• 제목/요약/키워드: Weight of evidence

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Spray Dried Animal Plasma as an Alternative to Antibiotics in Weanling Pigs - A Review -

  • Torrallardona, David
    • Asian-Australasian Journal of Animal Sciences
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    • 제23권1호
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    • pp.131-148
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    • 2010
  • Piglet health at weaning is compromised due to several stress factors. Following the ban of antibiotic growth promoters new alternatives are required to control these problems. This paper reviews the evidence available for the use of spray dried animal plasma (SDAP) as an alternative to antibiotics in weaning pigs. Data from 75 trials in 43 publications involving over 12,000 piglets (mean values) have been used to calculate the performance responses of piglets according to several factors including SDAP origin, protein source from the control diet being replaced, dose of inclusion, age and weight of the piglets at weaning, sanitary conditions and simultaneous use or not of medication. Although the use of SDAP of all origins results in positive responses, it appears that plasma from porcine origin has the highest efficacy. This could be explained by the specificity of its IgG against porcine pathogens. During the first week post-weaning the response to plasma appears to increase with the inclusion dose, although over the two-week pre-starter period an optimal inclusion level of 4-8% is suggested. SDAP improves feed efficiency more markedly when the piglets are challenged with an experimental infection or when feed does not contain medication, which could be indicative of a lower expenditure of energy and nutrients to build an immune response against the challenge. There is evidence supporting that SDAP IgG and other bioactive substances therein prevent the binding of pathogens to the gut wall and reduce the incidence of diarrhoea in the post-weaning phase. Overall, plasma can be postulated as an excellent alternative to in-feed antimicrobials for piglets in the post-weaning phase.

Evidence-Based Physical Therapy for Anterior Cruciate Ligament Injury: Literature Review

  • Lim, Hyoung won
    • The Journal of Korean Physical Therapy
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    • 제31권4호
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    • pp.161-168
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    • 2019
  • Most athletes with anterior cruciate ligament (ACL) ruptures undergo a surgical ACL reconstruction (ACLR) and rehabilitation. On the other hand, controversy still exists because neither a reconstruction nor rehabilitation have been proven to be superior in the management of ACL injury. This study reviewed the success rates of interventions to provide recommendations for the optimal management after an ACL injury. One of the most important considerations after an ACL injury is the timing and type of intervention. At the early stages, which involve the loss of volume and strength of quadriceps femoral muscle, weight bearing (closed kinetic chain) exercises with pain management followed by high velocity resistance exercises in an open kinetic chain environment are recommended to improve the quadriceps function. After that, it is important to apply intensive isokinetic exercise with a lower extension rate. In this case, it is important to apply overload to the muscles and to simultaneously lead the co-contraction of the hamstrings. Standards are essential because the timing and type of interventions are crucial to prevent re-injury and complications, such as osteoarthritis, as well as to confirm the successful outcome of the treatment. Different interventions recommended for ACL damage have yet to reach consensus. Further studies will be needed to observe the effects of the intervention through multidisciplinary approaches.

SPaRe: Efficient SQLite Recovery Using Database Schema Patterns

  • Lee, Suchul;Lee, Sungil;Lee, Jun-Rak
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제11권3호
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    • pp.1557-1569
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    • 2017
  • In recent times, the Internet of Things (IoT) has rapidly emerged as one of the most influential information and communication technologies (ICT). The various constituents of the IoT together offer novel technological opportunities by facilitating the so-called "hyper-connected world." The fundamental tasks that need to be performed to provide such a function involve the transceiving, storing, and analyzing of digital data. However, it is challenging to handle voluminous data with IoT devices because such devices generally lack sufficient computational capability. In this study, we examine the IoT from the perspective of security and digital forensics. SQLite is a light-weight database management system (DBMS) used in many IoT applications that stores private information. This information can be used in digital forensics as evidence. However, it is difficult to obtain critical evidence from IoT devices because the digital data stored in these devices is frequently deleted or updated. To address this issue, we propose Schema Pattern-based Recovery (SPaRe), an SQLite recovery scheme that leverages the pattern of a database schema. In particular, SPaRe exhaustively explores an SQLite database file and identifies all schematic patterns of a database record. We implemented SPaRe on an iPhone 6 running iOS 7 in order to test its performance. The results confirmed that SPaRe recovers an SQLite record at a high recovery rate.

