• Proceedings of the Korea Contents Association Conference
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• 2009.05a
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• pp.759-764
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• 2009

With its rapid growth, the digital contents-related industry is drawing attention as an industry generating a high value added. Specifically, the 3D morphing technology often used in the appearance or movement of each object comprising contents makes it possible to compose various contents by inferring the appearance and movement of the object. For a realistic swimming appearance of fish by using fish that swim in the water, this paper proposes a technique that applies the same speed concept as a physical pendulum to a swimming cycle and applies a frame morphing technique that is able to express the growth process from fry to adult fish. This article is capable of realistically reviving the fish growth process, and can through magnified applying can be applied to in 3D fishes encyclopedias or virtual underwater expressions etc. in the viewpoint which is oceanography.

• Conservation Science in Museum
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• v.2
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• pp.35-40
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• 2000

Conservation Science Lab. of the National Museum of Korea recovered Bamboo-plated inkstone case which is used for keeping inkstick, inkstone and inkstone water container by using traditional lacquering and wooden art technology. Texture and construction method of wood, ingredients for lacquering and the method, and the design were analyzed in order to restore the original manufacturing method. Especially, perfect restoration of partially damaged lacquer surface is the most important aspect in restoring Bamboo plated inkstone case, therefore focus was put on investigation of surface lacquering. First, lacquering surface sample was taken off from the object and processed into flake and observed with transmission microscope in order to investigate lacquering method and the pigment in the lacquering surface was analyzed with XRD and SEM-EDS. The result showed that the object was decorated with thin-layered bamboo in the surface which is made of Royal paulownio. and lacquered several times with the mixture of Hematite(Fe₂O₃) and Cinnabar(HgS) in the remaining part.

• Toxicological Research
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• v.31 no.1
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• pp.17-23
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• 2015

Excessive manganese (Mn) in the brain promotes a variety of abnormal behaviors, including memory deficits, decreased motor skills and psychotic behavior resembling Parkinson's disease. Hereditary hemochromatosis (HH) is a prevalent genetic iron overload disorder worldwide. Dysfunction in HFE gene is the major cause of HH. Our previous study has demonstrated that olfactory Mn uptake is altered by HFE deficiency, suggesting that loss of HFE function could alter manganese-associated neurotoxicity. To test this hypothesis, Hfe-knockout ($Hfe^{-/-}$) and wild-type ($Hfe^{+/+}$) mice were intranasally-instilled with manganese chloride ($MnCl_2$ 5 mg/kg) or water daily for 3 weeks and examined for memory function. Olfactory Mn diminished both short-term recognition and spatial memory in $Hfe^{+/+}$ mice, as examined by novel object recognition task and Barnes maze test, respectively. Interestingly, $Hfe^{-/-}$ mice did not show impaired recognition memory caused by Mn exposure, suggesting a potential protective effect of Hfe deficiency against Mn-induced memory deficits. Since many of the neurotoxic effects of manganese are thought to result from increased oxidative stress, we quantified activities of anti-oxidant enzymes in the prefrontal cortex (PFC). Mn instillation decreased superoxide dismutase 1 (SOD1) activity in $Hfe^{+/+}$ mice, but not in $Hfe^{-/-}$ mice. In addition, Hfe deficiency up-regulated SOD1 and glutathione peroxidase activities. These results suggest a beneficial role of Hfe deficiency in attenuating Mn-induced oxidative stress in the PFC. Furthermore, Mn exposure reduced nicotinic acetylcholine receptor levels in the PFC, indicating that blunted acetylcholine signaling could contribute to impaired memory associated with intranasal manganese. Together, our model suggests that disrupted cholinergic system in the brain is involved in airborne Mn-induced memory deficits and loss of HFE function could in part prevent memory loss via a potential up-regulation of anti-oxidant enzymes in the PFC.

• Special Issue of the Society of Naval Architects of Korea
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• 2011.09a
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• pp.32-35
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• 2011

Template has been widely used for hull forming process in most of shipyards. It is used to estimate the curvature of deformed shape in comparison with design shape. SHI (Samsung Heavy Industry) had used AutoKon system for ship manufacturing design in the past. The AutoKon used the global coordinate system of ship (frame, water line and so on) to create template data. It brought the mismatched angles between templates and a curved shell plate. The mismatched angle is measured by forming worker to place template on shell forming stage. However, the mismatched angle is difficult to place template with exactly required angle because the shell plates have various curvature and size. It causes incorrect shape of formed shell plates. The attached angle of template should be 90 degree to place template easily on forming shell plates. Currently, SHI has been applied GSCAD for ship manufacturing design process which is 3D solid modeling system. The GSCAD is the rule-based system which can automate 3D modeling and control the manufacturing data by rule. The rule can easily provide methods to create and automate template object with regular attached angle in comparison with AutoKon system. Therefore, SHI developed new template rule which it can automatically create template object with regular attached angle in GSCAD.

