• Journal of the Korea Society of Computer and Information
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• v.23 no.4
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• pp.147-153
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• 2018

In this paper, we propose an efficient WBC 14-Diff classification which performs using the WBC-ResNet-152, a type of CNN model. The main point of view is to use Super-pixel for the segmentation of the image of WBC, and to use ResNet for the classification of WBC. A total of 136,164 blood image samples (224x224) were grouped for image segmentation, training, training verification, and final test performance analysis. Image segmentation using super-pixels have different number of images for each classes, so weighted average was applied and therefore image segmentation error was low at 7.23%. Using the training data-set for training 50 times, and using soft-max classifier, TPR average of 80.3% for the training set of 8,827 images was achieved. Based on this, using verification data-set of 21,437 images, 14-Diff classification TPR average of normal WBCs were at 93.4% and TPR average of abnormal WBCs were at 83.3%. The result and methodology of this research demonstrates the usefulness of artificial intelligence technology in the blood cell image classification field. WBC-ResNet-152 based morphology approach is shown to be meaningful and worthwhile method. And based on stored medical data, in-depth diagnosis and early detection of curable diseases is expected to improve the quality of treatment.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.32 no.5
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• pp.422-430
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• 2010

Purpose: The aim of this study is that we evaluate the change of the White Blood Cell(WBC) count, Absolute Neutrophil Count (ANC), Erythrocyte Sedimentation Rate (ESR) and C-reactive Protein (CRP) values, and try to make standardization for postoperative sequels before and after the oral cancer resection and reconstructive surgery. Materials and Methods: The study was comprised of 34 patients (male 15, female 19) who were diagnosed as an oral cancer and had performed ablation and reconstructive surgery at Dankook university dental hos-pital. Each blood specimen was collected from patients and estimated WBC count, Neutrophil count, ESR, CRP on first, third, fifth, seventh day efore and after surgery and analyzing inter relationship between each value. Classifying Group I (resection with reconstructive surgery patients) and Group II (resection without reconstructive surgery patients). Also classifying group A (below 4 hours of operation time), Group B (4 to 8 hours of operation time), Group C (above 8 hours of operation time), each group was analyzed and compared. The Following results were induced. Results: (1) In coefficient of correlation, the CRP and WBC has highest value except WBC count and Neutrophil count. (2) There was no significant difference any lapse in the progress between Group I and II of WBC count, Neutrophil count, but the CRP shows statistically higher level in group I than group II at immediate postoperative day, and 1 to 5 days after surgery. (3) There is no significant difference any lapse in the progress between Group A, B, C of WBC count, Neutrophil count, but CRP shows statistically significant difference in 1 day, 3 days after surgery Conclusion: It should be suggested that, determination of CRP is most valuable parameter for postopera-tive management and determination of postoperative clinical changes than other parameter such as WBC count, neutrophil count, and ESR values in oral cancer patient after resection and reconstructive surgery, based on the results of this study.

• Journal of the Korean Society for Geothermal and Hydrothermal Energy
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• v.12 no.1
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• pp.1-6
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• 2016

Characteristics of exhaust from chimney of electricity generator are analyzed based on CFD when Waveguide-Below-Cutoff (WBC) array is installed in order to achieve the certain level of electromagnetic pulse (EMP) shielding. The main purpose is prediction of average and maximum velocity of exhaust. The results reveal that: 1) When the specification of waveguide is given as 80-diameter, 400-length, and the gap of 20 mm, the shielding effectiveness (SE) is 140dB. The average and maximum velocity of exhaust in the chimney with WBC Array can be represented as exponential functions. 2) As the number of WBC increases, the velocity in the chimney dwindles. 3) Under the situation that WBC with 80 mm diameter is located at intervals of 20 mm, the average velocity can be approximated by $25.5344{\times}e^{(-0.0098{\times}N_{WBC})}$ with input velocity of 15 m/s. In addition, the determination coefficient is 0.915, which is sufficiently high.

