• Journal of Ginseng Research
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• v.20 no.1
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• pp.49-53
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• 1996

The purpose of this study was to analyze the electrophoretic patterns of soluble proteins from ginseng roots and to compare the protein patterns from Korean ginseng and American quinquefolium. The size difference was found in the major protein bands of a molecular weight of about 27,000 between Korean ginseng and American quinquefolium. The protein band of a molecular weight of 22,000 showed a quantitative difference in its amount. The major 27 K proteins appeared to form a complex heterodimer of 66,000 and to have internal bisulfide bonds, from band shifting studies under non-denaturing conditions. Three peaks appeared when the protein extract from root homogenates was purified using gel filtration and DEAE ion exchange chromatography. The examination of physiological activity and further purification of these fractions are underway.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.18 no.5
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• pp.1260-1272
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• 2024

This paper tackles the prevalent challenges faced by existing tourism route recommendation methods, including data sparsity, cold start, and low accuracy. To address these issues, a novel intelligent tourism route recommendation method based on collaborative filtering is introduced. The proposed method incorporates a series of key steps. Firstly, it calculates the interest level of users by analyzing the item attribute rating values. By leveraging this information, the method can effectively capture the preferences and interests of users. Additionally, a user attribute rating matrix is constructed by extracting implicit user behavior preferences, providing a comprehensive understanding of user preferences. Recognizing that user interests can evolve over time, a weight function is introduced to account for the possibility of interest shifting during product use. This weight function enhances the accuracy of recommendations by adapting to the changing preferences of users, improving the overall quality of the suggested tourism routes. The results demonstrate the significant advantages of the approach. Specifically, the proposed method successfully alleviates the problem of data sparsity, enhances neighbor selection, and generates tourism route recommendations that exhibit higher accuracy compared to existing methods.

• Journal of Microbiology and Biotechnology
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• v.16 no.12
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• pp.1849-1855
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• 2006

It has been shown that the initial conditions of bacterial cultivation are extremely important for the successful production of hyaluronic acid (HA) by fermentation. We investigated several parameters that affect cell growth rate and the productivity and molecular weight of hyaluronic acid--i.e., agitation speed, aeration rate, culture temperature, pH, and pressure--to determine how to optimize the production of HA by Streptococcus zooepidemicus on an industrial scale. Using a 30-1 jar fermentor under laboratory conditions, we achieved maximum HA productivity and biomass when the agitation speed and aeration rate were increased simultaneously. By shifting the temperature downward from 35$^{\circ}C$ to 32$^{\circ}C$ at key levels of cell growth during the fermentation process, we were able to obtain HA with a molecular weight of $2.8{\times}10^6$ at a productivity of 5.3 g/l. Moreover, we reproduced these optimized conditions successfully in three 30-1 jar fermentors. By reproducing these conditions in a 3-$m^3$ fermentor, we were able to produce HA with a molecular weight of $2.9{\times}10^6$ at a productivity of 5.4 g/l under large-scale conditions.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.18 no.2
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• pp.67-75
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• 2012

Background: Hemiplegic patients have the problems of the balance and weight shifting to the affected leg in walking. The aim of this study was to investigate the effect of unilateral stepping exercise combined with auditory feedback on balance and walking ability of the hemiplegic patients. Methods: Thirty hemiplegic patients were allocated in study group (n=15) or control group (n=15). General exercise and weight supporting exercise were conducted for the control group, and general exercises and unilateral stepping exercise combined with auditory feedback were conducted for the study group. Exercise were conducted three times a week for six weeks. Balance ability was measured by Berg Balance Scale (BBS), postural assessment scale for stroke (PASS), and performance-oriented mobility assessment (POMA). Walking ability was measured by time up and go test (TUG), 10m walk test (10mWT), and six minutes walk test (6MWT). Results: Balance and walking ability were significant increased in both group (p<.05). Balance and walking ability of the study group were more increased than that of the control group (p<.05). Conclusions: Unilateral stepping exercise combined with auditory feedback is more effective than weight supporting exercise to increase on balance and walking ability for the hemiplegic patients.

• Journal of Korean Society of Water and Wastewater
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• v.19 no.4
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• pp.480-486
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• 2005

The main goals of this work are to investigate the effect of molecular weight distribution(MWD) and activated carbon adsorption capacity after conventional coagulation and enhanced coagulation. The ozonation was very effective to decompose the NOM to smaller size and to remove molecular smaller than 1,000. The concentration of DOC was reduced 0.25mg/L and 0.56mg/L by the conventional coagulation and the enhanced coagulation, respectively The conventional coagulation was not effective to remove NOM. However, the enhanced coagulation was effective to remove MW bigger than 10,000. The higher MW was shifted to smaller weight by ozonation in the raw water and the after conventional coagulation. After enhanced coagulation the MW had not changed significantly by ozonation. Also, it was observed that the ozone dosage did not have significant impact on MW shifting to smaller size. The adsorption capacity simulated by IAST comparing K values showed that the adsorption capacity was not impacted by ozone doses. There was very strong correlation between MW smaller than 10,000 and the mid- and strongly adsorbable fractions.

