• 대한기계학회:학술대회논문집
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• 대한기계학회 2002년도 학술대회지
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• pp.717-720
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• 2002

The present study is to evaluate the performances of flow velocity and wall shear stress in the stenosed coronary artery using human in vivo hemodynamic Parameters and computer simulation. Initial and follow-up coronary angiographics in the patients with angulated coronary stenosis are performed. Follow-up coronary angiogram demonstrated significant difference in the percent of diameter in the stenosed coronary between two groups ($Group\;1:\;40.3{\%},\;Group\;2:\;25.5{\%}$). Flow-velocity wave obtained from in vivo intracoronary Doppler ultrasound data is used for the boundary condition for the computer simulation. Spatial and temporal variations of flow velocity vector and recirculation area are drawn throughout the selected segment of coronary models. The WSS of pre- and post-intracoronary stenting are calculated from three-dimensional computer simulation. Then negative shear stresses area on 3D simulation we noted on the inner wall of the post-stenotic area before stenting. The negative WSS is disappeared after stenting. High spatial and temporal WSS before stenting fell into within physiologic WSS after stenting. This finding was prominent in Model 2. The present study suggest that hemodynamic forces exerted by pulsatile coronary circulation termed WSS might affect on the evolution of atherosclerosis within the angulated vascular curvature. The local recirculation area which has low or negative WSS, might lead to progression of atherosclerosis.

• 대한한방부인과학회지
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• 제18권3호
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• pp.110-126
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• 2005

Purpose : The Purpose of this research was to investigate the effects of antithrombotic activities of Wuslsan (WSS). Methods : Measure the effect which was given to blood flow rate through the regular volume of glass tube after the blood was diluted five times with ACD soulution. Antithrombotic effect was calculated as a percentage of the experimental animal figure protected from the paralysis of hind legs or death of the mouse that is caused from the administration of platelet aggregation regent. Being classified one group of eight mice, each of them was divided into Normal, Control, and WSS. The normal group supplied a saline solution and the control group brought the dextran extravasated blood after an hour of administering the saline solution. Also WSS was dissolved in 2ml saline solution and then we dosed it to the experimental mice with Oral Zonde one day before the experiment. After that, the mice were abstained from food. And then we gave a measured amount of it before an hour. Finally, it gave rise to dextran extravasated blood in the same way as the Control group. Results : The results were obtained as follows. WSS inhibited platelet aggregation induced by ADP and epinephrine significantly as compared with the control group. WSS showed fibrinolytic activity insignificantly as compared with the control group. WSS increased blood flow rate significantly as compared with the control group in vitro. WSS inhibited pulmonary embolism induced by collagen and Epinephrine(inhibitive rate is 37.5%). WSS increased number of platelet and fibrinogen amount significantly, and shortened PT and APTT as compared with the control group in thrombus model induced by dextran. Conclusion : WSS is effective antithrombotic activity from experimental result.

• International Journal of Vascular Biomedical Engineering
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• 제1권1호
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• pp.13-23
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• 2003

Backgrounds: The present study in angulated coronary stenosis was to evaluate the influence of velocity and wall shear stress (WSS) on coronary atherosclerosis, the changes of hemodynamic indices following coronary stenting, as well as their effect of evolving in-stent restenosis using human in vivo hemodynamic parameters and computed simulation quantitatively and qualitatively. Methods: Initial and follow-up coronary angiographies in the patients with angulated coronary stenosis were performed (n=80). Optimal coronary stenting in angulated coronary stenosis had two models: < 50 % angle changed(model 1, n=43), > 50% angle changed group (model 2, n=37) according to percent change of vascular angle between pre- and post-intracoronary stenting. Flow-velocity wave obtained from in vivo intracoronary Doppler study data was used for in vitro numerical simulation. Spatial and temporal patterns of velocity vector and recirculation area were drawn throughout the selected segment of coronary models. WSS of pre/post-intracoronary stenting were calculated from three-dimensional computer simulation. Results: Follow-up coronary angiogram demonstrated significant difference in the percent of diameter stenosis between two groups (group 1: $40.3{\pm}30.2$ vs. group 2: $25.5{\pm}22.5%$, p<0.05). Negative WSS area on 3D simulation, which is consistent with re-circulation area of velocity vector, was noted on the inner wall of post-stenotic area before stenting. The negative WSS was disappeared after stenting. High spatial and temporal WSS before stenting fell into within physiologic WSS after stenting. This finding was prominent in Model 2 (p<0.01) Conclusions: The present study suggests that hemodynamic forces exerted by pulsatile coronary circulation termed as WSS might affect on the evolution of atherosclerosis within the angulated vascular curvature. Moreover, geometric change, such as angular difference between pre / post-intracoronary stenting might give proper information of optimal hemodynamic charateristics for vascular repair after stenting.