• Childhood Kidney Diseases
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• v.22 no.2
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• pp.42-46
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• 2018

Purpose: We investigated whether the white blood cell (WBC) count to hemoglobin (Hgb) level ratio is correlated with the presence of cortical defects on dimercaptosuccinic acid (DMSA) renal scan in children with febrile urinary tract infection (UTI). Methods: We examined 95 children who were consecutively admitted to our hospital with their first episode of febrile UTI. Blood tests (C-reactive protein [CRP], WBC, Hgb] were performed. All enrolled children underwent DMSA scanning during admission. Data were compared between children with positive and negative DMSA results. The correlations between WBC to Hgb ratio and the presence of cortical defects on DMSA scan, and between WBC to Hgb ratio and CRP level were analyzed using the Pearson chi-squared test. Multiple logistic regression analysis was used to evaluate whether WBC to Hgb ratio could predict the cortical defects on DMSA scan in children with febrile UTI. Results: The WBC to Hgb ratio was significantly higher in children with positive DMSA results than in those with negative DMSA results; positively correlated with the presence of cortical defects on DMSA scan and CRP; and was a significant factor for predicting the presence of cortical defects on DMSA scan. Conclusion: The WBC to Hgb ratio may predict the presence of cortical defects on acute DMSA scans in children with febrile UTI.

• YAKHAK HOEJI
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• v.40 no.2
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• pp.230-237
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• 1996

The fractions of Epimedii Herba were examined for the immunological effects in ICR mice. Mice were divided into 4 groups and administered orally the fractions of Epimedii Herba for 10 days. The results of this study were summarized as following: (1) The fraction 1 (EtOAc layer) administered group as compared with control group significantly decreased spleen weight, Arthus reaction and hemagglutination (HA) titer but significantly increased circulating white blood cells (WBC). (2) The fraction 2 ($H_20$ layer) administered group as compared with control group significantly decreased liver weight, Arthus reaction and HA titer but significantly increased WBC. (3) The fraction 3 (ppt) administered group as compared with control group significantly increased liver weight, thymus weight rate, delayed type hypersensitivity, phagocytic activity and WBC. The results showed that Frs. 1 and 2 administered groups reduced humoral immune response but increased WBC, and that Fr. 3 administered group increased cell-mediated immune response, phagocytic activity and WBC.

• Journal of Environmental Health Sciences
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• v.1 no.1
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• pp.5-8
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• 1974

A survey was carried out in order to figure out of phenomenon of increasing and decreasing rate of WBC during a day in normal and healthy person from Oct. 1, 1972 to Nov. 31, 1972. For this survey, it was classified by two groups 50 male students and 35 female students who are from 18 to 25 years old. The blood sampling was collected by thin smear method 8 times from 7:30 A.M. to 10:30 P.M. by 2 hours intervals and calculated by direct manual method. As the results of this survey, the following conclusions were obtained 1) Number of WBC was the lowest degree during the forenoon, and it was the highest degree around the midnight. It was increase from around the noon up to the midnight and decrease from the midnight up to around the noon. 2) Increasing and decreasing curve of WBC of male and female was keeping same pace with both sex in a day. 3) Increase and decrease of lymphocyte and eosinophil was keeping almost same pace with WBC. 4) Increasing rate of number of monocyte was more speedily increasing during the afternoon than the night.

• Biomedical Science Letters
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• v.24 no.4
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• pp.334-340
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• 2018

The cytoplasmic elicitor, nucleotide-binding domain and leucine-rich repeat containing domain receptors (NLRs) is well established molecules in its role in inflammatory response. Among 22 NLR receptors, NOD2 is one of the intensively studied genes of elucidating for the inflammatory bowel disease and Crohn's disease as well. Recent research have accumulated that common genetic mutations in Parkinson's disease (PD) are increasingly related to the susceptibility to Crohn's disease. In this study, with the Korean Genome and Epidemiology Study, we aimed to perform the association between NOD2 polymorphisms and blood cell counts [WBC (white blood cell) count, RBC (red blood cell) count, platelet count], which linked supposedly to cytoplasmic inflammatory responses with clinical specialty. Linear regression analyses were performed, controlling for residential area, sex, and age as covariates. As a results, 12 SNPs from NOD2 gene were significantly associated with WBC counts (Bonferroni correction P-value criteria < 0.05/23=0.00218). In this study, we could ensure an association with NOD2 gene and WBC counts. This is the first report to have relationship between SNPs of NOD2 gene and WBC counts.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.29 no.7
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• pp.366-372
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• 2017

