• 사상체질의학회지
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• 제14권3호
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• pp.85-96
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• 2002

The purpose of this study is to examine the effects of sasang constitutional herbal extracts such as Yangkyuksanhwatang(YST) on EKG. For this purpose, 3 hospitalized Soyangin patients having heart disease history was selected. and changes of the symptoms and EKGs was investigated. We measured and observed EKG changes of before YST medication and after medication. The results of these experiments were as follows. 1. The activity of HR, PR, QRS was decreased on EKG2 comparison to EKG1 after Yangkyuksanhwatang(YST) medication 2. QT, QTC interval was prolonged after YST medication 3. RR time was prolonged after YST medication 4. The voltage of Q wave was decreased after YST medication From the above results, it is suggested that Yangkyuksanhwatang(YST) have influenced on EKG.

• 사상체질의학회지
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• 제12권2호
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• pp.153-161
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• 2000

1. Purpose This studies the regulatory effect of cytokine production in Soyangin patients with cerebral infarction by Yangkyuksanhwatang. 2 Method ELISA 3. Result & Conclusion Yangkyuksanhwatang(YST) is a prescription for the cerebral infarction (CI) patients of Soyangin according to Sasang constitution philosophy. Soyangin patients with CI were treated with YST during the acute stage. Clinical signs of CI disappeared markedly in about 2 to 4 weeks after oral administration of YST in all patients. The mean interleukin (IL)-2 plasma levels were slightly lower in the patients with CI than in the normal groups, whereas the mean IL-4, IL-6 and IgE levels were significantly higher in the patients. There were no significant differences in interferon- ${\gamma}$ (IFN- ${\gamma}$ ) levels between the groups. Serum IFN- ${\gamma}$ and IL-2 levels derived from T helper (Th)1 cells were elevated significantly in the patients with CI by YST administration. Significant reduced plasma levels of IL-4 and IL-6 derived from Th2 cells and IgE were observed in the patients treated with YST. During the period of YST administration, there were no other adverse effects. The data indicate that YST has a good CI treatment effect, and that its action may be due to regulation of cytokine production.

• 사상체질의학회지
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• 제11권2호
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• pp.391-395
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• 1999

본인은 소양인 환자의 태음인 오치 2증례를 통해 소양인에게 태음인처방(열다한소탕과 같은 하제의 성격)을 주었을 때 어떤 결과가 나오는지 살펴보게 되었다. 이러한 경우에 대해 비슷한 임상적 예와 이론을 상한론의 조문에서 또한 찾아볼 수 있었다. 이를 통해 소양인에게 열다한소탕과 같은 성격의 태음인 처방을 주었을 때 소양인리병 흉격열증이나 소양인 표병 결흉증과 같은 양상이 나올 것이라는 가정을 가질 수 있었다.

• 사상체질의학회지
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• 제14권2호
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• pp.106-114
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• 2002

The etiology of spontaneous intracerebral hematoma is aneurysmal rupture, arteriovenous malfomation, brain rumor, blood dyscrasia, cerebral infaction, cerebra inflammatory vascular disease, hypertension, and unknown causes. And the primary intracerebral hematoma is caused by unknown causes including hypertension. The clinical diagnosis of intracerebral hematoma, size, location, ventricular penetration, and evolution of brain parenchyme by hemorrhage are confirmed by CT scan. The authors have experienced 1 case of spontaneous intracerebral hematoma confirmed by CT scan. We have diagnosed the patient as Soyangin and treated by east integrated therapy. We classified this case as Soyangin-liyoiljung(少陽人裏熱證) and prescribed Yangkyuksanhwatang' Jihwangbaekhotang Hyungbangsabaeksan to the principle of Cheongyangsangsung(淸陽上升). In the result, we had the improvement of the symptoms. This report discribed the process and contents about the way the patient was cured.

