• The Korean Journal of Cytopathology
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• v.12 no.1
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• pp.17-23
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• 2001

To evaluate the role of sputum and bronchial washing for the diagnosis of lung carcinoma, we studied the sensitivity of both cytologic techniques using the biopsy confirmed cases from 228 patients. Among them, 123 cases were squamous cell carcinomas, 42 cases were adenocarcinomas, 48 cases were small cell carcinomas, one case was large cell carcinoma, and 14 cases were other types of carcinoma including poorly differentiated carcinomas. Three hundreds and ninety two sputa and 173 sputa were obtained in the pre- and post-bronchoscopic periods. Bronchial washing had been taken once in each patient. The overall sensitivity of the sputum cytology was 0.52 and that of the bronchial washing 0.63, while it increased to 0.83 when a combination of both techniques. Squamous cell carcinomas were diagnosed to the great extent in which sensitivities were 0.59 and 0.74, in sputum and bronchial washing, respectively. The post-bronchoscopic sputa showed higher sensitivity (0.44) than pre-bronchoscopic sputa (0.30). The sensitivity on sputa increased from 0.34 to 0.49 when three samples were examined compared to the single examination. The accuracy of cell typing was 94.0% in sputa and 93.8% In bronchial washing. Repeated sputum examination including post-bronchoscopic sputa is warranted to Improve sensitivity and a complementary role of both cytologlc techniques can be postulated by these data.

• The Korean Journal of Cytopathology
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• v.9 no.1
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• pp.63-68
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• 1998

Fine needle aspiration cytology of "cold" nodules of the thyroid has proved to be of great value in their preoperative diagnosis. Most types of thyroid tumors are readily recognizable from characteristic cellular patterns in the smears of needle aspirates. But follicular neoplasms present some problems because the cytomorphology of the adenomas frequently is same as in carcinoma. For differentiation of benign from malignant follicular neoplasms of the thyroid we tested the usefulness of two objective parameters - nuclear area and perimeter - by morphometry. This study was made on fine needle aspirates from 30 cases with cytologic diagnosis of follicular neoplasm of thyroid. The histologic classification was follicular adenoma in 22 cases and follicular carcinoma in 8 cases. As a reference group we used seven caes with nodular hyperplasia. The smears of aspirates were stained by Papanicolaou method. On each slide 200 randomly selected cells with intact nuclei were measured. The mean value of nuclear area are $25.32{\pm}5.50{\mu}m^2,\;34.08{\pm}7.50{\mu}m^2\;and\;39.97{\pm}6.63{\mu}m^2$ in nodular hyperplasia, follicular adenoma, and follicular carcinoma, respectively. The mean value of perimeter are $19.48{\pm}2.26{\mu}m,\;22.95{\pm}2.65{\mu}m\;and\;24.78{\pm}2.23{\mu}m$ in nodular hyperplasia, follicular adenoma and follicular carcinoma, respectively. The mean nuclear areas and perimeters of cells from follicular adenoma were significantly larger than those from nodular hyperplasia (p<0.05). The mean nuclear areas and perimeters of cells from follicular carcinoma were larger than those from follicular adenoma but the differences are not significant statistically(p>0.05). Therefore, morphometric assessment alone is inadequate to predict malignancy in thyroid aspirates.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.4
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• pp.943-952
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• 2004

We studied on the purpose of comparing the original texts with quotations in edema chapter of Dong- Yi-Bo-Gam. The research mainly depended on compare and consider these original text and quote. In Pyong Yeol Byong chapter of SoMoon, Su Yeol Hyul chapter of SoMoon, Pyong Yin Ki Sang chapter of SoMoon, Ja Jeol Jin Sae chapter of YoungChu, Emperor's Classic of Internal Medicine(黃帝內經;ECIM), We were able to find that some sentences about edema were quoted. Drug arrangement order that construct herb medicine is disposed depends on drug's weight, and all unit was concorded by Jeon and Pun. Quoted words in Emperor's Classic of Internal Medicine(黃帝內經;ECIM) does not perfectly match with original text. However, edema chapter of Dong- Yi-Bo-Gam is identical with original text, because only few words were deleted or inserted.

• Biomolecules & Therapeutics
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• v.5 no.2
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• pp.125-132
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• 1997

Cisplatin, a platinum-complex, is currently one of the most effective compounds used in the treat-ment of solid tumors. However, its use is limited by severe side effects such as renal toxicity. Our platinum-based drug discovery program is aimed at developing drugs capable of diminishing toxicity and improving selective cytotoxicity. We synthesized new Pt (II) complex analogue containing 1,2-diaminocyclohexane (DACH) as carrier ligand and 1,2-bis (diphenylphosphino) ethane (DPPE) as a leaving group. Furthermore, nitrate was added to improve the solubility. A new series of [Pt(cia-DACH)(DPPE)] . $2NO_3$ (PC) was synthes-ized and characterized by their elemental analysis and by various spectroscopic techniques [infrared (IR), $_{13}$carbon nuclear magnetic resonance (NMR)] .PC demonstrated acceptable and significant antitumor activity against SKOV-3 and OVCAR-3 human ovarian carcinoma cell lines as compared with that of cisplatin. The cytotoxicity of PC in normal cells was found quite less than that of cisplatin using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), ($^3$H)thymidine uptake and glucose consumption tests in rabbit renal proximal tubular cells, human renal cortical cells and tissues. In conclusion, PC is considered to be more selective cytotoxicity toward human ovarian cancer cells than normal human/rabbit kidney cells.

