• 제목/요약/키워드: Won Bang

검색결과 1,169건 처리시간 0.026초

Protective Effect of DA-9601, an Extract of Artemisiae Herba, against Naproxen-induced Gastric Damage in Arthritic Rats

  • Oh, Tae-Young;Ryu, Byong-Kweon;Ko, Jun-Il;Ahn, Byoung-Ok;Kim, Soon-Hoe;Kim, Won-Bae;Lee, Eun-Bang;Jin, Joo-Hyun;Hahm, Ki-Baik
    • Archives of Pharmacal Research
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    • 제20권5호
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    • pp.414-419
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    • 1997
  • Gastrointestinal irritation is the most frequent adverse effect in patients chronically taking nonsteroidal antiinflammatory drugs (NSAIDs) for the treatment of arthritic conditions. Gastroprotective effect of DA-9601, a new antiulcer agent from Artemisiae Herba extract, against NSAID was evaluated in a rat model of arthritis that is similar in many aspects to human rheumatoid arthritis. Daily oral dosing of naproxen (30 mg/kg), one of the most commonly used NSAID, induced apparent gastric lesions as well as a significant decrease in mucosal prostagiandin $E_2;(PGE_2)$ and prostagiandin F_${1{\alpha}}$$(PGF_{1{\alpha}})$ levels. Coadministration of DA-9601 prevents naproxen-induced mucosal injury and depletion of prostaglandins, in a dose-related manner. DA-9601 did not alter the antiinflammatory or analgesic effect of naproxen. The present results suggest that DA-9601 may be useful as a mucoprotectant against NSAIDs in clinical practice.

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Signal crosstalk between estrogen and peroxisome proliferator-activated receptor α on adiposity

  • Kim, Bang-Hyun;Won, Young-Suk;Kim, Dae-Yong;Kim, Bora;Kim, Eun-Young;Yoon, Mi-Jung;Oh, Goo-Taeg
    • BMB Reports
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    • 제42권2호
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    • pp.91-95
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    • 2009
  • Peroxisome proliferator-activated receptor $\alpha$ and estrogen are believed to be involved in metabolic changes leading to obesity. To test this relationship, we divided female wildtype and PPAR$\alpha$-deficient mice fed on a high fat diet into the following groups: mock-operated, ovariectomized (OVX), and $E_2$-treated. The visceral white adipose tissue and plasma cholesterol levels were increased significantly in wild type OVX and decreased in the $E_2$-treated group, but interestingly not in PPAR$\alpha$-deficient mice. The mRNA levels of lipoprotein lipase in adipose tissue were also increased in only wild type OVX and decreased significantly in $E_2$-treated mice. These novel results suggest the possibility of signaling crosstalk between PPAR$\alpha$ and $E_2$, causing obesity in vivo.

자동 비행 소형 무인 회전익항공기의 영상정보를 이용한 지상 이동물체 추적 연구 (Tracking of ground objects using image information for autonomous rotary unmanned aerial vehicles)

  • 강태화;백광열;목성훈;이원석;이동진;임승한;방효충
    • 한국항공우주학회지
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    • 제38권5호
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    • pp.490-498
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    • 2010
  • 본 논문에서는 소형 무인항공기에 영상 획득용 카메라를 장착하여 지상의 이동물체를 자동으로 추적하고 지상으로 영상정보를 지속적으로 전송하는 기술 및 관련 이론에 대한 연구를 다루고 있다. 본 연구에 사용된 회전익 무인항공기에는 소형 고성능의 영상획득 장치와 지상표적에 대한 식별 지향 자동추적 알고리즘이 탑재되었고 더욱 안정된 영상추적을 위해 영상 안정화 기법을 추가적으로 적용하였다. 최종적으로 모든 연구내용에 대해 비행시험을 수행하여 그 성능을 검증하였다.

