• Title/Summary/Keyword: X-RD

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Control Thresholds for Managing Common Cutworm, Spodoptera litura (Fabricius) (Lepidoptera: Noctuidae) on Chinese Cabbage (배추에서 담배거세미나방(Spodoptera litura)의 요방제 수준 설정)

  • Choi, Duck-Soo;Kim, Do-Ik;Kim, Seon-Gon;Ko, Suk-Ju;Kang, Beom-Ryong;Kim, Sang-Soo
    • Korean journal of applied entomology
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    • v.50 no.3
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    • pp.215-220
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    • 2011
  • This study aimed to estimate control thresholds for managing common cutworm, Spodoptera litura Faricius (Lepidoptera: Noctuidae) at different larval densities and growth stages of Chinese cabbage in field conditions. The percent yield reduction (Y) of Chinese cabbage infested by different densities of S. litura (X, no. of larvae/100 plants) for three weeks were estimated by Y=-21.85X+1300 (R2=0.997) 5 days after transplanting and Y=-12.1X+1382 (R2=0.998) 20 days after transplanting. Based on the relationships between the densities of S. litura larvae and the yield index of chinese cabbage, the number of larvae (2nd to 3rd instar) which caused 5% loss of yield was estimated as 2.9/100 plants 5 days after transplanting, and 5.6/100 plants 20 days after transplanting.

Comparative Study of Korean Mistletoe Lectin and Bee Venom on the Anti-Cancer Effect and Its Mechanisms of Action in Hepatocellular Carcinoma Cells (상기생과 봉독이 간암 세포주 Hep G2에 대해 미치는 항암 기전 비교)

  • Kim, Sung-Uk;Kim, Bo-Ram;Heo, Kyung;Lim, Seong-Woo
    • The Journal of Internal Korean Medicine
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    • v.30 no.4
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    • pp.845-857
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    • 2009
  • Background and Objectives : Korean mistletoe lectin (Viscum album coloratum agglutinin, VCA) and bee venom (BV) have been reported to induce apoptosis in various cancer cell lines in vitro and to show antitumor activity against a variety of tumors in animal models. However, the comparative effect of VCA and BV on the anti-cancer effect and mechanisms of action has not been determined. In this study, the effect in a human hepatocellular carcinoma cell line, Hep G2 cells, was examined. Methods : Cytotoxic effects of VCA and BV on Hep G2 cells were determined by 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay in litro. The apoptotic cell death was then confirmed by propidium iodide staining and DNA fragmentation analysis. The mechanisms of action were examined by the expression of anti-apoptotic proteins and activation of mitogen-activated protein kinases. The involvement of kinase was examined in VCA or BV-induced apoptosis by using kinase inhibitors. Results : VCA and BV killed Hep G2 cells in a time and dose-dependent manner. Treatment of Hep G2 cells with VCA activated poly (ADP-ribose) polymerase-1 (PARP-1) known as a marker of apoptosis, and mitogen-activated protein kinases signaling pathways including MAPK/ERK, p38 MAPK and JNK. BV also activated PARP-1, MAPK/ERK. and p38 MAPK but not JNK. The expression level of anti-apoptotic molecule, Bcl-X, was decreased by VCA treatment but not by BV. Finally, the phosphorylation level of ERM proteins involved in the cytoskeleton homeostasis was decreased by both stimuli. VCA-induced apoptosis was partially inhibited by in the presence of JNK and p38 inhibitor, but BV only by p38 inhibitor. Conclusions : VCA-induced apoptosis is dependent on the activation of p38 and JNK. while BV-induced apoptosis is mediated by p38 activation in Hep G2 cells.

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A STATISTICAL STUDY OF THE MAXILLOFACIAL DISEASES BY RADIOGRAMS (X-선상에 이한 악안면질환의 통계학적 고찰)