• Journal of Korean Physical Therapy Science
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• v.11 no.4
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• pp.29-37
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• 2004

Measurements of plantar pressure provide an indication of foot and ankle function during gait and other functional activities because the foot and ankle provide necessary support and flexibility for weight bearing and weight shifting while people are performing these activities. Plantar pressure is being increasingly used in both research and clinical practice to measure the effects of various footwear and physical therapy intervention. The influence of walking speed and ground inclination on plantar pressure parameters However has not been evaluated in detail. So, in this study to determine the effect of changes in walking speed and ground inclination on plantar pressure treadmills with different walking speeds and inclination were used. Plantar pressure parameters were measured with the Parotec system using the walking and running in 20 healthy participants(10 male, 10 female) aged $20{\sim}28$(mean 22.22, S.D.2.26 years) when slow walking and running. The result of this study with increased die walking speed, the peak pressure of 1st, 5th metatarsal head and total contact time and impulse total at the forefoot was affected by walking speed; however, die peak pressure, contact time and impulse total at the forefoot was not affected by ground inclination.

• Korean Journal of Applied Biomechanics
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• v.20 no.2
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• pp.213-219
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• 2010

The purpose of this study is developing a method to analyze and evaluate a golf swing motion using the ground reaction force (GRF) data. Proper weight shifting is essential for a successful shot in golf swing and this could be evaluated by means of the forces between the feet and ground. GRF during the swing were measured from 15 low-handicapped male golfers including professionals. Four clubs(driver, iron 3, iron 5, and iron 7) were selected to analyze the differences due to different characteristics of club. Swings of each subject were taken using a high speed video camera and GRF data were taken simultaneously by two AMTI force platforms. To simplify the GRF data, forces of the three major component of GRF(vertical, lateral, anterior-posterior force) at 10 predefined temporal events for each trial were selected and the mean of each event were calculated and evaluated. Analyzed vertical GRF (VGRF) data could be divided into two different styles, one-legged and two legged. One-legged style shows good weight transfer to the target leg and most of the previous study shows this style as a typical pattern of good players. Therefore the data from the iron 5 swing obtained from 10 one-legged style golfers are provided as criteria for the evaluation of a swing.

• Asian-Australasian Journal of Animal Sciences
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• v.12 no.8
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• pp.1285-1291
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• 1999

A feeding trial was carried out over 238 days to determine the effect of compensatory growth in crossbred calves having 166 kg body weight. Fifteen crossbred calves were divided into two groups of five calves (G1 group) and ten calves (G2 group) as per randomized block design. Growth study was conducted on the feeding of wheat straw based diet containing 60 and 30 percent concentrate supplying equal amount of protein in group G1 and G2 respectively for 119 days (phase - I). At the end of phase-I, calves of G2 group were subdivided in to two groups (G3 and G4). One sub group (G4) received 60% concentrate in their diet (during 120 to 238 days of experiment) while other subgroup G3 received 30% concentrate in their diet (phase-II). The calves of G1 group continued to receive the same diet as during phase-I experiment. Mean DM intake was significantly higher in calves fed high level of concentrate (in G1 and G4 groups), which resulted in significantly higher digestibility of all nutrients except NDF. Nitrogen balance was positive in all the groups and showed significant differences in phase-II (higher nitrogen retention in G4 group than G1 group). ME intake was significantly affected by the level of dietary concentrate, being higher in high concentrate fed group (G1 and G4 than G2 and G3 group). Higher daily body weight gain in the calves of G4 group during phase-II than in G1 and G3 groups was due to compensatory growth on shifting animals from low concentrate to high concentrate based ration. Average daily body weight gain was higher in phase-I than in the phase-II. Protein and energy intake per unit body weight gain were significantly lower in calves fed high concentrate diet.

• Physical Therapy Rehabilitation Science
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• v.7 no.1
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• pp.41-47
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• 2018

Objective: To investigate the effect of performing three different toe touch (TT) task condition on the activities of four different muscles using surface electromyography (sEMG) in healthy young adults. Design: Cross-sectional study. Methods: A total of 20 healthy young adults (6 males, 14 females) voluntarily participated in this study. All subject randomly performed three different TT task conditions as follows: general toe-touch (GTT) task, one side toe touch (TT) task during weight bearing, and one side foward toe touch (FTT) task during weight bearing. The muscle activities of erector spinae (ES), gluteus maximus (GM), hamstring (HAM), tibialis anterior (TA) muscles during the TT task were measured using sEMG. Subject performed each of the three conditions three time in random order and mean values were obtained. Results: With the trunk flexion period, the TT and FTT showed significantly greater muscle activity in the GM, HAM and TA compared to the GTT task (p<0.05). The TT position showed significantly greater HAM muscle activity than the GTT position. The dominant and nondominant ES muscle activity was significantly greater in the FTT compared to the GTT position (p<0.05). The dominant GM, HAM, and TA was significantly greater in the TT and FTT compared to the GTT position (p<0.05). Although the dominant ES was significantly greater in the TT and FTT compared to the GTT position (p<0.05), the dominant GM muscle activity was signifcantly greater in the TT compared with the GTT position (p<0.05). Conclusions: These findings may be applicable within the clinical field for selective trunk and lower extremity muscle activation and basic biomechanics purpose.

• Journal of the Korean Society of Physical Medicine
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• v.3 no.2
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• pp.113-119
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• 2008

Purpose : In this case report, we demonstrated the improvement of gait ability on the child who has mental retardation with incomplete gait pattern. Methods : The subject was a 4 years old boy with mental retardation. We applied the Bobath approach to the subject. Treatments included to facilitate trunk alignment and stability, and to train weight bearing and shifting, to facilitate pelvis posterior-anterior movement, and to train walk especially stance phase and assist up-down stairs locomotion in environment similar to actual daily life. It was performed 24 sessions for 12 weeks. Results : With this treatment, he could accomplish dynamic standing stability and he could independent walk at the out door after 12 weeks. In gross motor function measure(GMFM), total motor function was improved to 85.6% from 75.7%. Conclusion : The gait ability of child with mental retardation was improved by using the bobath approach.