Additional Effect of Zeolite Based on Bactericidal Activated Carbon Spheres with Enhanced Adsorption Effect and Higher Ignition Temperature

  • Zhu, Lei;Ye, Shu;Asghar, Ali;Bang, Seong-Ho;Oh, Won-Chun
    • 한국세라믹학회지
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    • 제53권1호
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    • pp.68-74
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    • 2016
  • In this study, the fabrication of zeolite combined activated carbon spherical samples was carried out as follows. Briefly, ZSM-5 zeolite and activated carbon were composed as main absorbent materials; by controlling the weight percentage of zeolite and binder materials, a series of spherical samples (AZP 4, 6, 8) were prepared. These spherical samples were characterized by BET, XRD, SEM, EDX, and pressure drop; benzene and iodine adsorption tests, bactericidal effect test, and ignition temperature test were also performed. The adsorption capability was found to depend on the BET surface area; the spherical samples AZP6 with high BET surface area of $1011m^2/g$ not only exhibited excellent removal effects for benzene (24.9%) and iodine (920mg/g) but also a good bactericidal effect. The enhanced ignition temperature may be attributed to the homogeneous dispersion conditions and the proper weight percentage ratio between zeolite and activated carbon.

일개 간호대학생의 학습유형과 자기주도적 학습 (Learning Style and Self-directed Learning of Nursing Students at One University)

  • 박지원;방경숙
    • Perspectives in Nursing Science
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    • 제7권1호
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    • pp.36-42
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    • 2010
  • Purpose: This study was done to identify the preferences for learning style and the degree of self-directed learning and influencing factors on it among nursing students working on a Bachelor of Science in a nursing program at Suwon. Methods: The study sample included 156 nursing students. A self-report questionnaire was used to assess the data. The data was analyzed using the SPSS/WIN program for descriptive and inferential statistics. Results: Most of the students preferred lectures rather than discussion or team projects as a teaching method. Students preferred deliberating, sensing, and the use of visuals for their learning style. In addition, they favored sequential learning over comprehensive learning. Self directed learning had better outcomes in 3rd and 4th year students than 1st or 2nd year students. Additionally, active learners and high achievers who had a good GPA showed higher self directed learning than the others. Conclusion: In order to maximize students' self-directed learning, study guidance will be necessary for freshmen and for some who experience difficulties in studying nursing courses. Nursing faculty members should pay close attention to facilitate student's self directed learning, and encourage more discussions in the classes.

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Modeling and Simulation of New Encoding Schemes for High-Speed UHF RFID Communication

  • Mo, Sang-Hyun;Bae, Ji-Hoon;Park, Chan-Won;Bang, Hyo-Chan;Park, Hyung Chul
    • ETRI Journal
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    • 제37권2호
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    • pp.241-250
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    • 2015
  • In this paper, we present novel high-speed transmission schemes for high-speed ultra-high frequency (UHF) radio-frequency identification communication. For high-speed communication, tags communicate with a reader using a high-speed Miller (HS-Miller) encoding and multiple antennas, and a reader communicates with tags using extended pulse-interval encoding (E-PIE). E-PIE can provide up to a two-fold faster data rate than conventional pulse-interval encoding. Using HS-Miller encoding and orthogonal multiplexing techniques, tags can achieve a two- to three-fold faster data rate than Miller encoding without degrading the demodulation performance at a reader. To verify the proposed transmission scheme, the MATLAB/Simulink model for high-speed backscatter based on an HS-Miller modulated subcarrier has been designed and simulated. The simulation results show that the proposed transmission scheme can achieve more than a 3 dB higher BER performance in comparison to a Miller modulated subcarrier.

접촉 오차 벡터를 이용한 비선형 변형체의 마찰접촉 해석 (Analysis of Frictional Contact Problems of Nonlinearly Deformable Bodies by Using Contact Error Vector)

  • Lee, Kisu;Kim, Bang-Won
    • 한국전산구조공학회논문집
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    • 제13권3호
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    • pp.305-319
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    • 2000
  • 본 논문에서는 대변형 비선형 변형체의 마찰 접촉 문제의 해법을 제시하였다. 접촉 가능 점에서 접촉조건을 접촉오차 벡터를 이용하여 표시하였으며, 이러한 접촉오차 벡터를 0으로 단조 감소시키기 위하여 반복계산법을 사용하였다. 각 반복계산은 2개의 단계로 구성되어 있다 : 첫 단계에서는 이미 구해진 해의 기하학적 모양에서 얻어지는 접촉오차 벡터를 이용하여 접촉력을 수정하고, 두 번째 단계에서는 첫 단계의 접촉력을 이용하여 평형방정식을 풀어서 변위 및 접촉오차를 계산하는 것이다. 본 반복계산법에 의하여 정확한 해를 얻을 수 있음을 설명하였으며, 강소성 막 및 비선형 탄성보를 사용하여 예제계산을 수행하였다.

