• Journal of Korean Medicine Rehabilitation
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• v.21 no.2
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• pp.31-48
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• 2011

Objectives : In order to investigate the anti-obesity effects of Wolbi-tang(here in after referred to WBT) on the obese gene and obese inhibitory, C57BL/6 mice were induced by high-fat diet. Methods : C57BL/6 mice were divided into 5 groups(normal, only high-fat diet, high-fat diet with Reductil, high-fat diet with WBT 400, 200 mg/kg extract) and fed for 5 weeks. And observed body weight change, total cholesterol, low density lipoprotein cholesterol(LDL-cholesterol), high density lipoprotein cholesterol (HDL-cholesterol), triglyceride, glucose, leptin change, alanine transaminase(ALT), aspartate transaminase(AST), serum creatinine, the expression of ${\beta}3$-adrenergic receptor(${\beta}3AR$), leptin, uncoupling protein(UCP2) gene in 3T3-L1 adipocyte, 3T3-L1 adipocyte proliferation, histological analysis of adipose tissue and liver tissue. Results : 1. Refer to cell cytotoxicity, viability of human fibroblast cells(hFCs) showed not significant changes. 2. The amount of ALT, AST was decreased significantly in WBT 400 mg/kg, 200 mg/kg groups. The amount of creatinine showed not significant changes. 3. Body weight was decreased significantly in WBT 400 mg/kg, 200 mg/kg groups. 4. The amount of total cholesterol and triglyceride was decreased significantly in WBT 400 mg/kg, 200 mg/kg groups. LDL-cholesterol was decreased and HDL-cholesterol was increased significantly in WBT 400 mg/kg groups. 5. The amount of glucose was decreased significantly in WBT 400 mg/kg groups. 6. The amount of serum leptin was decreased significantly in WBT 400 mg/kg, 200 mg/kg groups. 7. The revelation of ${\beta}3AR$ in 3T3-L1 adipocyte was increased significantly in WBT $100{\mu}g/ml$, $50{\mu}g/ml$ groups. The revelation of leptin was decreased significantly in WBT $100{\mu}g/ml$, $50{\mu}g/ml$ groups. The revelation of UCP2 was decreased significantly in WBT $100{\mu}g/ml$ group. 8. 3T3-L1 adipocyte proliferation was decreased significantly in WBT $100{\mu}g/ml$, $50{\mu}g/ml$ groups. The size of adipocyte was decreased relative to the control group in WBT 400 mg/kg group. 9. The adipose vacuoles in liver tissue was decreased relative to the control group. Conclusions : These results suggested that WBT has inhibitory effects of obesity. WBT might be applicated on treatment of obesity and metabolic syndrome. Further studies analysing its effects were needed.

• The Journal of Internal Korean Medicine
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• v.28 no.3
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• pp.531-543
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• 2007

Backgrounds : Gastric cancer is one of the most frequent causes of cancer-related deaths worldwide. Gastric cancer patients frequently exhibit distant metastasis at the time of diagnosis and at present, there is no standard regimen after operation or chemotherapy to prevent metastasis and recurrences. Aims : The objective of the study was to compare the overall survival and disease free survival in patients treated with wheel balance therapy (WBT) with patients treated with WBT alone or the combination of WBT and conventional therapy and see if there were any significant improvements in survival between the two groups. Setting & Design : East-West Cancer Center at Daejeon University: retrospective study. Materials & Methods : We retrospectively analyzed 62 patients with stage III (40 patients) and stage IV (22 patients) gastric cancer who have received operation or chemotherapy 2 months prior to beginning WBT. The patients followed the WBT protocol which includes herbal medicine such as PSM capsules, OnePlus syrup, or HAD capsules which prevent metastasis and recurrences. Overall survival and disease free survival were analyzed and the patients were treated for 89.55 weeks and 49.27 weeks (median value) for stages III and IV, respectively. Statistical analysis used : Overall survival and disease free survival were estimated using the Kaplan-Meier method and the WBT and combination treatment arms were compared using the log rank test. Results : For stage III, the 3 year overall survival was 78.5% and disease free survival was 78.3%. Metastasis and recurrence occurred in 13 of 40 patients (32.5%). For stage IV, the 2 year overall survival was 18.2% and disease free survival was also 18.2%. Metastasis and recurrence occurred in 19 of 22 patients (86.4%). No significant difference was found statistically between the WBT alone and combination treatment arms though the combination regimen showed superiority (overall survival p=0.5093, disease free survival p=0.5175). Conclusions : WBT yielded satisfactory results in prolonging survival and preventing metastasis and recurrence in gastric cancer patients. The major treatment unit of WBT is composed of herbal medications (HAD, PSM capsules, OnePlus syrup) and a randomized, prospective study should be carried out using only this treatment unit in the future.

