• Title/Summary/Keyword: Water Shock

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A Simple Behavioral Paradigm to Measure Impulsive Behavior in an Animal Model of Attention Deficit Hyperactivity Disorder (ADHD) of the Spontaneously Hypertensive Rats

  • Kim, Pitna;Choi, In-Ha;Dela Pena, Ike Campomayor;Kim, Hee-Jin;Kwon, Kyung-Ja;Park, Jin-Hee;Han, Seol-Heui;Ryu, Jong-Hoon;Cheong, Jae-Hoon;Shin, Chan-Young
    • Biomolecules & Therapeutics
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    • v.20 no.1
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    • pp.125-131
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    • 2012
  • Impulsiveness is an important component of many psychiatric disorders including Attention-deficit/hyperactivity disorder (ADHD). Although the neurobiological basis of ADHD is unresolved, behavioral tests in animal models have become indispensable tools for improving our understanding of this disorder. In the punishment/extinction paradigm, impulsivity is shown by subjects that persevere with responding despite punishment or unrewarded responses. Exploiting this principle, we developed a new behavioral test that would evaluate impulsivity in the most validated animal model of ADHD of the Spontaneously Hypertensive rat (SHR) as compared with the normotensive "control" strain, the Wistar Kyoto rat (WKY). In this paradigm we call the Electro-Foot Shock aversive water Drinking test (EFSDT), water-deprived rats should pass over an electrified quadrant of the EFSDT apparatus to drink water. We reasoned that impulsive animals show increased frequency to drink water even with the presentation of an aversive consequence (electro-shock). Through this assay, we showed that the SHR was more impulsive than the WKY as it demonstrated more "drinking attempts" and drinking frequency. Methylphenidate, the most widely used ADHD medication, significantly reduced drinking frequency of both SHR and WKY in the EFSDT. Thus, the present assay may be considered as another behavioral tool to measure impulsivity in animal disease models, especially in the context of ADHD.

Microbiological Quality Control of Cooked Rice by Aseptic Process Using Heat Shock Treatment (열쇼크방식 살균에 의한 무균 취반의 미생물학적 품질관리)

  • 홍정화;허성호;신명호
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.27 no.6
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    • pp.1094-1099
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    • 1998
  • Newly introduced aseptic process for cooked rice was optimized by evaluating the process parameters. The optimal conditions were as follows: ratio of washing water to rice, 3:1 by weight; steeping at 20oC for 20min; heat shock at 140oC for 7sec with 8 repetitions; addition of 0.2% glucono lactone solution; cooking at 103oC for 30min. The final products were incubated at 37oC and 50oC for 8 weeks and no spoilage was occurred at both temperatures. Furthermore, any significant losses of sensory and physicochemical qualities were not observed.

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Computations of Compressible Two-phase Flow using Accurate and Efficient Numerical Schemes

  • Kim, Chong-Am
    • 한국전산유체공학회:학술대회논문집
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    • 2006.10a
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    • pp.13-17
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    • 2006
  • RoeM and AUSMPW+ schemes are two of the most accurate and efficient schemes which are recently developed for the analysis of single phase gas dynamics. In this paper, we developed two-phase versions of these schemes for the analysis of gas-liquid large density ratio two-phase flow. We adopt homogeneous equilibrium model (HEM) using mass fraction to describe different two phases. In the Eulerian-Eulerian framework, HEM assumes dynamic and thermal equilibrium of the two phases in the same computational mesh. From the mixture equation of state (EOS), we derived new shock-discontinuity sensing term (SDST), which is commonly used in RoeM and AUSMPW+ for the stable numerical flux calculation. The proposed two-phase versions of RoeM and AUSMPW+ schemes are applied on several air-water two-phase test problems. In spite of the large discrepancy of material properties such as density, enthalpy, and speed of sound, the numerical results show that both schemes provide very satisfactory solutions.

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Visualization of Underwater Sympathetic Detonation of High Explosives

  • Itoh, Shigeru;Hamada, Toru;Murata, Kenji;Kato, Yukio
    • Journal of Mechanical Science and Technology
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    • v.15 no.12
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    • pp.1822-1828
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    • 2001
  • The experiment for the sympathetic detonation (Sudo et al., 1951) (Fukuyama et al., 1958) in water was conducted. Composition B (RDX: 64%, TNT: 36%, Detonation velocity: 7900m/s) was used for both donor (the thickness was 50mm, and the diameter was 31mm) and receptor charges. The distance between the donor and the receptor, and the thickness (5, 7.5, 10mm) of the receptor were varied in the experiments. In order to investigate the basic characteristics of the underwater sympathetic detonation of high explosive, the sympathetic detonation phenomena were visualized by a high-speed camera (HADLAND PHOTONICS, IMACON790) in forms of streak and framing photographs. The 200ns/mm streak velocity was 2㎲. Manganin gauges (KYOWA Electronic INSTRUMENTS CO. SKF-21725) were used for the pressure measurements. The gauges were set under the receptor. The pressures during the complete and incomplete explosions were measured.

