• The Journal of Korean Medical History
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• v.15 no.2
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• pp.117-134
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• 2002

"Gup Yu Bang" is the first Korean book that specialized in pediatrics. It was written by Jo Jeong-jun on the 25th year of King Young Jo in the Choson dynasty. He quoted a lot of information from "Yi-Hak-Yip-Mun" by Yi-cheon in the Myung dynasty and "Xiao Er Yao Zheag Zhi Jue" by Qian Yi in the Song dynasty, but he added his own opinions and clinical experiences to the book. In addition to that, the book explains not only symptoms and prescriptions but also the etiology and pathology of children's diseases. In particular, he showed a great deal of creativity in his book called "Dong Bang Six Fu's Qi Principle" After studying "Gup Yu Bang", I have drawn the following conclusions. 1. Prevention is more important than treatment in pediatrics. 2. When we make a diagnosis, facial inspection has priority. 3. In terms of treatmemt, Wu zang is a general rule. Therefore, we should focus on Wu zang and Pi Wei. 4. The following terms definition symptom cause prescription clinical example prevention are to be explained with reference to the nature or symptoms of the disease. 5. We can see that smallpox was more widspread than the measles in the period of King Young Jo. 6. Even though he was influenced by "Yi-Hak-Yip-Mun", "Xiao Er Yao Zheag Zhi Jue", and "Dong eui bo gam", his own explanation is clearer in his book called "Gup Yu Bang" which is based on his own clinical experiences. 7. "Gup Yu Bang" is a practical and experiential book.

• Journal of Oriental Neuropsychiatry
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• v.10 no.1
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• pp.147-157
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• 1999

In order to confirm the efficiency of Oriental medical treatment on Vascular dementia, 24 probable and possible vascular dementia patients diagnosed by ADDTC criteria, were chosen and followed among the patients who had visited KOMC from April, 1996 to March, 1997. They were given herbal and acupuncture therapy, mainly focused on circulating qi(順氣)and removing phlegm(治痰) which is generally applied in early stage of cerebro-vascular disease, and then assessed by the improvement of stage according to the level of impairment, as proposed by APA. The results were as followed. 1. Out of 25 cases, 8 patients showed 2 grade improvement(++), 15 patients showed 1 grade improvement(+), and 1 patient showed no change. 2. The efficiency of treatment is higher when they're given treatment earlier. 3. The efficiency of treatment is higher when their symptoms are lighter. In conclusion, this study shows meaningful effect of Oriental medical treatment on vascular dementia and also shows that It's more effective in the case of short onset and mild symptom.

• Journal of Oriental Neuropsychiatry
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• v.19 no.3
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• pp.205-217
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• 2008

After recovery from acute carbon monoxide poisoning, some patients suffer from neuropsychiatric problems such as cognitive impairement, movement disorder, change of personality and mental disorder after lucid interval in which the patient has no symptom. This sequela of carbon monoxide poisoning is called delayed post-anoxic encephalopathy(DPE). No neuroprotective drug has yet demonstrated ecfficacy and hyperbaric oxygen treatment's effect have little scientific evidence in preventing and improving DPE. In such situation, korean traditional treatment may be helpful in treating the patient suffering from DPE. In this case report, we will describe the patient that has suffered from severe DPE involving cognitive impairment, gait disturbance and incontinence but has been improved successfully by korean traditional medicine treatment, especially Jowiseungchungtang. This case could present how we will study about DPE.

• Journal of Oriental Neuropsychiatry
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• v.16 no.2
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• pp.159-169
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• 2005

Amyotrophic lateral sclerosis (ALS) is characterised by progressive impairment of motor functions up to a complete loss of autonomy, and most of ALS patients are associated with the total preservation of mental state like depression. A patient in this case report had ALS and during progress of ALS had undergone depression and Hwabyung's Symptoms. This patient was treated with herb medication, acupuncture, psychotherapy(relaxation & councelling) primarily. During the 18 days of treatment from admission, the patient experienced much improvement of depression and Hwabyung's Symptoms. and ALS's symptom like weakness & numbness of lower limb had improved considerably, too.

• The Journal of Korean Oriental Chronic Disease
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• v.10 no.1
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• pp.53-61
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• 2005

Guillain-Barre syndrome (GBS) is a group of autoimmune syndromes consisting of demyelinating and acute axonal degenerating forms of the disease. Typically, Gullain-Barre syndrome can be diagnosed from the patient's symptoms and physical examination such as the rapid onset of weakness, paralysis and loss of reflexes. In most patients, resolution is complete or near complete. Treatment consists of supportive care, ventilatory management (in about one third of patients), and specific therapy with intravenous immunoglobulin or plasmapheresis. This clinical report is about suspected acute severe Guillain-Barre syndrome patient, 61-year-old man had quadriplegia, facial palsy, dysphasia, respiratory failure. After 5 weeks of East-West integrative medicine therapy - Conventional Conservative therapy(plasmaphresis and intravenous immunoglobulin) and Korean traditional medicine(Sasang medicine and acupuncture treatment) - most symptoms improved.

