• 제목/요약/키워드: Vulnerable option

검색결과 18건 처리시간 0.025초

신생아 임상연구에서의 Good Clinical Practice (Good Clinical Practice in Neonatal Clinical Research)

  • 박민수
    • Neonatal Medicine
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    • 제15권2호
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    • pp.119-122
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    • 2008
  • Clinical research is a necessity, not an option, for developing better and new medicines and therapeutic modalities. But in the course of clinical research, there are rules and guidelines that should be followed to ensure the due respect for persons, beneficence, and justice for persons who voluntarily participate in the research as described in the Belmont Report. Good Clinical Practice (GCP) is an "international scientific and ethical quality standard for designing, conducting, recording, and reporting" clinical trials. The main purposes of GCP would be to protect rights, safety, and well-being of trial subjects, in compliance with the principles of Declaration of Helsinki, and to assure that the data obtained from clinical trials are credible. In order to achieve these, investigators must be fully aware of the meanings as well as actual procedures involved in the research and should make the best effort to comply with GCP. For those individuals who belong to vulnerable populations, such as neonates, in addition to the general principles of GCP, further measures to ensure added protection should be implemented. It is our duty to develop and provide better care through clinical research even for neonates. But in doing so, we have to make sure that the importance of protecting the rights, safety, and well-being of the subjects supersede the interests of science and society.

Lateral Supramalleolar Flap for Reconstruction of Soft Tissue Defect around the Ankle Joint

  • Han, Soo-Hong;Kim, Seong-Hui;Lee, Soon-Chul;Lee, Ho-Jae;Kim, Woo-Hyun;Bong, Sun-Tae;Song, Won-Tae
    • Archives of Reconstructive Microsurgery
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    • 제23권1호
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    • pp.13-17
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    • 2014
  • Purpose: Soft tissue defect on foot and ankle is vulnerable and requires a thin flap for improvement of aesthetic and functional results. Lateral supramalleolar flap is a simple and fast procedure, which can preserve and supply reliable constant blood flow, and causes fewer donor site complications. The authors reviewed our cases and report the clinical results. Materials and Methods: Ten cases of soft tissue defects on the lower leg, around the ankle were treated with lateral supramalleolar flap. There were seven males and three females with a mean age of 54.8 years. The mean size of flaps was $5.9{\times}6.3$ cm and the mean follow-up period was 23 months. Flap survival and postoperative complications were evaluated. Results: Nine flaps survived completely without loss of flap. There was one case of partial wound dehiscence requiring debridement and repair, and another case of necrotic flap change requiring partial bone resection and closure. All patients were capable of weight bearing ambulation at the last follow up. Conclusion: The authors suggest that the lateral supramalleolar flap could be a useful option for treatment of soft tissue defect around the ankle joint.

Analysis of Web Browser Security Configuration Options

  • Jillepalli, Ananth A.;de Leon, Daniel Conte;Steiner, Stuart;Alves-Foss, Jim
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제12권12호
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    • pp.6139-6160
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    • 2018
  • For ease of use and access, web browsers are now being used to access and modify sensitive data and systems including critical control systems. Due to their computational capabilities and network connectivity, browsers are vulnerable to several types of attacks, even when fully updated. Browsers are also the main target of phishing attacks. Many browser attacks, including phishing, could be prevented or mitigated by using site-, user-, and device-specific security configurations. However, we discovered that all major browsers expose disparate security configuration procedures, option names, values, and semantics. This results in an extremely hard to secure web browsing ecosystem. We analyzed more than a 1000 browser security configuration options in three major browsers and found that only 13 configuration options had syntactic and semantic similarity, while 4 configuration options had semantic similarity, but not syntactic similarity. We: a) describe the results of our in-depth analysis of browser security configuration options; b) demonstrate the complexity of policy-based configuration of web browsers; c) describe a knowledge-based solution that would enable organizations to implement highly-granular and policy-level secure configurations for their information and operational technology browsing infrastructures at the enterprise scale; and d) argue for necessity of developing a common language and semantics for web browser configurations.

