• 고령자･치매작업치료학회지
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• 제12권2호
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• pp.97-106
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• 2018

목적 마인드맵을 활용한 회상치료가 여성 치매 의심 노인의 인지기능과 우울 지수 및 삶의 질에 미치는 영향을 알아보고자 하였다. 연구방법 본 연구는 무작위 대조군 전 후 실험설계를 사용하였다. 연구 대상자는 여성 치매 의심 노인으로 실험군 7명, 대조군 7명으로 이루어져 있다. 모든 대상자는 중재 기간 동안 동일하게 20분간 그리기 활동에 참여하였고, 실험군은 추가로 마인드맵을 활용한 회상치료를 적용하였다. 마인드맵을 활용한 회상 치료는 5주간, 주 2회, 1회당 40분씩 총 10회기로 구성하였다. 중재 효과를 검증하기 위해 사용된 평가 도구로 인지기능은 간이 정신상태 검사-한국판(Mini-Mental State Examination Korean Version ; MMSE-K), 우울 지수는 벡 우울증 척도 한국판(Korean Version of Beck Depression Inventory ; K-BDI), 삶의 질은 한국판 세계보건기구 삶의 질 간편형 척도(Korean Version of the World Health Organization Quality of Life Scale Abbreviated Version ; WHOQOL-BREF)를 사용하였다. 결과 분석은 기술 통계와 맨-휘트니 검정(Mann-Whitney U test), 윌콕슨 부호 순위 검정(Wilcoxon signed rank test)을 시행하였다. 연구결과 중재 후 집단 내에서 인지기능, 우울 지수, 삶의 질에 유의한 차이가 있었고, 집단 간 에서는 인지 기능에 유의한 차이가 있었다. 결론 마인드맵을 활용한 회상치료가 여성 치매 의심 노인의 인지기능과 우울 지수 및 삶의 질에 긍정적인 효과가 있음을 확인하였다.

• 환경위생공학
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• 제20권2호
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• pp.47-55
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• 2005

The World Health Organization(WHO, 1998) and the United States Environmental Protection Agency (USEPA, 1992) recommended $2{\mu}\;guranium/{\ell}$ in drinking water as a guideline. The Korea Institute for Environmental Research recently reported that the radioactive pollution in ground water was almost negligible In Korea$(1999\~2002)$. Cs were cast into beads(2mm in wet form) and treated with hexamethylene diisocyanate for stability in acidic aqueous solution through cross-linking of the beads surfaces. The removal study was carried out in a static batch system and a flow system. In the static system, a certain amount of sample water was confined in a vessel and beads(dry weight 0.5g) were packed into it in order to adsorb uranium for a certain period of time. Afterwards the remaining uranium in water vessel was determined by inductively coupled plasma mass spectrometry. The effective pH range was 4 to 8. The smaller the size of beads, the better the removal efficiency. Furthemore, the lower the flow rates, the higher the removal efficiency. The results showed that chitosan beads can be effectively used for the removal of uranium contained in water.

• 여성건강간호학회지
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• 제22권4호
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• pp.297-307
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• 2016

Purpose: This study was to estimate salt preference and sodium intake of pregnant women, and identify the relationship between salt preference and sodium intake. Methods: Research design was a cross sectional correlational survey with 197 pregnant women who visited outpatient clinics for antenatal care. The sodium intake levels were estimated by the amounts of sodium intake using the 24-hour recall method and sodium concentration in spot urine. The data were analyzed using descriptive statistics, t-test, ANOVA and Pearson's correlation. Results: Sodium intake using 24-hour recall method was $3,504{\pm}1,359mg$. Sodium intake levels had statistically significant differences depending on income. The average amount of sodium in spot urine was $2,882{\pm}878mg/day$. Sodium excretion levels had statistically significant differences depending on whether participants had preexisting hypertension in their family history and Body Mass Index (BMI) pre-conception. Salt preference was $62.61{\pm}20.96$ out of 180 points. Salt preference had significant differences depending on income, parity, gestational age, BMI pre-conception and showed negative correlation with sodium quantity in spot urine. Conclusion: Sodium intake in pregnant women recommended by World Health Organization recommended is 175%. Salt preference was not significantly different between sodium intake levels, however it was negatively correlated with sodium quantity in spot urine among pregnant women.

