• Title/Summary/Keyword: Z-N-feruloyltyramine

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Studies on the Constituents of Hibiscus syriacus (I) (무궁화나무의 성분 및 생물활성에 관한 연구(I))

  • Lee, In-Kyoung;Ryoo, In-Ja;Choung, Dong-Ho;Han, Kyou-Hoon;Yun, Bong-Sik;Yoo, Ick-Dong
    • Korean Journal of Pharmacognosy
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    • v.28 no.3
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    • pp.112-116
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    • 1997
  • Hibiscus syriacus L. (Malvaceae) is widely distributed over Korean, China, India and Siberia. The dried flower of Hibiscus syriacus is used as a folk medicine for curing of hematochezia, dysentery, obstruction due to wind-phlegm, regurgitation, and vomiting of food, and the dried root bark is used antipyretic, anthelmintic and antifungal agents. From a chloroform extract of root bark of this plant, compound I, II, and III were isolated and the structures were elucidated by various spectroscopic analyses. These compounds were identified as syringaresinol. E-N-feruloyltyramine, and Z-N-feruloyltyramine, respectively and were isolated from this plant for the first time. Compound II and III exhibited lipid peroxidation inhibitory activities with $IC_{50}$ of 15.5 and 28.6 ${\mu}g/ml$, respectively.

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