• Title/Summary/Keyword: Yangkyuksanwhatang

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Effects of Soyangin Yangkyuksanwhatang(少陽人凉膈散火湯), Soyangin Yangkyuksanwhatang Indongduengjigolpitang(忍冬藤地骨皮湯) and Sookjiwhanggosamtang(熟地黃苦蔘湯) on the Alloxan-Induced diabetic Rats (소양인(少陽人) 양격산화탕(凉膈散火湯)과 인동등지골피탕(忍冬藤地骨皮湯) 및 숙지황고삼탕(熟地黃苦蔘湯)이 Alloxan 투여(投與) 고혈당(高血糖) 백서(白鼠)에 미치는 영향(影響))

  • Choi, byung-ill;Song, Il-byung
    • Journal of Sasang Constitutional Medicine
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    • v.10 no.2
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    • pp.513-532
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    • 1998
  • In order to investigate the effect of the Soyangin Yangkyuksanwhatang, Indongduengjigolpitang and Sookjiwhanggosamtang that are the model prescriptions for diabetic soyangin. The contents of serum glucose, insulin, total triglyceride and urine glucose, ketone-body and urine volumn and body-weights were mesured on the Alloxan-Induced diabetic Rats. The following results have been measured. 1. Yangkyuksanwhatang, Indonduengjigolpitang and Sookjiwhanggosamtang showed significant decreases on the serum glucose and particulruy Sookjiwhanggosamtang decreased significantly. 2. The contents of serum insulin on the Alloxan-Induced diabetic Rats comparing with normal group were increased in Yangkyuksanwhatang and Indongduengjigolpitang with no significance but Sookjiwhanggosamtang showed a significant increase on the serum insulin. 3. The contents of serum triglyceride were decreased in three groups, but Indongduengjigolpitang showed the significant decrease and others did not. 4. The contents of serum total cholesterol were signicantly decreased In indongduengjigolpitang but Yangkyuksanwhatang and Sookjiwhanggosamtang did not. 5. The contents of urine glucose simillary decreased in three groups. 6. The contents of urine ketone-body were not changed comparing with control group in Yangkyuksanwhatang and Indongduengjigolpitang groups, but Sookjiwhanggosamtang group showed some increase. 7. The urine volume were significantly decreased in Yangkyuksanwhatang, but Indongduengjigolpitang and Sookjiwhanggosamtang showed the decrease of urine volume with no significance. 8. Body weights were regained comparing with control group, but only Indongduengjigolpitang showed significant increase. According to the above results, Yangkyuksanwhatang, Indongduengjigolpitang and Sookjiwhanggosamtang had the effect for hyperglycemia, particulary Indongduengjigolpitang was assumed as having the effect for hyperlipemia and weight-loss induced by D. M.. Therefore, by this experiments it can be concluded that Yangkyuksanwhatang, indongduengjigolpitang and Sookjiwhanggosamtang recorded in "DongYi Soose Bowon" have the effect for soyangin diabetics.

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Antithrombotic Activities of Chungpesagantang, Sunghyangjunggisan and Yangkyuksanwhatang

  • Park, Eun-Kyung;Han, Yeo-Ock;Kim, Jong-Mi;Han, Myung-Joo;Kim, Dong-Hyun
    • Natural Product Sciences
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    • v.8 no.4
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    • pp.173-176
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    • 2002
  • The possibility of Chungpesagantang, Sunghyangjunggisan and Yangkyuksanwhatang, which have been recommended for stroke patients with constipation in traditional Korean clinics, was evaluated as a novel antithrombotic agent. Chungpesagantang potently inhibited ADP- and collagen-induced rat platelet aggregation in vitro, but Sunghyangjunggisan and Yangkyuksanwhatang did not inhibit it. However, all tested herbal formulae inhibited in vivo ADP- and collagen-induced rat platelet aggregation and extended the bleeding time of mice tails. All these herbal formulae did not affect certain plasma clotting times such as APTT, PT and TT. Among these herbal formulae, Chungpesagantang showed significant protection against death due to pulmonary thrombosis in mice. Based on these findings, these herbal formulae should prevent thrombosis and cardiovascular diseases such as myocardial infraction stroke, and arteriosclerosis.

A clinical study of Soyangin Yangkyuksanwhatang (양격산화탕(凉膈散火湯) 활용(活用)에 대(對)한 임상적(臨床的) 연구(硏究))

  • Park, Seong-sik;Kim, Ji-yong;Choi, Jae-young
    • Journal of Sasang Constitutional Medicine
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    • v.10 no.2
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    • pp.455-471
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    • 1998
  • Background and Purpose : We intended to be helpful to understand constitutional symptoms of a disease and an application of the prescription through a clinical study of Soyangin Yangkyuksanwhatang. Methods : We studied 65 patients(40 men and 25 women) treated with Soyangin Yangkyuksanwhatang in constitutional clinic of Dongguk Pundang Oriental Hospital. And then we investigated the characteristics of Yangkyuksanwhatang treated patients, remedial values, onset of action and side effects. Results: Soyangin Yangkyuksanwhatang was used in all age groups both men and women. There were 37 kinds of chief complaints including chest discomfort, numbness of hands and feet, motor disturbance and skin disease etc. The distributions of remedial values were slightly improved(58.5%), much improved(12.3%), no improved(29.3%) and there was no aggravated patient. Using the prescription, mostly I prescribed only Soyangin Yangkyuksanwhatang without any changing, and added some herbs to the prescription according to the symptoms of a disease. Soyangin Yangkyuksanwhatang was affected in remedial values by the addition and subtraction of herbs. The onset of action in young age group was shorter than old age group. Side effects were palpitation, abdominal pain and indigestion etc.

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Studies on Efficacy of Combined Preparation of Crude Drugs(XXIII) -Analgesic, Anticonvulsive, Sedative, Antipyretic Actions of Yangkyuksanwhatang and its Effects on Isolated Ileum and Blood Vessel- (생약복합제제(生藥複合製劑)의 약효연구(藥效硏究) (제13보)(第13報) -양격산화탕(凉膈散火湯)의 진통(鎭痛) 항경련(抗痙攣) 진정(鎭靜) 해열(解熱) 작용(作用) 및 적출(摘出) 장관(腸管) 및 혈관(血管)에 미치는 영향(影響)-)

  • Hong, Nam-Doo;Kim, Jong-Woo;Song, Il-Byung;Won, Do-Hee;Kim, Nam-Jae;Kim, Jin-Sung
    • Journal of Pharmaceutical Investigation
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    • v.15 no.2
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    • pp.63-72
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    • 1985
  • Analgesic, anticonvulsive, sedative and antipyretic actions of Yangkyuksanwhatang which is composed of nine crude drugs including Rehmanniae Radix, and its effects on isolated ileum and blood vessel were investigated. The results of the studies were summerized as follows; 1. Analgesic and antipyretic effects were observed. 2. Suppressive actions were not shown on the convulsion induced by strychnine, but significant effects were noted on the convulsion induced by picrotoxin. 3. A prolongation of anesthetic time induced by pentobarbital sodium was significantly observed. 4. Relaxing actions were noted on the ileum of mice, and also, same effects were recognized on the contraction of the ileum due to acetylcholine chloride and barium chloride. 5. The expansion of blood vessels by relaxation of smooth muscle and hypotensive effects were noted.

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