• Archives of Plastic Surgery
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• 제37권6호
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• pp.843-846
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• 2010

Purpose: Plastic surgeon can easily misdiagnose the mass on the postoperative scar as hypertrophic scar. We present a case of endometrioma at abdominal scar after cesarean section. Methods: A 36 year-old female visited with a protruding, rubbery hard mass on her abdominal scar. The mass grew slowly after cesarean section performed 7 years ago. She has felt intermittent pain, not with menstrual cycle, for 2 months. The ultrasonography showed a solid irregular, ill defined mass with heterogenous echogenicity. The MRI finding is suggestive of malignant soft tissue tumor with deep fascial invasion. Incisional biopsy showed acanthosis, melanophage, lymphoplasmacytic infiltration. So we excised mass elliptically, we could see chocolatelike discharge from the mass, adhering to external oblique muscle fascia. The mass confirmed histologically as an endometrioma. Results: The mass was completely removed and did not recurr. The patient does not complain more about pain or any discomfort. Conclusion: Plastic surgeons should be aware of the possibility of endometrioma when the patient present with mass on her abdominal scar after surgery of the pelvis and abdomen.

• Archives of Plastic Surgery
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• 제37권4호
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• pp.492-495
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• 2010

Purpose: Facial tumor excision is a common cause of lower eyelid defect in old patients. Many methods have been introduced for the reconstruction of lower eyelid. However, conventional surgical method can cause various complications like scar, ectropion and unnatural color matching. Thus, we introduce a simple and aesthetically acceptable method for the reconstruction of lower eyelid defect. Methods: Three elderly patients with skin cancer in the unilateral lower eyelid were operated by the new method. Following a wide excision of skin cancer, subcilliary incision of lower blepharoplasty was carried out. Elevated skin flap of lower eyelid was redrapped for the correction of defect and the remnant skin from lateral portion of lower eyelid was used for full thickness skin graft (FTSG) to correct the remaining defect. Results: All grafts survived and color match of the graft was excellent without ectropion. Furthermore, wrinkles of the lower eyelid were improved after the blepharoplasty. Conclusion: Lower eyelid defect resulting from wide excision of malignant tumor in old patients could be reconstructed successfully by modifying the conventional lower eyelid blepharoplasty along with FTSG using the remnant skin.

• 한국산업보건학회지
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• 제5권1호
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• pp.40-47
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• 1995

We analyzed sytrene concentrations in air and in blood, mandelic acid in urine, and chromosome aberrations in peripheral lymphocytes of twenty one styrene-exposed workers in two reinforced plastic factories. In addition, in vitro testing for chromosome aberration was carried out. The dose-dependent clastogenicity of styrene was confirmed in the cultured Chinese hamster lung cell(CHL) with metabolic activation. The environmental styrene concentrations and urinary mandelic acid levels of analyzed subjects were different in two plants examined, but the exposure levels in most workers examined were lower than the permissible exposure levels. Chromosome aberrations of the styrene exposed workers showed no increase in the percentage of aberrant cells as compared with the control group. No correlation was found between the exposure levels and the frequencies of chromosome aberrations in workers.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2003년도 추계학술대회
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• pp.68-83
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• 2003

Welders working in a confined space, like in the shipbuilding industry, are at risk of being exposed to high concentrations of welding fumes and developing pneumoconiosis or other welding-fume exposure related diseases. Among such diseases, manganism resulting from welding-fume exposure remains a controversial issue, as the movement of manganese into specific brain regions has not been clearly established.(omitted)

• Parasites, Hosts and Diseases
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• 제41권4호
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• pp.189-196
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• 2003

In order to evaluate the possible roles of secretory proteases in the pathogenesis of amoebic keratitis, we purified and characterized a serine protease secreted by Acanthamoeba lugdunensis KA/E2, isolated from a Korean keratitis patient The ammonium sulfate-precipitated culture supernatant of the isolate was purified by sequential chromatography on CM-Sepharose, Sephacryl S-200, and mono Q-anion exchange column. The purified 33 kDa protease had a pH optimum of 8.5 and a temperature optimum of $55^{\circ}C$. Phenylmethylsulfonylfluoride and 4-(2-Aminoethyl)-benzenesulfonyl-fluoride, both serine protease specific inhibitors, inhibited almost completely the activity of the 33 kDa protease whereas other classes of inhibitors did not affect its activity. The 33 kDa enzyme degraded various extracellular matrix proteins and serum proteins. Our results strongly suggest that the 33 kDa serine protease secreted from this keratopathogenic Acanthamoeba play important roles in the pathogenesis of amoebic keratitis, such as in corneal tissue invasion, immune evasion and nutrient uptake.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2011년도 제36회 춘계학술대회논문집
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• pp.109-112
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• 2011