• The Journal of the Korea Contents Association
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• v.7 no.3
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• pp.68-78
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• 2007

In a virtual aquarium, the behavior of fish objects is the most important factor in respect of visual effects. In addition to the individual behavior of fish object, the interactions between objects due to their attributes, can improve the dynamics and reality of the virtual world. In this paper, we analyze the principal habits of fish objects such as the vitality, the range of movement, the maximum depth of water they can live, and the cycle of eating. Then, we suggest a method for simulating the stable marine ecosystem with controlling the behaviors, the interaction with other species, the average span of life, and all that sort of thing based on the result of analysis. Because we can freely modify the behavior of fish object by altering the values of attributes, it can be utilized in the dynamic virtual aquarium, the 3D aquarium screen saver, and the virtual fish game, and so on.

• Journal of The Geomorphological Association of Korea
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• v.19 no.2
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• pp.69-79
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• 2012

The aim of this study is to analyze the mid-term changes of beach and dune morphology at Sohwang beach, Korea using by Total Station. Measurements executed 4 times during two year. Based on ArcInfo as point cloud obtained through precise measurement data by Total Station, alteration of beach and dune was analyzed at DEM, of which cell size is about 1m. Since these artificial constructions have influenced current systems of this region, the large-scale sand movements above mentioned have occurred around the jetty and the sea-wall. There occurred sedimentation in the north of the Jetty and erosion in the south of the Jetty, which is installed at the central part of object area. The direction of recent topographic development does not coincide with that of wind, and, rather, topographic changes occurred mainly at beaches and dunes due to the transformation of coastal water flow caused by artificial structure nearby. If precise measurement is conducted periodically, and long term monitoring is carried out by installing equipment measuring movement pattern of sediment around artificial structure, cause of topographic change around the object area could be discovered.

• Nutrition Research and Practice
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• v.16 no.2
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• pp.173-193
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• 2022

BACKGROUND/OBJECTIVES: Alzheimer's disease (AD) is one of the most representative neurodegenerative disease mainly caused by the excessive production of amyloid beta (Aβ). Several studies on the antioxidant activity and protective effects of Populus tomentiglandulosa (PT) against cerebral ischemia-induced neuronal damage have been reported. Based on this background, the present study investigated the protective effects of PT against cognitive impairment in AD. MATERIALS/METHODS: We orally administered PT (50 and 100 mg/kg/day) for 14 days in an Aβ_25-35-induced mouse model and conducted behavioral experiments to test cognitive ability. In addition, we evaluated the levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in serum and measured the production of lipid peroxide, nitric oxide (NO), and reactive oxygen species (ROS) in tissues. RESULTS: PT treatment improved the space perceptive ability in the T-maze test, object cognitive ability in the novel object recognition test, and spatial learning/long-term memory in the Morris water-maze test. Moreover, the levels of AST and ALT were not significantly different among the groups, indicating that PT did not show liver toxicity. Furthermore, administration of PT significantly inhibited the production of lipid peroxide, NO, and ROS in the brain, liver, and kidney, suggesting that PT protected against oxidative stress. CONCLUSIONS: Our study demonstrated that administration of PT improved Aβ_25-35-induced cognitive impairment by regulating oxidative stress. Therefore, we propose that PT could be used as a natural agent for AD improvement.

