• Animal cells and systems
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• v.9 no.3
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• pp.145-152
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• 2005

A retrograde tracer, WGA-apo-HRP-gold, was injected into midline thalamic nuclei and subsequently orexin-A immunostaining was performed on the tuberal region of the hypothalamus in order to investigate orexinergic projections to the midline thalamus. Injection site was targeted within one specific region, i.e., paraventricular, centromedian, rhomboid, reuniens, or intermediodorsal nucleus, but it proved to be either one or a combination of these thalamic nuclei. The distribution of WG/orexin-double-labeled neurons exhibited a general pattern in that the majority of labeled cells were observed within the ventral portion of the lateral hypothalamus as well as the perifornical nucleus (PeF). A small number of double-labeled cells were also observed at the dorsomedial nucleus, the area dorsal to the PeF, dorsal portion of the lateral hypothalamus, and the posterior hypothalamus. These orexin-immunoreactive neurons might have wake-related influences over a variety of functions related with midline thalamic nuclei, which include autonomic control, associative cortical functions, and limbic regulation.

• International Journal of Fluid Machinery and Systems
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• v.9 no.1
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• pp.95-106
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• 2016

A method of optimization design for the blade profile of a centrifugal impeller by controlling velocity distribution is presented, and a plenum fan is successfully designed. This method is based on the inner flow calculation inside the centrifugal impeller, and is related to the distribution of relative velocity. The results show that after optimization, the boundary layer separation on the suction surface has been inhibited and the stability of plenum fan is improved. The flow at the impeller outlet is also studied, and the jet-wake pattern at the impeller outlet is improved obviously by optimization. The calculation result shows that the static pressure and static pressure efficiency can be increased by 15.4% and 21.4% respectively.

• Bulletin of the Society of Naval Architects of Korea
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• v.24 no.2
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• pp.11-19
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• 1987

A Series 60, $C_b=0.60$ model was tested in the towing tank of Seoul National University. Total resistance, hull attitude, wake distributions and wave measured at FR condition(free trim and sinkage) and FX condition(fixed trim and sinkage). From the measured data, residual, viscous and wave pattern resistance components were evaluated and compared. It is found that the changes in wetted surface area should be considered in predictions of frictional resistances, and can be easily found from hydrostatic data and measured mean sinkages without additional tests. Applications of the concept to the geosim tests of Series 60, Wigley, Lucy Ashton models show that the conventional extrapolation method can be improved considerably.

• Sleep Medicine and Psychophysiology
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• v.13 no.1
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• pp.15-21
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• 2006

Introduction: The objective of the present study was to investigate bedtime, rise time and time-in-bed of Korean college students, separately on weekday and on weekend and to compare them. In addition, this study also aimed to evaluate the influence of gender, age and grade on the above sleep parmeters in Korean college students. Methods: Information regarding bedtime and rise time, separately on weekday and on weekend, of Korean college students were obtained by self-administered questionnaire. Questionnaires of 1,825 students (1,416 females and 409 males, age 18-30；mean age $21.1{\pm}2.2$) were used for statistical analyses. Results: Korean college students retired to bed 50 minutes later (00：49 on weekday；01：40 on weekend；t=39.67, p<0.001), rose 1 hour 58 minutes later (07：52 on weekday；09：50 on weekend；t=39.46, p<0.001), and slept 1 hour 8 minutes longer (t=13.33, p<0.001) on weekend. Compared to male students, female students had earlier rise time (t=8.96, p<0.01；t=3.89, p<0.01) and earlier bedtime both on weekday and weekend (t=7.10, p<0.01；t=6.04, p<0.01), and shorter time-in-bed on weekday (t=1.99, p<0.01). In addition, rise time delay and time-in-bed increase on weekend were more prominent in female students than in male students (t=3.41, p<0.01; t=3.68, p<0.01). Grade was correlated with bedtime and rise time on weekday (${\beta}=0.1022$, p<0.01；${\beta}=0.1009$, p<0.01), bedtime and time-in-bed on weekend (${\beta}=0.1096$, p<0.01；${\beta}=-0.0990$, p<0.01), and differences between week-day and weekend of the rise time and the time-in-bed (${\beta}=-0.0906$, p<0.01；${\beta}=-0.1115$, p=0.02). Conclusions: In this study, Korean college students had earlier bedtime/rise time and shorter time-in-bed on weekday than on weekend. These findings suggest that weekday sleep-wake schedule of Korean college students may be advanced relative to their biological sleep-wake cycle and that this discrepancy may be associated with weekday sleep deprivation. In addition, differences of sleep patterns between weekday and weekend were more prominent in female students and students with lower grade. Therefore, discrepancy between weekday sleep-wake schedule and biological sleep-wake cycle, as well as weekday sleep deprivation, might be more serious in female or lower-grade students.

• Journal of Internet Computing and Services
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• v.17 no.1
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• pp.35-45
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• 2016

Melatonin hormone involved in human's circadian rhythm adjustment sensitively responds to light's specific short wavelength ratio. A shift worker's circadian rhythm disturbance and sleep disorder are caused by the existing lighting conditions, whose short wavelength ratio is fixed. The life pattern of a shift worker changes irregularly because of irregular working hours and the same lighting environment; thus, his/her concentration is reduced. For such a reason, negative effects ensue to the detriment of healthy everyday life, including a high risk of accidents or having unsound sleep after leaving work. A smartphone-based wavelength control LED lighting system that targets shift workers and that can easily measure and control lighting suitable for wake-sleep cycle, according to working hours and closing hours, is proposed in this paper. First, after the light characteristics of LED lighting that changes depending on light control ratio are measured through the color sensor installed on the smartphone and the externally-linked Mini-Spectrometer, they are stored in the database. Based on the stored optical characteristics data, the measurement module and light control module are implemented. Lighting is offered using a control ratio having the maximum rate of short wavelength in consideration of the target illuminance, classified according to work type by identifying working hours as time when waking is required for shift workers. After a shift work leaves work, the amount of lighting is varied, using a control ratio having a minimum short wavelength rate so that a shift worker can enter the sleep state naturally.

