• 대한한방내과학회지
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• 제25권3호
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• pp.648-654
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• 2004

The following case study illustrates the administration of Bojanggunbi-tang in the treatment of a man diagnosed as having Crohu's disease. The usual gastrointestinal symptoms of Crohu's disease are diarrhea, abdominal pain and weight loss, in addition to anemia and rectal bleeding. A l6-year-old man diagnosed with Crohn's disease, who was treated at our clinic, had symptoms such as diarrhea, abdominal pain, weight loss, anemia and rectal bleeding. He was treated with Bojanggunbi-tang. For the two months the symptoms were considerably reduced. The result supports the clinical efficacy of Bojanggunbi-tang for the treatment of the symptoms of suspected Crohn's disease.

• 대한물리의학회지
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• 제15권3호
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• pp.61-68
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• 2020

PURPOSE: The purpose of this study was to investigate the current state of rapid weight loss and physical and mental complaints among elite combat athletes who were selected and trained as national representatives. METHODS: A total of 127 combat athletes who had trained at the national training center in 2019 were enrolled. The questionnaire used as the survey tool was interpreted as words that Korean athletes could easily understand based on the Portuguese version of the 'Rapid Weight Loss Questionnaire' (RWLQ). χ² tests was performed to determine the differences in physical and mental changes according to sports and weight loss method. RESULTS: Combat athletes in Korea regularly undergo rapidly weight loss within a short period of time prior to competition. There were statistically similar results in terms of weight loss method, physical and mental changes and information about weight loss according to the sport. Weight loss methods often limit food and water intake and dehydrate. The physical complaints associated with them are symptoms such as "no energy", "dizziness", and "muscle spasms". The mental complaints include "irritability", "concentration loss" and "anxiety". These symptoms can be caused by side effects such as food intake limitation, water restriction and dehydration. Information sources for weight loss were in the order of "senior or colleagues", "supervisor or coach", and "Internet". No information was obtained from a doctor or dietitian. CONCLUSION: These results provide a baseline for predicting proper weight loss in athletes and provide useful information for developing performance enhancement as well as weight loss.

• Annals of Clinical Neurophysiology
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• 제3권1호
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• pp.40-42
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• 2001

Anorexia nervosa(AN) is a disorder characterized by disturbance of body image, fear of gaining weight, severe weight loss and, in female, amenorrhea. Compared with normal persons, patients with AN have neuropathic symptoms more frequently. But electrophysiologic abnormalities have rarely been reported. We experienced a case with recurrent neuropathic symptoms after severe weight loss. Further evaluation revealed AN. Electrophysiologic study showed sensorimotor polyneuropathy and focal neuropathy with conduction block. As far as we know, this feature of neuropathy in AN has not been described. We describe unusual feature of neuropathy in our patient with literature review.

• 한국식품영양과학회지
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• 제28권5호
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• pp.1151-1157
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• 1999

The purpose of this study is to investigate the iron nutritional status and anemia of university female students. Seventy female subjects in Ulsan city were evaluated with questionnaire, measurement of hematological indices. The mean height and weight of 70 subjects were 160.76±0.48cm, 52.80±0.72kg and BMI(body mass index: kg/m2), %IBW(ideal body weight) were 21.0±0.29, 100.2±12.41. The mean values of hemoglobin(Hgb), hematocrit(Hct), serum iron(S Fe), serum ferritin(SF), TIBC(total iron binding capacity), transferrin saturation(TS(%)) and RBC were 12.7±11.10g/dl, 39.0± 2.61%, 96.9±41.98 g/dl, 28.9±24.78 g/dl, 369.6±54.36 g/dl, 27.1±12.40% and 4.4± 0.27(106/mm3), respectively. Iron deficiency anemia among the subjects was estimated as 15.7% by using Hgb(<12g/dl), 11.4% by Hct(<36%), 22.9% by S Fe(<60 g/dl), 34.3% by SF(<15 g/dl), 48.6% by TIBC(>360 g/dl) and 20.0% by TS(%)(<15%). 15 subjective symptoms were measured and the high prevalence symptoms were 'cold hands and feet' and 'tired out easily'. The correlation between hemotological indices and subjective symptoms was evaluated. The hemoglobin level was negatively correlated with 'cold hands and feet', 'short breath when climbing', 'fragile nail', 'inflammed inner mouth', 'pale face' and 'scaly tetter'.

