• Phonetics and Speech Sciences
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• v.1 no.4
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• pp.203-207
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• 2009

Electrically evoked compound action potentials (ECAP) have originated from the distal end of the auditory nerve. ECAP are characterized as the difference between the clearly large trough (N) and the following positive peak (P). N-wave occurs around $200-400\;{\mu}s$ after stimulus onset and P-wave at around $400-800\;{\mu}s$. Contrary to expectations, positive peaked ECAP (pp-ECAP) was dominated by a relatively large-amplitude positive following negative peak. pp-ECAP can be recorded from the sites on or near the surgically exposed nerve trunk in animal models and/or in cases of monophasic stimulation. This study will provide the causes of the appearance of pp-ECAP in cases of cochlear implant recipients using imaging studies and medical records and statistically analysis between N-P and P-N on the amplitude input-output function (amp-I/O) for the prediction of the possibilities of clinical tools. Thirteen children participated in the study and received a Cochlear CI-24RE (CA). ECAP was recorded using auto-NRT (Cochlear Ltd., Australia) at four to five weeks post surgery. pp-ECAP was measured from 36 electrodes and typical ECAP from 220 electrodes. There was no abnormality in the imaging study and operation finding in patients with typical ECAP. pp-ECAP was found at the inner ear anormaly and ossification in imaging study and gel-state inner ear fluid was observed in the operation finding. The amplitude of pp-ECAP increased depending on current intensities, but amp-I/O increase more gradually than in the case of typical ECAP (p=0.003). pp-ECAP is antidromic potential which can record from the inner ear anormaly and ossified cochlear. Amp-I/O also depends on current intensity as well typical ECAP. These results provide a useful tool for audiological evaluation for the spiral ganglion cell status to the value of pp-ECAP.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.6
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• pp.2554-2560
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• 2011

This study is focused on the effects of one's blood type on emotional character and anti-stress by comparing each individual's brain wave. Observed records are from those kids who volunteered for KRIJUS(Korea Research Institute of Jungshin Science)'s brain wave measurement from September 2006 to December 2009. The whole 4636 adult(20-59 age) group consists of 3221 female and 1415 male. Blood types are as follows; A>B>O>AB dominately ordered. The result shown no relations between the blood types of adult and their emotional character. But meaningful difference had been revealed between the blood type and stress resistancy; type O rated higher scores in awarness and stress resistancy then other types, which shows that type O has more ability to redudce its stress. This study revealed meaningful relation between blood types and emotional character among several categoties, while suggesting follow-up researches figuring out more detailed explanations for its effect and genetic role.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.6
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• pp.2072-2077
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• 2010

This study is focused on the effects of elder's blood type on determining awareness and emotional character of the elderly, by comparing each individual's brain wave. Observed records are from thoes elder's who volunteered for KRIJUS( Korea Research Institute of Jungshin Science)'s brain wave measurement from September 2008 to June 2009. The whole 762 elder group consists of 311 female and 451 male. Blood types are A>B>O>AB dominately ordered. The result shown no relations between the blood types and their emotional character among elderly female, while elderly men shown meaningful difference; type B and O had higher rate on negative aspects. When it comes to awareness categories, both emotional(p=.001) and active(right)(p=.040) index shown meaningful differences. Type A had highest rate on emotional index and AB had it on active index. This study revealed meaningful relation between blood types and emotional character among several categories, while suggesting follow-up researches figuring out more detailed explanations for its effect and genetic role.

• Journal of the Korean Society of Hazard Mitigation
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• v.8 no.4
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• pp.145-152
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• 2008

The initial wave lengths of tsunamis can be several tens to hundreds kilometers. Thus, the importance of the frequency dispersive effects in proportion to variation of the wave length, and should be properly considered in numerical simulation of tsunami propagation for a better accuracy. Recently, a practical dispersion-correction scheme has been developed by adding dispersion-correction terms(Cho et al., 2007). The new model employing the numerical technique has been verified by comparing numerical results with available analytic solutions, however, the new model has not yet been applied on a real topography. In this study, the new model is applied on a real topography and its applicability is examined. To study the applicability of the new model, two historical tsunami events are simulated for Sokcho, Mukho and Pohang harbors, with the tide gage records. Numerical results, the arrival time and the maximum water level at the tidal stations, are compared with observed data at each harbor.

