• Biomolecules & Therapeutics
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• 제9권1호
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• pp.1-6
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• 2001

Sa-Mul-Tang (Si-Wu-Tang, SMT), a kind of Chinese medicine, has been used for the hemato-deficient disease for hundreds of years. In this work, investigations on the anti-anemic activity of an aqueous extract of SMT were undertaken in order to find the pharmacological basis for the ethnomedical use of the formulation. Three kinds of Angelicase species, such as Angelica sinensis, Angelica acutiloba, and Angelica gigas, were used for preparing the water extracts of SMT. Anemic model rats were induced by the treatment of phenylhydrazine (40 mg/kg/day, i.p.) for 4 days. After the treatment of phenylhydrazine, rats were divided into several groups for their different treatment of three kinds of SMT. Red blood cell (RBC), hemoglobin (Hg), and hematocrit (Hct) were determined on the day 0, 3, 6, 10, 14 after the treatment of SMTs and erythrocytes deformabilities were also determined at the end of experiments. Oral administration of SMT (1g/kg/day) for 14 days did not ameliorate drug-induced anemic states evaluated by RBC counts, Hg contents, and Hct values. However, the erythrocyte deformabilities were improved in phenylhydrazine-treated group by the administragest that SMTs (p<0.05). Especially, these effects were high in the Angelica acutiloba group. These results suggest that SMTs have an ameliorative effect on blood rheology related to the blood stasis syndrome in oriental diagnostics not on the blood deficient states related to the anemic syndrome.

• Communications for Statistical Applications and Methods
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• 제15권1호
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• pp.77-86
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• 2008

본 논문에서는 비재생보증이 종료된 이후의 최적의 주기적인 예방보전정책을 제안한다. 비재생보증기간이 종료된 이후의 예방보전에 대하여 Wu와 Clements-Croome (2005)의 확률적 보전효과를 갖는 주기적인 예방보전모형을 가정한다. 시스템의 운영 기간 동안 사용자가 지불하여 야 할 비용들이 주어져 있을 때 단위시간당 기대비용을 결정한다. 또한, 구해진 단위시간당 기대비용을 최소화하는 최적의 예방보전 주기와 횟수를 결정하는 방법을 다룬다. 마지막으로 본 논문에서 제안된 예방보전정책을 설명하기 위해서 수치적 예를 살펴본다.

• Journal of Magnetics
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• 제16권2호
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• pp.169-172
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• 2011

This study reports an alternative method for measuring the magnetoresistance of unpatterned magnetic tunnel junctions similar to the current-in-plane tunneling (CIPT) method. Instead of using microprobes, a series of point contacts with different spacings are coated on the top surface of the junctions and R-H loops at various spacings are then measured by the usual four-point probe method. The values of magnetoresistance and resistance-area products can be obtained by fitting the measured data to the CIPT theoretical model. The test results of two types of junctions were highly similar to those obtained from standard CIPT tools. The proposed method may help to accelerate the process for evaluating the quality of magnetic tunnel junctions when commercial CIPT tools are not accessible.

• The Korean Journal of Physiology and Pharmacology
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• 제8권1호
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• pp.65-67
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• 2004

Dehydroevodiamine (DHED) is one of the bioactive components of the Chinese herbal medicine Wu-chu-yu-tang that has been shown to produce various pharmacological effects. In the present study, we investigated the pharmacokinetics of DHED after intravenous administration of two doses (2.5 and 5 mg/kg) in anesthetized rats. The plasma concentration of DHED was measured by reverse-phase high-performance liquid chromatography with UV detection. The mean area under the curve of the time-concentration profile was $21.9\;and\;53.9\;{\mu}g{\cdot}min/ml$ after the 2.5- and 5-mg/kg doses, respectively, and the volume of distribution was 1584.9 and 1580.6 ml following 2.5- and 5-mg/kg doses, respectively. Plasma concentration profiles versus time were compatible with a two-compartment model and first-order kinetics. The terminal elimination half-life was $91.8{\pm}16.6\;min$ and $78.7{\pm}11.9\;min$ in the dose of 2.5 and 5 mg/kg, respectively. This is the first report to study the pharmacokinetics of DHED in animals.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제13권9호
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• pp.4484-4501
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• 2019

In this paper, we put forward a delay-aware secure maximum distance separable (MDS) coded caching scheme to resist the eavesdropping attacks for device-to-device (D2D) content sharing by combining MDS coding with distributed caching. In particular, we define the average system delay to show the potential coupling of delay-content awareness, and learn the secure constraints to ensure that randomly distributed eavesdroppers cannot obtain enough encoded packets to recover their desired contents. Accordingly, we model such a caching problem as an optimization problem to minimize the average system delay with secure constraints and simplify it to its convex relaxation. Then we develop a delay-aware secure MDS coded caching algorithm to obtain the optimal caching policy. Extensive numerical results are provided to demonstrate the excellent performance of our proposed algorithm. Compared with the random coded caching scheme, uniform coded caching scheme and popularity based coded caching scheme, our proposed scheme has 3.7%, 3.3% and 0.7% performance gains, respectively.