• Korean Journal of Soil Science and Fertilizer
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• v.26 no.4
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• pp.249-252
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• 1993

Water culture studies were conducted in the greenhouse with mulberry plants to investigate the nutrient uptake, especially Zn and Cu, under high phosphrous concentration. Mulberry plants were grown with five phosphorus levels(0, 0.2, 0.5, 2.0, 5.0 mM). Leaves and roots were analyzed for water content, total nitrogen, P, K, Ca, Mg, Fe, Mn, total Zn, soluble Zn, Cu, Cl, $NO_3HPO_4$ and $SO_4$. Dry matter increased upto 2.0mM phosphorus level, and then decreased. Water content, total nitrogen, P, K, and Fe in leaves increased with increasing phosphorus level. Total Zn content in leaves showed little change, whereas soluble Zn increased and Cu decreased with increasing phosphorus level. With increasing phosphous level. $SO_4$ and Cl decreased and then sharply increased above 2.0mM phosphorus. Lower uptake of Cu and higher uptake of $SO_4$ and Cl suggest a cause of mulberry yield decline with high accumulation of soil phosphorus.

• Journal of Korean Society on Water Environment
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• v.26 no.5
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• pp.725-731
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• 2010

This study was to evaluate the ozone oxidation of dissolved Fe, Mn, $SO{_4}^{2-}$ ions and color in abandoned mining drainage by conducting a bench-scale operation at various reaction times in an ozone reactor. The influent was collected from an abandoned mine drainage (AMD) near the J Mine in Jungsungun, Kangwon Province. The ozone reactor was operated at ozone reaction times of 10, 20 and 30 min with ozone doses of 0.0 and $2.4g\;O_3/hr$. Samples from each effluent from subsequent sand filtration were regularly collected and analyzed for pH, Fe, Mn, Al, Cr, Hg, $SO{_4}^{2-}$, alkalinity, color, ORP, TDS and EC. The effluent concentrations of Fe and Mn from the sand filter were less than 0.1 mg/L, which were below the concentrations on Korean drinking water quality standards (Fe, Mn < 0.30 mg/L). The influent $SO{_4}^{2-}$, concentrations were not noticeably changed during this ozone oxidation. Cr and Hg in the raw wastewater from the abandoned mining drainage were not detected in this study. The experimental result shows that the ozone oxidation of dissolved heavy metals and subsequent sand filtration of metal precipitates are desirable alternative for removing heavy metals in AMD.

• Land and Housing Review
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• v.6 no.4
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• pp.231-237
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• 2015

Recently, It has been much interest in modular housing construction. so, The purpose of this study was to investigate the characteristics of the indoor air quality in modular mock-up housing. We measured indoor air quality(formaldehyde, benzene, toluene, ethylbenzene, xylene, styrene) of two modular mock-up units that built-in furniture is installed and uninstalled. As a result, the pollutants of built-in furniture installed unit were emitted more than built-in furniture uninstalled unit. But after bake-out and ventilation, emission concentrations of two modular mock-up units were similar and were below Indoor Air Quality recommendation standards. Built-in furniture is likely to affect the emission concentration of toluene

• Land and Housing Review
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• v.6 no.4
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• pp.215-220
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• 2015

The purpose of this study was to comparative analyses of energy performance in apartment houses adopted window frame-type natural ventilation, under-floor air distribution ventilation and heat recovery ventilation. As the object of energy simulation, the three type ventilation system with area of $84m^2$ was selected in apartment house. As a result, when the ECO2 simulation was performed, the 1st requirement quantity per annual were $159.9kWh/m^2yr$(CASE1, Natural Ventilation), $179.7kWh/m^2yr$(CASE2, Under-floor Air Distribution Ventilation) and $161.0kWh/m^2yr$(CASE3, Heat Recovery Ventilation).

• Korean Journal of Materials Research
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• v.14 no.9
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• pp.676-681
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• 2004

In-situ observation in SBM on the microfracture behavior of coating layer was performed for GA steel sheets that have various Fe contents and thickness of coating layer. In case of cross sectional side of coating layer that was in a tensile stress state during bending, fine perpendicular crack pre-induced during galvannealing grew and propagated rapidly toward the coating surface with the increase of strain. And then it grew and propagated along the ${\Gamma}/Fe$ matrix interface, and combined with the nearest another perpendicular crack. Consequently, flaking occurred. The more Fe content and thickness of coating layer increased, the more average crack interval and flaking resistivity increased. Exfoliation was little observed at coating surface in a tensile stress state.

• Korean Journal of Optics and Photonics
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• v.21 no.5
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• pp.185-189
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• 2010

We demonstrate a single-frequency wavelength tunable erbium-doped fiber (EDF) ring laser. We used an unpumped-EDF as a saturable-absorber in order to obtain a stable single-frequency with a narrow-linewidth single-polarization mode in the ring cavity. The lasing wavelength was controlled by using bending-induced strain, such as tension and compression strain corresponding to the bending direction, applied to the fiber gratings. The fiber laser exhibited an output power of -1.85 dBm at a wavelength of 1540.72 nm for a pumping power of ~400 mW. An extinction ratio was measured to be more than 60 dB. The proposed tunable fiber laser maintains nearly the same output power while its lasing wavelength is controlled over in a wavelength range of 5 nm.