한국형발사체 추진기관 개발을 위한 연소기 연소시험설비와 터보펌프 실매질 시험설비의 배치 및 설계에 대해 간략히 기술하였다. 연소기 연소시험설비 및 터보펌프 실매질 시험설비에서 75톤급 액체로켓엔진의 부품인 연소기 및 터보펌프의 개발 및 인증시험을 수행할 예정이다. 연소기 및 터보펌프 시험설비의 유공압 설비, 제어계측 시스템, 시험 스탠드 그리고 부대설비에 대한 상세설계를 완료하였다.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-1
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• pp.72-72
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• 2003

Welders working in a the confined space, like in the shipbuilding industry, are have at risk of being exposed toing a high concentrations of welding fumes and of developing pneumoconiosis or other welding- fume exposure related diseases. Among such diseasesthem, manganism resulting fromcaused by welding- fume exposure remains ais still controversial issue, as the movement ofnd no clear demonstration of manganese movement into the specific brain regions has not been clearly established. (omitted)

• Parasites, Hosts and Diseases
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• 제60권4호
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• pp.247-254
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• 2022

Vincristine (VCR) is a chemotherapeutic agent widely used in treatment of malignancies. However, VCR has a limitation in use since it commonly causes a painful neuropathy (VCR-induced peripheral neuropathy, VIPN). Inflammatory cytokines secreted by immune cells such as macrophages can exacerbate allodynia and hyperalgesia, because inhibiting the inflammatory response is a treatment target for VIPN. In this study, we investigated whether Trichinella spiralis, a widely studied helminth for its immunomodulatory abilities, can alleviate VCR-induced allodynia. Von Frey test showed that T. spiralis infection improved mechanical allodynia at 10 days after VCR injection. We further observed whether the difference was due to mitigated axon degeneration, but no significant difference between the groups in axonal degeneration in sciatic nerves and intra-epidermal nerve fibers was found. Conversely, we observed that number of infiltrated macrophages was decreased in the sciatic nerves of the T. spiralis infected mice. Moreover, treatment of T. spiralis excretory-secretory products caused peritoneal macrophages to secrete decreased level of IL-1β. This study suggests that T. spiralis can relieve VCR-induced mechanical allodynia by suppressing neuroinflammation and that application of controllable degree of helminth may prove beneficial for VIPN treatment.

• 한국작물학회지
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• 제31권4호
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• pp.416-419
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• 1986

본 실험은 우리나라 참깨의 단작, 맥후작별 vinyl mulching 재배하에서의 도복방지효과를 보고자 장려품종인 안산깨. 단백깨, 광산깨를 공시하여 개화초기에 75$^{\circ}$ 45$^{\circ}$의 인위도복 처리와 도복방지 처리로서 개화시에 지주를 세워 처리간의 효과를 조사했던 바, 그 결과를 요약하면 다음과 같다. 1. 개화초기에 75$^{\circ}$ 도복은 도복되지 않은 것에 비해 가장 감수정도가 커서 단작에서 75%, 맥후작에서 81% 감수되었다. 2. 개화초기의 무처리한 구에서는 단작직파에서 약간의 자연도복이 되어 18% 감수되었고 맥후작직파에서는 태풍피해로 75%의 큰 감수를 보였다. 3. 단작, 맥후작별 vinyl mulching 재배에서 개화초기에 지주를 세워 재배한 처리는 완전다수였다.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2022년도 춘계학술대회
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• pp.484-487
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• 2022

이 연구에서는 생산기간에 따른 치밀오일 저류층의 미래 생산성을 예측하기 위해 XAI(eXplainable Artificial Intelligence) 기반의 머신러닝 모델을 제시하였다. XAI 알고리즘은 해석 가능한 인공지능을 뜻하며 예측한 최종 결과의 근거와 도출 과정의 타당성을 제공한다. 본 연구에서는 현장자료를 기반으로 데이터전처리를 수행한 후 생산 초기와 후기의 생산성을 예측하는 지도학습 모델을 제안하고, 모델의 결과를 바탕으로 XAI를 이용하여 생산성 예측 모델의 영향을 미치는 인자를 분석하였다.