• 대한토목학회논문집
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• 제41권1호
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• pp.65-74
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• 2021

앞으로 교통약자의 수가 더욱 증가할 것으로 예상되므로 노인, 장애인과 같은 교통약자를 위한 다양한 정책이 마련되어야 할 시점이다. 본 연구에서는 교통약자들의 보행안전만족도에 보행자의 개인 및 가구특성과 공공시설 접근성이 미치는 영향을 실증분석하고, 교통약자의 보행안전만족도를 향상시키기 위한 방안을 모색하여 포용적 도시환경 조성에 기여하고자 하였다. 분석결과, 노인의 보행안전만족도에는 연령, 성별 변수가 중요하였으며, 장애인의 보행안전만족도에는 학력이 중요한 요소였다. 노인과 장애인 모두 1인가구일수록, 소득이 많을수록, 광역시가 아닌 지역에 거주할수록 보행안전만족도가 증가하였다. 공공시설 접근성의 경우 공공기관 접근성에 만족할수록, 도시공원 및 녹지 접근성에 만족할수록, 대중교통 접근성에 만족할수록 노인과 장애인의 보행안전만족도가 증가하였다. 노인은 상업시설 접근성에 만족할수록 보행안전만족도가 높아졌으나, 의료시설 접근성에 만족할수록 오히려 보행만족도는 낮아졌다.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2000년도 제15차 학술회의논문집
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• pp.338-338
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• 2000

This paper proposes a modified TD-PSOLA algorithm for Korean speech synthesis. A WSS (Weighted score search) algorithm is proposed for pitch detection and speech synthesis engine is designed using 46 phones database.

• 대한방사선기술학회지:방사선기술과학
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• 제38권1호
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• pp.1-6
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• 2015

Whole spine scanography(WSS)는 전신에 X선을 조사하는 검사로 치료기간 동안 빈번한 X선 조사가 이루어지는 검사이다. 일반촬영 분야에서는 많은 X선이 전신에 조사되는 검사이다. 따라서 논문에서는 Auto image pasta기법의 디지털 WSS 검사에서 환자의 검사방향에 따른 유효선량과 장기선량을 전산모사를 통하여 평가하였고, 영상에서 척추의 확대도와 각도의 변화를 평가하였다. 전후면 자세에서의 평균 유효선량은 0.069 mSv였고, 후전면 자세에서 평균 유효선량은 0.0361 mSv로 약 2배의 차이를 보였다. 전후면 자세에서 남성의 평균 유효선량은 0.089 mSv, 여성에 대한 평균 유효선량은 0.431 mSv로 나타났고, 후전면 자세에서 남성의 평균 유효선량은 0.050 mSv, 여성에서는 0.026 mSv로 나타났다. 확대율에서는 후전면 자세에서 전후면 자세에 비해 5%정도 확대 되었으나 각도에는 큰 변화를 보이지 않았다. 따라서 임상 환경에서 동일한 검사조건에서 환자의 자세를 변화시키는 것만으로도 환자의 피폭선량을 감소시킬 수 있음을 확인하였다. 특히 WSS와 같이 치료기간 동안 반복되는 검사에서 환자의 피폭선량 최적화를 위하여 검사 프로토콜의 재정립이 필요함을 확인하였다.

• 한국방사선학회논문지
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• 제14권7호
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• pp.899-906
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• 2020

WSS 측면 검사는 척추의 질환을 진단하기 위해 매우 중요한 검사이다. 최근 대면적의 Long Length Detector가 보급되고 있어 피폭선량과 검사 시간을 효율적으로 줄일 수 있으며, 낙상 고위험군 환자 및 소아, 청소년기 환자의 검사에 매우 효율적으로 적용할 수 있다. 하지만 1회 조사로 영상을 얻기 때문에 기하학적인 척추의 해부학적 구조상 허리뼈 보다 목뼈 부근이 상대적으로 체적이 적어 목뼈 부위의 영상 품질은 진단 가치가 매우 하락한다는 단점이 있다. 이에 본 연구는 WSS 측면 검사에서 균일한 영상품질을 얻기 위해 3D 프린팅 기술과 구리 필라멘트를 이용하여 부가 필터를 제작하고 결과를 분석하고자 한다. 3D 프린팅 기술은 원하는 모양을 손쉽게 출력할 수 있는 장점이 있어 산업 분야 전반에 광범위하게 사용되고 있으며, 최근 구리 소재의 필라멘트가 개발되어 부가 필터로서의 가능성을 확인하였다. WSS 측면 검사에서 부가 필터 적용시 CNR과 SNR이 우수하게 측정되어 부가필터의 사용 가능성을 확인 하였다.