  • Chung Yoo Taik
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.4 no.1
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    • pp.45-57
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    • 1974
  • This report based on 300 cases of serious diseases in maxillofacial region by radiograms seen at the department of dental radiodontics, infirmary school of dentistry, Kyung Hee University from October 1971 to August 1974. The maxillofacial diseases were analysed upon the following items, such as 1) the frequency of dominant diseases, 2) sex-ratio of male to female, 3) predominant region of diseases, 4) comparison with the age, 5) the incidence of diseases in relative to the individual teeth. The results were obtained as follows. 1) Among the total of 300 cases of the patients, the frequency of dominant diseases of patients were fractures of facial bone (44.3±2.87%), inflammatory diseases (22.7±2.39%), cysts (11.1±1.62%), tumors (10.7±1.77%), maxillary sinusitis (7.9±1.56%), temporomandibular joint disorders(3.3±1.05%) in the order. 2) The ex-ratio of male to female in occurence of jaw fractures were 7.3:1, temporomandibular joint disorders were 2.1:1, inflammatory diseases were 1.8:1, maxillary sinusitis were 1.7:1, but tumors were equal to 1:1, while cysts were 1:1.2 in sex difference. 3) The predominant region of mandibular fractures were symphysis(17.3±3.27%), canine region (15.0±3.09%), and angle region (14.3:±3.04%) in the order. Inflammatory diseases were occured frequently in mandible and it's left side were a little dominant. Odontogenic cysts were observed frequently in maxilla, but regardless of right and left. Carcinomas were involved most frequently in maxilla, while sarcomas and ameloblastomas in mandible. Frequency of the maxillary sinusitis were dominant right side and molar area, also temporomandibular joint disorders were right side. 4) To study comparison with the age jaw fractures showed the highest ratio at the 2nd decade(32.3±4.06%), and 3rd decade (27.8±3.89%), 4th decade (19.6±3.44%), 6th decade (9.0±2.47%), 5th decade(6.0±2.06%), 1st decade (5.3±1.95%) in the order. But 7th decade were not involved entirely. Frequency of the inflammatory diseases were the highest in the age group of 3rd decade (28.0±5.44%), and those of cysts were 5th decade (24.2±7.22%), temporomandibular joint disorders were 3rd decade (60.0±15.49%). Tumors were occured frequently over the 4th decade especially malignint tumors over the 5th decade, but maxillary sinusitis were rearless of age except for 2nd decade. 5) About the incidence of diseases in relative to individual teeth, fractures of facial bone were most frequently involved the maxillary and mandibular anterior teeth, and mandibular 3rd molar region. Cysts were maxillary anterior region inflammatory diseases were mandibular molar region maxillary sinusitis were maxillary 1st molar, region but tumors were regardless of individual teeth.

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Treatment of Phalangeal Bone Defect Using Autologous Stromal Vascular Fraction from Lipoaspirated Tissue (자가기질혈관분획을 이용한 수지골 결손 환자의 치료)

  • Jeong, Tae-Won;Ji, Yi-Hwa;Kim, Deok-Woo;Dhong, Eun-Sang;Yoon, Eul-Sik
    • Archives of Plastic Surgery
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    • v.38 no.4
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    • pp.438-444
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    • 2011
  • Purpose: Adipose-derived stromal cells (ASCs) are readily harvested from lipoaspirated tissue or subcutaneous adipose tissue fragments. The stromal vascular fraction (SVF) is a heterogeneous set of cell populations that surround and support adipose tissue, which includes the stromal cells, ASCs, that have the ability to differentiate into cells of several lineages and contains cells from the microvasculature. The mechanisms that drive the ASCs into the osteoblast lineage are still not clear, but the process has been more extensively studied in bone marrow stromal cells. The purpose of this study was to investigate the osteogenic capacity of adipose derived SVF cells and evaluate bone formation following implantation of SVF cells into the bone defect of human phalanx. Methods: Case 1 a 43-year-old male was wounded while using a press machine. After first operation, segmental bone defects of the left 3rd and 4th middle phalanx occurred. At first we injected the SVF cells combined with demineralized bone matrix (DBM) to defected 4th middle phalangeal bone lesion. We used P (L/DL)LA [Poly (70L-lactide-co-30DL-lactide) Co Polymer P (L/DL)LA] as a scaffold. Next, we implanted the SVF cells combined with DBM to repair left 3rd middle phalangeal bone defect in sequence. Case 2 was a 25-year-old man with crushing hand injury. Three months after the previous surgery, we implanted the SVF cells combined with DBM to restore right 3rd middle phalangeal bone defect by syringe injection. Radiographic images were taken at follow-up hospital visits and evaluated radiographically by means of computerized analysis of digital images. Results: The phalangeal bone defect was treated with autologous SVF cells isolated and applied in a single operative procedure in combination with DBM. The SVF cells were supported in place with mechanical fixation with a resorbable macroporous sheets acting as a soft tissue barrier. The radiographic appearance of the defect revealed a restoration to average bone density and stable position of pharyngeal bone. Densitometric evaluations for digital X-ray revealed improved bone densities in two cases with pharyngeal bone defects, that is, 65.2% for 4th finger of the case 1, 60.5% for 3rd finger of the case 1 and 60.1% for the case 2. Conclusion: This study demonstrated that adipose derived stromal vascular fraction cells have osteogenic potential in two clinical case studies. Thus, these reports show that cells from the SVF cells have potential in many areas of clinical cell therapy and regenerative medicine, albeit a lot of work is yet to be done.

