• Biomedical Science Letters
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• v.6 no.2
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• pp.119-129
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• 2000

The skin is an organ that has many important roles, including protection against infection, regulation of temperature and fluid loss, and sensory function. Injury to the skin, wound repair normally involves: (1) balanced activity of inflammation, (2) the re-epithelial phase and (3) the matrix formation of remodeling phase. Thus, skin wound healing is a finely controlled biological process involving a series of complex cellular interactions. Laser therapy is being implemented with increasing frequency in medicine. Low intensity laser is one that is capable of producing an energy density so low that any biologic alterations are the result of direct irradiation effect, not thermal events. This study was designed to evaluate the efficacy of low intensity laser therapy on skin wound healing in rabbits. A total of 10 male rabbits (New Zealand White Rabbit), age 8 weeks were used. Skin wound were surgically created dorso-lateral on the flank of 10 rabbits (2$\times$2 cm/damage areas). The experimental animals were treated with 5Hz (830 nm wave length) low-intensity laser (MILTA-01 Model) daily for 10 min (1.6 J/$cm^2$) for 12 days. Control animals were sham treated with the laser head. Laser irradiation animals showed a complete remodeling of the epithelial layer, a positive repair of connective tissues, and enhanced the wound closure rate over time as compared to the control animals. Especially, laser irradiation groups improved fibroblast activity, cellular content, granulation tissue formation, and collagen deposition which is resulted in improving the tensile strength of the wound. These findings suggest that laser photostimulation could accelerate healing of open wound in rabbits, and may be benefit in the treatment of open wound, including decubitis ulcers.

• Progress in Medical Physics
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• v.18 no.2
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• pp.73-80
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• 2007

Fruitful findings have been produced from five out of sixty cells which were obtained from each 63 individual Aplisia caught at the Jeju coast. Spiking patterns of three out of five cells, such as relaxation oscillator, bursting within a short time of the inter-burst interval, chaotic bursting, period doubling sequences, bursting with long trains of action potentials separated by short silent periods, regular repeated beating or elliptic bursting, and silent states had been changed in order as the temperature was lowered to $10^{\circ}C\;from\;32^{\circ}C$. In the intervals of every about 40 minutes repeated ups and downs of temperature produced similar firing patterns at the allowable temperature ranges. The other two cells showed difference from these. The amplitudes of the action potentials of the two cells will not be highly decreased in 24 hours. Average spike frequencies, the inter-burst interval, peak to peak spike amplitude of action potentials, minimum potential values are compared and analyzed by using the computer programme. The spike frequencies according to temperature show the distribution of bell type, with maximal spike frequencies at intermediate temperatures and minimal ones at either end. The most common pattern consist of high spike frequency during failing and low one during rising temperatures.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.7A
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• pp.748-755
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• 2004

In this paper, the hybrid SC/MRC technique was applied to the MC/DS-CDMA system in the Nakagami-m multi-path fading environment. The applied scheme was compared with other cases when the MRC technique was applied and then performances were analyzed. The result of analysis showed that the performance of the applied system, whose number of branches (L) for the input diversity of each carrier wave was 3 and かme selected number of branches ( Lc) was 2, was better than that of the MRC technique when the Lc of the MRC technique was 2. The performance of the applied system was lower than that of the MRC technique, then the Lc of the MRC technique was 3. However, as the fading index was lowered, which means the telecommunication environment deteriorated, the performance of the hybrid SC/MRC-(2/3) diversity technique when Lc of MRC technique was 3, was almost the same as that of the MRC technique. The hybrid SC/MRC-(2/3) diversity technique shows a similar performance to that of the MRC technique, when the Lc of the MRC technique was 4. Therefore, it was confirmed that the MC/DS-CDMA system could reduce complexity and achieve similar performance to that of the MRC by applying the hybrid SC/MRC technique, which utilized the advantages of the SC technique and high performance of the MRC scheme, rather than the MRC diversity technique that requires bit synchronization, frequency of fading, and phase synchronization for every diversity branch.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.43 no.6
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• pp.507-515
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• 2015

This paper proposes a filtering method for effective state vector estimation of highly maneuvering target. It is needed to hit the point called 'sweet spot' to increase the kill probability in missile interception. In paper, a filtering method estimates the length of a moving target tracked by a frequency modulated continuous wave (FMCW) radar. High resolution range profiles (HRRPs) is generated from the radar echo signal and then it's integrated into proposed filtering method. To simulate the radar measurement which is close to real, the study on the properties of scattering point of the missile-like target has been conducted with ISAR image for different angle. Also, it is hard to track the target efficiently with existing Kalman filters which has fixed measurement noise covariance matrix R. Therefore the proposed method continuously updates the covariance matrix R with sensor measurements and tracks the target. Numerical simulations on the proposed method shows reliable results under reasonable assumptions on the missile interception scenario.