• The Journal of Society for e-Business Studies
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• v.3 no.2
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• pp.37-55
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• 1998

This study describes the works on development of a scenario-based WBT system of electronic commerce to introduce and activate electronic commerce in our society because it is mostly required to correctly understand electronic commerce and timely educate its users and technicians for entering into global electronic commerce that binds every commercial area regardless of the borders and nationalities. This system, WBT(Web - Based Training of Electronic commerce), consists of two parts. The one part provides a general concept of EC. This is developed to meet the needs of beginner for EC. The other is a simulator for cyber shopping mall. It is designed for teaching how to shop at cyber shopping mall based on various scenarios. In addition, we can simulate ourselves for EDI, which enables trading partners to conduct routine business transaction, such as purchase orders, invoices and shopping notices with it. Our commitment to the development of this application is consistent with the objectives of being easy to learn electronic commerce and its applications in real world.

• Journal of The Korean Association of Information Education
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• v.7 no.1
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• pp.91-101
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• 2003

The advantages of Web Based Training(WBT) are flexible delivery of training, easy distribution, security through registration and ease of content update. And WBT also provide a powerful instructional environment. An obvious instructional advantage of WBT is the ability to provide for the delivery rich multimedia to learners. In this paper, we have proposed the curricula for the Subjects of Computer Education in University. And We implemented the Web Based Training System for the Subjects of Computer Education including the proposed curricula. The Proposed system are composed of student's learning part, lecture's teaching part, and operator's management part. And we show the Effectiveness and Weakness of proposed system, based on the students answering about various questions related proposed system's effectiveness.

• Proceedings of the Korea Society for Simulation Conference
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• 2003.06a
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• pp.25-29
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• 2003

본 논문에서는 울진 표준형원전 시뮬레이터의 강의실용 교육훈련 시스템의 일원으로 개발된 CBT (Computer Based Training) 및 WBT (Web Based Training)에 대해 다루고 있다. CBT는 발전소 시뮬레이션, 노심 다이나믹스, 중대사고, 비상발령 및 증기발생기 열변환 과정으로 구성되어 있다. Simulator Operation 기능을 이용하면 강사는 강사조작 메뉴를 통하여 시뮬레이터를 조작을 할 수 있고, Sim-Diagram 등 각종 화면을 보여줄 수 있다. 중대사고는 모의사고에 의해 구축된 데이터를 근거로 하여 개발되었으며, 방사선 비상등급에 따라 백색비상, 청색비상, 적색비상으로 구성된 비상발령은 각 발령의 발령상황 등을 Open Window를 통하여 볼 수 있도록 하였다. 한편 WBT는 강사와 교육생이 강의실 이외의 장소에서 시간과 공간의 제약을 벗어나서 원격교육이 가능하도록 구축한 웹서버 환경이다. 현재는 기존에 구축된 강사들의 홈페이지를 Intra-Net환경에서 접근이 가능하도록 링크된 상태에 있다. 향후에는 일부내용에 대해서는 원격으로 강의가 가능하도록 다양한 컨텐츠를 개발할 예정이며, 현재는 발전소 운전과 관련한 교육자료, 각종 동영상 및 이미지, 각종교재 등에 대한 DB 구축을 준비중에 있다

• Journal of Korean Traditional Oncology
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• v.17 no.2
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• pp.1-16
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• 2012

