• 제목/요약/키워드: White matter

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초급성 허혈성 뇌졸중 환자에서 관류자기공명영상의 정량적 평가: 1.5 T와 3.0 T 기기 비교 (Quantitative Evaluation of Perfusion Magnetic Resonance Imaging in Hyper-acute Ischemic Stroke Patients: Comparison with 1.5 T and 3.0 T Units)

  • 구은회;문일봉;동경래
    • 방사선산업학회지
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    • 제10권4호
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    • pp.193-198
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    • 2016
  • Perfusion magnetic resonance image of biological mechanism are independent of magnetic field strength in hyper acute ischemic stroke. 3.0 T magnetic field, however, does affect the SNRs (signal to noise ratio) and artifacts of PMRI (perfusion magnetic resonance image), which basically will influence the quantitative of PMRI. In this study, the effects of field strength on PMRI are analyzed. The effects of the diseases also are discussed. PMRI in WM(white matter), GM (gray matter), hyper acute ischemic stroke were companied with 1.5 T and 3.0 T on SNR. PMRI also was compared to the SI difference after setting ROI(region of interest) in left and right side of the brain. In conclusion, the SNRs and SI of the 3.0 T PMRI showed higher than those at 1.5 T. In summary, PMRI studies at 3.0 T is provided significantly improved perfusion evaluation when comparing with 1.5 T.

Festulolium braunii (Festuca pratensis Huds. × Lolium multiflorum Lam.)의 혼파유형이 목초의 건물수량과 품질에 미치는 영향 (Effect of Mixture Types with Festulolium braunii (Festuca pratensis Huds. × Lolium multiflorum Lam.) on Dry Matter Yield and Quality)

  • 인인덕;이형석
    • 한국초지조사료학회지
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    • 제18권4호
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    • pp.311-316
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    • 1998
  • 본 시험은 충남대학교 농과대학 초지시험포장에 1995년 9월부터 1998년 5월까지 속간교잡종인 Festulolium braunii (품종, Paulita)의 국내 보급가능성을 타진하고자 3처리의 혼파유형 (1) Festulolium braunii (FB, 파종비율 50%)+orchardgrass(OG, 50%), (2) Festulolium braunii (FB, 80%)+red clover (RC, 20%) 및 (3) Festulolium braunii (FB, 20%)+orchardgrass(OG, 50%)+tall fescue(TF, 20%)+white clover(WC, 10%)을 두어 난괴법 4반복으로 건물수량과 품질을 비교하였으며 얻어진 결과는 다음과 같다. 건물수량은 처리간에 유의적인 차이는 없었으나 FB+RC 초지가 다른 혼파유형에 비하여 약간 많았다. CP 함량은 FB+RC 초지가 다른 혼파유형에 비하여 높았으며(P<0.05), 반대로 NDF와 ADF 함량은 다른 혼파유형에 비하여 오히려 낮은 결과를 가져왔다(P<0.05). CP와 DDM 수량은 FB+RC 초지가 다른 혼파유형에 비하여 높은 결과를 나타내었다(P<0.05). 97년의 마지막 예취시기에 조사한 식생비율은 모든 혼파유형에서 FB의 식생비율이 51~58%로 높게 유지되었다. 이상의 결과를 종합할 때 FB는 다른 초종과 혼파가능성은 충분하다고 하겠으며, 그 중 RC와 혼파하는 것이 가장 좋은 결과를 얻었다.

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척수손상 백서에서 서방형 성장호르몬의 투여가 신경회복에 미치는 영향 (The Effects of Sustained Release Growth Hormone in the Repair of Neurological Deficits in Rats with the Spinal Cord Injury)