Development and evaluation of continuing education course in renal nutrition

  • Karavetian, Mirey;Rizk, Rana
    • Nutrition Research and Practice
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    • 제10권1호
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    • pp.99-107
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    • 2016
  • BACKGROUND/OBJECTIVE: Competent renal dietitians are crucial for better patient compliance and clinical outcomes, specifically in critical settings. The aim of this study was to develop and evaluate an evidence-based course in renal dietetics for dietitians working in health care systems where dietetic specialization is absent. SUBJECTS/METHODS: Fifteen licensed dietitians working with hemodialysis patients in Lebanon were randomly recruited to participate in the course. The latter was developed by the study's primary investigator, according to evidence-based practice guidelines, and focused on all aspects of renal nutrition. Total course duration was 28 hours spread over a 2 month period. Dietitians' knowledge in renal nutrition was tested pre- and post-training through a 23-item questionnaire; the total score was expressed in percentage (< 60% score indicated insufficient knowledge). Paired-samples t test was used for statistical analysis. RESULTS: Overall knowledge of the dietitians significantly improved post-training and reached satisfactory levels (pre: $38.75{\pm}17.20%$, post: $62.08{\pm}21.85%$). Sub-analysis of the change in the knowledge showed significant and satisfactory improvement only in 3 topics: 1) correct body weight use in calculations, 2) energy estimation method and 3) phosphorus management. Knowledge in the fluid management significantly improved but did not achieve a satisfactory level. CONCLUSION: The course significantly improved dietitians' knowledge in renal nutrition. If adopted as part of the continuing education of dietitians in countries that lack dietetic specializations, it may serve the first step towards improving health care practice.

국민 건강증진을 위한 신체활동 지침 (Health-enhancing Physical Activity Guidelines for Koreans: the Status and Directions for Revision)

  • 김완수
    • 보건교육건강증진학회지
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    • 제26권2호
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    • pp.103-117
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    • 2009
  • Objectives: There have been no specific as well as evidence-based physical activity guidelines issued on the governmental level. There just have been physical activity recommendations and guidelines released from governmental agencies or organizations as well as individual researchers and these are not consistent, thereby giving the public and even some professionals quite a confusion. As such, this study was aimed to suggest key factors to include when issuing national physical activity recommendations for Koreans. Methods: Since chronological evolution of modern physical activity recommendations reflects key factors to consider when establishing those recommendations and guidelines, that released for several decades was reviewed. Results: The evolution was found to be based on the basis of strong evidence from both epidemiological and exercise physiology studies and the key concepts of such evolution were feasibility, efficacy, and safety. Conclusion: On the basis of three key factors found in the review process, this study concluded that the upcoming national physical activity guidelines should include the following to maximize the outcomes of the efforts which have long been put by the division of physical activity under the 'New Health Plan 2010'. First, guidelines for achieving health benefits (ie, preventing chronic diseases such as cardiovascular disease, diabetes, and cancers or weight management) as well as improving cardiorespiratory fitness should be included to enhance efficacy. Second, safety measures should be included to enhance safety. Third, various alternative forms of physical activity should be included to enhance feasibility.

출생시 체중변화의 양상과 산모의 연령 및 출산순위와의 관계 (Changing Pattern of Birth Weight and Relationship of Birth Weight with Maternal Age and Parity)

  • 박정한;신봉선
    • Journal of Preventive Medicine and Public Health
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    • 제20권2호
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    • pp.322-330
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    • 1987
  • 출생시 체중변화의 양상과 산모의 연령 및 출산순위와의 관계를 알아보기 위하여 1977년 1월부터 1986년 12월까지 부산시내 1개 종합병원에서 총 14,346건의 분만 가운데 20주이후에 출생한 단태아 13,634명을 대상으로 산실의 분만대장에서 신생아의 출생순위분포, 산모의 연령분포, 신생아의 체중분포와 평균체중, 산모의 연령과 출산순위에 따른 저 체중아와 과체중아의 출생을, 유산경험율과 사산율을 조사하였다. 신생아의 평균체중은 1979년에는 남아 3074gm, 여아 2985gm에서 1986년에는 남아 3266gm, 여아 3210gm 으로 증가하였고, 저체중아의 발생율은 1977년 7.2%에서 점차 증가하여 1980년에는 10.4%였으나 그후 점점 감소하여 1986년에는 6.5%였다. 과체중아의 발생율은 2,9%에서 4.6%사이로 평균 3.9%였으며 특별한 변화 양상은 볼 수 없었다. 유산을 경험 한 산모의 비율은 1979년에 51.6%에서 1986년에는 45.1%로 감소하였고, 사산율도 1977년에는 2.6%에서 1986년에는 1.5%로 감소했다. 이와같은 변화에는 가족계획 실천율의 증가와 결혼연령의 상승으로 $25{\sim}34$세사이 산모의 1과 2순위 출생아가 차지하는 비율이 증가한 것이 크게 영향을 미친 것으로 생각되며, 과체중아의 비율은 늘지 않고 오히려 저체중아의 출생율은 감소되어 전체적으로 신생아의 건강이 향상되고 있는 것으로 나타났다.

