• Analytical Science and Technology
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• v.23 no.1
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• pp.60-67
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• 2010

A sensitive competitive heterogeneous bioluminescence immunoassay for serotonin was developed using photoprotein, aequorin as a label for the first time with the optimal assay conditions; especially, serotoninavidin conjugate was prepared by Mannich reaction and the synthetic process of serotonin-avidin conjugate was optimized by controlling the initial molar ratios of serotonin, formaldehyde and avidin (1:12,000:25). The developed bioluminescence immunoassay for serotonin showed good sensitivity (LOD of 0.68 ng/mL) with wide area of dynamic range ($5.0{\times}10^{-10}\;M\sim5.0{\times}10^{-7}\;M$). (cf. the range for serotonin in human blood serum is $151{\pm}45\;ng$/mL). In addition, cross-reactivity studies demonstrated that 5-methoxytryptamine showed some cross-reactivity (28.0%), whereas 3-methylindole, melatonin and 5-hydroxylindole-3-acetic acid showed no crossreactivity, and good recoveries were obtained in serum. Thus, this developed method provides a good tool to monitor serotonin in serum.

• The Korean Journal of Pesticide Science
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• v.4 no.4
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• pp.1-11
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• 2000

Since the chemical pesticides have been played a major role in crop protection practices during last 5 to 7 decades, social concerns on the pesticide residues in and on food commodities as well as environmental compartments have also growing with endless demands and interests. Most national regulation authorities over the world have paid a special attention on the data requirements for pesticide registration. In addition, even the registered pesticides also should follow the re-registration process, which meets today's guidelines and regulatory triggers and safety profiles. More recently, a defined interest in the international bodies has given to the global conservation program from the environmental contamination; these involves persistent organic pollutants (POPs), endocrine disrupting chemicals (EDs), biocides, etc.. In order to secure the food safety and keep our circumference sound, in-depth efforts getting information from global networks have perpetually to be given under relevant national agencies. At the same time, a nation-wide survey of the residues has also to be in operation to monitor the tendency of the toxicant in/on foods, feeds, and environmental segments. In final, the scientifically assessed results on safety should be opened to the public to provide the right-to-know for the consumers.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.6
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• pp.3429-3434
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• 2014

In the TFT-LCD(Thin Film Transistor-Liquid Crystal Display) panel manufacturing industry, SAMSUNG, a late entry, can catch up to leading first mover, SHARP. The changes the note, monitor, TV, and mobile markets in the TFT-LCD industry were studied using a system analysis method. In addition, the fast response time technology in SAMSUNG TFT-LCD technology was developed using the TRIZ method. For example, a new liquid crystal mixture of a wide view angle and fast response time were developed by doping a new high birefringence liquid crystal material in a base mixture using the contradiction method and su-field method of TRIZ. The response time of a new liquid crystal mixture was improved to approximately 60%(16.2ms with base LC mixture, 9.8ms with a new LC mixture).

• Proceedings of the KSRS Conference
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• v.1
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• pp.471-474
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• 2006

Several planktonic dinoflagellates, including Cochlodinium polykrikoides (p), are known to produce red tides responsible for massive fish kills and serious economic loss in turbid Northwest Pacific (Korean and neighboring) coastal waters during summer and fall seasons. In order to mitigate the impacts of these red tides, it is therefore very essential to detect, monitor and forecast their development and movement using currently available remote sensing technology because traditional ship-based field sampling and analysis are very limited in both space and temporal frequency. Satellite ocean color sensors, such as Sea-viewing Wide Field-of-view Sensor (SeaWiFS), are ideal instruments for detecting and monitoring these blooms because they provide relatively high frequency synoptic information over large areas. Thus, the present study attempts to evaluate the red tide index methods (previously developed by Ahn and Shanmugam et al., 2006) to identify potential areas of red tides from SeaWiFS imagery in Korean and neighboring waters. Findings revealed that the standard spectral ratio algorithms (OC4 and LCA) applied to SeaWiFS imagery yielded large errors in Chl retrievals for coastal areas, besides providing false information about the encountered red tides in the focused waters. On the contrary, the RI coupled with the standard spectral ratios yielded comprehensive information about various ranges of algal blooms, while RCA Chl showing a good agreement with in-situ data led to enhanced understanding of the spatial and temporal variability of the recent red tide occurrences in high scattering and absorbing waters off the Korean and Chinese coasts. The results suggest that the red tide index methods for the early detection of red tides blooms can provide state managers with accurate identification of the extent and location of blooms as a management tool.

• Journal of Radiation Protection and Research
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• v.20 no.1
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• pp.37-44
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• 1995

Since provisions on the technical criteria for personnel dosimetry was amended three years ago, several improvements in the technique of monitoring personnel doses by TLD have taken place, but for the photograpfic film as a personnel monitor, additional investigations should be carried out for its accuracy of dose estimates because of its wide use in the radiation involved industries. So, this paper describes the methods to develope dose evaluation algorithm for photographic film using ISO reference radiations by i) empirical formula, ii) degree-of-fit method, and iii) matrix approximation. These methods show a good agreement between irradiated and calculated dose within tolerance level represented in ANSI N13. 11, and can be used for the dose evaluation of X, ${\gamma}$ and/or radiation fields.