  • 김민수;허정;권용석;이근철;김석권
    • Archives of Plastic Surgery
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    • 제35권3호
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    • pp.235-242
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    • 2008
  • Purpose: Due to increasing interest in the treatment of spinal cord injuries, many histopathological studies have been conducted to prove that many neurotrophic factors including growth hormone are important for regeneration of the injured spinal cord. Growth hormone has to be given everyday, however, and this negatively affects compliance in clinical trials. Recently, the invention of sustained release growth hormone (SRGH) that can be given just once a week may both help the regeneration of injured spinal cord and, at the same time, be more compliant and convenient for clinical patients. Methods: In this study, thirty 7-week-old female Spraque-Dawley rats were subjected to a weight-driven impact spinal cord injury. They were divided into 3 groups and Group I and II were injected with SRGH once a week for 4 weeks; Group I were injected into the injured spinal cord area, while Group II were injected into the peritoneal cavity. Meanwhile, Group III were injected with normal saline solution. The functional outcome was evaluated using the Basso-Beattie-Bresnahan motor rating score and the inclined plane test was done 4 weeks after the first injection. Histopathological examination was performed at the same time and the amount of residual white matter was measured in all groups. Results: After 4 weeks, Groups I and II showed greater improvement than Group III(the control group) in the functional test. In the control group, invasion of atypical phagocytes, axonal degeneration, edema and cavity formation in the posterior site of spinal cord gray matter was observed in histopatholgical examination. The rate of residual white matter in Group III was less than in the other groups. Conclusion: Data showed significant functional and histopathological improvement in the groups treated with SRGH into the spinal and peritoneal cavity compared with the control group. SRGH is therefore beneficial because it helps with regeneration of the injured spinal cord and improves the compliance and convenience of patients.

Clinical Implications of Focal Mineral Deposition in the Globus Pallidus on CT and Quantitative Susceptibility Mapping of MRI

  • Hyojin Kim;Jinhee Jang;Junghwa Kang;Seungun Jang;Yoonho Nam;Yangsean Choi;Na-young Shin;Kook-Jin Ahn;Bum-soo Kim
    • Korean Journal of Radiology
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    • 제23권7호
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    • pp.742-751
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    • 2022
  • Objective: To assess focal mineral deposition in the globus pallidus (GP) by CT and quantitative susceptibility mapping (QSM) of MRI scans and evaluate its clinical significance, particularly cerebrovascular degeneration. Materials and Methods: This study included 105 patients (66.1 ± 13.7 years; 40 male and 65 female) who underwent both CT and MRI with available QSM data between January 2017 and December 2019. The presence of focal mineral deposition in the GP on QSM (GPQSM) and CT (GPCT) was assessed visually using a three-point scale. Cerebrovascular risk factors and small vessel disease (SVD) imaging markers were also assessed. The clinical and radiological findings were compared between the different grades of GPQSM and GPCT. The relationship between GP grades and cerebrovascular risk factors and SVD imaging markers was assessed using univariable and multivariable linear regression analyses. Results: GPCT and GPQSM were significantly associated (p < 0.001) but were not identical. Higher GPCT and GPQSM grades showed smaller gray matter (p = 0.030 and p = 0.025, respectively) and white matter (p = 0.013 and p = 0.019, respectively) volumes, as well as larger GP volumes (p < 0.001 for both). Among SVD markers, white matter hyperintensity was significantly associated with GPCT (p = 0.006) and brain atrophy was significantly associated with GPQSM (p = 0.032) in at univariable analysis. In multivariable analysis, the normalized volume of the GP was independently positively associated with GPCT (p < 0.001) and GPQSM (p = 0.002), while the normalized volume of the GM was independently negatively associated with GPCT (p = 0.040) and GPQSM (p = 0.035). Conclusion: Focal mineral deposition in the GP on CT and QSM might be a potential imaging marker of cerebral vascular degeneration. Both were associated with increased GP volume.

Comparison of the growth performance, nutrient digestibility, fecal microflora, blood profiles, and meat quality of broilers, Korean native chickens and white semi broilers under an identical breeding environment

  • Oh, Han Jin;Kim, Kwon Jung;Bae, In Kyu;Yun, Won;Lee, Ji Hwan;Lee, Chang Hee;Kwak, Woo Gi;Liu, Shudong;An, Ji Seon;Yang, Seung Hun;Kim, Gok Mi;Choi, Yang il;Cho, Jin Ho
    • 농업과학연구
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    • 제46권2호
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    • pp.351-359
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    • 2019
  • The purpose of this study was to compare the growth performance, nutrient digestibility, fecal microflora, blood profiles and meat quality of broilers, Korean native chickens and white semi broilers under identical feeding conditions. Sixty 1-d chicks of each type were randomly placed into 12 pens per cage (5 chicks per cage) and fed commercial diets for 28, 49, and 28 days, respectively. The broilers showed a significantly higher (p < 0.05) growth performance from 0 to 4 weeks compared with the other types. Korean native chickens had a significantly higher (p < 0.05) digestibility of dry matter and nitrogen than that of the other species. The blood glucose was significantly higher in the Korean native chickens compared to the other species, and the blood cholesterol was significantly lower. The Lactobacillus content in Korean native chickens was significantly higher (p < 0.05) compared to the other species, and the E. coli content in the broilers was significantly higher (p < 0.05) than in the Korean native chickens and white semi broilers. In terms of meat quality, the breast meat of the broilers had a high water content and pH level. The breast meat of the white semi broilers had a significantly lower (p < 0.05) shear force than that of the other species. In conclusion, there was an interspecific physiological difference due to the age and body weight of the chickens. The broilers had a higher growth performance and meat quality compared to the Korean native chickens and white semi broilers.