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USN 기반의 도로주행 한계속도 지능적 조정 관리 시스템 연구 (A Basic study the Critical Speed Intelligent Control System of Based on USN Technology)

  • 조병완;방주식;이경수;황창연;박정훈;윤광원
    • 한국전산구조공학회:학술대회논문집
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    • 한국전산구조공학회 2009년도 정기 학술대회
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    • pp.475-478
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    • 2009
  • 안개가 교통사고를 유발시키는 원인을 살펴보면 운전자의 시거와 밀접한 관련이 있다. 짙은 안개가 발생하게 되면 돌발상황이 발생하였을 때 도로를 주행하던 차량이 안전하게 정지하기 위해서 필요한 최소 정지거리가 증가하게 되나 안개로 인한 시정이 나빠지게 되어서 사고발생확률이 높은 것이다. 또한 안전한 시거가 확보되지 않기 때문에 단독사고 발생 후 뒤따르던 차량이 전방을 확인하지 못한 상황에서 연쇄 충돌하게 되어 사고가 대형화된다. 이에 본 연구에서는 IT기술인 RFID와 USN을 이용하여 안개로 인한 시정거리에 따라 도로에 있는 과속카메라가 도로주행 한계속도를 자기 스스로 판단하여 자동조절하게 만들고 변경된 한계속도를 그 도로를 이용하는 차량운전자 휴대폰에 문자로 전송해주고 도로전광판에서도 정확하게 주행속도정보를 볼 수 있게 한다. 그리하여 도로주행 한계속도를 어기는 차량에는 범칙금을 부과하게 만든다. 본 연구를 통해 안개에 대한 교통사고의 위험을 줄이고 사회적 경제적으로 이익이 되도록 하기위해 기상상태 변화에 따른 USN 기반의 도로주행 한계속도 지능적 조정 관리시스템을 제안하고자 한다.

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Effects of Ankle Joint Position during Closed Kinetic Chain Exercise on Strength and Balance in Chronic Stroke

  • Kim, Ye-Eun;Bang, Dae-Hyouk;Shin, Won-Seob
    • The Journal of Korean Physical Therapy
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    • 제27권5호
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    • pp.345-350
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    • 2015
  • Purpose: This study was conducted to determine the effects of ankle joint position during closed kinetic chain (CKC) exercise on knee extensor strength and balance in patients with chronic stroke. Methods: Sixteen patients with chronic stroke participated in the study. Participants were randomly assigned to two groups: $15^{\circ}$ ankle joint plantar flexion group (n=8) and ankle joint neutral group (n=8) during CKC exercise. All participants underwent conventional physical therapy for 30 minutes. In addition, the experimental group ($15^{\circ}$ ankle joint plantar flexion group) and control group (ankle joint neutral group) participated in a 20-minute CKC exercise program. In both groups exercise was performed three times a week for four weeks. Outcomes including knee extensor strength and balance ability (Five times sit-to-stand test, Timed up and go test, and Balancia) were measured before and after exercise. Results: Significant differences in knee extensor strength and balance ability were observed between pre- and post-exercise in all groups (p<0.05). The improvement of knee extensor strength and dynamic balance was significantly higher in the experimental group than in the control group (p<0.05). Conclusion: These findings demonstrated that $15^{\circ}$ ankle joint plantar flexion during closed kinetic chain exercise is effective in improvement of knee extensor strength and dynamic balance in patients with chronic stroke.

주변 온도환경 변화에 따른 가스 인젝터 성능 변화에 대한 연구 (A Study on Performance Change of Gas Injector with Ambient Temperature Environment)

  • 김지윤;양정직;김진호;서지원;임종완
    • 한국가스학회지
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    • 제22권5호
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    • pp.18-23
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    • 2018
  • 본 연구에서는 CNG자동차 인젝터의 외부 환경온도에 따른 인젝터의 분사량을 분석하고자 한다. 특히 냉간 시동시와 같은 조건에서 분사량의 변화를 측정하여 저온환경이 가스인젝터 성능에 미치는 영향을 파악하고자 하며, 가스 인젝터 내부의 스프링 특성을 다르게 하여 실험을 진행 하였다. 실험 장치는 연료 공급부, 유량 측정부, 온도 챔버와 인젝터 제어부로 구성하였다. 실험결과를 통해 저온환경일수록 가스인젝터의 초기 분사량이 증가하였으며, 스프링길이 증가에 따른 니들의 열리는 시간(무효분사시간)이 지연됨을 확인하였다.