• Title/Summary/Keyword: Well differentiated

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Surgical Treatment of Well-Differentiated Fetal Adenocarcinoma - A case report - (태아성 선암종의 외과적 치료 1례보고)

  • Song, Dong-Seop;Chung, Won-Sang;Kim, Hyuck;Kim, Young-Hak;Kang, Jung-Ho;Lee, Chul-Bum;Jeon, Seok-Chol;Lee, Won-Mi;Hong, Eun-Kyung
    • Journal of Chest Surgery
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    • v.34 no.7
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    • pp.566-568
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    • 2001
  • WDFA(Well-differentiated fetal adenocarcinoma) histologically resembles pulmonary blastoma. It is also thought to be a subtype of pulmonary blastoma, which has differentiated epithelial features resembling the fetal lung among its epithelial features and sarcomatous features. We recently encounted a patient who underwent surgery for WDFA. A 19-year-old man had a mass shadow in the upper lobe of the left lung. The tumor was diagnosed as pulmonary blastoma as a result of fine needle aspiration biopsy, and left upper lobe lobectomy was performed. No sarcomatous features was observed on postoperative histologic assessment, and the patient was diagnosed as having WDFA. This case is reported with a discussion of the literatures.

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A Hierarchical Deficit Round-Robin Packet Scheduling Algorithm for User-Oriented Relative Differentiated Services (사용자 기반 상대적 차별화를 위한 계층적 결손 보완 라운드-로빈 스케줄링 알고리즘)

  • Pyun Kihyun;Lee Jong-Yeol;Cho Sung-Ik
    • Journal of KIISE:Information Networking
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    • v.32 no.6
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    • pp.676-686
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    • 2005
  • The Internet users as well as network providers are eager to have different qualities of service among users beyond the best-effort. In this paper, we propose a scheduling algorithm that provides a differentiated service in the granularity of user sessions. The proposed algorithm is a Hierarchical Deficit Round-Robin (H-DRR) algorithm that is an extension of an existing DRR algorithm. A main advantage is that H-DRR provides service differentiation for throughput-intensive applications such as FTP as well as delay-sensitive applications such as telnet or VoIP without distinguishing the types of applications. The most importance in providing a service differentiation in term of network providers is to have controllability and predictability. We show that H-DRR is superior to DRR in terms of controllability and predictability through both mathematical analysis and simulation experiments. Nevertheless, H-DRR requires O(1) complexity for implementation.

Provisioning of QoS Adaptability in Wired-Wireless Integrated Networks

  • Guo, Mian;Jiang, Shengming;Guan, Quansheng;Mao, Huachao
    • Journal of Communications and Networks
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    • v.15 no.1
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    • pp.61-70
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    • 2013
  • The increasing number of mobile users and the popularity of real-time applications make wired-wireless integrated network extremely attractive. In this case, quality of service (QoS) adaptability is particularly important since some important features of the integrated network call for QoS adaptability, such as mobility, bursty applications and so on. Traditional QoS schemes include integrated service (IntServ) and differentiated service (DiffSev) as well as their variants. However, they are not able to balance well between scalability and QoS granularity. For example, IntServ faces the scalability problem, while DiffServ can only provide coarse granular QoS. In addition, they are also unable to efficiently support QoS adaptability. Therefore, a per-packet differentiated queueing service (DQS) was proposed. DQS was originally proposed to balance between scalability and QoS granularity in wired networks and then extended to wireless networks. This paper mainly discusses how to use DQS to support QoS adaptability in wired-wireless integrated networks. To this end, we propose a scheme to determine dynamic delay bounds, which is the key step to implement DQS to support QoS adaptability. Simulation studies along with some discussions are further conducted to investigate the QoS adaptability of the proposed scheme, especially in terms of its support of QoS adaptability to mobility and to bursty real-time applications.

A Case of Atypical Lipomatous Tumor of the Neck (경부에 발생한 비전형 지방종 1예)

  • Heo, Geon;Yoo, Young-Sam;Kim, Sang-Woo;Kwon, Ji-Eun
    • Korean Journal of Head & Neck Oncology
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    • v.26 no.2
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    • pp.256-258
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    • 2010
  • Although liposarcoma is the second most common soft tissue sarcoma in adults, the incidence of liposarcoma in the head and neck is low. The histologic nature of liposarcoma is correlated clinically with treatment outcome, but histologic classification of liposarcoma is controversial. Well-differentiated liposarcoma and atypical lipoma are pathologic synonyms because they are identical lesions both morphologically and karyotypically. They represent the lowest grade lesions in the spectrum of liposarcoma. The terms "atypical lipoma" were introduced specifically to describe well-differentiated liposarcomas occurring in the extremities, because of their better prognosis in comparison with their retroperitoneal counterparts. We present 1 case of atypical lipomatous tumor of the neck.