대학생의 색동에 대한 인식과 이미지 분석 (An Analysis of Recognition and Image of Saek-dong in College Students)

  • 김여원;최종명
    • 복식
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    • 제57권7호
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    • pp.108-121
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    • 2007
  • The purpose of this study was to seek the means of enlarging the application of Saek-dong to fashion products by surveying and analysing the recognition and image of Saek-dong in college students. As a research procedure, the bibliographical survey on the meaning and history of Saek-dong was preceded in this study, and the students were examined on the recognition and image of Saek-dong through the questionnaires. The female students were more acquiesced with the Saek-dong and Saek-dong clothing than the male students. And the students thought that the Saek-dong was our original and traditional clothing because it was worn by our ancestors from the earliest years. The word Saek-dong reminded them of red, yellow, blue, green, white and red-brown colors in order of appearance. The most familiar color-arrange to them was red+yellow+dark-brown+green+blue, and the blue, purple, green, red, white color was thought as manly Saek-dong colors and the yellow, red, dark-brown, pink, white was regarded as feminine Saek-dong colors. Saek-dong was primarily associated with the image of Saek-dong clothing and most of the students expressed their feeling about the Saek-dong as 'cute.' Most of the students responded that the practical Hanbok was best illustrated as the most applied clothing of Saek-dong and that the attempt to apply the color and pattern of Saek-dong to other modern artistic products was likely to damage the worth of traditional Saek-dong. When it comes to the matter of applying the design of Saek-dong to the fashion products, male students thought that it could be best applied to the shirts, while female students thought that the design of Saek-dong could best be applied to the personal ornaments.

'육체의 복수' -포크너의 『압살롬, 압살롬!』에 나타난 성적, 인종적 타자의 귀환 (Revenge of the Flesh: The Return of Sexual and Racial Otherness in Faulkner's Absalom, Absalom!)

  • 권지은
    • 영어영문학
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    • 제58권4호
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    • pp.701-721
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    • 2012
  • This paper aims to revisit William Faulkner's Absalom, Absalom! by focusing on the corporeal body and its role in dismantling the Southern ideology of white patriarchy. The latter, which is represented by Thomas Sutpen and his attempt to establish a white male dynasty, is a symbolic space in which the corporeal body turns into a symbolic one through the process of inscribing social ideologies on it. However, this symbolic space is also a contending site between the two bodies. The symbolic body of Sutpen cannot entirely erase its corporeal traces, and therefore the corporeal body, which is buried but nonetheless existent, threatens to undermine rules and premises of the symbolic order. Given that, this paper approaches Faulkner's critique of the Southern white patriarchal ideology from the tension that the corporeal body and the symbolic body create. The 'flesh' roughly corresponds to racial and sexual otherness, namely black flesh and the homoerotic desire of male body. Although they-as the matter of race and that of gender - function in different levels of signification, they still share a common purpose in revealing the logical paradox within Sutpen's symbolic order. The idea of pure whiteness that Sutpen subscribes to is a concept that prerequisites the existence of blackness. Likewise, his idea of male homosociality based upon patriarchal legacy stands precariously on the verge of disintegrating into homoetoricism. As internal otherness that Sutpen's symbolic order cannot fully incorporate, the corporeal body functions to indicate the limitation of Sutpen's Design and its body-signification process.

EFFECT OF LEVEL OF FEED INTAKE ON THE EXCRETION OF PURINE DERIVATIVES AND PURINE DERIVATIVES TO CREATININE RATIO IN THE URINE OF SHEEP