• 사상체질의학회지
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• 제14권2호
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• pp.69-77
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• 2002

Purpose: Atopic dermatitis, which is one the prevalent allergic diseases in toddlers and adolescent population, has not been treated with Sasang Constitutional Medicine due to the limitation of constitution differentiation in children. This study was aimed to examine the effect of treatment for atopic dermatitis with Sasang Constitutional Medicine. Method: Forty-three patients over age 3 who were diagnosed with atopic dermatitis by the criteria of Hanifin and Rajka were participated in this study from August, 2001 thru May, 2002 at the Pohang Oriental Medicine Hospital, Kyungsan University. Result: 1. Soyangin showed the highest proportion of 79% of the sample. 2. The symptom of the disease by patients' constitution according to the degree of affected skin and itching was severe in Soyangin, and mild in Soeumin 3. For treatment 9 kinds of prescription regimen were given; Yangkyuksanhwatang was mostly used for Soyangin followed by Hyungbangsabaksan. Hayngsayangwetang and Galgunhaegitang were prescribed for Soeumin and Taeumin, respectively. 4. The treatment effect was found in 84% (n=36) of the patients markedly. Six out of seven who showed no progress were Soyangin. Conclusion: The treatment based on the constitution differentiation and prescription of the Sasang Constitutional Medicine was effective for the symptom alleviation in a short term period in atopic dermatitis. Further clinical study is needed to prove the effect of Sasang Constitutional Medicine in a larger sample and various diseases.

• 사상체질의학회지
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• 제11권2호
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• pp.361-376
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• 1999

1. 연구배경(硏究背景) 및 목적(目的) 피부질환의 가장 흔한 증상 가운데 하나인 소양증(瘙痒症)에 대한 임상적(臨床的) 연구(硏究)를 시행하여 소양증의 특성을 정확히 파악하고 치료에 도움을 주고자 하였다. 2. 연구방법(硏究方法) 1997년 11월부터 1999년 9월까지 1년 10개월간 동국대학교 분당한방병원 사상체질과에 소양증(瘙痒症)을 주소로 하여 내원한 외래환자 가운데 2회 이상 내원하여 치료경과가 확인된 59영(남자 35명, 여자 24명)을 대상으로 소양증 환자의 일반적(一般的) 특성(特性), 소양증(瘙痒症)의 양태(樣態), 치료특성(治療特性), 치료효과(治療效果)를 조사하고 분석하였다. 3. 연구결과(硏究結果) 소양증은 남자가 여자보다 많았으며 20대와 30대에서 많았다. 소양증의 이환기간(罹患其間)은 1개월에서 1년 미만인 경우가 많았고, 양방(洋方) 의료기관을 거쳐서 오는 경우가 대부분이었다. 소양증은 주야(晝夜)구분 없이 심한 경우가 많았고, 소양증 환자의 전신증상(全身症狀)은 전체적으로 대변이상(大便異常)이 많았으며, 사상체질별로는 소음인(少陰人)에서는 소화불량(消化不良)과 수면장애(睡眠障碍)가 많았고, 소양인(少陽人)에서는 대변이상(大便異常)과 설태이상(舌苔異常)이 많았으며, 태음인(太陰人)에서는 설태이상(舌苔異常)과 한출이상(汗出異常)이 많았다. 소양증에 많이 사용된 처방은 곽향정기산(藿香正氣散), 양격산화탕(凉膈散火湯), 청심연자탕(淸心蓮子湯) 등이었고, 치료효과(治療效果)의 분포는 호전(好戰)이 61.0%. 비호전(非好戰)이 39.0%로 나타났다. 치료효과는 연령이 30세 이상인 경우가 20세 이하인 경우보다 유의하게 호전되었으며. 이환기간이 1년 미만으로 짧은 경우가 1년 이상으로 긴 경우보다 유의하게 호전되었으며, 양방치료를 않거나, 지속적으로 치료 중인 경우가 간헐적으로 치료중인 경우보다 유의하게 호전되었으며, 소양증의 정도가 심한 경우가 약한 경우보다 유의하게 호전되었다.