• Convergence Security Journal
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• v.12 no.6
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• pp.85-92
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• 2012

There are many software reliability models that are based on the times of occurrences of errors in the debugging of software. It is shown that it is possible to do asymptotic likelihood inference for software reliability models based on infinite failure model and non-homogeneous Poisson Processes (NHPP). For someone making a decision about when to market software, the conditional failure rate is an important variables. The finite failure model are used in a wide variety of practical situations. Their use in characterization problems, detection of outliers, linear estimation, study of system reliability, life-testing, survival analysis, data compression and many other fields can be seen from the many study. Statistical Process Control (SPC) can monitor the forecasting of software failure and there by contribute significantly to the improvement of software reliability. Control charts are widely used for software process control in the software industry. In this paper, we proposed a control mechanism based on NHPP using mean value function of log Poission, log-linear and Parto distribution.

• Journal of The Korean Association For Science Education
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• v.19 no.2
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• pp.173-184
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• 1999

The longitudinal trend of elementary and secondary students' science process skills were investigated to monitor the progress of science learning. Science process skill test, developedin an earlier study on developing a national science process skills assessment system,was revised and administered for the study on March, 1999. Subjects were sampled nation wide according to sex and region. The results of this assessments were compared to those administered on February, 1997. The results showed little difference on science process skills among elementary school students. However, secondary students showed marked increase in science process skills. More systematic and long-term research for assessing science process skills should be planned and performed periodically to provide empirical and foundational data for educational policy making.

• Spatial Information Research
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• v.19 no.3
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• pp.11-22
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• 2011

It is usual for the carbon dioxide emission to be calculated by official energy consumption statistics produced from a number of specialized industrial process such as refinery, power plant etc. The aim of this research was to evaluate potential of cadastral system in monitoring carbon dioxide emitted from land use. An empirical study for a cadastral category was conducted to demonstrate how a on-site measurement can be used to assist in estimating the carbon dioxide emission in terms of land use specific settings. The cadastral category based analysis made it possible to identify area-wide patterns of carbon dioxide emission, which cannot be acquired by traditional Government statistics. It was possible to identify successively increasing trends in the human-related parcels such as housing land while decreasing trends of carbon dioxide in sink parcels(eg. forest). The results indicate that the cadastral parcel could be used not only as a tool to monitor carbon dioxide emission, but also as an evidence to restrict initiation of development activities causing negative influence to carbon dioxide emission such as road construction. As a result, the research findings have established the new concept of "carbon dioxide emission monitoring based on cadastral category", proposed as an initial aim of this paper.

• The Korean Journal of Nuclear Medicine
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• v.36 no.1
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• pp.74-79
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• 2002

In addition to the well-established use of positron emission tomography (PET) in clinical oncology, novel roles for PET are rapidly emerging in the field of gene therapy. Methods for controlled gene delivery to living bodies, made available through advances in molecular biology, are currently being employed in animals for research purposes and in humans to treat diseases such as cancer. Although gene therapy is still in its early developmental stage, it is perceived that many serious illnesses could be treated successfully by the use of therapeutic gene delivery. A major challenge for the widespread use of human gene therapy is to achieve a controlled and effective delivery of foreign genes to target cells and subsequently, adequate levels of expression. As such, the availability of noninvasive imaging methods to accurately assess the location, duration, and level of transgene expression is critical for optimizing gene therapy strategies. Current endeavors to achieve this goal include methods that utilize magnetic resonance imaging, optical imaging, and nuclear imaging techniques. As for PET, reporter systems that utilize genes encoding enzymes that accumulate positron labeled substrates and those transcribing surface receptors that bind specific positron labeled ligands have been successfully developed. More recent advances in this area include improved reporter gene constructs and radiotracers, introduction of potential strategies to monitor endogenous gene expression, and human pilot studies evaluating the distribution and safety of reporter PET tracers. The remarkably rapid progress occurring in gene imaging technology indicates its importance and wide range of application. As such, gene imaging is likely to become a major and exciting new area for future application of PET technology.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.14 no.3
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• pp.1-6
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• 2014

Companies almost don't use an integrated control system using expensive network system in multimedia like TV and DID, despite IP-Broadcasting and communication equipment have expanded rapidly. The proposed integrated TCU(terminal control unit) is a control device that supports TV power On/Off check and remote control, power control reservation function, TV channel change, a variety of interface supports of input/output AC power & Lan port, RS-232C and IR using existing IP network after there is installed the Wake-on -Lan in the set-top box. The TCU can control and monitor 24 hours unlike existing low-cost control system RF method. In existing control equipment markets without expandability and low price, the TCU development including 24 hours monitoring and automatic control functions is expected to secure a wide range of companies.