• Molecular & Cellular Toxicology
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• 제5권2호
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• pp.153-159
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• 2009

In this study, we assessed the acute and subacute toxicity of Angelica gigas Nakai (A. gigas Nakai) extracts, which are comprised of decursin and decursinol angelate (D/DA) in rats. For the oral acute toxicity test, Sprague-Dawley (SD) male and female rats were gavaged with two doses of D/DA (200 and 2,000 mg/kg body weight) and then observed for any toxic symptoms for 2 weeks. The LD$_{50}$ value for the rats was greater than 2,000 mg/kg body weight for both male and female rats, which indicates that there were no toxic symptoms induced by doses of up to 2,000 mg/kg body weight. For the subacute toxicity study, rats were treated with D/DA at doses of 2 and 20 mg/kg body weight once a day for 30 days. There were no significant changes in body weight and food intake observed during the subacute toxicity study. In addition, no differences were observed between the control and treated groups when urinalysis was conducted or when hematology and biochemical parameters were evaluated. Finally, histopathological examination of the organs did not reveal any lesions in the control or treated groups. Taken together, these findings indicate that D/DA is safe and non-toxic.

• Journal of Acupuncture Research
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• 제31권3호
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• pp.25-33
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• 2014

Objectives : The purpose of this study is to evaluate the correlation between bone mineral density(BMD), age, weight, visual analog scale(VAS), menopausal rating scale(MRS), and to compare the difference between BMD, age, weight, VAS, MRS according to severity of the menopausal symptoms. Methods : The participants were 62 menopausal women diagnosed with osteoporosis who visited Cheonan Oriental Hospital, Daejeon University from December, 2011 to July, 2014. Age, weight, VAS, MRS were used as an evaluation tool. Results : 1. In all 62 cases of menopausal patients diagnosed with osteoporosis, the study found a statistically significant correlation between BMD and weight, while inverse correlation between BMD and MRS index. 2. Among menopausal patients with above 9 MRS index(group B), BMD and weight showed statistically significant correlation, while VAS and MRS index showed statistically significant inverse correlation. 3. Among group B, VAS were higher compared to control group(group A). Conclusions : This study showed that as patients with severer menopausal symptoms apt to show increased VAS and decreased BMD. Therefore, long-term follow-up in patients with menopausal syndrome is needed to improve the patients' quality of life.

• 대한한의학회지
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• 제37권3호
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• pp.39-46
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• 2016

Objectives: The present study aimed at investigating the effects of Schisandrae Fructus (SF) on menopause symptoms in ovariectomized mice. Methods: 6 weeks old female mice were ovariectomized (OVX), and the OVX mice were fed with a three doses of SF (25, 100, and 400 mg/kg, respectively) or $17{\beta}$-estradiol (E2, 0.5 mg/kg) 3 times a week for 6 weeks. Body weight was measured at every week and uterus weight was also measured at the end of experiment. Lipids and osteocalcin levels in serum were analyzed. Results: The uterine weight was not changed in SF treated group, while E2 intake increased the reduced uterine weight by OVX. Although Body weight was increased since two weeks after ovariectomy compared with sham operated group, there was no change in SF or E2 treated group compared with OVX. But LDL was significantly reduced in SF (400 mg/kg) or E2 fed mice and SF or E2 treatment decreased enhanced osteocalcin level by OVX. Conclusion: These results indicated that SF would be effective in the improvement of LDL level and osteoporosis on menopause.

