• 대한핵의학회:학술대회논문집
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• 1990.04a
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• pp.186.2-187
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• 1990

• 시스템엔지니어링워크숍
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• s.7
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• pp.37-39
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• 2006

• The Journal of the Korean Society for Microbiology
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• v.35 no.5_6
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• pp.377-377
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• 2000

• Journal of English Language & Literature
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• v.64 no.3
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• pp.347-360
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• 2018

It is ironic but not coincidental that the loss of Korean sovereignty to Japan roughly paralleled the formation of the idea of Korean ethnic identity. The coalescence of the content of this heretofore amorphous notion of a "pure" and transcendental (in the class sense) ethnic essence was, again ironically, the result both of ideologies taken from (or given by) Japan and resistance to Japanese encroachment. What resulted was the birth of a hybrid (sub) consciousness that was able to accommodate disparate, or even contradictory, realities simultaneously without any sense of contradiction (Christian and shaman for example). If, as Kim Chul has asserted, the colonial period was the most impactful in forming today's Korean society and "giving birth" to today's Korean, it becomes easy to imagine how this formation process included elements of Japanese and western culture. This meant that there was going to be an inevitable cognitive dissonance when these influences collided with the imperatives of ethnic nationalism which became the touchstone for a common Korean identity (North and South). This paper attempts to show how this split-consciousness was manifested in Yeom Sang seop's Manse jeon with the aim of identifying how it affects discourses related to nationalism and identity.

• 한국데이터정보과학회:학술대회논문집
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• 2003.10a
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• pp.115-121
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• 2003

최근 빈번한 여름철 집중호우로 인하여 인명과 재산에 큰 피해를 보고 있다. 이러한 여름철 집중호우에 대한 시, 공간적 변동 특성 분석의 필요성이 증가되고 있다. 이에 최근에 빈번히 집중호우가 발생하는 한반도 남서 지역에 18개 관측 지점에 대해 1981년부터 2000년까지 시간별, 연도별 집중호우의 빈도수를 조사하였다. 분석결과, 최근에 집중 호우의 빈도는 증가하였으며 1일 집중호우 빈도는 해안지방이 많았으며, 시간당 집중호우 빈도는 해안지역 뿐만 아니라 산악 또는 내륙 지역에서도 증가하였다. 또한 시간별 집중호우는 해안지역의 경우에는 새벽에 많았으나 산악 또는 내륙 지역은 오후에 빈도수가 많았다. 월별 집중호우는 8월, 7월, 9월, 6월 순으로 많았다. 8월이 가장 많은 이유는 장마 종료 후 태풍의 영향이 컸음을 알 수 있다. 이러한 분석 결과를 기초로 하여 향후 한반도 남서 지역 집중 호우 발생에 대한 시..공간적 변동의 기후학적 특성에 대한 이해력 향상에 도움이 될 것이다.

• 한국데이터정보과학회:학술대회논문집
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• 2002.06a
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• pp.31-34
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• 2002

일반적으로 지형이나 지역적 조건으로 인하여 관측소의 위치가 일정하게 분포되어 있지 않다. 이러한 지역적으로 불균형적인 관측소의 분포는 프렉탈 차원으로 표시되어 질 수 있다. 즉 차원이 0 일 때는 모든 관측소가 하나의 장소에 있을 때이고 2 일 때는 모든 관측소가 균일하게 분포되어 있는 경우이다. 현재 우리나라의 관측소들의 위치를 관찰치로 하여 각 관측소간의 거리와 미리 주어진 거리와의 관계를 선형 회귀식을 구하여 프렉탈 차원을 구하였다. 각 관측소가 창설된 연도별 관측소의 위치를 추가함에 따라 프렉탈 차원의 변화를 계산하였다.

• Journal of Korean Medicine Rehabilitation
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• v.15 no.1
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• pp.67-75
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• 2005

