• Journal of the Korean Wood Science and Technology
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• 제10권3호
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• pp.133-134
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• 1982

This experiment has been made to investigate the absorption of watersoluble zinc chloride by Pinus densiflora S. et Z. at different moisture content, under soaking process, to decide the optimum content condition for the maximum absorption of zinc chloride by the wood tested and to investigate the concentration of zinc chloride affecting each moisture content of wood. Material was cut in the Dept. of Forest, College of Agr. S.N.U. Suwon, Korea. Sample was divided into sap and heartwood group and cut $2{\times}2{\times}2\;cm$ in size, having exact three dimensions, using the part of D.B.H. The numbers of sample were 20 pieces for each moisture content condition for both sap and heartwood. Especially, the samples were protected from exposure to keep moisture content in green condition. The ranges of moisture content tested were as the table 3 and 4. The conclusions were as follows: 1. With 3% zinc chloride solution, the rate of absorption decreased with the time increased, if the air seasoned Korean red pine (Pinus densiflora S. et Z.) was treated in steeping process. Initial absorption for 30 minutes was more than 50% of total absorpon for 24 hours. 2. Rate of absorption was same under the green condition, while rate of absorption under the moisture content 7 to 30% varied. 3. Although it was not quite proportional change in the absorption with the difference of moisture content, the great change in the absorption occured by seasoning. With exception sap green condition, sapwood twice more permeable than the heartwood in the oven dried condition and it has been observed the nearly same amount of absorption at the moisture content of 7%, 10% and 15% respectively in heartwood. 4. It was better from water in wood from view-point of absorption of zinc chloride solution, but it was difficult practically to obtain the smallest moisture content, and then it was decided that values of allowable moisture content, on the basis of mean absorption, were 15% to 20% in the sapwood, and in the heartwood, 10% to 15%. The mean absorption for each moisture content in the sap and the heartwood were as following. 5. In general, the concentration of zinc chloride after steeping was nearly same between moisture content and sap and heartwood respectively.

• 통합자연과학논문집
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• 제15권4호
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• pp.171-177
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• 2022

ROS1 (c-ros oncogene) is one of the gene with mutation in NSCLC (non-small cell lung cancer). The increased expression of ROS1 is leading to the increase proliferation of cell, cell migration and survival. Crizotinib and Entrectinib are the drugs that have been approved by FDA against ROS1 protein, but recently patients started to develop resistance against Crizotinib and there is a need of new drug that could act as an effective drug against ROS1 for NSCLC. In this study, we have performed virtual screening, where compounds are taken from Zinc 15 dataset and molecular docking was performed. The top compounds were taken based upon their binding affinity and their interactions with the residues. The compounds stability and chemical reactivity was also studied through Density Functional theory and their properties. Further study of these compounds could reveal the required information of ROS1-inhibitor complex and in the discovery of potent inhibitors.

• 한국식품영양과학회지
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• 제38권9호
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• pp.1174-1178
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• 2009

본 연구는 아연 공급 수준이 비만과 관련된 당대사 이상과 체내 무기질 함량에 미치는 영향을 알아보기 위하여 고지방식이 유도 비만쥐에게 아연을 요구량의 50%, 100%, 200% 수준으로 공급한 후 혈당, 인슐린 및 혈청 아연, 마그네슘, 크롬 함량을 측정하였다. 사료섭취량, 체중증가량, 사료효율 및 각 조직의 무게는 아연 공급 수준에 따른 유의적인 차이를 보이지 않았다. 그러나 혈당과 인슐린 농도는 아연 공급수준에 따라 유의적인 차이를 보여 혈당은 아연 과잉군이 결핍군과 적정군보다 유의적으로 낮게 나타났지만(p<0.05), 인슐린 농도는 아연 과잉군이 결핍군과 적정군보다 유의적으로 높았다(p<0.05). 혈청 아연과 크롬 함량은 아연 공급량에 따른 유의적인 영향을 받지 않았으나, 혈청 마그네슘 함량은 아연 결핍군이 다른 두 군보다 유의적으로 높게 나타났다(p<0.05). 결론적으로 비만군에서 아연 공급 수준에 따라 체내 당대사 및 그와 관련된 무기질 일부가 변화되는 것을 관찰할 수 있었다. 그러므로 비만군에게 아연을 보충 급여하면 인슐린 농도가 증가하며 그 결과 비만으로 발생될 수 있는 고혈당을 낮추는 효과가 있을 것으로 사료된다.

• 한국분말재료학회지
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• 제20권5호
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• pp.371-375
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• 2013

ZnO nanoparticles in the size range from 5 to 15 nm were prepared by zinc-lithium-acetate system. The morphologies and structures of ZnO were characterized by TEM, XRD and FT-IR spectra. UV-visible results shows that the absorption of ZnO nanoparticles is blue shifted with decrease in particles size. Furthermore, photoluminescence spectra of the ZnO nanoparticles were also investigated. The ZnO nanoparticles have strong visible-emission intensity and their intensities depend upon size of ZnO nanoparticles.

