• The Journal of Korean Medicine
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• v.39 no.4
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• pp.183-192
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• 2018

Objectives: The purpose of this study is to report effectiveness of MY1-Hwan(MYH) on wart patients. Methods: Seven wart patients who wanted to treat wart with Korean medicine took MYH 2~3 times a day for 2~4 months without external treatments. Results: Nodules or papules of wart were vanished from seven patients' lesion. Specific side effect was not shown. Conclusions: MYH was effective to treat seven wart cases. However, seven cases are not enough to figure out the various effects of MYH and the effectiveness on other kind of wart. So follow-up studies are needed based on this study.

• CELLMED
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• v.13 no.7
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• pp.26.1-26.3
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• 2023

Objective: A case report of wart patient treated with Ortho-cellular Nutritional Therapy. Methods: A 95-year-old Korean male with a large wart measuring more than 1cm in diameter, experiencing no pain but discomfort in daily life. Results: After 50 days of applying nutritional therapy, the wart completely disappeared. Conclusion: The application of nutritional therapy can soften the hardened tissue of warts and aid in the treatment process.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.22 no.2
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• pp.192-200
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• 2009

Objective : The purpose of this study is to investigate the characteristics of patients with warts. Methods : We conducted statistics study on 100 patients, who had visited to Wart Clinic, from September 2008 to February 2009. Results : The results were as follows. 1. The wart was found more often from female(64%) than from male(36%). The age distributions of patients showed highest in 21-30 years, followed by 31-40 years, and 11-20 years. 2. The distributions of duration of warts showed highest in 1-5 years, followed by 6-10 years, and over 10 years. 3. The most common warts were Verruca plana(48%), Verruca vulgaris(25%), Verruca vulgaris with Palmoplantar wart(14%), Verruca plana with Verruca vulgaris(9%). 4. The Verruca vulgaris was found mostly in the hand, whereas the Verruca plana was seen mostly in the face. 5. Laser therapy was the most common previous treatment, followed by cryotherapy, immunotherapy in order. 6. The distributions of duration of treatment showed highest in 1-4 weeks, followed by 5-8 weeks, 9-12 weeks in order. 7. After treatment, 43 cases(43%) showed complete clearance, and 29 cases(29%) showed partial clearnace. Conclusion : We analyzed the characteristics of patients with warts. Further studies would be needed to develop the better treatment on warts.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.5
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• pp.1070-1074
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• 2002

We observed and treated a 18 year old male who hae been diagnosed with plane wart. Even though he had been treated with western surgery(Laser operating), he still com planed of recurrent plane wart, suffusion, itching. We treated him with ambulatory treatment and herb medication preventing from high fat diet. Treated for 80 days, his symptoms were almost disappeared. Recently he's being treated adult Atopic Dermatitis with satisfaction

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.29 no.4
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• pp.34-60
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• 2016

Objectives : The purpose of this study is to review Korean and Western medical papers on wart treatment. Methods : We searched papers published until 2015 via OASIS and KISS with the keyword "wart". In particular, OASIS is for searching Korean medicine and KISS for Western medicine articles. We exclude results that are inconsistent with established criteria. Results : The total number of papers on wart treatment in korean medicine was 10, and it includes 7 case studies, 2 original research article and 1 statistical analysis. The ones in Western medicine was 42 and it consists of 27 origianl research articles, 10 case studies, 4 comparative studies and 1 clinical study. 'Flat wart' accounts for 50.0% and it made up the biggest portion of the type of warts in Korean medicine, while the percentage of 'various warts' was 40.5% in Western medicine. 'Herbal medicine' accounts for 10(100.0%) and it made up the biggest portion of the the type of treatment in Korean medicine, while the percentage of 'cryo therapy' was 7(16.7%) in Western medicine. The various types of treatment are more introduced on Western than on Korean medicine papers. However, therapy suggested by Western medicine has more side effects than the one introduced by Korean medicine. Conclusions : We hope this article would encourage further research on treatment for warts in Korean medicine.

• Archives of Plastic Surgery
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• v.38 no.6
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• pp.798-802
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• 2011

Purpose: A wart is caused by epidermal infection with the human papilloma virus. Although wart naturally disappears in some cases, it require treatment because of pain, aesthetic problem, and the possibility of malignant change. Conventional non-surgical treatment cannot be a fundamental solution for the pain and has such disadvantages as frequent recurrence and difficulties in achieving a satisfactory outcome. A surgical procedure was performed on patients with wart and the procedure had a good outcome. Methods: We investigated the gender, age, lesion site, mean treatment duration, and presence or absence of recurrence in 21 patients with a wart within the period of January 2007 to July 2011. For local lesions, primary closure, including subcuticular suture after the excision, was performed. If the defect size was too big to do primary closure, we performed rotation flap. For wide multiple lesions, a split thickness skin graft was performed. Results: Among the 21 patients, 12 patients were male and 9 patients were female, and their mean age was 42 years (SD=17.38, range: 11~75 years). The lesion site was the foot in 10 patients, the hand in 8 patients, the face in 2 patients, and the scalp in 1 patient. The mean treatment duration was 13.5 days (SD=4.36, range: 6~15 days) for the primary closure or rotation flap, and 18.5 days (SD=2.12, range: 17~20 days) for the skin graft. 20 patients were cured without recurrence. No recurrence was observed in the patients who underwent primary closure or rotation flap. One of the two patients who underwent a skin graft of their wart that had covered their entire palm had local recurrence in part of her finger tips. Conclusion: We performed surgical procedure on recalcitrant wart. As a results, we can treat it with short treatment duration, low recurrence rate and less scarring and get high patient satisfaction.

