• 제목/요약/키워드: Weekly report

검색결과 54건 처리시간 0.023초

큰 두위를 주소로 내원하여 헌터 증후군으로 일찍 진단된 증례 1례 (A Case of Early Diagnosed Hunter Syndrome Detected by Large Head on Routine Examination)

  • 이승호;박우성;이영석;유지숙
    • 대한유전성대사질환학회지
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    • 제14권2호
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    • pp.156-162
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    • 2014
  • A 25-month-old boy was referred to the hospital due to large head detected on routine physical examination. At visit, dysmorphic facial appearances, including broad nose, prominent forehead, and coarse face, were noted. Nasal obstruction with nasal voice, prominent adenoids, and bilateral middle ear effusions were detected. His abdomen was distended, and liver and spleen were palpated about 3 finger and 2 finger breadths, respectively. He was operated for bilateral inguinal hernias. The motion of both elbow joints was mildly limited on supination and pronation. Urinary level of glycosaminoglycan was elevated and the enzyme activity of iduronate sulfatase in leukocytes was decreased. The mutational analysis of the gene iduronate 2-sulfatase (IDS) revealed c.263G>A (p.Arg88His) mutation. His developmental scale showed delayed development and there was cardiac valvular involvement (tricuspid regurgitation and mitral valve prolapse). After the diagnosis of Hunter syndrome, enzyme replacement therapy started on a weekly basis without progression of any clinical features. Here we report a case of early diagnosed Hunter syndrome detected by large head on routine examination. Thus, it is important to associate Hunter syndrome in the patient with large head especially, if there is the history of bilateral inguinal hernia and prominent adenoids to increase the possibility of early diagnosis and treatment.

저출력 레이저 조사에 의한 창상의 통증완화 및 치유조장 -증례 보고- (Pain Relief and Accelerated Healing Processes of Wound by Low Level Laser Irradiation(Case Report))

  • 이태현;손덕희;김봉일;조성경;이상화
    • The Korean Journal of Pain
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    • 제7권1호
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    • pp.74-77
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    • 1994
  • 통증치료 목적으로 구입한 본 HI-TECH 50으로 급만성 피부창상에 조사한 결과 통증완화 뿐만 아니라 창상치유에 좋은 성과를 얻었다. 특히 고질적 만성 당뇨병성 피부궤양같이 보존적 치료법으로 극히 치유가 어려운 경우에 레이저 광선을 조사함으로 해서 육아조직의 활성화는 물론이고 진통효과와 피부이식의 성공율도 현저히 향상되었음을 관찰하였다.

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Protective effect of lectin from Synadenium carinatum on Leishmania amazonensis infection in BALB/c mice

  • Afonso-Cardoso, Sandra R.;Rodrigues, Flavio H.;Gomes, Marcio A.B.;Silva, Adriano G.;Rocha, Ademir;Guimaraes, Aparecida H.B.;Candeloro, Ignes;Favoreto, Silvio;Ferreira, Marcelo S.;Souza, Maria A. de
    • Parasites, Hosts and Diseases
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    • 제45권4호
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    • pp.255-266
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    • 2007
  • The protective effect of the Synadenium carinatum latex lectin (ScLL), and the possibility of using it as an adjuvant in murine model of vaccination against American cutaneous leishmaniasis, were evaluated. BALB/c mice were immunized with the lectin ScLL (10, 50, 100$[\mu}g$/animal) separately or in association with the soluble Leishmania amazonensis antigen (SLA). After a challenge infection with $10^6$ promastigotes, the injury progression was monitored weekly by measuring the footpad swelling for 10 weeks. ScLL appeared to be capable of conferring partial protection to the animals, being most evident when ScLL was used in concentrations of 50 and 100${\mu}g$/animal. Also the parasite load in the interior of macrophages showed significant reduction (61.7%) when compared to the control group. With regard to the cellular response, ScLL 50 and 100 ${\mu}g$/animal stimulated the delayed-type hypersensitivity (DTH) reaction significantly (P < 0.05) higher than SLA or SLA plus ScLL 10 weeks after the challenge infection. The detection of high levels of IgG2a and the expression of mRNA cytokines, such as IFN-$\gamma$, IL-12, and TNF-$\alpha$ (Th1 profiles), corroborated the protective role of this lectin against cutaneous leishmaniasis. This is the first report of the ScLL effect on leishmaniasis and shows a promising role for ScLL to be explored in other experimental models for treatment of leishmaniasis.

