• Environmental Analysis Health and Toxicology
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• v.24 no.1
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• pp.25-32
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• 2009

Toxicity of ocean dumping wastes(dye waste, urban sewage, food waste) were examined by observing fertilization and embryo development rates of the Sea Urchin, Strongylocentrotus nudus. Spawning was induced by injecting 1 mL of 0.5 M KCl into coelomic cavity. Males released white or cream-colored sperms and females released yellow or orange-colored eggs. Experiments were began within 30 min after the collection of both gametes. The fertilization and embryo development rates tests were performed for 10 min and 48 h after fertilization, respectively. The fertilization and embryo development rates in the control condition(not including ocean dumping wastes sludge elutriate) were greater than 90%, but markedly decreased with increasing concentrations of ocean dumping waste sludge elutriate. The fertilization and normal embryogenesis rates were significantly inhibited in all waste sludge elutriate from dye waste($EC_{50}$=5.76; $EC_{50}$=4.53), urban sewage($EC_{50}$=9.82; $EC_{50}$=9.67) and food waste($EC_{50}$=3.90; $EC_{50}$=3.27), respectively. The NOEC(>3.13%) and LOEC(3.13%) of fertiliztion and normal embryogenesis rates very similar in all waste sludge elutriate. These results suggest biological assay using the fertilization and embryo development rates of S. nudus are very useful test method for the ecological toxicity assessment of ocean dumping wastes.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.55 no.5
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• pp.505-513
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• 2022

In this study, 143 strains of Enterococcus spp. were isolated from inland pollution sources near shellfish farms on the west coast of South Korea. Not all isolated Enterococcus spp. strains possessed vancomycin resistance genes (VanA and VanB). However, since vancomycin-resistance Enterococcus (VRE) have been detected not only in the clinical field but also out in the world, it is possible that the VRE gene may be transferred to other bacterial strains commonly found in coastal waters where seafood is produced. It is important to monitor trends in the appearance of VRE. In addition, antimicrobial resistance patterns of isolates were examined in this study. Overall antimicrobial resistance rates were high: ciprofloxacin (32.2% of isolates resistant), chloramphenicol (30.8%), quinupristin/dalfopristin (19.6%), and tylosin (15.4%). Eight E. faecium strains (6.2%), out of the 129 strains assessed, showed multidrug resistance. All multidrug-resistant E. faecium showed resistance to erythromycin, quinupristin/dalfopristin, tetracycline, and tylosin, in all 14 strains. All multidrug-resistant E. faecalis showed resistance to erythromycin, quinupristin/dalfopristin, tetracycline, and tylosin. Both multidrug-resistant E. faecium and multidrug-resistant E. faecalis showed common resistance to erythromycin, quinupristin/dalfopristin, tetracycline, and tylosin.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.55 no.5
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• pp.495-504
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• 2022

This study examined the antimicrobials properties of bacteria using the minimum inhibitory concentration method. The bacteria were isolated from 30 shellfish (oysters and short neck clams) collected from Jawol-myeon, Ongjin-gun, Incheon and Iwon-myeon, Taean-gun, Chungcheongnam-do, on the west coast of Korea. A total of 528 bacteria were isolated from June to October 2020 and were classified into land-originating (LB; 264 strains) and marine-originating (MB; 264 strains) bacterial groups. Of the LB strains, 10 genera were identified, of which nine were Enterobacteriaceae. All MB strains were identified as species of the genus Vibrio spp.. Antimicrobial resistance to one or more agents was observed in 77.3% of the LB strains, and 90-100% of them were resistant to ampicillin Escherichia spp. were not resistant to ampicillin. The overall multidrug resistance rate of the LB strains was 49.2%, with 85 resistance patterns. Antimicrobial resistance to one or more agents was observed in 98.1% of the MB strains, because most of the V. alginolyticus and V. parahaemolyticus strains were resistant to ampicillin. The overall multidrug resistance rate of the MB strains was 1.9% with 19 resistance patterns.

• The Journal of Internal Korean Medicine
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• v.43 no.3
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• pp.477-484
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• 2022

Objective: The purpose of this study was to report the improvement effect of symptoms of integrative cancer treatment (ICT) on recurrent gallbladder cancer patients. Methods: A 73-year-old patient with recurrent gallbladder cancer visited the Daejeon Korean Medicine Hospital of Daejeon University East West Cancer Center (EWCC) on February 2022. After the diagnosis of gallbladder cancer, the patient underwent cholecystectomy and relapsed during follow-up. After the operation, the cancer recurred during follow-up, and after radiation treatment, she had been receiving ICT since February 2022. The clinical outcomes were measured by X-ray, computed tomography (CT), laboratory findings, including tumor markers (CEA, CA19-9), and numeric rating scales (NRS). Results: After treatment, abdominal pain was relieved from NRS 5 to 2, and abdominal circumference decreased from 74.5 to 67. During and after treatment, we found neither hepatotoxicity nor nephrotoxicity in the laboratory findings. Conclusion: This case study suggests that ICT may improve symptoms in patients with gallbladder cancer.