Fragility reduction using passive response modification in a Consequence-Based Engineering (CBE) framework

  • Duenas-Osorio, Leonardo;Park, Joonam;Towashiraporn, Peeranan;Goodno, Barry J.;Frost, David;Craig, James I.;Bostrom, Ann
    • Structural Engineering and Mechanics
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    • 제17권3_4호
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    • pp.527-537
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    • 2004
  • Consequence-Based Engineering (CBE) is a new paradigm proposed by the Mid-America Earthquake Center (MAE) to guide evaluation and rehabilitation of building structures and networks in areas of low probability - high consequence earthquakes such as the central region of the U.S. The principal objective of CBE is to minimize consequences by prescribing appropriate intervention procedures for a broad range of structures and systems, in consultation with key decision makers. One possible intervention option for rehabilitating unreinforced masonry (URM) buildings, widely used for essential facilities in Mid-America, is passive energy dissipation (PED). After the CBE process is described, its application in the rehabilitation of vulnerable URM building construction in Mid-America is illustrated through the use of PED devices attached to flexible timber floor diaphragms. It is shown that PED's can be applied to URM buildings in situations where floor diaphragm flexibility can be controlled to reduce both out-of-plane and in-plane wall responses and damage. Reductions as high as 48% in roof displacement and acceleration can be achieved as demonstrated in studies reported below.

보안 기능을 지원하는 TELNET 프로토콜의 설계 및 구현 (Design and implementation of TELNET protocol supporting security functionalities)

  • 성정기;서혜인;김은기
    • 한국정보통신학회논문지
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    • 제20권4호
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    • pp.769-776
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    • 2016
  • TELNET은 보안을 고려하지 않고 설계된 프로토콜이므로 네트워크 공격에 매우 취약하다. 이 문제를 해결하기 위한 방법으로 SSL/TLS와 SSH가 사용된다. 하지만 이 방법들은 추가적인 보안 프로토콜이 필요하고, 또한 기존의 TELNET과의 하위 호환성을 갖지 않는다. 본 논문에서는 내부적으로 보안 기능을 지원하여 기존의 TELNET과의 하위 호환성을 가지는 STELNET(Secured Telnet)을 제안하였다. STELNET은 옵션 협상을 통해 기존 TELNET과의 하위 호환성을 지원한다. STELNET에서 클라이언트는 ECDSA로 생성된 인증서와 전자서명으로 서버를 인증한다. 서버가 인증되면 두 호스트는 ECDH 알고리즘으로 세션 키를 생성하고, 이 세션 키를 사용하여 데이터를 AES로 암호화하며 SHA-256으로 HMAC을 생성한다. 이후 암호화된 데이터와 HMAC을 전송한다. 결과적으로 기존 TELNET과 하위 호환성을 가지는 STELNET은 중간자 공격을 방어하고 전송되는 데이터의 기밀성과 무결성을 보장하는 보안 기능을 지원한다.

The Great Saphenous Vein-An Underrated Recipient Vein in Free Flap Plasty for Lower Extremity Reconstruction: A Retrospective Monocenter Study

  • Meiwandi, Abdulwares;Kamper, Lars;Kuenzlen, Lara;Rieger, Ulrich M.;Bozkurt, Ahmet
    • Archives of Plastic Surgery
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    • 제49권5호
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    • pp.683-688
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    • 2022
  • Background Reconstruction of large soft tissue defects of the lower extremity often requires the use of free flaps. The main limiting factor and potential for complications lie in the selection of proper donor and recipient vessels for microvascular anastomosis. While the superficial veins of the lower leg are easier to dissect, they are thought to be more vulnerable to trauma and lead to a higher complication rate when using them instead of the deep accompanying veins as recipient vessels. No clear evidence exists that proves this concept. Methods We retrospectively studied the outcomes of 97 patients who underwent free flap plasty to reconstruct predominantly traumatic defects of the lower extremity at our institute. The most used flap was the gracilis muscle flap. We divided the population into three groups based on the recipient veins that were used for microvascular anastomosis and compared their outcomes. The primary outcome was the major complication rate. Results Overall flap survivability was 93.81%. The complication rates were not higher when using the great saphenous vein as a recipient vessel when comparing to utilizing the deep concomitant veins alone or the great saphenous vein in combination to the concomitant veins. Conclusions In free flap surgery of the lower extremity, the selection of the recipient veins should not be restricted to the deep accompanying veins of the main vessels. The superficial veins, especially the great saphenous vein, offer an underrated option when performing free flap reconstruction.