Background : Integrative cancer treatment is a holistic approach embracing body, mind, and spirit incorporating conventional treatments of surgery, chemotherapy, radiation and personalized complementary treatments. Wheel Balance Therapy (WBT) of East-West Cancer Center(EWCC), Dunsan Oriental Hospital of Daejeon University was developed to balance out all factors involved in cancer care based on the traditional theories of oriental medicine. Objective : This work aims to analytically review literatures on WBT and its related components. Methods : Literatures published from January 1st, 1990 to April 30th, 2011 were reviewed focusing on 4 main components of WBT; herbal medicine, immune activation, anti-cancer diet, and breathing/meditation. Data were retrieved from medical search engines and electronic data bases including Pubmed, Research Information sharing Service (RISS), Korean-studies Information Service System (KISS), China National Knowledge Infrastructure (CNKI), and Korea's National Digital Library (KNDL). Results : In this review, EWCC's most commonly prescribed formulas are explored. The composition of the formulas, their use in clinical settings as well as the background studies and other therapeutic efficacies are explained. Information on incorporating anti-cancer dietary support and breathing and meditation techniques, other therapies practiced as part of the center's integrative cancer care are also covered. Conclusion : WBT based on holistic theories of oriental medicine embracing body, mind, and spirit is expected to further contribute in promotion of cancer patients' quality of life and prolonged survival time.

• Journal of Korean Traditional Oncology
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• v.20 no.2
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• pp.37-49
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• 2015

Objectives : Retroperitoneal liposarcoma (RPS) is a rare solid tumor and has a high recurrence rate after surgery. New complementary and alternative medicine is required to manage symptoms of RPS and side effects of surgery, chemotherapy and radiation therapy. The purpose of this case report is to report two cases of reduction of side effects of surgery and radiation therapy in RPS treated with Wheel Balanced Therapy (WBT) which is a traditional Korean medicine treatment program for patients with cancer. Methods : Two patients with RPS were treated with WBT. Each of patients received personalized WBT schedule including acupuncture. The changes in clinical and laboratory findings were evaluated. Results : The symptoms of patients were improved after about 2 weeks hospitalization. Conclusions : This case report suggests that WBT has a potential to treat side effects of surgery and radiation therapy in patients with RPS. Further rigorous studies are necessary to investigate the therapeutic effects of WBT on RPS.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 2003.09a
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• pp.58-61
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• 2003

This paper proposes e-Learning environments far digital circuit experiment. The e-Learning environments are implemented as a WBT system that includes the circuits monitoring system and the students management system. In the WBT client-server system, the instructor represents the server and students represent clients. The client computers are equipped with a digital circuit training board and connected to the server on the World Wide Web. The training board consists of a Programmable Logic Device (PLD) and measuring instruments. The instructor can reconfigure the PLD with various circuit designs from the server so that students can investigate signals from the training board. The instructor can monitor the progress of the students using Joint Test Action Grouo(JTAG) technology. We implement the WBT system and a courseware fo digital circuits and evaluation the environments.

• Korean Journal of Child Studies
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• v.22 no.2
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• pp.219-235
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• 2001

The purpose of this study was to provide guidelines for the effective operation of Web-Based Training (WBT) for early childhood teachers. Based on content analysis and questionnaires administered to the 174 current trainees, this research analyzed (1) the educational effectiveness and learner satisfaction, (2) the operation and management, and (3) the system, interface, interaction and communication, motivation and content design of $WBT^{***}$. Results showed that most trainees were very satisfied with the WBT because the program provided plentiful professional information enabling them to pursue their educational objectives along with flexibility of time and space. On the other hand, system stability, communication, motivation, and content design need to be improved. Based on the research results, 8 strategies of effective management of web-based early childhood teacher training were proposed.

• The Journal of Internal Korean Medicine
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• v.32 no.3
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• pp.458-464
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• 2011

Background : Advanced thymic cancer still remains as an intractable disease. The survival rate of advanced thymic cancer could be increased through chemotherapy and radiation, but the results have not been satisfactory. Objectives : To see whether wheel balanced therapy (WBT) has the therapeutic effects or not on advanced thymic cancer patient. Methods : A patient diagnosed with progression of thymic carcinoma with pleura metastasis visited the East-West Cancer Center (EWCC) on Feb 9th, 2011. The patient was treated with WBT for a period of 9 weeks from Feb 9th to Apr 16th. She stayed 6 weeks in hospital and took oriental medicine prescribed by EWCC. Computed tomography (CT) and blood test were used to evaluate the disease progression of the patient. Results : Mass of chest CT was stable for 2 months. The patient's quality of life improved during her hospital stay. Conclusions : This case study supports WBT may have efficacy in treating advanced thymic cancer patients.