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Spitzer IRS mapping of L1251B

  • Lee, Jeong-Eun
    • The Bulletin of The Korean Astronomical Society
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    • v.35 no.1
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    • pp.58.2-58.2
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    • 2010
  • L1251B, which was revealed as a small group of protostars by the Spitzer Space Telescope (SST), presents a great site of studying chemical evolution in gas and ice as well as various dynamical processes associated with star formation (infall, rotation, and outflow). We have mapped L1251B with the Infrared Spectrograph (IRS) aboard the SST to study the chemical distribution in the phases of gas and ice and the dynamical feature related to shock in the region. Various atomic lines and the $H_2$ pure rotational lines, which trace different shock velocities, were detected. In addition, the distribution of the water and $CO_2$ ices hints variety of the ice desorption mechanism in L1251B.

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Influence of Input Parameters on Shock Wave Propagation in Quasi-3D Hydrodynamic Model (준3차원 동수역학 모형의 입력변수가 충격파 전파에 미치는 영향)

  • Rhee, Dong Sop;Kim, Hyung-Jun;Song, Chang Geun
    • Journal of the Korean Society of Safety
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    • v.32 no.2
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    • pp.112-116
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    • 2017
  • Present study investigated the influence of time step size, turbulent eddy viscosity, and the number of layer on rapid and unsteady propagation of dam break flow. When the time step size had a value such that it resulted in Cr of 0.89, a significant numerical oscillation was observed in the vicinity of the wave front. Higher turbulent viscosity ensured smooth and mild slope of velocity and water stage compared with the flow behavior by no viscosity. The vertical velocity at the lower layer positioned near the bottom showed lower velocity compared with other layers.

Evaluation of Reference Temperature on Pressurized Thermal Shock for Domestic Pressurized Water Reactors (국내 가압경수형 원자로에 대한 가압열충격 기준온도 평가)

  • Choi, Young Hwan;Park, Jeong Soon;Jhung, Myung Jo
    • Transactions of the Korean Society of Pressure Vessels and Piping
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    • v.6 no.2
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    • pp.42-46
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    • 2010
  • The evaluation method for the failure frequency of reactor vessel under pressurized thermal shock(PTS) is developed using probabilistic fracture mechanics. The probabilistic reactor integrity evaluation code, named R-PIE code, is developed. The validity and uncertainty of the R-PIE code is investigated. The reactor failure frequencies under PTS for Kori-1 nuclear power plant and other type of domestic nuclear power plants are evaluated. The reference PTS temperature for domestic nuclear power plants is obtained for the rule making against PTS failure.

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DC Leakage Current Properties Analysis of the LED Lamps of Road and Landscape Lighting (LED 가로등 및 경관조명의 직류 누전 특성 분석)

  • Kim, Hyang-Kon;Kim, Dong-Woo;Choi, Hyo-Sang
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.60 no.4
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    • pp.885-891
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    • 2011
  • In this paper, we studied dc leakage current properties analysis of LED lamps of road and landscape lighting when leakage current appeared in dc power line. Generally, converter of LED lighting is divides to insulated type and non-insulated type according to components. When electric leakage happened in AC power line, earth leakage breaker(ELB) senses leakage current and interrupts electric circuit. In dc power source, We need experimental verification about dc electric leakage for electricity safety. In normal wiring conditions and in the water, in case of using insulated type of converter, dc leakage current did not occur. However, in case of using non-insulated type of converter, dc leakage current occurred and passed through into the ground. We found that there is a hazard of electric shock by dc leakage current. We expect that the results of these studies would be helpful for electrical safety of LED lamps for road and landscape lighting.

Influence of head structure on hydrodynamic characteristics of transonic motion projectiles

  • Wang, Rui;Yao, Zhong;Li, Daqin;Xu, Baocheng;Wang, Jiawen;Qi, Xiaobin
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.12 no.1
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    • pp.479-490
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    • 2020
  • The hydrodynamic characteristic of transonic motion projectiles with different head diameters are investigated by numerical simulation. Compressibility effect in liquid-phase water are modeled using the Tait state equation. The result shows that with increasing of velocity the compression waves transfer to shock waves, which cause the significant increasing of pressure and decreasing the dimensions of supercavities. While the increasing of head diameter, the thickness, the vapor volume fraction and the drag coefficient of supercavities are all enhanced, which is conducive to the stability of transonic-speed projectiles. The cavity dynamics of the different head projectiles are compared, and the results shows when Mach number is in high region, the truncated cone head projectile is enveloped by a cavity which results in less drag and better stability.

Effects of Laser Source Geometry on Laser Shock Peening Residual Stress (레이저 광원 형상이 레이저 충격 피닝 잔류응력에 미치는 영향)

  • Kim, Ju-Hee;Kim, Yun-Jae;Kim, Joung-Soo
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.36 no.6
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    • pp.609-615
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    • 2012
  • In LSP (laser shock peening) treatment, the laser source geometries when the laser beam strikes the metal target area are diverse. The laser spot geometry affects the residual stress field beneath the treated surface of the metallic materials, which determines the characteristics of the pressure pulse. In this paper, detailed finite-element (FE) simulations on laser shock peening have been conducted in order to predict the magnitude and of the residual stresses and the depth affected in Inconel alloy 600 steel. The residual stress results are compared for circular, rectangular, and elliptical laser spot geometries. It is found that a circular spot can produce the maximum compressive residual stresses near the surface but generates tensile residual stresses at the center of the laser spot. In the depth direction, an elliptical laser spot produces the maximum compressive residual stresses. Circular and elliptical spots plastically affect the alloy to higher depths than a rectangular spot.