• Journal of the Korean Institute of Intelligent Systems
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• v.23 no.4
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• pp.292-297
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• 2013

In this paper, unusual waveform detection algorithm based on Refractory Period in arrhythmia ECG signal is proposed. Most of arrhythmia ECG signals consist of unusual waveforms with average 10% rate. Thus tremendous benefit can be obtained in terms of time and cost by providing unusual waveform samples reduced more than 90% to medical staffs who have to monitor and analyze for a long time. The proposed algorithm detects the R-peak using the features of R wave and variable refractory period. For the detected R-peak, unusual waveforms are found using means and standard deviation of electric potential and kurtosis of the R-peaks which are not included in unusual waveform. The proposed algorithm was applied to all records of the MIT-BIH arrhythmia database and showed more than average 90% of compression ratio.

• The Korean Journal of Physiology and Pharmacology
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• v.17 no.3
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• pp.229-235
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• 2013

Among several animal models of retinitis pigmentosa (RP), the more recently developed rd10 mouse with later onset and slower rate of retinal degeneration than rd1 mouse is a more suitable model for testing therapeutic modalities. We therefore investigated the time course of retinal degeneration in rd10 mice before adopting this model in our interventional studies. Electroretinogram (ERG) recordings were carried out in postnatal weeks (PW) 3~5 rd10 (n=23) and wild-type (wt) mice (n=26). We compared the amplitude and implicit time of the b-wave of ERG records from wt and rd10 mice. Our results showed that b-wave amplitudes in rd10 mice were significantly lower and the implicit time of b-waves in rd10 mice were also significantly slower than that in wt mice ($20{\sim}160{\mu}V$ vs. $350{\sim}480{\mu}V$; 55~75 ms vs. 100~150 ms: p<0.001) through PW3 to PW5. The most drastic changes in ERG amplitudes and latencies were observed during PW3 to PW4. In multichannel recording of rd10 retina in PW2 to PW4.5, we found no significant difference in mean spike frequency, but the frequency of power spectral peak of local field potential at PW3 and PW3.5 is significantly different among other age groups (p<0.05). Histologic examination of rd10 retinae showed significant decrease in thickness of the outer nuclear layer at PW3. TUNEL positive cells were most frequently observed at PW3. From these data, we confirm that in the rd10 mouse, the most precipitous retinal degeneration occurs between PW3~PW4 and that photoreceptor degeneration is complete by PW5.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.9 no.6
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• pp.1818-1824
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• 2008

This study is focused on the effects of one's blood type on emotional character of children, by comparing each individual's brain wave. Observed records are from those kids who volunteered for KRIJUS(Korea Research Institute of Jungshin Science)'s brain wave measurement from September 2005 to December 2007. The whole 3018 kids(4-7) group consists of 1322 female and 1696 male. Blood types are A>B>O>AB dominately ordered. The relations between depressive attitude and blood type of an infant couldn't be found among female. However, male type B had the most numbers of activeness character while type O shown largest rate of depressed condition. Also, the result amongst infant had shown male type B had the most active-positive rate while type AB took large for depressed-negative. The result had shown no relative connection for activity inclination. Third, among the kids type O had highest awareness rate while type A had lowest. This study revealed meaningful relation between blood types and emotional character among several categories, while suggesting follow-up researches figuring out more detailed explanations for its effect and genetic role.

• Economic and Environmental Geology
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• v.18 no.2
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• pp.151-157
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• 1985