• 한국사회복지학회:학술대회논문집
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• 한국사회복지학회 2003년도 추계학술대회 자료집
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• pp.395-405
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• 2003

최근 정신질환의 심각성과 정신보건의 증진에 대한 세계적 관심이 고조되면서 세계보건기구(WHO)와 미국 보건복지부(DHHS)에서는 잇달아 정신보건에 대한 연구 결과들을 발표하였다(United States Public Health Service Office of He Surgeon Central, 1999 & 2001, World Health Organization, 2001). 이러한 가운데 지난해 미국 정부는 대통령 직속의 정신보건위원회를 설립하여 현재 정신보건서비스제도가 드러내고 있는 다양한 문제점들을 파악, 분석하여 개선 방안들을 제안해 줄 것을 요청하였다. 미국 사회의 정신질환 및 정신보건과 관련된 서비스시스템을 개선하기 위한 이러한 획기적인 노력은 1997년 Carter대통령 쥐임 직후 구성된 정신보건위원회(President's Commission on Mental Health) 이후 약 25년 만에 이루어진 일로서 정신보건 분야뿐만 아니라 미국 사회 전반에 걸쳐 비상을 관심을 끌고 있다. 그리고 이러한 노력과 결과는 최근 들어 심각하게 노출되는 정신질환 및 사회병리 현상으로 어려움을 겪고있는 한국 사회에도 많은 시사점을 줄 수 있으리라 기대된다. 따라서 본 연구는 정신보건위원회의 활동을 중심으로 미국 사회의 정신보건에 대한 다양한 문제를 인식하고 이를 해결하기 위한 정신보건서비스제도 개선 방안을 고찰하는 것을 목적으로 한다. 연구의 주요 내용으로는 위원회의 설립 배경과 활동 경과, 정신보건제도의 다양한 문제점과 개혁 방안으로 구성되었다. 그리고 이러한 고찰은 우리나라 정신보건제도에 대한 인식과 발전 방향에 대한 새로운 조망을 도출해낼 수 있으리라 기대한다. 연구의 주요 방법으로는 각종 연구보고서와 기존 문헌을 이용한 문헌 연구를 활용하였으며, 기존 출간 자료나 통계에 밝혀지지 않은 사항은 정신보건위원회의 위원과의 직접 인터뷰를 통해 보완되었다.

• 한국전자거래학회지
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• 제24권1호
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• pp.105-120
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• 2019

세계보건기구(WHO)를 비롯해 세계 각국의 정부기관은 항생제 오남용에 따른 항생제 내성균 감염에 대해 심각하게 경고하며 이를 예방하기 위한 관리와 감시를 강화하고 있다. 하지만 감염을 확인하기 위한 감염균 배양에 수일의 시간이 소요되면서 격리와 접촉주의를 통한 감염확산 방지 효과가 떨어져 선제적 조치를 위한 신속하고 정확한 예측 및 추정방법이 요구되고 있다. 본 연구는 Electronic Health Records에 포함된 질병 진단내역과 항생제 처방내역을 neural embedding model과 matrix factorization을 통해 embedding 하였고, 이를 활용한 딥러닝 기반분류 예측 모형을 제안하였다. 항생제 내성균 감염의 주요 원인인 질병과 항생제 정보를 embedding하여 환자의 기본정보와 병원이용 정보에 추가했을 때 딥러닝 예측 모형의 f1-score는 0.525에서 0.617로 상승하였고, 딥러닝 모형은 Super Learner와 같은 기존 기계학습 모형보다 더 나은 성능을 보여주었다. 항생제 내성균 감염환자의 특성을 분석한 결과, 감염환자는 동일한 질병을 진단받은 비감염환자에 비교해 J01 계열 항생제 사용이 많았고 WHO 권고기준(DDD)을 크게 벗어나는 오남용 청구사례가 6.3배 이상 높게 나타났으며 항생제 오남용과 항생제 내성균 감염간의 높은 연관성이 발견되었다.

• Journal of Preventive Medicine and Public Health
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• 제49권6호
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• pp.394-405
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• 2016

Objectives: The survival outcomes of antiretroviral treatment (ART) programs have not been systematically evaluated at the state level in India. This retrospective study assessed the survival rates and factors associated with survival among adult human immunodeficiency virus (HIV)-infected patients in Andhra Pradesh, India. Methods: The present study used data from 139 679 HIV patients aged ${\geq}15$ years on ART who were registered from 2007 to 2011 and were followed up through December 2013. The primary end point was death of the patient. Mortality densities (per 1000 person-years) were calculated. Kaplan-Meier and Cox-regression models were used to estimate survival and explore the factors associated with survival. Results: The overall median follow-up time was 16.0 months (2.0 months for the deceased and 14.0 months for those lost to follow-up). Approximately 13.2% of those newly initiated on ART died during follow-up. Of those deaths, 56% occurred in the first three months. The crude mortality rate was 80.9 per 1000 person-years at risk. The CD4 count (adjusted hazard ratio [aHR],4.88; 95% confidence interval [CI], 4.36 to 5.46 for < $100cells/mm^3$ vs. > $350cells/mm^3$), functional status (aHR, 3.05; 95% CI, 2.82 to 3.30 for bedridden vs. normal), and body weight (aHR, 3.69; 95% CI, 3.42 to 3.97 for <45 kg vs. >60 kg) were strongly associated with the survival of HIV patients. Conclusions: The study findings revealed that high mortality was observed within the first three months of ART initiation. Patients with poor baseline clinical characteristics had a higher risk of mortality. Expanded testing and counseling should be encouraged, with the goal of ensuring early enrollment into the program followed by the initiation of ART in HIV-infected patients.