보호출산제 시행과 젠더 및 보건의료 이슈 (Gender and healthcare issues related to the Protected Birth Act in Korea)

  • 정지아
    • 여성건강간호학회지
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    • 제30권2호
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    • pp.101-106
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    • 2024
  • This paper discusses the implications of the birth notification system and the Protected Birth Act in Korea. Aiming to prevent infanticide and abandonment of infants, the law will enter into force on July 19, 2024 in South Korea. The birth notification system mandates that both parents and the head of the medical institution where the birth occurred must report the event. In parallel, the Protected Birth Act will be implemented, allowing pregnant women in crisis who wish to remain anonymous, the option to give birth outside of a hospital setting in a way that safeguards the life and health of the child. However, many issues are being raised in Korean society in advance of the implementation of the Protected Birth Act. There is widespread concern that the Protected Birth Act fails to protect either women or children, especially as it raises issues regarding the need for legislation to protect children with disabilities and to address gaps for migrant women and children. This paper examines the gender and healthcare issues relating to the Protected Birth Act, focusing on women's health and human rights. The Act continues to perpetuate discrimination against out-of-wedlock pregnancies and upholds the ideology of the traditional family model. Furthermore, the legislative process did not address protective measures for the various reasons behind child abandonment. Critical issues such as women's autonomy, safe pregnancy termination, and paternal responsibility in childbirth are also notably absent. However, with the Act set to take effect soon, it is crucial for healthcare providers to comprehend the rationale and procedures associated with birth notification and the Protected Birth Act, and to prepare for its nationwide implementation. The law defines the socially vulnerable as its main beneficiaries, and it is necessary to strengthen social safety nets to improve their access to healthcare, eliminate prejudice and discrimination against out-of-wedlock pregnancies, and embrace the diversity of our society. We eagerly anticipate future discussions on gender and healthcare issues, as well as amendments to the law that reflect real-world circumstances to provide genuine protection for pregnant women in crisis and their infants.

국회 외곽 경호·경비시스템 발전방향에 관한 연구 (Improving the Protection and Security System Outside the National Assembly Building)

  • 최오호
    • 시큐리티연구
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    • 제60호
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    • pp.113-135
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    • 2019
  • 대한민국 국회는 "가"급 국가중요시설임에도 불구하고 테러 발생에 대한 가능성과 국회 청사내 집회 및 시위와 금지물품 반입은 점점 증가하고 있으며, 열린국회를 지향함으로써 많은 출입문 개방과 다수의 이용자로 인해 출입통제에 있어 취약점이 많다고 할 수 있다. 또한, 국회를 공격함으로써 얻게 되는 상징적인 효과는 매우 높지만 보안관리 수준은 상대적으로 매우 낮아 테러 공격의 대상이 될 가능성이 매우 높다. 이러한 보안상의 취약점을 해결하기 위해서는 제3선인 외곽에서부터의 적절한 출입통제시스템을 운용해야 한다. 하지만 외곽에서 적절한 출입통제가 이루어지지 않고 있으며, 외곽 경비를 담당하고 있는 국회경비대는 2023년 의무경찰 폐지에 따라 2020년 6월에 철수할 예정이므로 이에 따른 외곽 경비 대체 방안과 더불어 외곽 경호·경호경비시스템을 강화할 수 있는 방안을 조속히 마련할 필요가 있다. 이에 따라 본 연구에서는 국회사무처 보안 분야 담당 공무원 114명을 대상으로 외곽 경호·경비시스템에 대한 인식조사를 실시하였다. 연구 결과 국회 외곽에서 위협상황이 발생할 가능성이 높다고 인식하고 있으며, 지능형 영상감지 시스템 및 침입탐지시스템과 드론 등 4차 산업혁명 기술 도입에 긍정적으로 인식하고 있다. 또한, 3선 경호 체계를 중장기적으로 일원화하고 전담부서를 설치하는 방안에 대해 긍정적으로 인식하고 있으며, 국회경비대 대체 방안으로는 청원경찰이 가장 높은 응답률을 보였고, 중장기적으로 의회경찰을 도입하는 것에 긍정적으로 인식하고 있다.