• Title/Summary/Keyword: YoungChu

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Clinical Applications of 3T MR Spectroscopy

  • Choe, Bo-Young;Baik, Hyun-Man;Chu, Myung-Ja;Jeun, Sin-Soo;Kang, Sei-Kwon;Chung, Sung-Taek;Park, Chi-Bong;Oh, Chang-Hyun;Lee, Hyoung-Koo
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.345-351
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    • 2002
  • The purpose of this study was to assess clinical proton MR spectroscopy (MRS) as a noninvasive method for evaluating brain tumor malignancy at 3T high field system. Using 3T MRI/MRS system, localized water-suppressed single-voxe1 technique in patients with brain tumors was employed to evaluate spectra with peaks of N-acetyl aspartate (NAA), choline-containing compounds (Cho), creatine/phosphocreatine (Cr) and lactate. On the basis of Cr, these peak areas were quantificated as a relative ratio. The variation of metabolites measurements of the designated region in 10 normal volunteers was less than 10%. Normal ranges of NAA/Cr and Cho/Cr ratios were 1.67${\pm}$018 and 1.16${\pm}$0.15, respectively. NAA/Cr ratio of all tumor tissues was significantly lower than that of the normal tissues (p=0.005), but Cho/Cr ratio of all tumor tissue was significantly higher (p=0.001). Cho/Cr ratio of high-grade gliomas was significantly higher than that of low-grade gliomas (P=0.001). Except 4 menigiomas, lactate signal was observed in all tumor cases. The present study demonstrated that the neuronal degradation or loss was observed in all tumor tissues. Higher grade of brain tumors was correlated with higher Cho/Cr ratio, indicating a significant dependence of Cho levels on malignancy of gliomas. Our results suggest that clinical proton MR spectroscopy could be useful to predict tumor malignancy.

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A Web-based Rapid Fabrication System for Optical Components (광학 부품의 웹 기반 쾌속제작 시스템)

  • Baek, Chang-Il;Chu, Won-Sik;Jung, Woo-Byeok;Jeon, Woo;Kim, Chi-Wan;Sung, Mi-Jung;Kang, Ji-Young;An, Sung-Hoon
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2003.06a
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    • pp.30-33
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    • 2003
  • In this paper the advantage of web technology applied to Rapid Prototyping is discussed. Two fabrication processes are chosen to be web-enabled. One, a post-process of FDM is developed to provide translucent plastic parts made of medical grade ABS material. The other, a system to fabricate laser machined Light Guide Panel is developed. In order to show the timesaving characteristics of the web-based tools, two websites are implemented (http://nano.gsnu.ac.kr/fdm & http://nano.gsnu.ac.kr/laser). The 3-tier architecture is applied for the Internet communication between designers and manufacturing sites, The integrated design tools and physical manufacturing processes enable designers to submit a new design and to receive the fabricated parts in an expedited manner. Example parts are fabricated using the web-based system to prove the concept of the web-based design and Rapid Prototyping.

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Profile of Hanwoo Steer Carcass Characteristics, Meat Quality and Fatty Acid Composition after Feeding Italian Ryegrass Silage

  • Kim, Won Ho;Kang, Suk-Nam;Arasu, Mariadhas Valan;Chu, Gyo-Moon;Kim, Da Hye;Park, Jae-Hong;Oh, Young Kyoon;Choi, Ki Choon
    • Food Science of Animal Resources
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    • v.35 no.3
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    • pp.299-306
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    • 2015
  • The objective of this work was to evaluate the growth performance, feed intake, slaughter characteristics, meat quantity and quality characteristics of Hanwoo steers fed with Italian ryegrass (IRG) silage (TRT). IRG silage consisted 11.70% protein, 2.84% ether extract, 53.50% dry matter digestibility and 63.34% total digestible nutrients. The daily weight gain and feed conversion ratio of TRT were significantly (p<0.01) higher than that of control diet (CON; fed rice straw) in the whole periods. However, the slaughter weight, dressing percentage, quantity grade and quantity traits (marbling score, meat color, fat color, and quality grade) of either TRT or CON were similar. Meat fed TRT diet showed higher crude fat and lightness (L*) value and lower moisture content and pH value compared with the CON diet (p<0.05). Overall the carcass yield was 12.5% higher than CON diet.

Solubility of Ibuprofen in Supercritical Carbon Dioxide (초임계 이산화탄소를 이용한 Ibuprofen의 용해도 측정)

  • Kim, Young Ae;Chu, Junho;Lim, Jong Sung;Kim, Hwayoung;Lee, Youn-Woo
    • Clean Technology
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    • v.11 no.3
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    • pp.147-152
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    • 2005
  • For estblishing the best technique for the micronization of Ibuprofen using supercritical fluids, the solubility should be known. The solubility of Ibuprofen in supercritical carbon dioxide was measured by observing the cloud point. The cloud point was observed using high pressure equipment equipped a variable volume view cell between temperature of 35, 40 and $45^{\circ}C$. The solubility data was correlated by the Peng-Robinson equation of state Solute physical properties, such as critical temperature (Tc), critical pressure (Pc) and acentric factor (${\omega}$) were estimated by the some group contribution method. As pressure was increased, the solubility increased at constant temperature. The retrograde phenomenon by a solute vapor pressure and a density of solvent was observed at the pressure of around 150bar. It was found that $CO_2$ can be used as a supercritical solvent in micronization of ibuprofen by RESS.