• The Journal of Internal Korean Medicine
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• v.45 no.3
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• pp.508-518
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• 2024

Objectives: To report a correlation of IL-6 of pancreatic cancer and cancer progression in three pancreatic cancer patients. Method: Three pancreatic cancer patients were monitored for changes in IL-6 levels, tumor markers (CEA, CA19-9), and clinical outcomes over their treatment period. Results: Patient 1's IL-6 levels rose with liver metastasis and tumor progression, coinciding with increases in tumor markers. Patient 2's IL-6 levels remained elevated during chemotherapy, correlating with tumor growth. Patient 3's IL-6 levels spiked prior to cancer progression. Conclusion: Elevated IL-6 levels were observed in advancing pancreatic cancer patients, suggesting IL-6 as a potential biomarker for monitoring cancer progression in pancreatic cancer. Regular IL-6 monitoring could improve prognostic evaluations and treatment strategies.

• Journal of the korean society of oceanography
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• v.34 no.3
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• pp.144-150
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• 1999

Slope sedimentation on the modern west Florida continental margin is controlled by pelagic carbonate accumulation and off-shelf sedimentation of neritic carbonates and terrigenous fines. Production and deposition of pelagic carbonates by planktonic foraminifera and coccoliths have played a significant role in the total slope sedimentation and are mainly promoted by sea-surface productivity. Organic carbon data reflect the relatively high biological productivity in surface waters, indicating high accumulation of biogenic calcareous sediments. The surface-water productivity in the study area is supported by the relation among microfossil assemblages, carbonate mineralogy and sedimentary organic carbon.

• The Journal of the Society of Stroke on Korean Medicine
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• v.11 no.1
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• pp.18-25
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• 2010

Object : This study was conducted as part of the national project to standardize stroke diagnosis in Korean medicine. In this study, we aimed to evaluate the characteristics of acute stroke between heat pattern group and cold pattern group. Methods : We recruited stroke patients from 5 universities(Kyung-Hee University oriental medical center, Kyung-Hee University East-West Neo medical center, Kyungwon university lncheon oriental medical center, Kyungwon university Songpa oriental medical center and DongGuk university llsan oriental medical center) from April, 2007 until February, 2010. We diagnosed them and selected 463 heat pattern patients and 182 cold pattern patients. Results : We find that the risk factor of smoking, alcohol, diet(prefer to meat) are more associated with the heat pattern group. On the other hand, inflammation history in recent 3 months and diet(prefer to sea food) are more associated with the cold pattern group. RBC, Hg, Hct, TG, CK and Cl are more related to the heat pattern group. CPT, total cholesterol and HDL are more related to the cold pattern group. Tae-eum type takes high distribution of the heat pattern group, and So-eum type takes high distribution of the cold pattern group. Conclusions : This study provides evidence that the heat pattern group have more risk factor than the cold pattern group.

• Journal of Species Research
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• v.6 no.2
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• pp.181-189
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• 2017

Sixteen species of macrochelid mites were collected on the surface of scarab dung beetles in Mount Gede-Pangrango National Park, West Java, Indonesia. Of these, one species, Macrocheles gedeensis sp. nov. is described here as new to science. The other fifteen species were Holostaspella katakurai Hartini and Takaku, 2003, H. oblonga Hartini and Takaku, 2010, H. villosa Hartini and Takaku, 2010, Neopodocinum halimunense Hartini and Takaku, 2003, N. subjaspersi Hartini and Takaku, 2003, Neopodocinum sp., Macrocheles dispar (Berlese, 1910), M. entetiensis Hartini and Takaku, 2005, M. hallidayi Walter and Krantz, 1986, M. jabarensis Hartini and Takaku, 2003, M. kraepelini (Berlese, 1905), M. pumilus Hartini, Dwibadra and Takaku, 2009, M. turgoensis Hartini, Dwibadra and Takaku, 2009, M. sukabumiensis Hartini and Takaku, 2003, and M. sukaramiensis Takaku, 2001.

• Journal of Biomedical Engineering Research
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• v.27 no.6
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• pp.409-417
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• 2006

Research on neural circuit is a difficult area due to complexity and inaccessibility. Due to recent developments, the research using multi-electrode array of cells or tissues has become an important research area. However, there are some difficulties to decode the submerged meaning from huge and complex neural data. Moreover, it needs a harmonic collaboration between informatics and bioscience. In this paper, we have developed a custom-designed signal processing technique for multi-electrode array measured neural responses induced by electrical stimuli to the hippocampal tissue slices of the rat brain. The raw data from hippocampal slice using the multi-electrode array system were saved in a computer. Then we estimated characteristic points in each channel and calculated the total activity. To estimate the points, we used the Polynomial Fitting Approximation Method. Using the calculated total activity, we could provide the histogram or pseudo-image matrix to help interpretation of results.

• Journal of Astronomy and Space Sciences
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• v.29 no.3
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• pp.269-274
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• 2012

Kinematic global positioning system precise point positioning (GPS PPP) technology is widely used to the several area such as monitoring of crustal movement and precise orbit determination (POD) using the dual-frequency GPS observations. In this study we developed a kinematic PPP technology and applied 3-pass (forward/backward/forward) filter for the stabilization of the initial state of the parameters to be estimated. For verification of results, we obtained GPS data sets from six international GPS reference stations (ALGO, AMC2, BJFS, GRAZ, IENG and TSKB) and processed in daily basis by using the developed software. As a result, the mean position errors by kinematic PPP showed 0.51 cm in the east-west direction, 0.31 cm in the north-south direction and 1.02 cm in the up-down direction. The root mean square values produced from them were 1.59 cm for the east-west component, 1.26 cm for the south-west component and 2.95 cm for the up-down component.