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Evidence-based customized nutritional intervention improves body composition and nutritional factors for highly-adherent children and adolescents with moderate to severe obesity

  • Kim, Jieun;Kim, YoonMyung;Seo, Young-Gyun;Park, Kyung-Hee;Jang, Han Byul;Lee, Hye-Ja;Park, Sang Ick;Lim, Hyunjung
    • Nutrition Research and Practice
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    • 제14권3호
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    • pp.262-275
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    • 2020
  • BACKGROUND/OBJECTIVES: Evidence-based customized nutritional interventions are required for effective treatment of moderate to severe obese children and adolescents. SUBJECTS/METHODS: Sixty six (64.1% of 103) of the eligible participants who joined the usual care or physical activity group in the clinic were involved in 16-week intervention. Customized nutritional intervention was implemented for each participant based on a nutrition care process (NCP) model. Sociodemographic assessment, anthropometrics data, health- and dietary-related behaviors, and dietary intake of the study subjects were assessed at baseline and follow-up. All participants engaged in 30-minute nutritional sessions on a monthly basis. RESULTS: After 16 weeks, there were significant improvements in body composition [BMI (-0.8 ± 0.9, P < 0.05), BMI z-score (-0.3 ± 0.2, P < 0.001), body fat (kg) (-1.3 ± 2.1, P < 0.05), and body fat (%)(-1.5 ± 1.9, P < 0.05)] as well as macronutrient intake [total energy intake (kcal) (-563.7 ± 656.8, P < 0.05), energy (%) (-26.5 ± 30.0, P < 0.05) and fat (g) (-28.3 ± 40.6, P < 0.05)] in the adherent group than the non-adherent group. The SOC was higher in both groups after the intervention (P < 0.001). CONCLUSIONS: Our results highlight the positive effects of an evidence-based approach as a multidisciplinary intervention for people-centered nutritional care and weight management.

Psychosocial support interventions for women with gestational diabetes mellitus: a systematic review

  • Jung, Seulgi;Kim, Yoojin;Park, Jeongok;Choi, Miyoung;Kim, Sue
    • 여성건강간호학회지
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    • 제27권2호
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    • pp.75-92
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    • 2021
  • Purpose: This study aimed to analyze the content and effectiveness of psychosocial support interventions for women with gestational diabetes mellitus (GDM). Methods: The following databases were searched with no limitation of the time period: Ovid-MEDLINE, Cochrane Library, Ovid-Embase, CINAHL, PsycINFO, NDSL, KoreaMed, RISS, and KISS. Two investigators independently reviewed and selected articles according to the predefined inclusion/exclusion criteria. ROB 2.0 and the RoBANS 2.0 checklist were used to evaluate study quality. Results: Based on the 14 selected studies, psychosocial support interventions were provided for the purpose of (1) informational support (including GDM and diabetes mellitus information; how to manage diet, exercise, stress, blood glucose, and weight; postpartum management; and prevention of type 2 diabetes mellitus); (2) self-management motivation (setting goals for diet and exercise management, glucose monitoring, and enhancing positive health behaviors); (3) relaxation (practicing breathing and/or meditation); and (4) emotional support (sharing opinions and support). Psychosocial supportive interventions to women with GDM lead to behavioral change, mostly in the form of self-care behavior; they also reduce depression, anxiety and stress, and have an impact on improving self-efficacy. These interventions contribute to lowering physiological parameters such as fasting plasma glucose, glycated hemoglobin, and 2-hour postprandial glucose levels. Conclusion: Psychosocial supportive interventions can indeed positively affect self-care behaviors, lifestyle changes, and physiological parameters in women with GDM. Nurses can play a pivotal role in integrative management and can streamline the care for women with GDM during pregnancy and following birth, especially through psychosocial support interventions.