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Comparative Study of Ready-to-made Denim Pants according to Pattern Analysis and Appearance Evaluation (패턴분석 및 착의평가에 의한 기성복 청바지의 비교연구)

  • Suh Chu-Yeon;Suk Eun-Young;Park Soon-Jee
    • Korean Journal of Human Ecology
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    • v.7 no.3
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    • pp.5-13
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    • 2004
  • This study was performed to investigate the characteristics of denim pants preferred by Korean women in their 20's through the analysis of the sensory test(appearance) and garment space length. Four kinds of ready-made denim pants of national and licensed brand on sale in Korea were used as the experimental garment. The results were as follows: 1. The significant difference among brands were found in the appropriateness of ease in the part of waist belt(front), knee (front), ankle(back) and the total silhouette. 2. In the analysis of garment space length. the significant difference among brands was shown in waist belt part $(FL60^{\circ})$, hip $(FL0^{\circ},\;FL30^{\circ})$, crotch(SRR) and knee(BR60^{\circ}). However, total average was not significant difference. 3. According to analysis of pattern size, the brand N was out of balance in crotch depth and girth. by which it can be said that N got the lowest score in sensory test (appearance). On the other hand, Brand GU was large in circumference with short crotch length. 4. Therefore, the most preferred denim pants pattern of Korean women in their 20's was fit in waist belt. hip. crotch circumference and a little bit tight in crotch depth and length. As the design was limited as straight style. more design and brands must be included for future study.

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A Study on the Status and Improvement Plan of Alternative Habitats - Based on the Projects Subject to Environmental Impact Assessment - (대체서식지 조성 현황 및 개선방안 연구 - 환경영향평가 대상 사업을 중심으로 -)

  • Shim, Yun-Jin;Jung, Gyu-Jong;Eo, Yang-Joon;Ryu, Yoon-Jin;Park, Hyun-Kyung;Kim, Dong-Hwan;Cho, Young-Ho;Yoon, Ju-Duk;Woo, Seung-Hyun;Park, Su-Gon;Jang, Eun-Hye;Chu, Yun-Soo;Park, Yong-Su
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.21 no.2
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    • pp.77-85
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    • 2018
  • The intensive habitats loss of natural organisms as a consequence of anthropogenic activities has lead to the use of alternative habitats for species conservation. We reviewed the current status of alternative habitats and suggest the improvement of alternative habitats. Most of alternative habitats regarded in this study are not following the pre-arranged consultation at environmental impact assessment. These alternative habitats are rendered useless due to the insufficient consideration of ecological characteristics of species and lack of detailed plans. A number of alternative habitats are influenced by disturbance such as environmental pollution and construction. Post-monitoring of alternative habitats are needed to estimate immigration rate of species. Post management is also needed to assess the status of population stability. Overall, low effectiveness of alternative habitats is presented in this study. According to the status survey, methods for improvement of alternative habitats are required such as detailed guidelines, establishment of post-monitoring system, improvement of habitat restoration techniques, and guidelines for management and operation of alternative habitats.

MR Arthrography of the Labral-Capsular-Ligamentous Complex: Normal Variations and Pitfalls (관절와순낭인대(Labral-Capsular-Ligamentous) 복합체의 자기공명관절 조영술 : 정상변이 및 진단시 주의점)

  • Han Sung Ho;Yang Bo Kyu;Kim Chi Hong;Ahn Tae Won;Chu Wu Jun
    • The Academic Congress of Korean Shoulder and Elbow Society
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    • 1997.05a
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    • pp.164-166
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    • 1997
  • MR arthrography is a useful modality for evaluating the labrocapsular ligamentous complex(LOLC) of the shoulder. This study was performed to describe normal anatomic variations and pitfalis in image interpretation related to evaluation of the LOLC. MR Arthrogram of 56 shoulders in 41 asymptomatic young, active volunteers were prospectively reviewed to evaluate the labral shapes. capsular insertions and images which may mimic the lesions of glenohumoral instability. The anterior and posterior parts of the labra. respectively. varied in shape: triangular$(72\%,\; 36\%)$. round $(13\%,\; 35\%)$. cleaved$(8\%,\; 1\%)$. notched$(2\%,\; 0\%)$. flat$(5\%,\; 24\%)$ and absent$(0\%,\; 4\%)$. The anterior and posterior capsular insertions. respectively. varied in sites: Mosely and Oevergaard type I$(82\%,\;62\%)$, type II$(13\%,\; 3\%)$ and type III $(5\%,\; 2\%)$. A number of pitfalls in image interpretation were discovered. Articular cartilage undercutting the labrum$(29\%)$ and middle glenohumoral ligament in proximity to anterior labrum $(5\%)$ simulated a labral tear. Joint fluid interposed in the central. superior portion of the sublabral sulci$(25\%)$ simulated a SLAP lesion. Synovial fold$(38\%)$ in axillary pouch resembled a loose body. Knowledge of normal variations and pitfalls in MR arthrogram image interpretation of labral capsular - ligamentous complex will help the orthopedist to accurately detect debilitating derangements associated with the glenohumeral instability.