Relation of the Fertility and Grain Weight of Wheat and Barley to their Spike Differentiation and Development (대소맥에 있어서 소수 및 소화의 분화, 발육정도가 임성 및 립중에 미치는 영향)

  • 남윤일;하용웅
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.27 no.2
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    • pp.116-122
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    • 1982
  • In three diverse wheat and one barley cultivars were used to examine the relation of the spikelet and floret differentiation to fertility and an winter wheat Norin 61 was used to examine the spikelet size gradients in the mature ear in relation to their grain development. The greatest number of grains and florets per spikelet, and the heaviest grains occurred in the low-mid part of the ear. Within the spikelets, the 2nd grain from the base was heavier than the I st or the 3rd one. In this region, the fertility of the 1 st floret was 97%, the 2nd 93%, the 3rd 88%, and 4th floret was 15%. The fertility of the wheat and barley was closely related to spikelet and floret differentiation. Barley spikelets was fertile as their differentiation stage was X that is 25 days before heading. Wheat florets were fertile as their differentiation stage was X that is 15-20 days before heading. But, they were sterile or reduced in fertility if they were not reached to the stage X.

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Assessment of Allograft Function in Dog Single Lung Transplantation on CT (한국산 잡견에서 컴퓨터단층촬영을 이용한 이식폐의 기능평가)

  • 박기성;박창권
    • Journal of Chest Surgery
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    • v.30 no.11
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    • pp.1055-1061
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    • 1997
  • In the field of the experimental lung transplantation, we analyzed the CT findings of acute rejection, infection in the left single allotransplanted lung of adult mongrel dogs, and the CT findings were compared with the histological findings obtained by the lung biopsy Twenty two adult mongrel dogs were divided into two groups(Donor and recipient group). Donor lungs were flushed with LPDG(low pota,ilium dextral glucose) solution(n=4) or modified Euro-collins solution(n=7) and preserved over 20 hours with $10^{\circ}C(1$ case preservation for 4hours). After left single lung transplantation, the chest X-ray and sequential computed tomogram were performed with concomitant hemodynamic study and arterial blood gas analysis on immediate postoperative period, postoperative 3rd day and postoperative 7th day. Two of eleven transplanted lungs had acute rejection which was represented as moderate infiltration at immediate or 1st postoperative d y but became extensive infiltration at postoperative 3rd day on CT. There were showed one case of bronchopleural fistula, six cases of pneumonia and two cases of pulmonary infarction. In one rejection cases, the opacity of transplanted lung was improved by injection of methylprednisolone 500mg daily during 3 days. We concluded that CT was a useful noninvasive evaluation parameter after lung transplantation and the serial CT scan enabled early detection of acute rejection.

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X-Ray Scattering Studies on Molecular Structures of Star and Dendritic Polymers

  • Jin, Sang-Woo;Jin, Kyeong-Sik;Yoon, Jin-Hwan;Heo, Kyu-Young;Kim, Je-Han;Kim, Kwang-Woo;Ree, Moon-Hor;Higashihara, Tomoya;Watanabe, Takumi;Hirao, Akira
    • Macromolecular Research
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    • v.16 no.8
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    • pp.686-694
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    • 2008
  • We studied the molecular shapes and structural characteristics of a 33-armed, star polystyrene (PS-33A) and two $3^{rd}$-generation, dendrimer-like, star-branched poly(methyl methacrylate)s with different architectures (pMMA-G3a and PMMA-3Gb) and 32 end-branches under good solvent and theta ($\Theta$) solvent conditions by using synchrotron small angle X-ray scattering (SAXS). The SAXS analyses were used to determine the structural details of the star PS and dendrimer-like, star-branched PMMA polymers. PS-33A had a fuzzy-spherical shape, whereas PMMA-G3a and PMMA-G3b had fuzzy-ellipsoidal shapes of similar size, despite their different chemical architectures. The star PS polymer's arms were more extended than those of linear polystyrene. Furthermore, the branches of the dendrimer-like, star-branched polymers were more extended than those of the star PS polymer, despite having almost the same number of branches as PS-33A. The differences between the internal chain structures of these materials was attributed to their different chemical architectures.

