• 한국정밀공학회지
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• 제14권2호
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• pp.102-112
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• 1997

This paper describes the method that can construct kinematically admissible velocity fields for forging of gear-like components which have tooth shape around the cylinder. The kinematically admissible velo- city fields for the various gear-like components, involute spur gear, trapezoidal spline, square spline, ser- ration and trochoidal gear, were constructed by pilling up the velocity components according to the shape of tooth and billet. The billets, of hollow and solid, were Al 2218 and 2024. To verify the method, the analyses and experiments were carried out and compared with each other. For analyses, the half pitches of com- ponents were divided into several deformation regions based on their tooth profile. A neutral surface was used to represent the inner flow of material during forging. Its location varied with the energy optimazation and its contour varied with the number of teeth. In experiment, the contour of material filling up the tooth zone is hyperbolic curve caused by the frictional drag on the interface of die-wall/workpiece but, in the analysis, it is an arc which retains the same contour during all forging operation.

• 약학회지
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• 제56권6호
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• pp.366-371
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• 2012

In this present study, we determined whether or not there is an immunoadjuvant effect of ochnaflavone, a biflavone isolated from Lonicera japonica. As an antigenic source, the cell wall (CACW) of Candida albicans, a fungal pathogen, was used. CACW consists of 95% carbohydrate (mannan). In the experiments, BALB/c mice were immunized with emersion forms of CACW combined with or without ochnaflavone (Och) in the presence of IFA containing mineral oil or CACW alone. Then, the amounts of antisera collected from these mice groups were measured by the ELISA method. Data from these experiments showed that CACW combined with Och (CACW/Och/IFA) provoked the production of antisera app. 2.2 or 5 times more than the corresponding CACW/IFA or CACW alone (CACW/DPBS), respectively, in mice (P<0.05). We further examined the immune response type induced by Och. Analysis of the values of the IgG1/IgG2a ratios obtained from IgG isotyping revealed that Och induced Th2-immunity more dominantly than Th1. This finding was confirmed by cytokine profile. CACW/Och/IFA formulation induced IL-4 (Th2-type cytokine) more than IFN${\gamma}$ (Th1-type cytokine) as compared with CACW/IFA and CACW/DPBS formulations (P<0.05). All data combined, Och appears to have an immunoadjuvant activity that may convert Th1 immunity into Th2 immunity.

• 대한기계학회논문집B
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• 제34권6호
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• pp.569-577
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• 2010

다상 유체 시스템에 적용할 수 있는 다중스케일 입자 시뮬레이션 기법을 개발하였다. 거시 모델과 미시모델이 만나는 경계영역에서 세가지로 구별되는 기능을 수행하도록 하였다. 먼저, 기상과 액상을 분리하여 연결하기 위해 벽을 설정하였다. 또 경계영역을 근처에서 경계의 위치를 측정하고 이것에 벽의 각도와 위치가 연동하여 접촉각 값을 미시모델에서 거시모델로 전달하게 하였다. 마지막으로, 입자의 삽입과 제거를 통해 경계영역의 질량과 온도를 거시적 조건에 맞추도록 하였다. 이 알고리즘들을 적용한 완전습윤과 부분습윤시스템들은 좋은 결합 결과를 보였다.

• Asian-Australasian Journal of Animal Sciences
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• 제6권4호
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• pp.619-622
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• 1993

Rumen bacterial amino acids in sheep on urea diet were monitored to assess a possible change in amino acid synthesis as a long term response to high rumen ammonia environment. A sheep was fed a semipurified diet with soybean meal, followed by a diet with urea as a main nitrogen source. Mixed rumen bacteria were harvested from ruminal fluid taken 3 h after feeding (twice in soybean meal feeding and 6 times in urea feeding) and fractionated as cell wall, proteins and protein-free cell supernatant of monitor amino acids in each fraction. Ruminal ammonia concentration at the sampling ranged from 5.7 to 39.5 mgN/dl. Cell wall and protein fractions of mixed rumen bacteria were stable in their amino acid composition regardless of nitrogen sources of diet and the feeding duration. However, protein-free cell supernatant fraction showed a higher alanine proportion with urea feeding (18.6 and 28.2 molar % of alanine for samples from sheep fed soybean meal and urea, respectively) and its duration (20.6 and 32.9 molar % for samples from sheep on urea diet for 1 and 65 days, respectively). Total free amino acid level of bacteria was depressed in the initial period of urea feeding but restored on 65th day of the feeding. These results suggest that an alanine synthesizing system may develop in rumen bacteria as urea feeding becomes longer.

• Nutrition Research and Practice
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• 제3권2호
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• pp.102-107
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• 2009

Fish oil and shortening have been suggested to have opposite effects on cardiovascular disease (CVD). This study investigated the effect of shortening and fish oil on CVD risk factors and aorta histopathology, and the association between risk factors and aorta histopathology. Male Wister rats (n=30) were fed an AIN-93G diet containing 20% fat in the form of fish oil, shortening, or soybean oil for 4 weeks. Total cholesterol (TC), triacylglyceride (TG), and C-reactive protein levels were significantly (P<0.001) lower in the fish oil than in soybean oil and shortening groups. HDL-cholesterol concentrations were significantly different (P<0.001) between groups. In addition, LDL-cholesterol levels were significantly (P<0.001) lower in the fish oil and shortening groups than in the soybean oil group. Insulin and glucose concentrations did not differ among groups. Effect of dietary fat on tissue fatty acid composition significantly differed in abdominal fat and brain compared with RBC, heart, kidney and liver. The aortic wall was significantly (P=0.02) thinner in the fish oil group than in the soybean oil and shortening groups. The aortic wall thickness was positively correlated with TG and TC, but negatively with EPA + DHA levels of all tissues. These results suggested that fish oil had protective effects on aorta histopathology by hypolipidemic action in this rat model.

