• Title/Summary/Keyword: WAS-2

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Synthesis of 6-amino-2-N-(n-propionylamino)selenazolo[4,5-f]indan (6-Amino-2-N-(n-propionylamino)selenazolo[4,5-f]indan의 합성)

  • Kim, Min-Kyeom;Ma, Eun-Sook
    • YAKHAK HOEJI
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    • v.52 no.1
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    • pp.20-26
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    • 2008
  • 2-Aminothiazole ring as a bioisoster of catechol in dopamine has provided with good oral availability and lipophilic property. Selenium was reported to have an improved antioxidant ability and to reduce the loss of dopamine. 2-Aminoindan, is a rigid form of dopamine, was evaluated as a dopamine agonist with low neurotoxocity. In order to develop a novel dopamine agonist, we tried to synthesize the selenazoloaminoindan derivative that is a hybrid structure of aminoindan and aminoselenazole instead of aminothiazole. 2-Indanone-2-oxime was reduced with $TiCl_4$ and $NaBH_4$ to form 2-aminoindan, which was reacted with propionyl chloride to give 2-N-n-propionylaminoindan (2). Compound 2 was reduced with $TiCl_4$ and $NaBH_4$ to afford 2-N-n-propylaminoindan (3) and it was nitrated and reduced to form 5-amino-2-N-n-propylaminoindan (5), which was reacted with KSeCN, $Br_2$, and glacial acetic acid to give 4,6-dibromo-5- amino-2-N-n-propylaminoindan (7) instead of selenazole ring formation. Otherwise, compound 2 was nitrated and hydrogenated to form 5-amino-2-N-n-propionylaminoindan (9), which was treated with KSeCN, $Br_2$, and glacial acetic acid to give 4,6-dibromo-5-amino-2-N-n-propionylaminoindan (10). Compound 9 was cyc1ized with KSeCN and glacial acetic acid in the absence of $Br_2$ to give 6-amino-2-N-(n-propionylamino)selenazolo[4,5-f]indan (11).

A Study of Abnormal Refraction Eye on Female Old Age (노인 여성의 굴절이상 눈에 대한 연구)

  • Kim, Douk-Hoon
    • Journal of Korean Ophthalmic Optics Society
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    • v.5 no.1
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    • pp.125-129
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    • 2000
  • To fine understand the visual acuity of female old age. This study was researched the visual acuity test by the object and subject methods. The major findings was as follows: 1. The eye types were 80.94% positive for hyperopia. 13.86% for myopia and 5.19% for emmetropia respectively. 2. The anbormal refraction eye was positive for mixed astigmatism for 78.27%, myoptic com pound astigmatism (10.99%), simple presbyopia(4.97%), myopic simple astigmatism(2.88%), presbyopia compound astigmatism (1.57%), simple myopia(0.78%) and presbyopia simple astigmatism(0.52%). 3. The axis of astigmatism was 60.23% for against regular astigmatism. 22.73% for oblique astigmatism and 17.05% for regular astigmatism respectively. 4. On the total myopic spheric power, the -0.50 spheric equivalent ${\leq}-2.00$ was 90.2%, the -2.00${\leq}-6.00$ was 9.8%. 5. On the total presbyopic spheric power, the -0.50${\leq}-2.00$ was 80.252%, the -2.00${\leq}-6.00$ was 16.99% and 2.56% for anything over the 6.00 diopter. 6. On the astigmatic power, the $0.50{\geq}$ cylinder power${\geq}1.00$ was 69.35%,the 1.00> cylinder power ${\geq}2.00$ was 27.38%, and anything over the 2.00 cylinder diopter was 3.27%.

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Effect of Degradative Products on Dibenzothiophene Desulfurization Activity of Gordona sp. MS6 (Gordona sp. MS6균주의 dibenzothiophene 탈황능에 미치는 분해산물의 영향)