• Journal of Acupuncture Research
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• v.31 no.4
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• pp.155-162
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• 2014

Objectives : The purpose of this study is to report the effect of Korean medical treatment on a patient with relapsing transverse myelitis. Methods : The patient was treated using acupuncture, pharmacopuncture, herbal medicine and other treatments including moxibustion and therapeutic exercise for 8 weeks. We evaluated the patient's motor grade with medical research council(MRC) scale and evaluated active range of motion in the hip, knee, and anke joint. Results : Through treatment the patient's motor grade and active range of motion all improved. Other symptoms such as lower limb hypoesthesia and residual urine sensation also showed improvement. Conclusions : We concluded that Korean medicine treatment had respectable effect in improving symptoms on the patient with relapsing transverse myelitis.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.2
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• pp.691-694
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• 2013

Purpose: By carrying out a meta-analysis of randomized controlled trials that compared sorafenib or combined chemotherapy with placebo or combined chemotherapy, the effectiveness of sorafenib in hepatocellular carcinoma was evaluated in the present study, which also provided clinical practice guidelines of evidence-based-medicine. Methods: We reviewed PubMed citations concerning sorafenib treating hepatocellular carcinoma in randomized controlled trials from Jan 2000 to July 2012. All the literature was extracted by Cochrane systematic reviews and underwent meta-analysis with RewMan 5.0 software. Results: Finally, four papers documenting randomized controlled studies were included. Compared with controls, sorafenib was shown to significantly increase overall survival (OS), time to progression (TTP), and disease control rates (DCR), but not the time to symptom progression (TTSP) in hepatocellular carcinoma patients. The incidence of grade-III/IV adverse reactions, including hand-foot-skin reactions, diarrhea, hypertension and skin rash or desquamation, in sorafenib treatment group was higher than that in controls. However, there was no significant difference in the incidence of hypodynamia between the two groups. Conclusions: Sorafenib exerts significant curative effects in hepatocellular carcinoma.

• Journal of Acupuncture Research
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• v.32 no.1
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• pp.133-140
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• 2015

Objectives : The purpose of this study is to report a case of Brown-Sequard syndrome caused by traumatic cervical fracture, presenting pain in the right upper extremity and back of the left hand, motor weakness in the right side and diminished pain and temperature in the left side. Methods : A patient received Korean medical treatment(acupuncture, electroacupuncture, herbal medicine, cupping, moxibustion, Silver Spike point electrotherapy(SSP)) and rehabilitation treatment. We evaluated pain with the Numeric Rating Scale(NRS), motor grade with a Medical Research Council(MRC) scale, sensory function and Modified Barthel Index(MBI). Results : After treatment, the patient showed considerable improvement in NRS, motor & sensory function, and MBI. Conclusions : Korean medical and rehabilitation treatments could be effective for Brown-Sequard syndrome patients. More extensive studies should be carried out.

• Parasites, Hosts and Diseases
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• v.57 no.3
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• pp.291-294
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• 2019

Primary amebic encephalitis (PAM) is a devastating central nervous system infection caused by Naegleria fowleri, a free-living amoeba, which can survive in soil and warm fresh water. Here, a 43-year-old healthy male was exposed to warm freshwater 5 days before the symptom onset. He rapidly developed severe cerebral edema before the diagnosis of PAM and was treated with intravenous conventional amphotericin B while died of terminal cerebral hernia finally. Comparing the patients with PAM who has similar clinical symptoms to those with other common types of meningoencephalitis, this infection is probably curable if treated early and aggressively. PAM should be considered in the differential diagnosis of purulent meningoencephalitis, especially in patients with recent freshwater-related activities during the hot season.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.14 no.1
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• pp.61-76
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• 2019

Objectives : The purpose of this study was to report the clinical results of various medical methods (including Chuna joint mobilization) used to treat a single patient with polyneuritis. Methods : We treated a 46 year-old female patient diagnosed with polyneuritis using various methods, including acupuncture, moxibustion, infrared therapy, herbal medication, Western medication, Chuna manual therapy, and physical therapy. We evaluated the results using the numeric rating scale (NRS), manual muscle test (MMT), active range of motion (ROM), modified barthel index (MBI). Other evaluation scale included Deep tendon reflex and thickness of muscle especially forearm and lower leg. Results : Following treatment using a combination of the above methods, the general overall condition of the patients was significantly improved. Furthermore, the NRS, MMT, MBI, and the active ROM scores were numerically improved. Conclusions : In this case, a single patient with polyneuritis was treated using a combination of Korean and Western medical methods. Although this study provides useful insight into treatment methods, further studies are required to determine the treatment effects of Korean medicine, specifically Chuna manual therapy, in patients with polyneuritis.