봉약침 치료를 중심으로 한 한방 복합치료로 호전된 당뇨병성 신경병증 환자 1례 (A Case Report on Diabetic Neuropathy Treated with Bee Venom Acupuncture and Combined Korean Medicine)

  • 전규리;임태빈;황예채;최정우;박성욱;박정미;고창남;조승연
    • 대한한방내과학회지
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    • 제42권5호
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    • pp.958-966
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    • 2021
  • Objective: This study investigated the effectiveness of bee venom acupuncture for a diabetic neuropathy patient. Methods: A diabetic neuropathy patient received twenty-one bee venom acupuncture treatments for a total of 99 days. The Neuropathy Pain Scale (NPS) was used to evaluate the weekly peak pain during the treatment period. Results: After the treatments, the NPS scores improved, and the frequencies of peak pain decreased. Conclusions: This clinical case indicates that bee venom acupuncture combined with Korean medicine may be effective for treating diabetic neuropathy patients.

동절기 대파 재배지 파총채벌레 발생 보고 (Report on an Outbreak of the Onion Thrips, Thrips tabaci, Infesting Welsh Onion during Winter Season)

  • 김철영;최두열;김용균
    • 한국응용곤충학회지
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    • 제60권2호
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    • pp.247-254
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    • 2021
  • 동절기(1 ~ 2월) 시설재배지 대파에 파총채벌레(Thrips tabaci)가 발생하였다. 파총채벌레의 동정은 트랩에 포획된 개체의 DNA 바코드를 중심으로 확인하였다. 주별 파총채벌레 발생은 끈끈이판 하나당 약 240 ~ 700 마리의 포획 밀도를 나타냈다. 포획 효율은 트랩 색상에 따라 차이를 보여 황색이 청색 트랩에 보다 우수하였다. 또한 대부분(90% 이상) 대파는 이들 파총채벌레의 식흔을 보였다. 이러한 파총채벌레 발생은 특정 비닐하우스에 국한되었다. 이러한 국부적 파총채벌레의 발생 양상을 분석하고자 이들 행동을 실내외에서 관찰하였다. 실내 분석은 약 1.5 mm 정도 몸길이의 성충이 약 5 cm 까지 도약하였다. 야외에서는 이들 성충이 시설재배지 최대 높이인 2 m 까지 비행 행동을 보였다. 이러한 비행 행동은 인근(2 m 이내) 시설재배지까지 이동이 가능할 것으로 추정되었으나 실제로 전파되지 않은 것은 야외 저온 조건이 물리적 장벽을 제공하여 준 것으로 해석되었다. 따라서 겨울기간 파총채벌레의 대발생은 특정 소지역에 국한되었다.

NCS 의사소통능력과 연계된 부사관과의 자료통합적 문서 교육 연구 (The Study of Integrated Document Training Materials Related to NCS Communication Ability for Petty Officer Majors)

  • 유용태
    • 융합보안논문지
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    • 제19권2호
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    • pp.137-146
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    • 2019
  • 본 연구는 NCS 의사소통능력과 부사관과 의사소통 교육의 연관성을 규명하여 교육목표와 성취 수준에 대하여 고찰하고 이에 적합한 자료통합적 문서 교육에 대하여 살펴보고자 한다. 부사관과 의사소통 교육의 목표는 실질적인 부사관의 의사소통 상황과 연관성을 지닌 문서이해능력과 문서작성능력을 함양하는 것이며 이에 대한 '중' 이상의 성취 수준을 달성하는 것이다. 교육구성은 부사관과의 특성을 고려하여 하위능력 요소에 따른 주차별 세부사항으로 설계하여 교육목표와 수준을 달성하도록 구성하였다. 이에 적합한 부사관과 자료통합적 문서 교육은 문서의 주제제시-팀 활동-최종활동보고서 제출이라는 3단계로 이루어지며 지속적인 평가지를 작성하여 성취 수준을 확인할 수 있도록 구성하였다. 자료통합적 문서 교육은 NCS의 중요성이 강조되는 시점에서 NCS와 연계된 부사관과의 의사소통 교육방안을 제시한 것이다. 앞으로 부사관과 학생들의 문서작성 역량 향상을 모색할 수 있는 다양한 논의가 진행되기를 기대한다.