  • 조경숙
    • Korean Journal of Environmental Biology
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    • v.18 no.1
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    • pp.33-39
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    • 2000
  • Gordona sp. MS6, desulfurizing petroleum, can convert dibenzothiophene (DBT) to 2-hydroxybiphenyl (2-HBP) and sulfate. In this study, the effect of DBT degradation product on DBT desulfurization activity was investigated. When $Na_2$SO$_4$ and DBT were simultaneously added in the medium sulfur sources, specific growth rate of strain MS6 was doubled compared to not adding $Na_2$SO$_4$. But, sulfate inhibited DBT desulfurization rate, furthermore, when 0.05 g/L $Na_2$SO$_4$ was supplied DBT desulfurization rate decreased down to 40%. When 2-HBP and its derivative, 2, 2'-dihydroxybiphenyl (DHBP) were not added, DBT desulfurization rate was 5.0 $\mu$mol L$^{-1}$ㆍh$^{-1}$. With the increase of 2-HBP and DHBP concentration, DBT desulfurization rate was decreased. No DBT desulfurization activity of Gordona sp. MS6 was observed when initial concentration was over 0.15 mM 2-HBP and 0.8 mM DHBP [Gordona sp., Desulfurization, Dibenzothiophene, 2-Hydroxybiphenyl, Sulfate].

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A Study on the Ceria Stabilized Tetragonal Zirconia Polycrystals(Ce-TZP)(I) : Effect of CeO2 Content on the Mechanical Properties and Fracture Behavior of Ce-TZP (CeO2 안정화 정방정 Zirconia 다결정체(Ce-TZP)에 관한 연구(I) : CeO2 함량에 따른 Ce-TZP의 기계적 성질과 파괴거동의 변화)

  • 김문일;박정현;강대석;문성환
    • Journal of the Korean Ceramic Society
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    • v.26 no.5
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    • pp.719-727
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    • 1989
  • By using commercial zirconia powder CeO2-ZrO2 ceramics containing 8~16mol% CeO2 was made by heat treatment at 1350~155$0^{\circ}C$ for 1~10hr. The minimum amount of CeO2 for obtaining complete tetragonal phase was 12mol%, and in the tetragonal phase region fracture toughness of Ce-TZP was decreased with increasing CeO2 content and the maximum value was obtained when 12mol% CeO2 was added. The bending strength goes through maximum at 14mol% CeO2. Fracture mode of Ce-TZP transformed from intergranular to transgranular fracture with increasing CeO2 content, so the morphology of fracture surface of 16mol% Ce-TZP was wholly transgranular and this tendency was independent on grain size. The crystal structure of the 12mol% Ce-TZP was monoclinic with fringes along the grain boundaries which are lying in the particular plane from the TEM observation. The chemical composition of the sintered body was homogeneous as a whole and some amorphism or air pocket was observed at the triple junction.

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Growth, Nitrogen Metabolism, and Nodulation of Hypernodulating Soybean Mutant Affected by Soil Fertility

  • Ha, Bo-Keun;Lee, Suk-Ha
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.46 no.2
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    • pp.145-149
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    • 2001
  • This study was performed to evaluate the growth and nodulation characters of hypernodulating soy-bean mutant, SS2-2, and to know the growth and yield performance of the mutant in infertile soil. Soil fertility was adjusted by mixing the different ratios of soil components including clay, river sand, and horticultural bed, which resulted in fertile and infertile soil. Dry weight, nitrogen concentration, and leaf nitrate reductase of each plant were measured around V6 stage (47 days after planting) and around R3 stage (82 days after planting). There were significant effects of soil fertility and soybean genotype on the total dry weights including root, nodule, stem, leaf, and pod dry weight at V6 and R3 stages. Total dry weight of hypernodulating mutant, SS2-2, was clearly less than that of its wild type, Sinpaldalkong 2. However, nodule development on the roots of SS2-2 was much greater than that of Sinpaldalkong 2, regardless of soil fertility. Though SS2-2 was smaller in plant size than Sinpaldalkong 2, genotypic difference in total nitrogen content was not significant at both V6 and R3 stages because SS2-2 fixed more nitrogen biologically than its wild type in the root nodule. The SS2-2 mutant showed lower plant yield in both infertile and fertile soil. The SS2-2 contained more crude seed protein than Sinpaldalkong 2, and was characterized with reduced top and root growth.