Effect of Pore Structure Change on the Adsorption of NOM and THMs in Water Due to the Increase of Reactivation Number of Coal-based Activated Carbon (석탄계 활성탄의 재생 횟수 증가에 따른 세공 구조 변화가 수중의 NOM과 THM 흡착에 미치는 영향)

  • Son, Hee-Jong;Ryu, Dong-Choon;Jang, Seong-Ho
    • Journal of Korean Society of Environmental Engineers
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    • v.32 no.10
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    • pp.965-972
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    • 2010
  • The objective of this research was to evaluate for the changes of pore structures and adsorption capacities due to the increase the numbers of reactivation. The reactivated GAC had experienced three cycles of water treatment and thermal reactivation. The pore size distributions of virgin and reactivated GACs were very different. The virgin GAC was mostly microporous (< $15\;{\AA}$), with less mesopores ($20{\sim}100\;{\AA}$). The reactivated GACs was mostly mesoporous ($20{\sim}100\;{\AA}$), with less micropores (< $15\;{\AA}$). The specific surface area and total pore volume were reduced as the number of reactivation increased. The maximum adsorption capacity (X/M) of virgin GAC ($964.6\;{\mu}g/g$) for $CHCl_3$ was 2~3 times larger than 1st~3rd reactivated GAC ($255.6{\sim}399.5\;{\mu}g/g$). The maximum adsorption capacity (X/M) of virgin GAC (19.5 mg/g) for DOC (dissolved organic carbon) was equal to that of 1st~3rd reactivated GAC (18.0~18.7 mg/g).

Linear Characteristics Improvement of X-band TWT Amplifier for Satellite Communication with Linearizer (선형화기를 이용한 위성통신용 X-밴드 TWT 증폭기 선형특성 개선)

  • Choi, Won;Yang, Hong-Sun;Koo, Kyung-Heon
    • Journal of Advanced Navigation Technology
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    • v.15 no.5
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    • pp.789-794
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    • 2011
  • This paper has analyzed the AM-AM and AM-PM characteristics of 7.9 GHz~8.4 GHz X-band TWT used for satellite communication and improved its linearity and IMD performance by using linearizer. The TWT amplifier with the linearizer shows better AM-AM and AM-PM conversion, and has increased 1 dB compression point by 12.3 dB and $2.0^{\circ}/dB$ phase distortion point by 10 dB. The 3rd order intermodulation distortion, IMD3 is measured to be 37.0 dBc that is 16.2 dB improvement at the operating output. This paper also proposed the measurement method of IMD for high power amplifier, and that TWT amplifier can have better linearity and output power by compensating for the AM-PM characteristics.

Side Population Cell Level in Human Breast Cancer and Factors Related to Disease-free Survival

  • Jin, C.G.;Zou, T.N.;Li, J.;Chen, X.Q.;Liu, X.;Wang, Y.Y.;Wang, X.;Che, Y.H.;Wang, X.C.;Sriplung, Hutcha
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.3
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    • pp.991-996
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    • 2015
  • Side population (SP) cells have stem cell-like properties with a capacity for self-renewal and are resistant to chemotherapy and radiotherapy. Therefore the presence of SP cells in human breast cancer probably has prognostic value. Objective: To investigate the characteristics of SP cells and identify the relationship between the SP cells levels and clinico-pathological parameters of the breast tumor and disease-free survival (DFS) in breast cancer patients. Materials and Methods: A total of 122 eligible breast cancer patients were consecutively recruited from January 1, 2006 to December 31, 2007 at Yunnan Tumor Hospital. All eligible subjects received conventional treatment and were followed up for seven years. Predictors of recurrence and/or metastasis and DFS were analyzed using Cox regression analysis. Human breast cancer cells were also obtained from fresh human breast cancer tissue and cultured by the nucleic acid dye Hoechst33342 with Verapami. Flow cytometry (FCM) was employed to isolate the cells of SP and non-SP types. Results: In this study, SP cells were identified using flow cytometric analysis with Hoechst 33342 dye efflux. Adjusted for age, tumor size, lymph nodal status, histological grade, the Cox model showed a higher risk of recurrence and/or metastasis positively associated with the SP cell level (1.75, 1.02-2.98), as well as with axillary lymph node metastasis (2.99, 1.76-5.09), pathology invasiveness type (1.7, 1.14-2.55), and tumor volume doubling time (TVDT) (1.54, 1.01-2.36). Conclusions: The SP cell level is independently associated with tumor progression and clinical outcome after controlling for other pathological factors. The axillary lymph node status, TVDT and the status of non-invasive or invasive tumor independently predict the prognosis of breast cancer.