methods are susceptible to time-delay, the accuracy of location information and other factors, and the resource consumption of locating all IPes is tremendous. To improve the recognition rate and reduce the locating cost, this paper proposes an algorithm for city-level boundary node identification based on bidirectional approaching. Different from the existing methods based on time-delay information and location results, the proposed algorithm uses topological analysis to construct a set of candidate boundary nodes and then identifies the boundary nodes. The proposed algorithm can identify the boundary of the target city network without high-precision location information and dramatically reduces resource consumption compared with the traditional algorithm. Meanwhile, it can label some errors in the existing IP address database. Based on 45,182,326 measurement results from Zhengzhou, Chengdu and Hangzhou in China and New York, Los Angeles and Dallas in the United States, the experimental results show that: The algorithm can accurately identify the city boundary nodes using only 20.33% location resources, and more than 80.29% of the boundary nodes can be mined with a precision of more than 70.73%.

Transiting test method for galloping of iced conductor using wind generated by a moving vehicle

  • Guo, Pan;Wang, Dongwei;Li, Shengli;Liu, Lulu;Wang, Xidong
    • Wind and Structures
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    • v.28 no.3
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    • pp.155-170
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    • 2019
  • This paper presents a novel test method for the galloping of iced conductor using wind generated by a moving vehicle which can produce relative wind field. The theoretical formula of transiting test is developed based on theoretical derivation and field test. The test devices of transiting test method for aerodynamic coefficient and galloping of an iced conductor are designed and assembled, respectively. The test method is then used to measure the aerodynamic coefficient and galloping of iced conductor which has been performed in the relevant literatures. Experimental results reveal that the theoretical formula of transiting test method for aerodynamic coefficient of iced conductor is accurate. Moreover, the driving wind speed measured by Pitot tube pressure sensors, as well as the lift and drag forces measured by dynamometer in the transiting test are stable and accurate. Vehicle vibration slightly influences the aerodynamic coefficients of the transiting test during driving in ideal conditions. Results of transiting test show that the tendencies of the aerodynamic coefficient curve are generally consistent with those of the wind tunnel tests in related studies. Meanwhile, the galloping is fairly consistent with that obtained through the wind tunnel test in the related literature. These studies validate the feasibility and effectiveness of the transiting test method. The present study on the transiting test method provides a novel testing method for research on the wind-resistance of iced conductor.

Incremental Strategy-based Residual Regression Networks for Node Localization in Wireless Sensor Networks

  • Zou, Dongyao;Sun, Guohao;Li, Zhigang;Xi, Guangyong;Wang, Liping
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.16 no.8
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    • pp.2627-2647
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    • 2022
  • The easy scalability and low cost of range-free localization algorithms have led to their wide attention and application in node localization of wireless sensor networks. However, the existing range-free localization algorithms still have problems, such as large cumulative errors and poor localization performance. To solve these problems, an incremental strategy-based residual regression network is proposed for node localization in wireless sensor networks. The algorithm predicts the coordinates of the nodes to be solved by building a deep learning model and fine-tunes the prediction results by regression based on the intersection of the communication range between the predicted and real coordinates and the loss function, which improves the localization performance of the algorithm. Moreover, a correction scheme is proposed to correct the augmented data in the incremental strategy, which reduces the cumulative error generated during the algorithm localization. The analysis through simulation experiments demonstrates that our proposed algorithm has strong robustness and has obvious advantages in localization performance compared with other algorithms.

Experimental study on the horizontal bearing characteristics of long-short-pile composite foundation

  • Chen-yu Lv;Yuan-cheng Guo;Yong-hui Li;An-di Hu-yan;Wen-min Yao
    • Geomechanics and Engineering
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    • v.33 no.4
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    • pp.341-352
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    • 2023
  • Long-short pile composite foundations bear both vertical and horizontal loads in many engineering applications. This study used indoor model tests to determine the horizontal bearing mechanism of a composite foundation with long and short piles under horizontal loads. A custom experimental device was developed to prevent excessive eccentricity of the vertical loading device caused by the horizontal displacement. ABAQUS software was used to analyze the influence of the load size and cushion thickness on the horizontal bearing mechanism. The results reveal that a large vertical load leads to soil densification and increases the horizontal bearing capacity of the composite foundation. The magnitude of the horizontal displacement of the pile and the horizontal load borne by the pile are related to the piles' positions. Due to different pile lengths, the long piles exhibit long pile effects and experience bending deformation, whereas the short piles rotate around a point (0.2 L from the pile bottom) as the horizontal load increases. Selecting a larger cushion thickness significantly improves the horizontal load sharing capacity of the soil and reduces the horizontal displacement of the pile top.