에릭슨의 발달단계 이론에 따른 4세 여아의 놀이치료에 나타난 놀이 분석 (Play Analysis of the Play Therapy conducted for a 4-year-old girl on the basis of Erikson's Psychosocial Development)

  • 전혜진;유미숙
    • 한국놀이치료학회지
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    • 제21권4호
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    • pp.449-471
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    • 2018
  • 본 연구는 도구적 사례연구로 만 4세 여아의 놀이치료 과정에 나타난 놀이를 분석하였다. 내담 아동은 어린이집에서 집단 활동에 참여하는 것을 어려워하고 낯선 사람이 말을 걸면 울어버리는 것을 주 호소로 하여 놀이치료에 의뢰되었다. 치료적 개입으로 아동에 대한 개별 놀이치료와 회기 후 10분 모(母) 상담이 제공되었고, 모 상담은 촉진적인 양육 기술과 양육 환경을 조성하는 방향으로 진행되었다. 또한 매주 담임 교사가 아동의 어린이집 생활 모습을 관찰하고 매주 관찰척도를 작성하였다. 총 12회기(주 2회, 6주)가 실시되었으며 종료 후 한 달이 지난 시점에 추수 회기가 진행되었다. 이에 따라 유아의 놀이치료 과정에 나타난 매 회기 치료 장면을 제시하고 Erikson의 발달 이론에 기초하여 놀이를 분석하였다. 이를 통하여 유아의 놀이치료 과정을 이해하고자 할 때 기초 자료를 제공하였다는데 의의가 있다.

Late-onset drug resistant epilepsy in an adolescent with Allan-Herndon-Dudley syndrome

  • Soyoung Park;Young-Lim Shin;Go Hun Seo;Yong Hee Hong
    • Journal of Genetic Medicine
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    • 제21권1호
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    • pp.31-35
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    • 2024
  • Allan-Herndon-Dudley syndrome (AHDS) is a rare X-linked neurodevelopmental disorder with abnormal thyroid function caused by mutation in the solute carrier family 16 member 2 (SLC16A2) gene. Clinical manifestations of AHDS are global or axial hypotonia, a variety of movement disorders, severe intellectual disability, quadriplegia or spastic diplegia, growth failure, and seizures. A 10-year-old boy visited our hospital with the chief complaint of newly onset generalized tonic seizures with vocalization of weekly to daily frequency. He showed early infantile hypotonia, severe intellectual disability, and frequent respiratory infections. He could not walk independently and was non-verbal. Electroencephalogram revealed generalized slow spike and waves with multifocal spikes and slow background rhythms. His tonic seizures were controlled with more than two anti-seizure medications (ASMs). At 11 years of age, he was evaluated for thyroid function as part of regular screening for ASM maintenance and was found to have abnormal thyroid function. We performed whole exome sequencing for severe global developmental delay, drug-resistant epilepsy, and abnormal thyroid function. The hemizygous c.940C>T (p.Arg314Ter) variant in the SLC16A2 gene (NM_006517.5) was identified and confirmed based on Sanger sequencing. Herein, we describe a case of an AHDS patient with late-onset drug-resistant epilepsy combined with congenital hypotonia, global developmental delay, and abnormal thyroid function results. To the best of our knowledge, this is the oldest adolescent among AHDS cases reported in Korea. In this report, clinical characteristics of a mid-adolescence patient with AHDS were presented.