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Effect of $SO_3$ on Calciumsilicate Formation(III) (Calciumsilicate의 생성반응에 미치는 $SO_3$ 영향(III))

  • 임은극;박병철
    • Journal of the Korean Ceramic Society
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    • v.21 no.3
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    • pp.221-230
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    • 1984
  • In this study an investigation was made to determine optimum ratio between $SO_3$, MgO and $K_2O$ that maximizes $C_2S$ formation in Clinkering reaction Using response surface analysis method. It was proved that 1) Residual $K_2O$ int he clinker should be converted to $K_2SO_4$ because $K_2SO_4$ has less effect on the burnability than $K_2O$, 2) Optimum ratio if $SO_3$/K2O is 1.5, 3) Optimun balance between $CaSO_4$ and MgO is to be adjusted to such a level that w/o SO3=0.7(w/o MgO-2).4) In case of lack of $K_2O$ free CaO was minimized when $K_2SO_4$=2.3w/o and MgO=1.5w/o but if remaining $K_2O$ was 2w/o free CaI was minimized in the level that $K_2SO_4$=2.3w/o and MgO =1.5 w/o but if remaining $K_2O$ was 2 w/o free CaO was minimized in the level that $K_2SO_4$=4.5w/o and MgO =3.0 w/o.

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High Frequency Dielectric Properties of $CaF_2$ filled Glass-Composites ($CaF_2$가 Filler로 첨가된 유리복합체의 고주파 유전특성)

  • Kim, Sun-Young;Lee, Kyoung-Ho;Kim, Sung-Won
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2003.05c
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    • pp.277-281
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    • 2003
  • Effects of $CaF_2$ addition as a filler on the high frequency dielectric properties and sintering of CaO-$Al_2O_3-SiO_2-B_2O_3$(CASB) and ZnO-MgO-$B_2O_3-SiO_2$(ZMBS) glass composites were investigated. The optimal glass composition in the CASB system was 33.0CaO-$17.0Al_2O_3-35.0SiO_2-15.0B_O_3$(in wt%). The corresponding dielectric properties were k=8.1 and $Q{\times}fo$=1,200GHz. The sintering temperature was $800{\mu}m$. In case of 2MBS system, 25.0ZnO-25.0MgO-20.0$B_2O_3-30.0SiO_2$(in wt%) glass showed k=6.8 and $Q{\times}fo$=5,200GHz when it was sintered at $750^{\circ}C$. The maximum amount of $CaF_2$ in the CASB and 2MBS glass system without any detrimental effect on the sintering was 25.0 v/o and 15.0 v/o, respectively. The addition of $CaF_2$ in the glass systems improved the high frequency dielectric properties. In case of CASB+$CaF_2$ composite, k was 7.1 and $Q{\times}fo$ was 2,300GHz. And in case of 2MBS+$CaF_2$ composite, k was 5.9 and $Q{\times}fo$ was 8,100GHz. $CaF_2$ addition also reduced sintering temperature. Effects of $CaF_2$ on the dielectric and sintering properties was analyzed in terms of viscosity and crystallization behavior changes due to the interaction between $CaF_2$ and the glass systems.

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Hydrothermal Precipitation of PZT Powder (PZT분말의 수열합성에 관한 연구)

  • 이경희;이병하;대문정기;천하희흥지;강원호;박한수
    • Journal of the Korean Ceramic Society
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    • v.24 no.4
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    • pp.397-403
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    • 1987
  • Pb(Zr0.52Ti0.48)O3 powders were prepared by hydrothermal synthesis. Using soluble salts such as Pb(NO3)2, TiCl4 and ZrOCl2$.$8H2O and oxide such as PbO and TiO2 as starting materials, PZT powder was hydrothermally synthesized at the temperature range between 150$^{\circ}C$ and 200$^{\circ}C$. The result showed that reactivity by alkali was decreased in the sequence of Pb(NO3)2, TiCl4, ZrOCl2, PbO, TiO2 and ZrO2. Using the first three soluble salts, PZT powder was synthesiged at 150$^{\circ}C$ for 1hr. In PbO-TiCl4-ZrOCl2 system, PZT powder was synthesized at 150$^{\circ}C$ for 8rs. In Pb(NO3)2-TiO2-ZrOCl2 system, PZT powder was synthesized at 150$^{\circ}C$ for 16hrs, in PbO-TiO2-ZrOCl2 system, the powder was synthesized at 200$^{\circ}C$ for 8hrs.