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Subcutaneous Four-Week Repeated Dose Toxicity Studies of Rice Cell-Derived Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor in Rats

  • Ji, Jung-Eun;Lee, Jung-Min;Choi, Jong-Min;Choi, Young-Hwa;Kim, Eun-Kyung;Chu, So-Jung;Kim, Seok-Kyun;Ahn, Kyong-Hoon;Lee, Dong-Hoon;Kim, Ha-Hyung;Han, Kyu-Boem;Kim, Dae-Kyong
    • Toxicological Research
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    • v.24 no.4
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    • pp.315-320
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    • 2008
  • Recombinant human granulocyte-macrophage colony stimulating factor (hGM-CSF) is a glycoprotein and hematopoietic growth factors that regulates the proliferation of myeloid precursor cells and activates mature granulocytes and macrophages. In a previous study, we reported that hGM-CSF could be produced in transgenic rice cell suspension culture, termed rhGM-CSF. In the present study, we examined the repeated dose toxicity of rhGM-CSF in SD rats. The repeated dose toxicity study was performed at each dose of 50 and 200 ${\mu}g/kg$ subcutaneous administration of rhGM-CSF everyday for 28-days period. The results did not show any changes in food and water intake. There were also no significant changes in both body and organ weights between the control and the tested groups. The hematological and blood biochemical parameters were statistically not different in all groups. These results suggest that rhGM-CSF may show no repeated dose toxicity in SD rats under the conditions.

Aging Characteristics of Sn-1.8Bi-0.7Cu-0.6In Solder (스텐실 프린트법으로 인쇄한 Sn-1.8Bi-0.7Cu-0.6In 솔더의 고온 시효 특성)

  • Lee Jaesik;Cho Sun-Yun;Lee Young-Woo;Kim Kyoo-Suk;Cheon Chu-Seon;Jung Jae-Pil
    • Journal of the Microelectronics and Packaging Society
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    • v.12 no.4 s.37
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    • pp.301-306
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    • 2005
  • Aging characteristics of newly developed Sn-1.8Bi-0.7Cu-0.6In solder was evaluated by shear strength and microstructure. Stencil printing was applied to form solder. The shear strength of Sn-1.8Bi-0.7Cu-0.6In at $150^{\circ}C$ showed the highest values through aging. Intermetallic compounds formed on the interface between solder and Au/Cu/Ni/Al UBM were $(Cu,\;Ni)_6Sn_5$ Furthermore, it was found that Spatting of Intermetallic compounds started before 500h aging at $150^{\circ}C$.

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Phase Separation Characteristics of Low Temperature Bunsen Reactions In Sulfur-Iodine Hydrogen Production Process (황-요오드 수소 제조 공정에서 저온 분젠 반응의 상 분리 특성)

  • Han, Sang-Jin;Lee, Kwang-Jin;Kim, Hyo-Sub;Kim, Young-Ho;Park, Chu-Sik;Bae, Ki-Kwang;Lee, Jong-Gyu
    • Transactions of the Korean hydrogen and new energy society
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    • v.22 no.4
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    • pp.424-431
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    • 2011
  • The Sulfur-Iodine(SI) thermochemical hydrogen production process consists of three sections, which are so called the Bunsen reaction section, the $H_2SO_4$ decomposition section and the HI decomposition section. In order to identify the phase separation characteristics in the reaction conditions with the high solubility of $SO_2$, we conducted the Bunsen reaction at the low temperatures, ranging from 283 to 298K, with the $I_2/H_2O$ molar ratios of 2.5/16.0 and 3.5/16.0. The molar ratios of HI/$H_2SO_4$ products obtained from low temperature Bunsen reactions were ca. 2, indicating that there were no side reactions. The amount of reacted $SO_2$ was increased with decreasing the temperature, while the amounts of unreacted $I_2$ and $H_2O$ were decreased. In the phase separation of the products, the amount of a $H_2SO_4$ impurity in $HI_x$ phase was increased with decreasing the temperature, though the temperature has little affected on HI and $I_2$ impurities in $H_2SO_4$ phase.