• 보건행정학회지
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• 제30권4호
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• pp.493-504
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• 2020

Background: There have been many studies on the associations between body mass index (BMI) and cognitive function. However, no study has ever compared the associations across the methods of categorizing BMI. In this study, we aimed to fill the gap in the previous studies and examine whether the obesity paradox is valid in the risk of cognitive function. Methods: Of the 10,254 people aged 45 and older from the Korean Longitudinal Study of Ageing from 2006 to 2016, 8,970 people were finalized as the study population. The dependent variable was whether a person has a normal cognitive function or not, and the independent variables of interest were BMI categorized by the World Health Organization Western Pacific Regional Office (WHO-WPRO) method, the WHO method, and a 10-group method. Covariates included sociodemographic factors, health behavior factors, and health status factors. A generalized linear mixed model analysis with a logit link was used. Results: In the adjusted model with all covariates, first, in the case of BMI categories of the WHO-WPRO method, underweight (odds ratio [OR], 1.16; 95% confidence interval [CI], 1.15-1.17), overweight (OR, 1.36; 95% CI, 1.35-1.36), and obese (OR, 1.34; 95% CI, 1.33-1.34) groups were more likely to have a normal cognitive function than a normal-weight group. Next, in the case of BMI categories of the WHO method, compared to a normal-weight group, underweight (OR, 1.15; 95% CI, 1.14-1.16) and overweight (OR, 1.06; 95% CI, 1.06-1.07) groups were more likely to have a normal cognitive function; however, obese (OR, 0.62; 95% CI, 0.61-0.63) group was less likely to have it. Lastly, in the case of the 10-group method, as BMI increased, the likelihood to have a normal cognitive function changed like a wave, reaching a global top at group-7 (26.5 kg/㎡ ≤ BMI <28.0 kg/㎡). Conclusion: The associations between BMI and cognitive function differed according to how BMI was categorized among people aged 45 and older in Korea, which suggests that cognitive function may be positively associated with BMI in some categories of BMI but negatively in its other categories. Health policies to reduce cognitive impairment need to consider this association between BMI and cognitive function.

• Journal of Chest Surgery
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• 제46권6호
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• pp.482-485
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• 2013

Plasmacytoma is a plasma cell neoplasm that locally infiltrates a bone or spreads to extramedullary areas. A new World Health Organization criterion defines solitary plasmacytoma of bone as a localized bone tumor consisting of plasma cells identical to those seen in plasma cell myeloma, which is manifested as a solitary osteolytic lesion in a radiological evaluation. Primary tumors of the sternum are generally malignant, and solitary plasmacytomas of the sternum are very rare tumors. We present herein the case of a patient who had a primary sternal tumor with solitary plasmacytoma and no evidence of multiple myeloma.

• 세라미스트
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• 제21권3호
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• pp.293-301
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• 2018

Paper-based analytical devices (${\mu}PAD$) are highly advantageous for portable diagnostic systems owing to their low costs and ease of use. ${\mu}PADs$ are considered as the best candidates for realizing the World Health Organization (WHO) ASSURED criteria: affordable, sensitive, specific, user-friendly, rapid and robust, equipment-free, and deliverable to end users. However, they have several limitations such as low sensitivity and accuracy. This article reports a mini review for a micro-fluidic paper-based analytical devices (${\mu}PAD$), especially for addressing low sensitivity and accuracy issues.

• Journal of Korean Neurosurgical Society
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• 제48권1호
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• pp.62-65
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• 2010

Since the World Health Organization (WHO) classification for central nervous system neoplasms was declared in 2000, chordoid glioma of the third ventricle has been noted as a newly recognized tumor for central nervous system neoplasms. Although there is not enough universal experience to know the nature of this tumor due to its rarity, the origin of chordoid glioma was guardedly proposed to be the ependymal cells of the third ventricle. Such an idea has been primarily based on the specific location of the tumor, that is, third ventricle, suprasellae, and hypothalamus. However, we report a rare case of histologically confirmed chordoid glioma located in the left thalamus, not attached to any of the midline structures having unusual neuroradiological characteristics.