Survey on Value Elements Provided by Artificial Intelligence and Their Eligibility for Insurance Coverage With an Emphasis on Patient-Centered Outcomes

  • Hoyol Jhang;So Jin Park;Ah-Ram Sul;Hye Young Jang;Seong Ho Park
    • Korean Journal of Radiology
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    • 제25권5호
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    • pp.414-425
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    • 2024
  • Objective: This study aims to explore the opinions on the insurance coverage of artificial intelligence (AI), as categorized based on the distinct value elements offered by AI, with a specific focus on patient-centered outcomes (PCOs). PCOs are distinguished from traditional clinical outcomes and focus on patient-reported experiences and values such as quality of life, functionality, well-being, physical or emotional status, and convenience. Materials and Methods: We classified the value elements provided by AI into four dimensions: clinical outcomes, economic aspects, organizational aspects, and non-clinical PCOs. The survey comprised three sections: 1) experiences with PCOs in evaluating AI, 2) opinions on the coverage of AI by the National Health Insurance of the Republic of Korea when AI demonstrated benefits across the four value elements, and 3) respondent characteristics. The opinions regarding AI insurance coverage were assessed dichotomously and semi-quantitatively: non-approval (0) vs. approval (on a 1-10 weight scale, with 10 indicating the strongest approval). The survey was conducted from July 4 to 26, 2023, using a web-based method. Responses to PCOs and other value elements were compared. Results: Among 200 respondents, 44 (22%) were patients/patient representatives, 64 (32%) were industry/developers, 60 (30%) were medical practitioners/doctors, and 32 (16%) were government health personnel. The level of experience with PCOs regarding AI was low, with only 7% (14/200) having direct experience and 10% (20/200) having any experience (either direct or indirect). The approval rate for insurance coverage for PCOs was 74% (148/200), significantly lower than the corresponding rates for other value elements (82.5%-93.5%; P ≤ 0.034). The approval strength was significantly lower for PCOs, with a mean weight ± standard deviation of 5.1 ± 3.5, compared to other value elements (P ≤ 0.036). Conclusion: There is currently limited demand for insurance coverage for AI that demonstrates benefits in terms of non-clinical PCOs.

돼지 염색체상의 IGF II 유전자 인접 부위에서 번식 및 성장형질에 연관된 Imprinting 양적형질 유전자 좌위(QTL)의 탐색 (Detection of Imprinted Quantitative Traits Loci (QTL) for Reproductive and Growth Traits in Region of IGF II Gene on fig Chromosome)

  • Lee, Hakkyo
    • 한국가축번식학회지
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    • 제25권4호
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    • pp.295-304
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    • 2001
  • 양적형질 유전자 좌위 (QTL)의 탐색과 이들의 발현 양상 규명을 위해 Berkshire종과 Yorkshire종 간의 교배를 통해 생산된 F$_2$ 실험집단에서 regression interval mapping이 이루어졌다. 모두 525마리의 F$_2$ 자손들에서 일당 증체량, 평균 등지방 두께, 배장근 단면적이 표현형으로 조사되어 분석에 이용되었으며 모돈의 번식능력에 관련된 QTL 존재 여부 추정을 위해 간접 형질로 인정되고 있는 생시체중과 이유 시 체중을 분석에 포함하였다. 양적형질의 분리 여부를 추론하기 위하여 돼지의 2번 염색체에서 8종의 microsatellite 표지인자가 선택되어 유전자형이 조사되었다. 각각의 유전적 모델에서 산출된 통계량으로부터 QTL 존재 여부와 특정 QTL 발현 양상에 대한 여부를 나타낼 수 있는 인정되는 수준의 type I 오차율을 제어할 수 있는 임계값 (threshold)을 permutation test에 의해 제시하였다. QTL의 존재와 그 QTL의 Imprinting 여부는 부계와 모계를 통해 원가계 1세대의 대립유전자가 전달되는 과정에서 발현되는 특성을 분리시키는 통계적 의형을 설정하여 검정 통계량을 산출하였다. 분석에 이용된 3가지 형질과 연관된 3종류의 QTL 존재 가능성을 돼지의 2번 염색체에서 확인하였으며, 이들 중 평균 등지방 두께와 배장근 단면적에 각각 영향을 미칠 것으로 추론된 2종류의 QTL 발현은 정상적인 Mendelian 유전양식을 따르지 않고 imprinting된다는 증거를 얻어냈다. 또한 이들 imprinting되는 QTL은 이미 imprinting 표현 양식을 가진다고 알려진 IGF II 유전자의 위치와 거의 동일한 염색체강의 지점에서 부계로 전달되는 QTL만이 발현되는 특징을 보이는 것으로 밝혀졌다. 한편 Mendelian 모형과 imprinting 모형 모두에서 유의적인 임계값 이상을 보이는 검정 통계량이 산출된 일당 증체량 연관 QTL은 두 모형간의 적정성 분석을 위한 검정을 퐁해 Mendelian 양식을 따른 것으로 최종 확인되었다.

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