• 대한물리의학회지
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• 제16권1호
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• pp.23-31
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• 2021

PURPOSE: This study was conducted to identify the effects of altering foot position on quadriceps femoris including vastus medialis obliques (VMO), vastus lateralis (VL) and rectus femoris (RF) activation during wall squat exercises. METHODS: All subjects (n = 15) were selected and randomly performed three kinds of wall squats: 1) GWS (General Wall Squat), 2) WSS1/4 (Wall Squat Short 1/4), and 3) WSS1/2 (Wall Squat Short 1/2). Each subject completed all three kinds of wall squatting exercises at three different times and recorded the muscle activity data of vastus medialis obliques, vastus lateralis and rectus femoris. RESULTS: Compared with GWS exercise, VMO and RF muscle activity significantly increased under WSS1/2 exercise (p < .05), while only RF muscle activity significantly increased under WSS1/4 exercise (p < .05). CONCLUSION: The results of the present study indicate that moving the foot toward the wall during wall squats has a positive effect on quadriceps activation. The exercise of wall squat short can not only be used as the lower limb muscle strengthening training for normal people, but also as the recovery training for patellofemoral pain syndrome patients in the rehabilitation stage. Besides, Anterior cruciate ligament patients can also try this exercise according to the advice of doctors and therapists.

• 한국산학기술학회논문지
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• 제15권8호
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• pp.5288-5293
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• 2014

본 논문은 차세대 ROADM을 구성하는 핵심기술인 파장선택스위치에서 기존에 사용되는 MEMS소자 기술대신에 LCOS 디스플레이 기술을 적용한 파장선택스위치의 특성을 고찰한 논문이다. LCOS소자를 이용한 5개의 포트를 갖는 파장선택 스위치 시스템을 구성하고 응답특성과 빔제어 특성, insertion loss와 channel isolation등 파장선택 스위치로서의 기본적인 특성들을 검토하였다. 본 파장선택스위치의 응답특성은 11.6 mS 로 양호하며 LCOS상에서의 grating 이미지 패턴에 따른 입사빔의 편향특성이 잘 구현되었다. C밴드내의 40개 채널에 대한 Insertion loss 측정에서 채널에 따라 5.5~12.7 dB 사이의 값이 측정되었으며 인접채널간의 channel isolation 측정은 16~18 dB 값이 측정되었다. 기존의 MEMS소자를 이용한 파장선택스위치 상용화된 제품에 비해 특성은 아직 다소 부족하지만 향후 보완연구에 의해 LCOS소자를 이용한 파장선택스위치 시스템의 기술경쟁력이 충분히 확보될 것으로 기대한다.

• Journal of Korean Neurosurgical Society
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• 제62권2호
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• pp.183-192
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• 2019

Objective : The objective of this study was to analyze patient-specific blood flow in ruptured aneurysms using obtained non-Newtonian viscosity and to observe associated hemodynamic features and morphological effects. Methods : Five patients with acute subarachnoid hemorrhage caused by ruptured posterior communicating artery aneurysms were included in the study. Patients' blood samples were measured immediately after enrollment. Computational fluid dynamics (CFD) was conducted to evaluate viscosity distributions and wall shear stress (WSS) distributions using a patient-specific geometric model and shear-thinning viscosity properties. Results : Substantial viscosity change was found at the dome of the aneurysms studied when applying non-Newtonian blood viscosity measured at peak-systole and end-diastole. The maximal WSS of the non-Newtonian model on an aneurysm at peak-systole was approximately 16% lower compared to Newtonian fluid, and most of the hemodynamic features of Newtonian flow at the aneurysms were higher, except for minimal WSS value. However, the differences between the Newtonian and non-Newtonian flow were not statistically significant. Rupture point of an aneurysm showed low WSS regardless of Newtonian or non-Newtonian CFD analyses. Conclusion : By using measured non-Newtonian viscosity and geometry on patient-specific CFD analysis, morphologic differences in hemodynamic features, such as changes in whole blood viscosity and WSS, were observed. Therefore, measured non-Newtonian viscosity might be possibly useful to obtain patient-specific hemodynamic and morphologic result.