• Asian Pacific Journal of Cancer Prevention
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• v.15 no.5
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• pp.2083-2087
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• 2014

Colorectal cancers remain to be a common cause of cancer-related death. Early-onset cases as well as those of various ethnic origins have aggressive clinical features, the basis of which requires further exploration. The aim of this work was to examine the expression patterns of $p15^{INK4b}$ and SMAD4 in colorectal carcinoma of different ethnic origins. Fifty-five sporadic colorectal carcinoma of Egyptian origin, 25 of which were early onset, and 54 cancers of Finnish origin were immunohistochemically stained with antibodies against $p15^{INK4b}$ and SMAD4 proteins. Data were compared to the methylation status of the $p15^{INK4b}$ gene promotor. $p15^{INK4b}$ was totally lost or deficient (lost in ${\geq}50%$ of tumor cell) in 47/55 (85%) tumors of Egyptian origin as compared to 6/50 (12%) tumors of Finnish origin (p=7e-15). In the Egyptian cases with $p15^{INK4b}$ loss and available $p15^{INK4b}$ promotor methylation status, 89% of cases which lost $p15^{INK4b}$ expression were associated with $p15^{INK4b}$ gene promotor hypermethylation. SMAD4 was lost or deficient in 25/54 (46%) tumors of Egyptian origin and 28/48 (58%) tumors of Finnish origin. 22/54 (41%) Egyptian tumors showed combined loss/deficiency of both $p15^{INK4b}$ and SMAD4, while $p15^{INK4b}$ was selectively lost/deficient with positive SMAD4 expression in 24/54 (44%) tumors. Loss of $p15^{INK4b}$ was associated with older age at presentation (>50 years) in the Egyptian tumors (p=0.04). These data show for the first time that $p15^{INK4b}$ loss of expression marks a subset of colorectal cancers and ethnic origin may play a role in this selection. In a substantial number of cases, the loss was independent of SMAD4 but rather associated with $p15^{INK4b}$ gene promotor hypermethylation and old age which could be related to different environmental exposures.

• Journal of the Korean Society of Food Culture
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• v.3 no.1
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• pp.101-111
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• 1988

This study is to examine the origin of Andong sikhe and to introduce the making process of it. The following facts are found after consulting literature and doing field-work to find out the origin of Andong sikhe. Andong sikhe is a kind of so-sikhe develolped as a sweet beverage, the making process of which is to ferment the mixture of boiled rice, radish slices, and red pepper extract with malt liquid. So-sikhe is made by fermenting with malt the mixture of boiled rice, radish slices, red pepper powder and flavorings such as a shallot, a garlic and salt, and o-sikhe is made by adding fish to the ingredients used to make so-sikhe. So-sikhe is distributed on the coastal areas of the East Sea and the inland areas adjacent to them as o-sikhe is. It is presumed that so-sikhe was introduced to Korea by the same way as o-sikhe was introduced eastward from the regions around Thailand by sea. It is also presumed that Andong sikhe has been developed into its present type after the second half of the 18th century when red pepper was introduced to Korea and then widely used.

• Korean Journal of Head & Neck Oncology
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• v.28 no.1
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• pp.16-18
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• 2012

Ipsilateral tonsillectomy and panendoscopy-guided biopsy following imaging studies are considered a standard procedure in the search for a primary origin in patients with cervical metastatic carcinoma of unknown origin(MUO). However, many authors recommended bilateral tonsillectomy for the determination of the primary site of a MUO, because cervical metastasis may occur contralateral to tonsillar carcinoma. The authors attempted to address the clinical implications of using routine bilateral tonsillectomy to determine the primary site of MUOs based on a case report of cervical MUO that was finally diagnosed as a bilateral synchronous tonsillar carcinoma with cervical metastasis after a diagnostic work-up that included bilateral tonsillectomy.

• The Bulletin of The Korean Astronomical Society
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• v.38 no.1
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• pp.40.1-40.1
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• 2013

The HI ring serendipitously found in the Leo I galaxy group is unique in size in the Local Universe. It is ~200kpc in diameter with MHI~$1.67{\times}109M{\odot}$, surrounding a pair of early type galaxies M105 and NGC 3384. Its origin is still under debate whether it is the remnant of formation of a galaxy group (primordial) or formed from stripped material during galaxy-galaxy interaction (tidal origin). Intriguingly a number of dwarf galaxies have been identified along the gas ring (with or without optical counterpart). Various properties of these dwarf galaxies such as dark matter content, color, and/or metallicity will allow us to pin down the origin of this large scale HI ring. We have obtained a mosaicked CFHT MegaCam image and the EVLA HI cube of the large scale gas ring. In this work we present optical and gas properties of dwarf galaxies identified in the CFHT data.