• 한국식품영양과학회지
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• 제45권8호
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• pp.1083-1089
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• 2016

대부분의 여성은 폐경 이후 신체적 변화를 겪게 된다. 폐경의 증상으로는 홍조, 발한, 몸무게의 증가와 질 건조증 등이 있다. 본 연구에서는 여성의 폐경기 증상 완화에 효능이 있는 열 가지 종류의 생약을 조합하여 만든 혼합 추출물이 동물의 폐경 모델인 난소절제(ovariectomized, OVX) 레트에 어떠한 영향을 미치는지 알아보고자 하였다. 경구투여를 통해 각각 500 mg/kg/d, 1,000 mg/kg/d 농도의 열수 추출물(자음미단)을 8주간 섭취시켰으며, 양성대조군으로 에스트라디올($50{\mu}g/mL$)을 사용하였다. 실험을 통해 자음미단이 난소절제 레트에서 몸무게를 유의적으로 감소시켰으며, 간에서의 지방 함량 증가를 억제함을 확인하였다. 자음미단의 섭취는 페경 후 증가하는 혈액의 중성지방과 콜레스테롤 수치도 감소시켰다. 또한, 자음미단은 질의 무게를 증가시켰으며, 특히 질 내벽의 상피세포의 두께에 영향을 주었다. 자음미단의 1,000 mg/kg/d의 농도에서는 에스트로디올과 유사한 정도의 내벽 두께를 관찰할 수 있었다. 따라서 본 실험을 통해 자음미단이 폐경기 여성의 증상인 비만, 대사질환 및 질 건조증의 증상을 완화해줄 수 있으며, 이를 활용한 기능성 식품의 개발이 기대된다.

• Child Health Nursing Research
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• 제8권3호
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• pp.251-259
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• 2002

The purpose of the study was to investigate physical stress symptoms and health risk behaviors of adolescent athletes and high school students as a basis for providing a health promotion program of adolescent athletes. The subjects consisted of 160 male students of a physical education high school(athletes) in Kyonggi and 147 male high school students(non-athletes) in Seoul. Data was obtained from the physical stress symptoms and the health risk behaviors questionnaire. The result were as follows : 1. Physical stress symptoms didn't make significant difference between groups. GI symptom, as the subscale of physical stress symptoms of non-athletes were higher then those of athletes. The highest ranked physical stress symptoms in athletes was cardiopulmonary symptom Ⅱ(upper respiratory symptoms) and in non- athletes was central-neurological symptoms. 2. Health risk behaviors didn't make significant difference between groups. Weight control, as the subscale of health risk behaviors of athletes were higher then those of non-athletes. The highest ranked health risk behaviors in athletes was alcohol and in non-athletes was smoking. 3.There were the low positive correlation between physical stress symptoms and health risk behaviors.

• 여성건강간호학회지
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• 제4권3호
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• pp.388-401
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• 1998

The purpose of this study is to investigate the relationship between the eating disorder, physical symptoms and mood status among college women. Data has been analyzed by SPSS/PC using frequency, percentage, mean, standard deviation, t-test, Pearson correlation coefficient. The results of this study are as follows : 1. The mean of body weight and height of the subjects were 52.74kg, 163.10cm. 2. Depending upon BMI, the obesity subjects were very rare(2.2%) and the rest(97.8%) were underweight or normal. 3. The total mean score of anorexia nervosa was higher than bulimia nervosa. 4. The total mean score of perceived physical symptoms was 20.68 and subjects in this study showed the tendency giving the highest core on the item of autonomic nerve system and mensural status. 5. The total mean score of mood status was 58.49. 6. The scores of eating behavior differed significantly by the BMI : The score was highest in the group of normal body weighted(t=5.75, p<.05). 7. The scores of physical symptoms differed significantly by the BMI : The score was highest in the group of the underweight(t=7.35, p<.01). 8. No significant difference was found on over all mood status scores according to the BMI. 9. There was high positive correlation between BMI and eating disorder(r=.1633, p<.01), between eating disorder and physical symptoms(r=.2497, p<.0001), between eating disorder and mood status(r=.2328, p<.0001), and between symptoms and mood status(r=.5051, p<.0001). From the results of this study, the eating disorder among college woman was very serious and the perception of their body weight was distorted. Therefore, to prevent the eating disorder, professional intervention is needed.