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Selection of Legume Crop by Intercropping with Sorghum $\times$ Sudangrass Hybrid (Sorghum $\times$ Sudangrass 교잡종과 간작에 의한 청예 두과작물 선발)

  • 이상무;전병태
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.16 no.2
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    • pp.93-104
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    • 1996
  • A field experiment was conducted in Chungju and Jungwon to evaluate growth characteristics, dry matter yield, protein yield and palatability of intercropping comparing with monocropping forage crops by the use of sorghum $\times$ sudangrass hybrid(S.S.H.), five forage soybeans and two forage cowpeas of superior to selected experiment of varieties. All eight treatment plots were replicated three times and cutting date were cut July 6 and September 9. 1. The mean leaf number of S.S.H. in intercropping T2 treatment showed high compared to T1 treatment in all treatment except for Hwangkeum treatment, but T3 treatment was lower than the other treatments. In the leaf number of soybean, Jangbaek treatment was the highest as 47 leaves per plant, cowpea treatments showed high above 50 leaves. The stem diameter of S.S.H. in Jangyeob treatment of T2 treatment was 9.6mm. In legume, cowpea of T3 treatment was high as ranged from 7.9mm to 8.2mm. In stem hardiness of S.S.H., TI treatment was the lower than the other treatments, while Jangbaek treatment of T2 treatment was the highest as $2.0kg/cm^2$. In legume crops, Jangbaek and Baekun treatment were the highest as $1.6kg/cm^2$, but T3 treatment was very low as $0.3~0.6kg/cm^2$. 2. In the mean leaf ratio of S.S.H., T1 treatment was higher than T2 and T3 treatment as 34.9%. In the legume crops, Togyu treatment was the highest as 40.9%. In the mean tiller number of S.S.H., T2 treatment showed high compared to TI treatment, but T3 treatment of was rather decrease than The tiller number of S.S.H. in Jangyeob treatment of T2 treatment was the highest as 4.6 per plant. The dead stubble of S.S.H. was high in order to T3>T1>T2 treatment>, T3 treatment was highly about 2 times compared to T2 treatment. 3. S.S.H. as T3 treatment was resistant to lodging, but T3 and T1 treatment showed highly lodging. In the legums, T3 treatment was resistant to lodging, but T2 treatment showed highly lodging. In the S.S.H. of T2 treatment, the leaf of summer depression was not occurrence, but T3 treatment was higher than the other treatments. 4. The palatability of domestic animals was high in order of T2>Tl>T3, especially Togyu treatment of T2 treatment was the highest at the holstein and deer, and Jangyeob treatment of T2 treatment was the highest in the Korean native cattle. But T3 treatment was lower than other treatments in the holstein and Korean native cattle. 5. Fresh yield of monocropping(T1) was the highest as 94, 650kg/ha, while dry matter yield in Jangyeob treatment of T2 treatment was the highest as 15, 575/ha But fresh yield and dry matter yield of T3 treatment were the lowest(P<0.05). 6. Protein yield in T2 treatment was high, especially Jangyeob treatment of T2 treatment was the highest as 1, 605.5 kg/ha T3 treatment was low in spite of high protein content, because dry matter yield was lower than the other treatments. In conclusion, among T1, T2 and T3 treatment, Jangyeob, Togyu and Baekun treatments of T2 treatment showed optimum varieties for intercropping with S.S.H., because they showed high Dry matter yield, protein yield and palatability.

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A Study on the Content of Total Mercury in the Head Hair of Dental Personnel (치과계 종사자의 두발중 총 수은 함량에 관한 연구)

  • 이택승;손동헌
    • YAKHAK HOEJI
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    • v.23 no.1
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    • pp.17-29
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    • 1979
  • The total mercury content in the head hair of 87 dental personnel and 210 Seoul citizens as control was determined. 1) The mean value of mercury content in dentists (8.57ppm) was 3.3 times of Seoul male citizens (2.57ppm) and the median of the former (5.92 ppm) was higher than that of the latter (2.39ppm) by approximately 2.5 times. 2) The mean value of mercury content in dental nurses (5.79ppm) was 2.8 times of Seoul female citizens(2.11ppm) and the median of the former(4.62ppm) was higher than that of the latter (1.86ppm) by approximately 2.5 times. 3) The mean value of mercury content in Seoul citizens was 2.29ppm and the median was 1.98ppm. 4) There was no correlationship between the mercury content in the head hair of dentists and the length of dental surgery experience or the frequency of amalgam fiillings per day. 5) The mercury content of Seoul citizens was higher in the male than in the female. 6) It appears more meaningful to employ median values than mean values when the environmental pollution is considered.

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