• Safety and Health at Work
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• v.13 no.3
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• pp.261-262
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• 2022

Globally, it is estimated that the number of people living outside of their country of origin reached 281 million in 2020. The primary drive of those migrants when migrating voluntarily is work to increase their income and provide for their families left behind in their home countries. Those who migrate immediately seek means of income to sustain themselves through a perilous process as currently evidenced in the war in Ukraine and not too long ago in Syria and Venezuela. Unfortunately, migrant workers are globally known to predominantly be working in "4-D jobs"- dirty, dangerous, and difficult and discriminatory; the fourth D was recently added to acknowledge the discriminatory aspect and other social determinants of health migrant workers face in their host country while exposed to precarious work. Consequently, migrant workers are at considerable risk of work-related illnesses and injury but their health needs are critically overlooked in research and policy. Recognizing the UN Universal Declaration of Human Rights "Everyone has the right to work, to free choice of employment, to just and favourable conditions of work and to protection against unemployment", we cannot consider any human life - thus, the life of migrant workers - as dispensable through a structural discriminatory process that undervalues their occupational safety and health, livelihood and the contribution these workers bring to their host countries. This was seen during the preparation for the upcoming world cup in Qatar where migrant workers were exposed to a multiplicity of serious hazards including deadly heat hazards.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.42 no.2
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• pp.67-76
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• 2016

Dracunculiasis, otherwise known as guinea worm disease (GWD), is caused by infection with the nematode Dracunculus medinensis. This nematode is transmitted to humans exclusively via contaminated drinking water. The transmitting vectors are Cyclops copepods (water fleas), which are tiny free-swimming crustaceans usually found abundantly in freshwater ponds. Humans can acquire GWD by drinking water that contains vectors infected with guinea worm larvae. This disease is prevalent in some of the most deprived areas of the world, and no vaccine or medicine is currently available. International efforts to eradicate dracunculiasis began in the early 1980s. Most dentists and maxillofacial surgeons have neglected this kind of parasite infection. However, when performing charitable work in developing countries near the tropic lines or other regions where GWD is endemic, it is important to consider GWD in cases of swelling or tumors of unknown origin. This paper reviews the pathogenesis, epidemiology, clinical criteria, diagnostic criteria, treatment, and prevention of dracunculiasis. It also summarizes important factors for maxillofacial surgeons to consider.

• Transactions on Control, Automation and Systems Engineering
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• v.1 no.1
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• pp.62-68
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• 1999

FCM(Fuzzy Cognitive Map) is proposed for representing causal reasoning. Its structure allows systematic causal reasoning through a forward inference. Authors have already proposed a diagnostic system based on FCM to utilized to identify the true origin of fault by on-line pattern diagnosis. In FCM based fault diagnosis, Temporal Associative Memories (TAM) recall of FCM is utilized to identify the true origin of fault by on-line pattern match where predicted pattern sequences obtained from TAM recall of fault FCM models are compared with actually observed ones. In engineering processes, the propagation delays are induced by the dynamics of processes and may vary with variables involved. However, disregarding such propagation delays in FCM-based fault diagnosis may lead to erroneous diagnostic results. To solve the problem, a concept of FTCM(Fuzzy Time Cognitive Map) is introduced into FCM-based fault diagnosis in this work. Expecially, translation method of FTCM makes it possible to diagnose the fault for some discrete time. Simulation studies through two-tank system is carried out to verify the effectiveness of the proposed diagnostic scheme.

• Proceedings of the KSRS Conference
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• 1998.09a
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• pp.138-148
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• 1998

The aim of the work described in this paper is to develop a complex underground acoustic system which detects and localizes the origin of an underground hammering sound using an array of hydrophones located about loom underground. Three different methods for the sound localization will be presented, a time-delay method, a power-attenuation method and a hybrid method. In the time-delay method, the cross correlation of the signals received from the way of sensors is used to calculate the time delays between those signals. In the power-attenuation method, the powers of the received signals provide a measure of the distances of the source from the sensors. A new hybrid method has been developed for estimating the origin of the underground acoustic source by coupling both methods. The Nelder-Meade simplex search algorithm is then used to numerically estimate the position of the source in those methods. For each method the sound localization is carried out in three dimensions underground. The distance between the true and estimated origins of the source is in some cases less than 6m for a search area of radius 250m.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1995.04b
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• pp.220-226
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• 1995

A study on the spalling causes of work roll for cold rolling was performed in the cold rolling mill. Performance of work roll is dependent to a great extent on spalling sothat both roll manufactures and users show great interest in spalling. So this paper shows that spalling origin on the roll surface. As being well known, spalling mostlyoccurred due to developing fatigue fracture originated a crack on a roll. But such spalling can be prevented by proper roll maintenance, The spalling accidents have sharply decreased since 1981 because of the use of ultrasonic test to detect cracks on a roll.

• Journal of the Korean Home Economics Association
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• v.36 no.6
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• pp.13-26
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• 1998

This study investigated first, socio-economic, residential characteristics, and values for future life among low-income family wives. Second, the relationship of these characteristics to the wives' stress was examined. The subjects were 249 mothers of urban low-income families whose children attended one of 20 daycare centers located in poor residential areas. The instruments included Social Network Scale, Home Stress Scale, and Occupation Stress Scale. Data were analyzed by means, standard deviations, frequencies, paired t-tests, and the stepwise multiple regressions. We found that a majority of the mothers and their husbands had high school educational status and simple labor or sales/service work status. They lived in rental houses or apartments. Their families of origin were a major source of emotional supports. Insufficient income for non-employed wives, long work hours and lack of free time for employed wives were a major stress. Levels of the wives' home-related job-related stress were negatively related to their own and their hudsbands' work status.