• The Journal of Asian Finance, Economics and Business
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• 제8권3호
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• pp.69-77
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• 2021

The objective of this research is to explore the inconclusive theoretical and empirical association between institutional ownership and firm performance in the context of emerging Pakistani economy. The data set consists of all the non-financial firms listed on the Pakistan Stock Exchange (PSX). Annual data set covers the period ranging from 2010 to 2015. However, the econometric analysis does not include those firms with incomplete data. Thus the final data set comprised of an unbalanced panel of sample of 276 firms with 1231 firms years observations. Data related to the institutional ownership and other variables taken for the study were extracted through the annual financial reports of the firms. The research used Tobin's Q as a proxy of market measure of firm performance and tested the endogenous relation with institutional ownership through OLS and 2SLS approach. The study also applied Durbin-Wu-Hausman test to determine the endogeneity before analyzing the 2SLS model. The Durbin-Wu-Hausman Test (DWH) conform the endogenous link between institutional ownership and performance and vice versa. The results derived from 2SLS also confirm a highly significant relationship and two way direct proportional relationships between the institutional investment and corporate performance in the studied companies.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2002년도 가을 학술발표회 논문집
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• pp.605-610
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• 2002

The purpose of this study is to develop an analytic model which can describe the behavior or concrete compressive member strengthened by CFS(Carbon Fiber Sheet) with various cross-sectional shapes such as circular. square, and octagonal and various laminate angles. The failure criterion of laminated CFS is based on Tsai-Wu failure criterion. The stress strain model of confined concrete compressive member is based on an equation proposed by Mander. The effective lateral confining pressure is considered and modified according to various cross-sectional shapes. Octagonal cross-section shows the best results in the aspect of ductility, while circular does in compressive strengthening effects. In addition, [0/0/0/0] laminate in which the direction of fiber is parallel to the direction of principal stress shows the superior strength and ductility than other laminates. The analytic results show that strength and ductility of the analytic model depend on the cross-sectional shapes as well as the laminate angles.

• International Journal of Control, Automation, and Systems
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• 제4권2호
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• pp.139-145
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• 2006

A multi-variable Golden-Section adaptive controller is proposed for the tracking control of robotic manipulators with unknown dynamics. With a small sample time, the unknown dynamics of the robotic manipulator are denoted equivalently by a characteristic model of a 2-order multivariable time-varying difference equation. The coefficients of the characteristic model change slowly with time and some of their valuable characteristic relationships emerge. Based on the characteristic model, an adaptive algorithm with a simple form for the control of robotic manipulators is presented, which combines the multi-variable Golden-Section adaptive control law with the weighted least squares estimation method. Moreover, a compensation neural network law is incorporated into the designed controller to reduce the influence of the coefficients estimation error on the control performance. The results of the simulations indicate that the developed control scheme is effective in robotic manipulator control.

• Computers and Concrete
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• 제15권6호
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• pp.865-878
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• 2015

In order to construct a multiscale model for the compressive strength of plain concrete columns with circular cross section subjected to central longitudinal compressive load, a column failure mechanism is proposed based on the theory of internal instability. Based on an energy analysis, the multiscale model is developed to describe the failure process and predict the column's compressive strength. Comparisons of the predicted results with experimental data show that the proposed multiscale model can accurately represent both the compressive strength of the concrete columns with circular cross section, and the effect of column size on its strength.

• International Journal of Fuzzy Logic and Intelligent Systems
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• 제15권1호
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• pp.27-34
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• 2015

For a vision-based driver assistance system, unusual motion detection is one of the important means of preventing accidents. In this paper, we propose a real-time unusual-motion-detection model, which contains two stages: salient region detection and unusual motion detection. In the salient-region-detection stage, we present an improved temporal attention model. In the unusual-motion-detection stage, three kinds of factors, the speed, the motion direction, and the distance, are extracted for detecting unusual motion. A series of experimental results demonstrates the proposed method and shows the feasibility of the proposed model.