• Particle and aerosol research
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• v.17 no.4
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• pp.81-89
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• 2021

Understanding particle-laden flow around cylindrical bodies is essential for the better design of various applications such as filters. In this study, laminar flows around two tandem cylinders and the motions of particles in the flow are numerically investigated at low Reynolds numbers. We aim to reveal the effects of the spacing between cylinders, Reynolds number and particle Stokes number on the characteristics of particle trajectories. When the cylinders are placed close, the unsteady flow inside the inter-cylinder gap at Re = 100 shows a considerable modification. However, the steady recirculation flow in the wake at Re = 10 and 40 shows an insignificant change. The change in the flow structure leads to the variation of particle dispersion pattern, particularly of small Stokes number particles. However, the dispersion of particles with a large Stokes number is hardly affected by the flow structure. As a result, few particles are observed in the cylinder gap regardless of the cylinder spacing and the Reynolds number. The deposition efficiency of the upstream cylinder shows no difference from that of a single cylinder, increasing as the Stokes number increases. However, the deposition on the downstream cylinder is found only at Re = 100 with large spacing. At this time, the deposition efficiency is generally small compared to that of an upstream cylinder, and the deposition location is also changed with no deposited particles near the stagnation point.

• Journal of the Society of Naval Architects of Korea
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• v.43 no.3 s.147
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• pp.322-330
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• 2006

Numerical calculations are carried out for flow past a circular cylinder forced oscillating normal to the free-stream flow at a fixed Reynolds number equal to 185. The cylinder oscillation frequency ranged from 0.8 to 1.2 of the natural vortex-shedding frequency, and the oscillation amplitude extended up to 20% of the cylinder diameter. IBM (Immersed Boundary Method) with direct momentum forcing was adopted to handle both of a stationary and an oscillating cylinder Present results such as time histories of drag and lift coefficients for both stationary and oscillating cases are in good agreement with previous numerical and experimental results. The instantaneous wake patterns of oscillating cylinder with different oscillating frequency ratios showed the synchronized wakes pattern in the lock-in region and vortex switching phenomenon at higher frequency ratio than the critical frequency ratio.

• Journal of computational fluids engineering
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• v.21 no.2
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• pp.81-89
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• 2016

Numerical simulations are carried out for the fluid flow and particle transport around two nearby circular cylinders in a side-by-side arrangement. The present study aims to understand the effects of the particle Stokes number and the spacing between two cylinders on particle dispersion and deposition characteristics. Simulations are based on an Eulerian-Lagrangian approach where the motion of particles is calculated by a Lagrangian approach based on one-way coupling. Results show that the flow structure is very different depending on the cylinder spacing, eventually affecting the overall pattern of particle dispersion significantly. It is also found that particles with smaller Stokes number tend to be distributed more uniformly in the wake of two cylinders, being located even inside the vortex cores. Meanwhile, particle deposition is analyzed in terms of the deposition efficiency and deposition location. The deposition efficiency of particles strongly depends on the Stokes number, whereas it is slightly affected by the cylinder spacing. The deposition location gets wider as the Stokes number increases, and it becomes asymmetric about the center of each cylinder as the cylinders get close.

• Journal of Ocean Engineering and Technology
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• v.24 no.5
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• pp.8-15
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• 2010

The flow around a two-dimensional, rectangular cylinder that is freely falling in a channel was simulated using the immersed boundary method with direct forcing to determine the interactions between the fluid and the structure. The results of the present study were in good agreement with previous experimental results. Regardless of the H/L ratio (where H and L are the height and width of the rectangular cylinder, respectively), the flow structures had essentially the same pattern as the two symmetrical circulations that form about the horizontal center of the cylinder, with those centers located at each lateral position near the wake. When the cylinder approaches very close to the bottom, a jet-like flow appeared between the bottom of the rectangular cylinder and the channel. When the jet-like flow goes through the channel, surrounding fluids are sucked into this jet, forming the secondary vortices.

• Journal of computational fluids engineering
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• v.6 no.4
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• pp.26-34
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• 2001

The flow past a circular cylinder forced to vibrate transversely is numerically simulated by solving the two-dimensional Navier-Stokes equations modified by the vibration velocity of a circular cylinder at a Reynolds number of 164. The higher-order finite difference scheme is employed for the spatial discretization along with the second order Adams-Bashforth and the first order backward-Euler time integration. The calculated cylinder vibration frequency is between 0.60 and 1.30 times of the natural vortex-shedding frequency. The calculated oscillation amplitude extends to 25% of the cylinder diameter and in the case of the lock-in region it is 60%. It is made clear that the cylinder oscillation has influence on the wake pattern, the time histories of the drag and lift forces, power spectral density and phase diagrams, etc. It is found that these results include both the periodic (lock-in) and the quasi-periodic (non-lock-in) state. The vortex shedding frequency equals the driving frequency in the lock-in region but is independent in the non-lock-in region. The mean drag and the maximum lift coefficient increase with the increase of the forcing amplitude in the lock-in state. The lock-in boundaries are also established from the present direct numerical simulation.