• Journal of the Korean Wood Science and Technology
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• 제44권2호
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• pp.283-293
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• 2016

Owing to an increase in the air tightness of recent buildings, the natural ventilation rate was significantly lowered and the removal of accumulated moisture became difficult in these buildings. The hygrothermal performance of these buildings should be carefully considered to provide comfortable indoor environment by removing the moisture condensation risk and the mold growth potential. In this study, hygrothermal performance of two selected wall structures was investigated based on WUFI simulation program. The results displayed that the indoor temperature had impact on the moisture accumulation in the insulation layer for both modeled walls, showing that lower indoor temperature resulted in higher moisture accumulation, especially in the wood frame structure. Also, the yearly moisture accumulation profile exhibited a downward shift throughout the year by adding a vapour retarder with a lower sd-value. In addition, both of the two walls have condensation risk in winter, due to low temperature level. The wood frame structure has a bigger fluctuation and higher condensation risk than the concrete structure.

• 한국추진공학회지
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• 제12권2호
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• pp.33-39
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• 2008

초음속 연소에서 혼합 효율을 높이면서 전압력 손실을 줄일 수 있는 혼합기에 관한 연구가 수십 년동안 진행되어 왔으며, 본 논문에서는 이를 만족할 수 있는 새로운 개념의 혼합기를 고안하여 그 성능을 수치해석을 통하여 분석하였다. 후면 계단 혼합기를 비교 대상으로 압력과 등밀도선, 유선구조를 분석하였다. 공동이나 탭에서 발생하는 충격파가 후류로 전파되는 것과 달리, 벤트 혼합기의 구멍에서 발생하는 충격파는 벤트 혼합기 끝단에서 형성되는 팽창파에 의해 전파되지 못하며, 후류부의 재순환 영역으로 인해 경계층이 증가하며 이로 인해 후면 계단 방식에 비해 약한 충격파가 형성된다. 따라서 충격파로 인한 전압력 손실을 줄일 수 있으며, 구멍을 통한 공기 유입은 다수의 재순환 영역을 형성하여 혼합 효율을 증대시킨다. 또한 후류부에서 유동 흐름이 전반적으로 안정화되는 것을 볼 수 있다.

• Korea-Australia Rheology Journal
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• 제16권2호
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• pp.101-108
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• 2004

The hemodynamics behavior of the blood flow is influenced by the presence of the arterial stenosis. If the stenosis is present in an artery, normal blood flow is disturbed. In the present study, the characteristics of pulsatile flow in the blood vessel with stenosis are investigated by the finite volume method. For the validation of numerical model, the computation results are compared with the experimental ones of Ojha et al. in the case of 45％ stenosis with a trapezoidal profile. Comparisons between the measured and the computed velocity profiles are favorable to our solutions. Finally, the effects of stenosis severity and wall shear stress are discussed in the present computational analysis. It can be seen, where the non-dimensional peak velocity is displayed for all the stenosis models at a given severity of stenosis, that it is exponentially increased. Although the stenosis and the boundary conditions are all symmetric, the asymmetric flow can be detected in the more than 57％ stenosis. The instability by a three-dimensional symmetry-breaking leads to the asymmetric separation and the intense swirling motion downstream of the stenosis.

• Journal of Mechanical Science and Technology
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• 제18권2호
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• pp.313-324
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• 2004

A rich phenomenon in the dynamics of azimuthal vortices in a circular cylinder caused by the inertial oscillation is investigated numerically at high Reynolds numbers and moderate Rossby numbers. In the actual spin-up flow where both the Ekman circulation and the bottom friction effects are included, the first appearance of a seed vortex is generated by the Ekman boundary-layer on the bottom wall and the subsequent roll-up near the corner bounded by the side wall. The existence of the small vortex then rapidly propagates toward the inviscid region and induces a complicated pattern in the distribution of azimuthal vorticity, i.e. inertial oscillation. The inertial oscillation however does not deteriorate the classical Ekman-pumping model in the time scale larger than that of the oscillatory motion. Motions of single vortex and a pair of vortices are further investigated under a slip boundary-condition on the solid walls. For the case of single vortex, repeated change of the vorticity sign is observed together with typical propagation of inertial waves. For the case of a pair of vortices with a two-step profile in the initial azimuthal velocity, the vortices' movement toward the outer region is resisted by the crescent-shape vortices surrounding the pair. After touching the border between the core and outer regions, the pair vortices weaken very fast.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2000년도 춘계학술대회논문집
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• pp.123-128
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• 2000

Fundamental and informative data of axi-symmetric stretch-drawing of several sheetmetals with thicknesses of 0.7-1.0mm are presented both for single and double operations. Very small radius is applied to the die profile (or-shoulder) ion all operations. to induce wall-thinning by the effect of bending-under-tension from which the name 'stretch-drawing' comes. It is clearly demonstrated that deeper cups could be formed by single and double stretch-drawings from smaller circular blanks due to such wall-thinning action than in the usual deep-drawing of larger blanks, From this fact it is emphasized that the deep-drawability of a sheet metal is not evaluated simply by the conventional L.D.R (limiting drawing ratio) but the depth of the drawn cup should also be taken into account./ Many experimental data about various metals and thicknesses given in this paper offer a valuable information in this process for more general use which recommends to replace the conventional deep-drawing process by the stretch-drawing process both for single and double operations. In the single stretch-drawing it is also confirmed that a deeper cup can be produced by raising the blank-holding force at later stage of operation.