• Journal of Biomedical Engineering Research
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• v.25 no.2
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• pp.151-156
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• 2004

The purpose of this study was to develop EMG triggered FES system for restoration of upper extremity function in chronic hemiplegic patients and to identify the optimal location of electrode application for the EMG triggered FES system which produces effective muscle contraction and detects EMG activity for extension in the wrist and finger joints. The stimulus system was composed of EMG measuring component, constant current component and the program for muscle contraction by EMG triggered FES and passive FES. Parameter of electrical stimulation was 35 ㎐ in frequency, 150 ${\mu}\textrm{s}$ in pulse width and symmetric bi-phasic wave. In 15 hemiplegic patients, EMG triggered FES was applied to the proximal half of forearm which was divided into 12 areas. The most sensitive area for measuring EMG activities during extension of the wrist and fingers was area 4, 5 and the optimal location of electrical stimulation for producing extension of the wrist and fingers was area 4, 5, 7, 8. These results suggest that the area 4 and 5 was considered as the most optimal location of electrode application for measuring EMG activities as well as producing extension of the wrist and fingers by EMG triggered FES system.

• Journal of Oriental Neuropsychiatry
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• v.21 no.3
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• pp.45-64
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• 2010

Objectives : The purpose of this study was to examine the effects of auricular acupuncture at the Shinmun on patients with dementia by using power spectrum analysis. Electroencephalogram(EEG) power spectrum show site-specific and state-related differences in various frequency bands. Methods : Study was carried out in 38 subjects.(31 patients with dementia and 7 normal people, 27 females and 11 males ; mean age=75.9 years old). To know the effect of auricular acupuncture at the Shinmun in patients with dementia, we measured electroencephalogram(EEG) of normal people and patients with dementia about 'before', 'after' and 'after 15 minutes' giving auricular acupuncture at the Shinmun, and compared the brain wave($\alpha$, $\beta$, $\delta$, $\theta$) of EEG 30 channels. Results : In the case of patients with dementia, in the power values of $\alpha$(alpha) band at F4, FP2, FCZ, F8, FC4 channels (p<0.05) during the Shinmun-auricular acupuncture treatment increased significantly. In $\beta$(beta) band, the power values at T8 channel(p<0.05) during the Shinmun-auricular acupuncture treatment increased significantly. In $\delta$(delta) band, the power values at F7, FP1, FZ, FP2, FCZ, C4, FC4, CP4, T8, P7, P3, O1, OZ, O2, P4, P8 channels(p<0.05) during the Shinmun-auricular acupuncture treatment decreased significantly. In $\Theta$(theta) band, the power values at O1, OZ, O2channel(p<0.05) during the Shinmun-auricular acupuncture treatment decreased significantly. Conclusions : Through these results, we concluded that auricular acupuncture at the Shinmun on patients with dementia could have effect the functional mechanism of the cerebral cortex.

• The Korean Journal of Physiology
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• v.28 no.1
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• pp.37-50
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• 1994