  • Han, Y.K.;Shin, H.T.;Landis, J.
    • Asian-Australasian Journal of Animal Sciences
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    • 제5권3호
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    • pp.465-468
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    • 1992
  • Urinary purine derivatives and creatinine excretion was measured in a total of 4 white Alpine sheep. They were given diets 718 to 1060 g/kg dry matter (DM) of roughage. The crude protein content of this diets was on average $93.87{\pm}5.57g$ in kg DM. Purine derivatives-N excretion increased linearly with incremental DM intake and was significantly correlated (n = 16) with amounts of digestible organic matter (DOM) intake: allantoin-N (mg) = 1.205 (${\pm}0.070$) $\times$ DOM (g) - 136.709 (${\pm}37.399$), r = 0.9770, RSD = 22.97; uricacid-N (mg) = 0.131 (${\pm}0.041$) $\times$ DOM (g) + 11.380 (${\pm}21.881$), r = 0.6306, RSD = 13.44; Hypoxanthine-N (mg) = 0.049 (${\pm}0.014$) $\times$ DOM (g) - 28.640 (${\pm}7.708$), r = 0.6544, RSD = 4.73; total purine derivatives-N (mg) = 1.385 (${\pm}0.083$) $\times$ DOM (g) - 90.261 (${\pm}44.552$), r = 0.9706, RSD = 27.47. Microbial protein synthesis per kg DOM was estimated of 113 g. The urinary creatinine-N excretion was on average 9.10 mg/kg live weight (LW) with a standard error of 0.12 mg creatinine-N per kg LW. The excretion of creatinine excreton was not related to feed intake. Daily creatinine excretion (mg/d) was calculated from individual LW measurements and the average creatinine excretion (mg/kg LW). It was possible to predict the daily urinary purine derivatives excretion (r = 0.9720 for allantoin, r = 0.9886 for total purine derivatives) from the ratio of purine derivatives (mg/100 ml) and creatinine (mg/100 ml) in the urine and the daily creatinine excretion.

흰쥐의 척수에서 아연이 함유된 신경원에 대한 조직화학 및 전자현미경적 연구 (Histochemical and Electron Microscopic Study on the Zinc-containing Neurons in Rat Spinal Cord)

  • 조현욱;한원동
    • Applied Microscopy
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    • 제26권2호
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    • pp.243-252
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    • 1996
  • Sodium selenite를 피하주사하고 은 증폭시켜 흰쥐 척수에 있는 아연이 함유된 신경원의 포체와 bouton을 표지하였다. 표지된 신경원 세포체는 회백질의 V, VI, VII 및 X층에 분포하였다. 8시간 생존시킨 경우 아연 셀레늄 반응물이 역행수송되어 세포체에 침전되었다. 이것은 척수에 있는 아연이 함유된 신경원의 전부 혹은 일부가 개재신경원인 것으로 생각된다. 1시간 생존시킨 경우 아연 침전물로 표지된 축삭 bouton들이 회백질과 백질의 척수전삭 및 복측삭에 있는 돌기에 분포하였다. 특히 AMG로 염색된 큰 형태의 bouton 이 IX층에 나타났다. 미세구조적으로 아연 침전물은 생존시간에 따라서 아연이 함유된 신경원의 세포질 리소좀이나 bouton 내의 vesicle에 위치하였다.

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고 자장에서 Dynamic Susceptibility Contrast 효과에 관한 연구 : Gradient EPI와 Spin-EPI기법의 비교 (A Study on Dynamic Susceptibility-weighted Perfusion MR Imaging at High Magnetic Filed : Comparison of Gradient Echo-EPI and Spin Echo-EPI)

  • 구은회;채홍인;박종배;임청환;김정구
    • 대한디지털의료영상학회논문지
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    • 제9권2호
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    • pp.11-16
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    • 2007
  • We have evaluated and compared of gradient echo and spin echo EPI for compensating about deeply distortion aspect in case of post-operation patients in magnetic resonance image. A total of 100 patients were performed on 3.0 T(GE Signa Excite E2, USA) with 8ch head coil. As a result of analysis, The SNRs of whiter and gray matter areas were 36.74 $\pm$ 06 and 39.96 $\pm$ 09 in the gradient echo EPI, the SNRs which white and gray matter areas were slightly higher than gradient echo EPI(P<0.005, paired student t-test). It was 46.24 $\pm$ 11 and 51.38 $\pm$ 13 in gradient and spin echo EPI, respectively. The signal intensity in the whiter and gray matter areas also were 87.33 $\pm$ 15.24 and 140.66 $\pm$ 13.45 in the gradient echo EPI techniques, The signal intensity of gradient echo EPI showed higher values compared to spin echo EPI. Otherwise, gradient echo EPI technique is distortion enough to operation wound and edge of the image, while spin echo EPI technique did not appear almost. In this point, the spin echo EPI technique, after surgical operation according to patient state beside gradient echo EPI techniques that signalbeside gradient echo EPI techniques that signal intensity is high and patient's case which image distortion is serious by metal etc, will be provide the useful information in adults and pediatric patients.

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