목 적 : 면역 세포에서 주로 생성되는 사이토카인인 인터루킨-1 (interleukin-1)은 다양한 신경내분비계와 대사 기능에 영향을 미치며, 비만인의 말초혈액 단핵구에서 증가하는 경향이 있는 것으로 연구보고 되고 있다. 본 연구의 목적은 $IL-1{\alpha}$ 다형성과 사상체질이 비만과 관련이 있는지를 조사하는데 있다. 연구방법 : 본 연구에서는 현저한 체질량지수 (body mass index, BMI) 다양성을 보이는 건강한 한국 여성 182명을 대상으로 $IL-1{\alpha}$ 유전자형을 분석하였다. 결 과 : T 대립 유전자는 BMI 감소와 관련이 있었다. BMI $27-30kg/m^2$ 그룹(group III)에서 T 대립유전자의 빈도는 $25kg/m^2$ 미만의 그룹(group I)에 비하여 유의하게 감소하였다 (odds ratio, OR, 0.141; 0.25% CI, 0.04-0.54). 더욱이 태음인 여성에서 $IL-1{\alpha}$ T 대립유전자의 빈도가 normal group에 비하여 overweight group (BMI $27-29kg/m^2$)에서 명확하게 감소하였다 (OR, 0.139; 95% CI, 0.04-0.54). 결 론 : 본 연구에서 175명의 체질분석결과 $BMI{\geq}25$인 군들의 태음인의 빈도가 높았으며, BMI는 CC genotype를 가진 사람에서보다 CT+TT genotype를 가진 사람에게서 더 낮았다. 태음인에서 동형접합 또는 이형접합 T 대립유전자가 $BMI{\geq}25$인 군에서 유의하게 감소하였다. 이상의 결과는 한국 여성에서 $IL-1{\alpha}$ 유전자 조절부위에 위치한 -889C/T 다형성과 비만 및 사상체질의 관련되는 것을 의미한다.

• Molecules and Cells
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• v.25 no.1
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• pp.55-63
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• 2008

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by the selective death of motor neurons. Mutations in the SOD1 gene are responsible for a familial form of ALS (FALS). Although many studies suggest that mutant SOD1 proteins are cytotoxic, the mechanism is not fully understood. To investigate the role of mutant SOD1 in FALS, human SOD1 genes were fused with a PEP-1 peptide in a bacterial expression vector to produce in-frame PEP-1-SOD fusion proteins (wild type and mutants). The expressed and purified PEP-1-SOD fusion proteins were efficiently transduced into neuronal cells. Neurones harboring the A4V, G93A, G85R, and D90A mutants of PEP-1-SOD were more vulnerable to oxidative stress induced by paraquat than those harboring wild-type proteins. Moreover, neurones harboring the mutant SOD proteins had lower heat shock protein (Hsp) expression levels than those harboring wild-type SOD. The effects of the transduced SOD1 fusion proteins may provide an explanation for the association of SOD1 with FALS, and Hsps could be candidate agents for the treatment of ALS.

• BMB Reports
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• v.41 no.5
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• pp.408-413
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• 2008

Pyridoxal-5'-phosphate phosphatase (PLPP) catalyzes the dephosphorylation of pyridoxal-5'-phosphate (PLP). A human brain PLPP gene was fused with a PEP-1 peptide and produced a genetic in-frame PEP-1-PLPP fusion protein. The purified PEP-1-PLPP fusion protein was efficiently transduced into PC12 cells in a time- and dose-dependent manner when added exogenously to culture media. Once inside the cells, the transduced PEP-1-PLPP fusion protein was stable for 36 h. The concentration of PLP was markedly decreased by the addition of exogenous PEP-1-PLPP to media pretreated with the vitamin $B_6$ precursors; pyridoxine, pyridoxal kinase and pyridoxine-5'-phosphate oxidase into cells. The results suggest that the transduction of the PEP-1-PLPP fusion protein can be one mode of PLP level regulation, and to replenish this enzyme in the various neurological disorders related to vitamin $B_6$.

• Journal of Trauma and Injury
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• v.26 no.2
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• pp.47-52
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• 2013

Purpose: Injury severity score (ISS), a widely used scoring system, is used to define the severity of trauma in multiple-trauma patients. Nevertheless, ISS cut-off value for predicting the outcome of multiple-trauma patients has not been confirmed. Thus, this study was performed to determine the more useful method for predicting the outcome for multiple-trauma patients: the ISS or the number of anatomical Abbreviated injury scale (AIS) injury regions. Methods: for 195 consecutive patients who a regional emergency medical center, we analyzed the ISS and the number of anatomical AIS injury region. The patients were divided into four groups based on the ISS and the number of anatomical AIS regions. We compared intensive-care-unit (ICU) admission days and hospitalization days and ICU stay ratio (ICU admission days/hospitalization days) between the four groups. Results: In the groups with an ISS more than 17, the results were not significantly different statistically the group with 2 anatomical AIS injury regions and more than 3 anatomical AIS injury regions. Also, in the group with an ISS of 17 or less, the results were the same as those for patients with an ISS more than 17 (p>0.05). Among the patients with 2 anatomical AIS injury regions, patients with an ISS more than 17 patients had more ICU admission days and a higher ICU stay ratio than patients with an ISS 17 or less. Also, Among the patients with 3 anatomical AIS injury regions, the results were the same as those for patients with 2 anatomical AIS injury regions. Conclusion: Patients with high ISS, regardless of the number of anatomical AIS injury regions had significantly longer ICU stays and higher ICU admission ratio. Thus, the ISS may be a better method than the number of anatomical AIS injury regions for predicting the outcomes for multiple-trauma patients.