• Fisheries and Aquatic Sciences
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• v.26 no.6
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• pp.380-392
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• 2023

Groupers (Family Epinephelidae) are commonly caught in data-poor small-scale multi-species fisheries for sale on both export and domestic markets. This study presents data on the species composition and size/life-stage structure of Epinephelus spp. groupers caught by small-scale fishers and sold locally in the Indonesian province of South Sulawesi. Data were collected from fishing ports and local markets at 12 sites representing the three seaways around South Sulawesi (Makassar Strait, Flores Sea, Gulf of Bone). Each specimen (n = 3,398) was photographed alongside an object of known length, and total length (TL) was obtained using the Rapid Scaling on Object (RASIO). Of the 23 species identified, four (Epinephelus areolatus, Epinephelus ongus, Epinephelus quoyanus, and Epinephelus fasciatus) collectively comprised 69% of the catch, while the 13 least abundant species contributed less than 5%. The catch was dominated (67%) by the subadult life-stage, with just under 20% in the adult class. Juveniles dominated the catch of Epinephelus fuscoguttatus, a valuable export commodity. Observations of early maturity as well as the sizeable gap between length at first capture (Lc) and length at first maturity (Lm) indicate recruitment overfishing of most species, with the notable exception of Epinephelus rivulatus. The proportion of adult fish was low (≈5%-30%) for the twelve most abundant species (E. areolatus, E. ongus, Epinephelus quoyanus, E. fasciatus, Epinephelus coioides, Epinephelus faveatus, Epinephelus sexfasciatus, Epinephelus maculatus, Epinephelus bleekeri, Epinephelus corallicola, E. fuscoguttatus, Epinephelus polyphekadion). For two moderately abundant species (E. faveatus and E. malabaricus), TL < Lm for all specimens. The limited data available indicate spawning ratio is lower than reported from deep-water fisheries of E. areolatus and E. coioides. The results call for targeted research to fill knowledge gaps regarding the biology and ecology of groupers exploited mainly for domestic markets; highlight the need for species-level data to inform management policies such as minimum legal size regulations; and can contribute towards species-level status assessments.

• Journal of the Korean GEO-environmental Society
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• v.16 no.1
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• pp.29-36
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• 2015

Current domestic research is to demonstrate the effectiveness and efficiencies of flood prevention measures through one-dimensional numerical analysis and this study's object is to help water managers to make the efficient decisions by applying the two-dimensional urban run off model XP-SWMM model in the flooded area and comparing with the flood prevention measures. Statistics were analyzed, based on the data collected from Cheongju Weather Service from 1967 to 2011 for 45 years. 50 years Flood frequency simulations of water flow capacity analysis of the target area for flooded areas $539,548m^2$, inundation depth 1.0 m, was analyzed by inundation time of 48 minutes. When comparing with the constructions of bypass road and underground storage facilities to increase the water flow capacity of A1 small drainage areas as flood protection, if you install a batching target underground detention basin with a capacity of $13,500m^3$, it is expected that the flood by rainfall with frequency of 50 years will be resolved completely. In preparation for extreme weather in the future flood mitigation measures, underground storage tank installation is considered a better efficient way.

• Journal of Pharmaceutical Investigation
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• v.32 no.2
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• pp.73-80
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• 2002

Cefuroxime axetil is a cephalosporin antibiotic having a high activity against a wide spectrum of Grampositive and Gram-negative microorganisms. It is a cephalosporin antibiotic which exist as 2 diastereoisomers: diastereoisomer A and B. It shows polymorphism of three forms: a crystalline form having a melting point of about $180^{\circ}C$, a substantially amorphous form having a high melting point of about $135^{\circ}C$ and a substantially amorphous form having a low melting point of about 70^{\circ}C$. The crystalline form of cefuroxime axetil is slightly soluble in water because diastereoisomer A has lower solubility than B in water. Substantially amorphous form of which there are no difference in solubility between diastereoisomer A and B has better solubility than crystalline form, but it forms a thicker gel than crystalline form upon contact with an aqueous medium. Based on this reason, cefuroxime axetil is not readily absorbable in the gastrointestinal tract, rendering its bioavailability on oral administration very low. The object of this study was to develop an improved non-crystalline cefuroxime axetil composition having a high physicochemical stability and bioavailability. A non-crystalline cefuroxime axetil solid dispersant showing no peak on a Differential Scanning Calorimetry (DSC) scan is prepared by dissolving cefuroxime axetil and a surfactant in an organic solvent; suspending a water-insoluble inorganic carrier in the resulting solution; and spray drying the resulting suspension to remove the organic solvent, said solid dispersant having an enhanced dissolution and stability of cefuroxime axetil and being useful for the preparation of a pharmaceutical composition for oral administration. Tablet was formulated with this cefuroxime axetil solid dispersant, disintegrants and other ingredients. It disintegrated and dissolved easily and dynamically in dissolution medium, so showed a good dissolution profile.