Synthetic potassium channel openers (KCOs) are agents capable of opening K-channels in excitable cells. These agents are known to have their maximal potency in the smooth muscle tissue, especially in the vascular smooth muscle. Much attention has been focused on the type of K-channel that is responsible for mediating the effects of KCOs. As the KCO-induced changes are antagonized by glibenclamide, an $K_{ATP}$ (ATP-sensitive K-channel) blocker in the pancreatic ${\beta}-cell,\;K_{ATP}$ was suggested to be the channel responsible. However, there also are many results in favor of other types of K-channel $$(maxi-K,\;small\;conductance\;K_{Ca,}\; SK_{ATP}) mediating the effects of KCOs. Effects of lemakalim, (-)enantiomer of cromakalim (BRL 34915), on the spontaneous contractions and slow waves, were investigated in the antral circular muscle of the guinea-pig stomach. Membrane currents and the effects on membrane currents and single channel activities were also measured in single smooth muscle cells and excised membrane patches by using the patch clamp method. Lemakalim induced hyperpolarization and inhibited spontaneous contractions in a dose-dependent manner. These effects were blocked by glibenclamide and low concentrations of tetraethyl ammonium (< mM). Glibenclamide blocked the effect of lemakalim on the membrane potential and slow waves. The mechanoinhibitory effect of lemakalim was blocked by pretreatment with glibenclamide. In a whole ceIl patch clamp condition, lemakalim largely increased outward K currents. These outward K currents were blocked by TEA, glibenclamide and a high concentration of intracelIular EGTA (10 mM). Volatage-gated Ca currents were not affected by lemakalim. In inside-out patch clamp experiments, lemakalim increased the opening frequency of the large conductance $Ca^{2+}-activated$ K channels $(BK_{Ca},\;Maxi-K).$ From these results, it is suggested that lemakalim induces hyperpolarization by opening K-channels which are sensitive to internal Ca and such a hyperpolarization leads to the inhibition of the spontaneous contraction.

• Smart Media Journal
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• v.9 no.2
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• pp.16-21
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• 2020

Recently, mobile traffic is increasing exponentially as major traffic is transferred to IoT and visual media data in the dissemination of mobile communication terminals and contents use. In order to overcome the limitations of the existing LTE system, 5G mobile communication technology (5G) is a technology that meets 1000 times data traffic capacity, 4G LTE system acceptance, low latency, high energy efficiency, and high cost compared to 4G LTE system. The path loss due to the use of the frequency domain is very high, so it may be difficult to provide a service compared to the existing 4G LTE system. To overcome these shortcomings, various techniques are under study. In this paper, small cell technology is introduced to improve the system performance of 5G mobile communication systems. The performance is analyzed by comparing the results of small cell technology application, macro communication and small cell communication, and the results of the proposed algorithm application for power control. The analysis results show that the use of small cell technology in the 5th generation mobile communication system can significantly reduce the shadow area and reduce the millimeter wave path loss problem.

• Bulletin of the Society of Naval Architects of Korea
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• v.26 no.1
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• pp.46-62
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• 1989

This paper presents the results of full-scale structural measurements of 4,800 unit pure car carriers "HYUNDAI NO.103" and "HYUNDAI NO.105" on one voyage respectively for each ship, especially in order to investigate the local strength of partial bulkhead above free-board deck. With the measured data, the short-term frequency analyses have been performed. The results show that the wave-induced stresses follow, on the whole, well the Rayleigh distribution. In addition, it has been found from the measured data that transverse local stresses at bulkhead section have a very close relation with the acceleration in athwartship direction. Finally, the long-term analysis has been attempted by using the following two statistical distributions mainly in order to estimate the maximum stress amplitude at the corners of partial bulkhead. 1) Exponential distribution of cycles of stress amplitude 2) Double exponential distribution of extreme values of stress amplitude for each short-term analysis The results of these two cases show a good agreement with each other. For example, the estimated maximum stress amplitude for 10 years at port-side corner of Fr. 132 partial bulkhead is $2125kg/cm^2$ for the first case and $2170kg/cm^2$ for the second case just based on the measured data.

• Korean Journal of Optics and Photonics
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• v.31 no.3
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• pp.142-147
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• 2020

In this paper, we report highly efficient second harmonic generation of continuous-wave Yb fiber lasers incorporating a periodically poled LiTaO₃ device (MgO:PPSLT) as a frequency converter. The seed laser output from a Yb fiber master oscillator using a Fabry-Perot feedback cavity was amplified in a Yb fiber amplifier stage, yielding 28.5 W of linearly polarized output at 1064 nm in a beam with beam quality, M², of ~1.07. Second harmonic generation was achieved by passing the laser beam through MgO:PPSLT. Under optimized conditions, we obtained 11.1 W of green laser output at 532 nm for an incident signal power of 25.0 W at 1064 nm, corresponding to a conversion efficiency of 44.4%. The detailed investigation to find the optimized operating conditions and prospects for further improvement are discussed.