• Radiation Oncology Journal
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• v.15 no.3
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• pp.187-195
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• 1997

Purpose : To analyze the involvement of apoptosis regulatory genes p53, $p21^{wart/cip1}$ bax and bcl-2 in induction of apoptosis by radiation in murine tumors. Materials and methods : The radiation-sensitive ovarian carcinoma OCa-1, and the radiation-resistant hepatocarcinorna HCa-I were used. Tumors, 8 mm in diameter, were irradiated with 25 Gy and at various times after irradiation, ranging from 1 to 48 h, were analyzed histologically for apoptosis and by western blot for alterations in the expression of these genes. The p53 status of the tumors were determined by the polymerase chain reaction-single strand conformation polymorphism assay. Results : Both tumors were positive for wild-type p53. Radiation inducesd apoptosis in OCa-1 but not in HCa-1. Apoptosis developed rapidly, peaked at 2 h after irradiation and returned to almost the background level at 48 h In OCa-1 radiation upregulated the expression of p53, $p21^{wart/cip1}$. and the bcl-2/bax ratio was decreased. In HCa-1 radiation increased the expression of both p53 and $p21^{wart/cip1}$, although the increase of the latter was small The bcl-2/bax ratio was greatly increased. In general the observed changes occurred within a few hours after irradiation, and either preceded or coincided with development of apoptosis Conclusions : The development of apoptosis required upregulation of both p53 and $p21^{wart/cip1}$ as well as a decrease in bcl-2/bax ratio. In contrast, an increase in bcl-2/bax ratio Prevented apoptosis in the presence of upregulated p53 and $p21^{wart/cip1}$ . These findings indentified the involvement of multiple oncogenes in apoptosis regulation in vivo and demonstrate the complexity that may be associated with the use of a single oncogene assessment for Predicting the outcome of cancer therapy with cytotoxic agents.

• The Journal of Pediatrics of Korean Medicine
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• v.30 no.4
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• pp.111-122
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• 2016

Objective The purpose of this study is to investigate recent clinical studies on the effect of herbal medicine in flat warts in China, and to seek better methods to treat and study for flat warts in Korea. Methods The clinical studies from the CAJ (China Academic Journal) of CNKI (China National Knowledge Infrastructure) by key words '扁平疣' in recent 5 years (From January 2011 to December 2015) were searched. Results 16 articles were selected from 122 clinical studies, and analyzed. The most commonly used herbs were Isatidis Radix (板藍根), Equiseti Hiemalis Herba (木賊), Cyperi Rhizoma (香附子), Carthami Flos (紅花), Glycyrrhizae Radix (甘草) etc., and the articles all showed effectiveness over the control group. Conclusion Based on analyzing the studies, herbal medicine has shown effective in flat wart. This study may be useful not only as clinical data, but also to determine better treatment going forward.

• The Journal of Korean Medicine
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• v.42 no.4
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• pp.238-243
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• 2021

Objectives: Plantar wart is a common viral skin disease caused by human papillomavirus infection and poses a therapeutic challenge in the paediatric patient population. Acupuncture and moxibustion are effective treatments for a wide range of skin conditions. Case report: This study presents the case of a 9-year-old girl for whom complete resolution of recalcitrant warts was achieved with acupuncture and moxibustion treatment. Results: After 20-week treatment, the wart lesions and pain were completely resolved. At the 6-month follow-up, the lesions remained fully resolved. Conclusion: This result suggests that acupuncture and moxibustion could be effective therapeutic strategies for plantar warts.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.16 no.1
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• pp.226-235
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• 2003

The relapsed patient who has diagnosed flat wart and treated with continuous immunotherapy in Western Dermatology come to Dongshin University Oriental Medical hospital OPD Ophthalmology and Otolaryngology from 23 December 2002 to 18 March 2003. We diagnosed as Gi(氣) deficiency and stagnation of damp. stagnation of Gi(氣) and blood stasis caused by insufficiency of Yang of the spleen treated with Gamiijungtang(加味理中湯) and Sodogeumgagam(消毒飮加減). As a result, we got the attentive effect and report on a paper.