A Case of Pulmonary Blastoma (폐아세포종 1예)

  • Park, Kang-Soo;Hahm, Hee-Yong;Hwang, Seong-Bo;Choi, Soo-Jeon;Lee, Shin-Yeong;Ko, Ill-Hyang
    • Tuberculosis and Respiratory Diseases
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    • v.41 no.4
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    • pp.418-423
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    • 1994
  • Pulmonary blastoma is a rare lung tumor resembling fetal lung tissue. Pathologically the tumor can be classified to 2 groups, well-differentiated fetal adenocarcinoma(WDFA) and biphasic blastoma. WDFA has more favorable progonosis with fewer metastasis at initial presentation and fewer recurrence after treatment. We experienced a case of pulmonary blastoma in 32-year-old female patient. The patient was refered to our hospital because of abnormal mass shadow in right middle lobe. The diagnosis of pulmonary blastoma(WDFA type, Stage I T2N0M0) was confirmed after right middle lobectomy. We followed up 22 months without an evidence of recurrence.

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Systematic Studies on the Freshwater Goby, Rhinogobius Species (Perciformes, Geobiidae) III. Geographic Variation and Subspecific Differentiation in Rhinogobius giurinus, with a Comment on Genetic Relationships among Four Species of the Genus Rhinogobius in Korea

  • Kim, Jong-Bum;Kim, Jae-Heup;Yang, Suh-Yung
    • Animal cells and systems
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    • v.1 no.4
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    • pp.529-534
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    • 1997
  • Genetic and morphological variations of Rhinogobius giurinus were surveyed. Populations of R.giurinus were clearly divided into two forms (Form-A and Form-B). Starch gel variation of this species. Three loci (Aco, Mpi, aGpd) out of 27 showed fixed allelic differences between Form-A and Form-B and they are well differentiated from each other genetically (Rogers' S=0.871). These two forms, moreover, are found to be allopatric in distribution and morphologi cally different in body length and caudal fin color pattern. Therefore, they are considered as two distinct taxa of subspecific rank. In addition, the genetic relationships among 5 taxa within 4 species of the genus Rhinogobius were investigated. Three species of the Rhinogobius brunneus complex (R.sp. OR, R. sp. CB and R. sp. CO) are well differentiated from each other genetically and two taxa of R. giurinus are genetically divergent from three species of the Rhinosotius brunneus complex (average Nei's D=0.603, average Rogers'=0.534).

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Well-Differentiated Squamous Cell Carcinoma Found on the Tail of a Captive Leopard (Panthera Pardus): The Importance of Diagnostic Tests

  • Kim, Sungryong;Hong, Sunghyun S.;Kim, Jeong-Ho;Na, Ki-Jeong
    • Journal of Veterinary Clinics
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    • v.39 no.2
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    • pp.70-74
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    • 2022
  • A 14-year-old intact male captive leopard (Panthera pardus) first presented with a focal alopecic lesion on the dorsal aspect of the distal one-third of its tail. Although itraconazole was administered, the lesion progressed deeper and became ulcerated due to self-trauma. Due to the wild nature of the leopard, daily dressing of the wound and replacing the bandages without anesthesia became too dangerous, and amputation became necessary. A postoperative tissue sample was submitted for histopathological examination, and tramadol, amoxicillin/clavulanate, and gabapentin were administered. In the days following the amputation, the leopard's appetite significantly decreased, and the patient passed away 18 days later. Histopathological examination of the specimen revealed well-differentiated squamous cell carcinoma (SCC). In hindsight, had more cells been collected by a fine-needle aspirate (FNA) biopsy or had additional FNA biopsies been performed, SCC might have been diagnosed based on its cytological features rather than delayed histopathological findings. The current study highlights the critical reasons why clinicians may often misdiagnose SCC and the importance of being more aware of potential tumors in ulcerative lesions, which are often incorrectly treated as infectious skin diseases. This is also the first report of cutaneous SCC in a leopard.

