• Title/Summary/Keyword: Wonkwang

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Geumeunyoungji-tang Inhibits Serum IgE Level in Mouse Dermatitis Induced by 2,4-dinitrofluorobenzene

  • Phan, Manh Hung;Jeon, Yong Deok;Kim, Min Cheol;Kim, Su Jin;Kim, Dae Seung;Kwon, Dong Yeul;Kim, Seong Hee;No, Seung Il;Kim, Hyun Jeong;Shin, Hyun Ji;Um, Jae Young;Hong, Seung Heon
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.28 no.2
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    • pp.217-222
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    • 2014
  • Lonicerae Flos containing formulation, Geumeumyoungji-tang (GYT), is an herbal prescription prepared using 5 different herbal drugs, namely, Lonicerae Flos, Ganoderma, Lactucae Herba, Xanthii Fructus, and Smilacis Rhizoma. This study was focused on the investigation of the pharmacological effects of GYT on allergic reactions. As the first step of the study, GYT was administered BALB/c mice which were sensitized by 2,4-dinitrofluorobenzene (DNFB). As the result GYT ameliorated dermatitis provoked by DNFB. The serum IgE level of the DNFB sensitized-mouse was significantly decreased when GYT was administered. In order to confirm the moderating effect of this prescription on allergic reaction, GYT was pretreated to human mast cells (HMC-1) before they were stimulated by phorbol-12-myristate 13-acetate plus calcium ionophore A23187 (PMACI). GYT suppressed secretion of inflammatory cytokines, interleukin (IL)-6 and IL-8, from HMC-1. Additionally, pretreatment of GYT showed regulating effect on COX-2 expression. Collectively, these findings provide insights into the pharmacological actions of GYT as a potential agent for treatment of allergic dermatitis.

Rhabdomyosarcoma of masticator space

  • Lee Wan;Lee Chang-Jin;Song Young-Han;Lee Byeong-Do
    • Imaging Science in Dentistry
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    • v.31 no.4
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    • pp.241-245
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    • 2001
  • A 16-year-old female was admitted to Wonkwang dental hospital with a chief complaint of painful ulceration on right buccal mucosa around mandibular 3rd molar area. Computed tomography and magnetic resonance imaging showed relative large soft tissue mass on the infratemporal fossa and masseter muscle region. By the feature of T1-weighted and T2-weighted of MR imaging, we suspected this mass as a kind of myogenic sarcoma. Histopathological and immunohistochemical studies established a definitive diagnosis of embryonal rhabdomyosarcoma. A review of the literature was also presented.

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Molecular discrimination of Panax ginseng species

  • Um, Jae-Young;Chung, Hwan-Suck;Kim, Hyun-Ju;Kim, Dae-Ki;Shim, Kyung-Shik;Lee, Kang-Yong;Kim, Jeong-Sook;Choi, Tae-Jin;Kim, Nam-Song;An, Nyeon-Hyoung;Lee, Kang-Min;Lee, Young-Mi;Kim, Jeong-Joong
    • Advances in Traditional Medicine
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    • v.1 no.2
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    • pp.52-58
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    • 2000
  • In order to develop convenient and reproducible methods for identification of ginseng drugs at a DNA level, RAPD (randomly amplified polymorphic DNA) and PCR-RFLP (PCR-Restriction fragment length polymorphism) analysis were applied within Panax species. To authenticate Panax ginseng betvyeen Chinese and Korean ginseng population, RAPD analysis were carried out using 20 mer-random primer. The similarity coefficients among the DNA of ginseng plants analyzed were low, ranging from 0.197 to 0.491. In addition, using PCR-RFLP analysis, very different fingerprints were obtained within Korean ginseng plants. These results suggest that these methods are able to authenticate the concerned Panax species. Broader application of this approach to authenticate other morphologically similar medicinal materials is rationalized.

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One case of Ramsay Hunt Syndrome which were treated with Daewhangchijahwangbaeg-byung(大黃梔子黃栢餠) and Yongdamsagantang-gami(龍膽瀉肝湯加味) (Ramsay Hunt Syndrome 환자를 대황치자황백병(大黃梔子黃栢餠)과 용담사간탕가미(龍膽瀉肝湯加味)로 치료한 치험1례)

  • Rhim Eun-Kyung;Lee Yun-Jae;Hwang Sang-Il;Baek Dong-Gi;Hong Seok-Hoon;Kim Song-Baeg;Yun Jong-Min;Yang Kyung-Suk;Choi Deok-Hwa;Shin Sun-Ho
    • The Journal of Internal Korean Medicine
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    • v.24 no.4_2
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    • pp.1007-1013
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    • 2003
  • Ramsay Hunt Syndrome is caused by infection of herpes zoster and associated with otalgia, herpetic eruptions, facial palsy, trigerminal pain and cochleovestibular dysfunction such as deafness, tinnitus, vertigo and so on. A 60-year old female, who has tinnitus, peripheral facial palsy, deafness, vertigo, postauricular pain and herpetic eschar, had been admitted to Wonkwang University Oriental Jeonju Medicine Hospital. We treated this patient with Daehwangchijahwangbaeg-byung and Yongdamsagantang-gami, and the patients showed improvement in the symptoms. So we describe the process and contents about the way the patient was cured.

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