반코마이신 내성 장구균 감염 환자에 대한 한의치험 1례 (A Case of Vancomycin-Resistant Enterococci Infection Treated with Korean Medicine)

  • 이다빈;성시윤;홍성희;황예채;김경묵;이한결;문상관;정우상;권승원
    • 대한한방내과학회지
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    • 제45권2호
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    • pp.167-175
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    • 2024
  • Hospital-acquired bacterial infections, including vancomycin-resistant enterococci (VRE) infection (MIC: 32 mcg/ml), are common. We describe the case of a 63-year-old female patient with subarachnoid hemorrhage and VRE infection treated with Jashin-bowon-tang and Samhuang-sashim-tang for 57 days and 22 days, respectively. The therapeutic effect was assessed weekly via culture, color and viscosity of pus from a coccyx sore, and C-reactive protein (CRP). Vital signs were checked four times a day. Seventeen days after treatment, VRE was not colonized in patient and color and viscosity of pus, CRP and vital sign were improved. This case report suggests that Jashin-bowon-tang and Samhuang-sashim-tang might be an alternative option for VRE infection patients reducing the need for extended isolation periods and speeding up recovery times.

마리화나 남용환자의 역동적인 발달요인과 문제해결 (Dynamic Developmental Factors and their Problem Solving of Patients that Abuse Marihuana)

  • 원정숙
    • 대한간호학회지
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    • 제4권3호
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    • pp.105-116
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    • 1974
  • This study was made on patients who were Hospitalized due to sickness caused by the abuse of marihuana at the Psychiatric Section of a hospital during the period from Feb. to Oct., 1974. The following conclusion was obtained by reviewing the literature with respect to the nursing, and problem solving of those patients. 1. It appears that marihuana is a comparatively mild intoxicant in ordinary preparation without causing physical dependence or tolerance. 2. According to the status of men who are marihuana smokers, approximately 20% of them were college students, those preparing to retake college entrance examinations, non-employed and pharmacists. The men belong mostly to the middle foreigner′s mistress of higher, income bracket, and in the case of women, most of the smokers were US. servicemen entertainers. 3. Dynamic developmental factors: Case 1. : The patient had a characteristic, hysterical and emotionally unitable character, and was of low intelligence, In addition, to this already existing problem, the added uses of marihuana caused a mental illness to develope. Case 2 : The character, was reserved and introspective, her creative power and sentiment was fading and his ability of self-control was weakened. She used the smoking of marihuana to get rid of her own feeling of inferiority complex and tensions coming from interpersonal relationships. Case 3 : The patient was unconditionally resistive to the authoritativeness of superiors and irresponsible in his relationship with women, in his attitude concerning sex in general. He smoked marihuana because he felt become peace-loving and get enchanted experience through smoking it. 4. The points of issue appearing from the above case; (1) Movement of anti-social feelings against the "established system" by the youngsters. (2) Family problem. (3) Shamelessness, loss of motivation, disorderly attitude toward the sex, (4) Worries concerning the future. (5) Lack of knowledge concerning smoking of cigarette and marihuana. Chronic use of marihuana made, those youngman who had originally been ambitions to achieve something in life, lazy, inefficient, unable to make long-term plans, are such weak mined persons that they did not try to overcome problems when encountered. This will pose a great and important question in the mental health of the society, 5. Treatment and Problem sieving According to the literature, we will have to place importance upon hospitalized treatment The phases of treatment were divided into five parts. (1) Prehospital phase (2) Withdrawal Phase (3) Rehabilitation phase (4) Transitional phase (5) After-care phase The experiments have proved that there was much progress in the recovery of patients through environment therapy, supportive therapy and group psychotherapy. This was the above mentioned 5 phases of treating process in accordance with the weekly schedule of the hospital. It was thought that the patients would require prolonged after care management even after they were released from the hospital and that they will also require periodic visit, to the hospital and doctor′s interview with their family. In conclusion, the question of the young generation and marihuana smoking is becoming a great social problem in which their resistances to the "established system" and society is growing in the from of antiestablishment movements. In our country, the smoking of marihuana is gradually developing, therefore, I think, that it would be a very fortunate thing for us, if this report could be helpful for the motivation of further study on the questions of the young generation and its problems.

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