Profiles of Epstein-Barr Virus Associated Gastric Carcinomas in Brunei Darussalam

  • Yen, Rachel Lai Siaw;Telisinghe, Pemasari Upali;Cunningham, Anne;Abdullah, Muhd Syafiq;Chong, Chee Fui;Chong, Vui Heng
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.23
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    • pp.10489-10493
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    • 2015
  • Background: Gastric cancer is the second most common gastrointestinal cancer and is largely attributed to Helicobacter pylori (H. pylori) infection. In addition, studies have also shown association with Epstein-Barr virus (EBV) in 10% of gastric cancers. This study assessed the characteristics of EBV associated gastric cancers (EBVaGC) in Brunei Darussalam. Materials and Methods: This study included gastric cancers diagnosed between 2008 and 2012, registered with the Department of Pathology RIPAS Hospital, Brunei Darussalam. Clinical case notes were systematically reviewed. Histology specimens were all stained for EBV and also assessed for intestinal metaplasia and H. pylori. Results: There were a total of 81 patients (54 male and 27 females) with a mean age of $65.8{\pm}14.8years$ included in the study. Intestinal metaplasia and active H. pylori infection were detected in 40.7% and 30.9% respectively. A majority of the tumors were proximally located (55.6%), most poorly differentiated (well differentiated 16%, moderately differentiated 30.9% and poorly differentiated 53.1%) and the stages at diagnosis were; stage I (44.4%), stage II (23.5%), stage III (8.6%) and stage IV (23.5%). EBV positivity (EBVaGC) was seen in 30.9%. Between EBVaGC and EBV negative gastric cancers, there were no significant differences (age, gender, ethnic group, presence of Intestinal metaplasia, tumor locations, stages of disease and degree of tumor differentiation). Conclusions: This study showed that a third of gastric cancers in Brunei Darussalam were positive for EBV, higher than what have been reported in the literature. However, there were no significant differences between EBVaGC and EBV negative gastric cancers. This suggests that the role of EBV in gastric cancer may be mostly incidental rather than any causal relation. However, further studies are required.

Development of a Guideline for the Application of a Diagnostic Tool for Menopausal Syndromes Based on the Use of Systemic Review and Delphi Method (체계적 문헌고찰과 델파이 기법을 활용한 갱년기장애 변증(辨證)진단 도구 개발을 위한 기초 연구)

  • Lee, In-Seon;Kim, Dong-Il;Yoo, Jeong-Eun;Kang, Chang-Wan
    • The Journal of Korean Obstetrics and Gynecology
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    • v.30 no.4
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    • pp.175-202
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    • 2017
  • Objectives: This study was conducted towards developing a screening tool for syndrome differentiation in the diagnosis of menopause in menopausal and perimenopausal women. Methods: We conducted a literature review of studies on menopausal diagnosis based on syndrome differentiation, and examined well-founded differentiated syndromes and their respective clinical symptoms. Based on the findings, we created a questionnaire through consultations with Oriental medicine experts in physiology, pathology, and diagnostics. Finally, the research team conducted an expert Delphi study on differentiated syndromes and the associated clinical symptoms. Results: Seven differentiated syndromes were selected, including Liver Depression (肝鬱), Kidney Yin Deficiency (腎陰虛), Kidney Yang Deficiency (腎陽虛), Liver and Kidney Yin Deficiency (肝腎陰虛), Kidney Yin and Yang Deficiency (腎陰陽兩虛), Heart-Kidney Noninteraction (心腎不交), and Dual Deficiency of Heart and Spleen (心脾兩虛); 4 disease locations, including liver (肝), heart (心), spleen (脾), and kidney (腎); and 3 disease natures, including Yin Deficiency (陰虛), Qi Stagnation (氣滯), and Blood Deficiency (血虛). In addition, we added 3 supplemental disease natures, including Yang Deficiency (陽虛), Qi Deficiency (氣虛), and Heat (火熱), in consideration of syndrome differentiation categories that may possibly be added in a follow-up clinical questionnaire. Conclusions: This resulted in a total of 7 differentiated syndromes, 4 disease locations, and 6 disease natures. We translated the clinical symptoms of these 17 categories into Korean Hangeul. After consulting with 5 Oriental medicine experts and a psychology expert, we produced a questionnaire for use in diagnosing menopause based on syndrome differentiation. The calculation of scores for the syndrome differentiation screening tool will be confirmed through clinical research based on the results of a review of existing literature.