• 한국결정성장학회지
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• 제22권1호
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• pp.15-18
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• 2012

Transparent conductive indium zinc oxide thin films were prepared by spin-coating a sol-gel solution. Zinc acetate dihydrate [$Zn(CH_3COO)_2{\cdot}2H_2O$] and indium acetate [In$(CH_3COO)_3$] were used as starting precursors, and 2-methoxyethanol with 1-propanol as solvents. Upon annealing in a temperature range from 500 to $1000^{\circ}C$, the thin film crystallizes into polycrystalline $In_2O_3$(ZnO). The lowest electrical resistivity was obtained at an annealing temperature of $700^{\circ}C$ as $2{\Omega}{\cdot}cm$. Average optical transmittances were higher than 80% at all annealing temperatures. These experimental results confirm that the sol-gel spin-coating can be a good simplified practical method for forming transparent electrodes.

• 한국임상약학회지
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• 제31권2호
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• pp.136-144
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• 2021

Background: Zinc is known for modulating antiviral and antibacterial immunity and regulating inflammatory response. This study aimed to examine the effect of zinc supplementation on clinical outcomes of hospitalized COVID-19 patients through systematic literature review and meta-analysis. Methods: PubMed/Medline, Embase, and Cochrane library databases were searched for studies comparing zinc supplement group versus control group for clinical outcomes of COVID-19 up to November 3, 2020. The search results were updated on February 9, 2021. The meta-analysis was performed by RevMan 5.4 software. Results: Total 4 studies were included in this systematic review. The zinc administered group had a significantly lower mortality rate compared with the control group (odds ratio [OR] 0.63, 95% confidence interval [95% CI] 0.53-0.75, p<0.001), with significantly higher discharge rate (OR 1.32, 95% Cl 1.15-1.52, p<0.001). However, there were no significant differences in the intensive care unit admission rate (OR 1.07, 95% Cl 0.26-4.48, p=0.92), mechanical ventilation rate (OR 0.80, 95% Cl 0.45-1.41, p=0.44), and length of hospital stay (mean difference 0.75, 95% Cl -0.64 to 2.13, p=0.29) between the two groups. Conclusion: The meta-analysis of zinc administration showed positive clinical effects on the discharge rate and mortality of COVID-19 hospitalized patients. However, large-scale randomized controlled trial should be conducted for zinc to be considered as one of the adjuvant treatments.

• Asian-Australasian Journal of Animal Sciences
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• 제26권11호
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• pp.1569-1576
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• 2013

The study was conducted to evaluate the effect of vitamin E and zinc supplementation on energy metabolites, lipid peroxidation, and milk production in peripartum Sahiwal cows. For this, thirty-two pregnant dry Sahiwal cows were selected at sixty days prepartum and divided into four groups viz control, $T_1$, $T_2$, and $T_3$ of eight each. Group $T_1$ were supplemented with zinc at 60 ppm/d/cow, group $T_2$ were supplemented with vitamin E at 1,000 IU/d/cow and group $T_3$ were supplemented with combination of vitamin E at 1,000 IU/d/cow and zinc at 60 ppm/d/cow during d 60 prepartum to d 90 postpartum. Blood samples were collected on d -60, -45, -30, -15, -7, -3, 0, 3, 7, 15, 30, 45, 60, 90, and 120 with respect to day of parturition and analysed for glucose, non esterified fatty acid, and thiobarbituric acid reactive substance. Body condition score was maintained significantly better (p<0.05) in $T_3$ than in the control, $T_1$ and $T_2$ groups. Overall glucose level was higher (p<0.05) in $T_3$ than control, $T_1$, and $T_2$ groups. Levels of nonesterified fatty acid, and thiobarbituric acid reactive substance were lower (p<0.05) in $T_3$ than control, $T_1$, and $T_2$ groups. Milk yield was higher (p<0.05) in $T_3$ than control, $T_1$, and $T_2$ groups. In conclusion, the present study indicated that the supplementation of vitamin E and zinc in peripartum Sahiwal cows enhanced milk production by reducing negative energy balance.