Events detected by the KIER microearthquake network operated in the Southern Part of Korea for 265 days in 1982~1984 were reviewed, and some of them were identified to be a dynamite explosion from several construction sites. The purpose of the present work is to determine the crustal structure of the Southern Korea using the time-destance data obtained from such explosion seismic records. The time·distance data can be well explained by a crustal model composed of four horizontal layers of which thickness, p and s-wave velocity ($V_p$ and $V_s$) are characterized as follows. 1st layer (surface) ; 0~2km, $V_p=5.5km/sec$, $V_s=3.3km/sec$ 2nd layer (upper crust) ; 2~15km, $V_p=6.0km/sec$, $V_s=3.5km/sec$ 3rd layer (lower crust) ; 15~29km, $V_p=6.6km/sec$, $V_s=3.7km/sec$ 4th layer (upper mantle) ; 29km~ , $V_p=7.7km/sec$, $V_s=4.3km/sec$ The relatively shallow crust·mantle boundary and low $P_n$ velocity compared with the mean values for stable intraplate region are noteworthy. Supposedely, it is responsible for the high heat flow in the South-eastern Korea or an anomalous subterranean mantle. The mean $V_p/V_s$ ratio calculated from the relation between p-wave arrival and s-p arrival times appears to be 1.735 which is nearly equivalent to the elastic medium of ${\lambda}={\mu}$. However, the ratio tends to be slightly larger with the depth. The ratio is rather high compared with that of the adjacent Japanese Island, and the fact suggests that the underlying crust and upper mantle in this region are more ductile and hence the earthquake occurrences are apt to be interrupted. As an alternative curstal model, a seismic velocity structure in which velocities are successively increased with the depth is also proposed by the inversion of the time·distance data. With the velocity profile, it is possible to calculate a travel time table which is appropriate to determine the earthquake parameters for the local events.

• Journal of Preventive Medicine and Public Health
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• v.56 no.6
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• pp.542-551
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• 2023

Objectives: Prospective studies on vaccination status and mortality related to coronavirus disease 2019 (COVID-19) in low-resource settings are still limited. We assessed the association between vaccination status (full, partial, or none) and in-hospital mortality among COVID-19 patients at most hospitals in Jakarta, Indonesia during the Delta predomination wave. Methods: We conducted a retrospective cohort study among hospitalized COVID-19 patients who met the study criteria (>18 years old and admitted for inpatient treatment because of laboratory-confirmed severe acute respiratory syndrome coronavirus 2 infection). We linked individual-level data in the hospital admission database with vaccination records. Several socio-demographic and clinical characteristics were also analyzed. A Cox proportional hazards regression model was used to explore the association between vaccination status and in-hospital mortality in this patient group. Results: In total, 40 827 patients were included in this study. Of these, 70% were unvaccinated (n=28 543) and 19.3% (n=7882) died during hospitalization. The mean age of the patients was 49 years (range, 35-59), 53.2% were female, 22.0% had hypertension, and 14.2% were treated in the intensive care unit, and the median hospital length of stay across the group was 9 days. Our study showed that the risk of in-hospital mortality among fully and partially vaccinated patients was lower than among unvaccinated adults (adjusted hazard ratio [aHR], 0.43; 95% confidence interval [CI], 0.40 to 0.47 and aHR, 0.70; 95% CI, 0.64 to 0.77, respectively). Conclusions: Vaccinated patients had fewer severe outcomes among hospitalized adults during the Delta wave in Jakarta. These features should be carefully considered by healthcare professionals in treating adults within this patient group.

• Pediatric Infection and Vaccine
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• v.29 no.3
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• pp.131-140
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• 2022

Purpose: Since the coronavirus disease 2019 (COVID-19) pandemic began, new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have emerged, and distinct epidemic waves of COVID-19 have occurred for an extended period. This study aimed to analyze the clinical and epidemiological characteristics of children with COVID-19 from the third wave to the middle of the fourth epidemic wave in Korea. Methods: We retrospectively reviewed the medical records of hospitalized patients aged ≤18 years with laboratory-confirmed COVID-19. The study periods were divided into the third wave (from November 13, 2020 to July 6, 2021) and the fourth wave (from July 7 to October 31, 2021). Results: Ninety-three patients were included in the analysis (33 in the third and 60 in the fourth waves). Compared with the third wave, the median age of patients was significantly older during the fourth wave (6.7 vs. 2.8 years, P=0.014). Household contacts was reported in 60.2% of total patients, similar in both periods (69.7 vs. 55.0%, P=0.190). Eighty-one (87.1%) had symptomatic SARS-CoV-2 infection. Among these, 10 (12.3%) had no respiratory symptoms. Anosmia or ageusia were more commonly observed in the fourth epidemic wave (10.7 vs. 34.0%, P=0.032). Most respiratory illness were upper respiratory tract infections (94.4%, 67/71), 4 had pneumonia. The median cycle threshold values (detection threshold, 40) for RNA-dependent RNA polymerase (RdRp) and envelope (E) genes of SARS-CoV-2 were 21.3 and 19.3, respectively. There was no significant difference in viral load during 2 epidemic waves. Conclusions: There were different characteristics during the two epidemic waves of COVID-19.