The objective of this study was to characterize Waveguide-Blow-Cutoff (WBC) array for Electromagnetic Pulse (EMP) shield in air duct or water pipe, the typical pathway of pulse in indoor space with critical electronic device. A numerical investigation with three different WBC designs (circular, rectangular, and hexagonal or honeycomb) was conducted to satisfy recommended shielding effectiveness (SE) levels from 80 dB to 140 dB. Pressure drop between upstream and downstream of EMP shields based on WBC arrays was also investigated to understand air flow feature in air duct of HVAC system. Results showed that honeycomb geometry outperformed other shapes in terms of reducing the depth of EMP shield, thus providing better air flow in duct path with lower local loss coefficient in HVAC system under SE requirements.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.19 no.2
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• pp.59-70
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• 2006

Objective : This study was performed to investigate the Anti-Inflammatory Effects of WooBangHaeGiTang on the Allergic Contact dermatitis. Method : Contact hypersensitivity assay, video microscope, WBC count, RBU count, neutrophil ratio, lymphpcyte ratio and GOT & GPT were measurd. Result : 1. At Contact hypersensitivity Aasay, at 24 hours after Control group & Sample group showed appreciably more ear swelling than Normal group, at 48 hours after Control group showed more ear swelling than Normal group & Sample group, at 72 hours after Control group & Sample group showed more ear swelling than Normal group 2. Regarding the number of WBC, at 24 or 48 hours after There are no significant difference among Normal group, Control group. Sample group, at 72 hours after Sample group showed more WBC than Control group. 3. Regarding the number of RBC, at 24 hours after Control group showed more RBC than Normal group, at 48 hours after Control group & Sample group showed more RBC than Normal group. at 72 hours after Control group showed more RBC than Normal group. 4. Regarding the percentage of neutrophil in WBC, at 24 & 48 hours after Control group & Sample group showed higher percentage than Normal group. 5. Regarding the percentage of Lymphocyte in WBC, at 24 hours after Sample group showed lower percentage than Normal group, at 48 hours after Sample group & Control group showed lower percentage than Normal group. 6. Regarding the GOT & GPT in blood, the GOT & GPT are in Normal scale, so there are no Hepatotoxicity in Normal group, Control group, Sample group. Conclusions : According to above experiments, WooBangHaeGiTang have some anti allergy effects on allergic contact dermatitis.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.6
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• pp.1164-1169
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• 2002

The purpose of this study was to examine the correlation of chronic prostatitis with sexual dysfunction and WBC counts on expressed prostatic secretion(EPS) with symptoms of sexual dysfunction. From 2001. 9. 1 to 2002. 3. 31, chronic prostatitis patients(30 examples) treated for more than 4 weeks were compared with normal group(30 examples) about hypoactive sexual desire disorder, erectile dysfunction, orgasmic disorder and hematospermia. We investigated sexual dysfunction according to the degree of prostatitis, improvement rate of prostatitis and sexual dysfunction. Chronic prostatitis patients compared with normal group were increased significantly in decreased libido(73.3%), erectile dysfunction(51.1%), orgasmic disorder(48.7%) and hematospermia(16.7%). In WBC very many/HPF group compared with others. though sexual dysfunction was highly revealed, but there was no statistic significance. In improvement rate of prostatitis, total improvement rate was 76.7%, WBC 10-30/HPF group 77.8%, WBC many/HPF group 72.8% and WBC very many/HPF group 80%. But the medical cure effect was the highest in WBC 10-30/HPF group. In the improvement rate of sexual dysfunction, total improvement rate was 68.5%, hematospermia 100%, decreased libido 90.9%, erectile dysfunction 67.4% and orgasmic disorder 60.3%. As a result of considering the relation with improvement rate of prostatitis and sexual dysfunction, there was a statistical significance at the erectile dysfunction. orgasmic disorder. The results showed the chronic prostatitis had effects on sexual dysfunction but there was no correlation between the degree of chronic prostatitis with sexual dysfunction. It also showed that the treatment of prostatitis had effects on improvements of erectile dysfunction and orgasmic disorder.