• Asian-Australasian Journal of Animal Sciences
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• 제17권12호
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• pp.1635-1640
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• 2004

Two experiments were conducted to evaluate developmental gene expression of antimicrobial peptide PR-39 and effect of zinc oxide on gene regulation of PR-39 in piglets using semi-quantitative RT-PCR analysis. In experiment 1, fifteen female Tai-Hu pigs (a local breed in China) in five groups, each of three pigs at 1, 14, 28, 42 and 56 days of age were used to determine effect of age and weaning on mRNA expression of PR-39. In experiment 2, nine groups of pigs (total seventy-two female 36 days-age weanling Tai-Hu piglets) were assigned to three treatments (${ZnO}_0$, ${ZnO}_{100}$ and ${ZnO}_{3000}$). The feeding experimental period lasted 15 days. After feeding experiment, nine pigs with three animals in each treatment were chosen to determine the effect of ZnO on PR-39 mRNA expression of pigs. The results showed that PR-39 mRNA levels increased steadily in postnatal day 1-28 (preweaning), and weaning significantly decreased PR-39 mRNA expression of piglets (p<0.05). ${ZnO}_{3000}$ (3,000 mg zinc/kg diet) significantly increased PR-39 mRNA expression (p<0.05) when piglets were feed ${ZnO}_{3000}$ diet for 15 days. ${ZnO}_{100}$ (100 mg zinc/kg diet) also increased PR-39 gene expression, but the result was not statistically significant (p>0.05). The result was in accordance with the effect of ${ZnO}_{3000}$ and ${ZnO}_{100}$ on weight gain of piglets and prevention of diarrhea.

• Transactions on Electrical and Electronic Materials
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• 제8권5호
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• pp.201-205
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• 2007

Low temperature sintering behavior and microwave dielectric properties of the $BiNbO_{4^-}$ and the $ZnNb_2O_{6^-}zinc$ borosilicate glass(ZBS) systems were investigated with a view to applying the composition to LTCC technology. The addition of $10{\sim}30$ wt% ZBS in both systems ensured successful sintering below $900^{\circ}C$. For the $BiNbO_{4^-}ZBS$ system, the sintering was completed when 15 wt% ZBS was added whereas 25 wt% ZBS was necessary for the $ZnNb_2O_{6^-}zinc$ system. Secondary phase was not observed in the $BiNbO_{4^-}ZBS$ system but a small amount of $ZnNb_2O_6$ with the willemite structure as the secondary phase was observed in the $ZnNb_2O_{6^-}ZBS$ system. In terms of dielectric properties, the application of the $BiNbO_{4^-}$ and the $ZnNb_2O_{6^-}ZBS$ systems sintered at $900^{\circ}C$ to LTCC were shown to be appropriate; $BiNbO_{4^-}15$ wt% ZBS($\varepsilon_r=25,\;Q{\times}f\;value=3,700GHz,\;\tau_f=-32ppm/^{\circ}C$) and $ZnNb_2O_{6^-}25$ wt% ZBS($\varepsilon_r=15.8,\;Q{\times}f\;value=5,400GHz,\;\tau_f=-98ppm/^{\circ}C$).

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제25권1호
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• pp.79-86
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• 2022

Purpose: To determine the effect of zinc deficiency on fecal protein, electrolyte, and short-chain fatty acid levels in both heat-stable (ST) and heat-labile (LT) enterotoxigenic Escherichia coli (ETEC)-induced diarrhea in rats. Methods: Albino rats, weighing 100 to 150 g, were divided into 2 groups, with 15 animals each: non-zinc and zinc-deficient. These two groups were sub-divided into three sub-groups with five rats each: control (saline); LT-ETEC; and ST-ETEC. Sodium phytate (30 mmol/L) was added to the animals' water to induce zinc deficiency, while diarrhea was induced using 5×10⁹ ETEC cells/mL. Fecal protein levels were estimated using the Bradford method, while sodium and potassium levels were determined using atomic absorption spectrophotometry. Short-chain fatty acids were measured using gas chromatography-mass spectrometry. Results: Among the non-zinc and zinc-deficient groups, there were significant increases (p=0.04), (p=0.03) in fecal protein concentrations (mg/mL) in the LT-ETEC- (4.50±0.33), (6.50±0.26) and ST-ETEC- (3.85±0.19), (5.98±0.32) induced groups compared to the control groups (2.60±0.52), (3.50±0.11) respectively. Fecal sodium and potassium levels (mg/L) were significantly (p=0.029) increased in non-zinc-deficient rats induced with LT-ETEC (9.35±0.95, 1.05±0.48), and ST-ETEC (9.96±1.02, 1.21±0.45) compared with the control group (8.07±0.44, 0.47±0.17) but the increase were not statistically significant (p=0.059) in the zinc deficient rat groups. Fecal acetate and propionate levels (mg/g) significantly (p=0.032) increased when induced with LT-ETEC and ST-ETEC in non-zinc and zinc-deficient groups compared with the control groups. Conclusion: Zinc deficiency among rats with ETEC-induced diarrhea elevated fecal protein loss but may not have an effect on fecal sodium, potassium and short-chain fatty acid levels.