• 유기물자원화
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• 제23권2호
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• pp.28-35
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• 2015

본 연구에서는 학교 식당에서 배출되는 음식물류 폐기물을 준 회분식 액순환 건식 혐기성 소화를 이용해서 메탄가스를 생산하였다. 두 시스템이 운전되었는데, 각 시스템은 생물반응조와 액 저장조로 구성되었다. 각 생물반응조 바닥은 스크린이 설치되어 있어 2.5L의 분리된 액체는 액 저장조로 30분 동안 이송되고 이송이 끝나자마자 이송된 액은 반응조 상부로 투입된다. 이 같은 순환은 고농도의 VFAs를 가지는 액체를 반응조 상부로 공급하는 역할을 한다. 실험 초기에는 음식물류 폐기물/식종 미생물의 부피 비는 2:8이고 이는 9g VS/L의 유기물 부하로 나타낼 수 있다. 음식물류 폐기물 투입은 2주에 한번이었고, 평균 수분, 휘발물질, 회성분은 각각 65.91%, 32.73%과 1.36%로 파악되었다. 두 개의 고형물 부하가 연구되었는데, 각각 3.51g VS/d (System A)와 3.86g VS/d(System B)이다. 음식물류 폐기물 당 메탄 발생량은 각각 $6.30m^3CH_4/kgVS{\cdot}d$(System A)와 $4.94m^3CH_4/kgVS{\cdot}d$(System B)이다.

• Journal of Digestive Cancer Research
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• 제5권2호
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• pp.73-85
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• 2017

Background: To compare the quality of life (QoL), the convenience of chemotherapy and satisfaction between colon cancer patients treated with FOLFOX4 and XELOX. Methods: The study was conducted in 26 patients with stage III colon cancer. Patients were received FOLFOX4 (n=17) or XELOX (n=9). QoL, convenience, and satisfaction were assessed using the Quality of Life Questionnaire-C30 (QLQ-C30), Quality of Life Questionnaire-Chemotherapy Induced Peripheral neuropathy (QLQ-CIPN) and Functional Assessment of Chronic Illness Therapy Chemotherapy Convenience and Satisfaction Questionnaire (FACIT-CCSQ), respectively. Patients completed questionnaires at baseline, at cycle 4 (C4) and cycle 8 (C8) (FOLFOX4) or at cycle 3 (C3) and cycle 6 (C6) visits (XELOX) and at their final visit. Results: In the QLQ-C30, at the final visit, XELOX patients had better functional scores than FOLFOX4 patients (physical: 85.7 vs.60.4, p=0.03; role: 83.3 vs. 57.5, p=0.04) as well as better symptom scores (constipation: 9.5 vs. 40.4, p=0.01). In CIPN, at the C6/C8 visit, XELOX patients had lower motor scale scores than FOLFOX4 patients (3.8 vs. 21.6, p=0.02). Moreover, at the C6/C8 visit, XELOX was more convenient than FOLFOX4 in FACIT-CCSQ (79.7 vs. 55.5, p=0.04). Male patients were especially likely to consider XELOX to be more convenient (90.0 vs. 55.0, p=0.01) and satisfactory (55.4 vs. 26.2, p=0.03) and fewer concern (91.0 vs. 65.0, p=0.03) than FOLFOX4. XELOX patients spent fewer days on hospital visits at C3/C4, C6/C8 and final visit (2.8 vs. 4.2, p=0.01; 2.7 vs. 4.1, p=0.01; 3.0 vs. 4.5, p=0.01). Conclusion: XELOX may be a better adjuvant chemotherapy choice for patients with colon cancer than FOLFOX4 in terms of QoL, convenience, and satisfaction.

• Toxicological Research
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• 제30권3호
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• pp.179-184
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• 2014

Xenobiotics causing a variety of toxicity in biological systems could be classified as two types, inorganic and organic chemicals. It is estimated that the organic xenobiotics are responsible for approximately 80~90% of chemical-induced toxicity in human population. In the class for toxicology, we have encountered some difficulties in explaining the mechanisms of toxicity caused especially by organic chemicals. Here, a simple flowchart was introduced for explaining the mechanism of toxicity caused by organic xenobiotics, as the central dogma of molecular biology. This flowchart, referred to as a central dogma, was described based on a view of various aspects as follows: direct-acting chemicals vs. indirect-acting chemicals, cytochrome P450-dependent vs. cytochrome P450-independent biotransformation, reactive intermediates, reactivation, toxicokinetics vs. toxicodynamics, and reversibility vs. irreversibility. Thus, the primary objective of this flowchart is to help better understanding of the organic xenobiotics-induced toxic mechanisms, providing a major pathway for toxicity occurring in biological systems.

• 한국세라믹학회지
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• 제30권10호
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• pp.866-870
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• 1993

For VO2-based sensors applicable to temperature measurements and optical disk materials by the nature of semiconductor to metal transition, the crystallinity and temperature vs. resistance characteristics were investigated as a function of the heat treatment temperature. The bead-type sensors were prepared through typical sensor fabrication processing and heat-treated at 40$0^{\circ}C$, 50$0^{\circ}C$, and $600^{\circ}C$, respectively, for 30 minutes in H2 gas atmosphere. As results of the temperature vs. resistance measurements, the electrical resistance in the phase transition range was decreased by 102 order for the VO2 sensor and by 103 order for the V71P11Sra18 system. It was estimated that the hysteresis, temperature vs. resistance, and current vs. voltage characteristics of the V71P11Sr18 system could be utilized for commericialization as a temperature sensor.

• Journal of Gastric Cancer
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• 제21권3호
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• pp.246-257
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• 2021

Purpose: It is unclear whether high-definition (HD) imaging improves visibility and diagnostic ability in early gastric cancer (EGC) compared with standard-definition (SD) imaging. We aimed to compare the diagnostic performance and visibility scores of HD and SD ultraslim endoscopes in EGC. Materials and Methods: We used HD and SD ultraslim endoscopes to obtain 60 images with similar compositions of gastric environments. Of the 60 images, 30 showed EGC (15 images for each modality) and 30 showed no EGC (15 images for each modality). Seventeen endoscopists evaluated the presence and location of the lesions in each image. Diagnostic ability was compared between modalities. The color difference between a lesion and the surrounding mucosa (ΔE) was measured and compared between the modalities. Results: The ability of HD to detect EGC was significantly higher than that of SD (accuracy: 80.8% vs. 71.6%, P=0.017; sensitivity: 94.9% vs. 76.5%, P<0.001; positive predictive value, 76.2% vs. 55.3%, P<0.001; and negative predictive value (NPV), 94.1% vs. 73.5%, P<0.001). The ability of HD to determine the horizontal extent of EGC was significantly higher than that of SD (accuracy: 71.0% vs. 57.8%, P=0.004; sensitivity: 75.3% vs. 49.0%, P<0.001; NPV, 72.9% vs. 55.9%, P<0.001; and area under the curve: 0.891 vs. 0.631, P=0.038). The mean ΔE was significantly higher for HD than for SD (10.3 vs. 5.9, P=0.011). Conclusions: The HD ultraslim endoscope showed a higher diagnostic performance in EGC than the SD endoscope because it provided good color contrast.

• 한국환경과학회지
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• 제30권2호
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• pp.135-143
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• 2021

This study executed evaluation of drying characteristics based on the polymer injection rate (8%, 10% and 12%) and the drying method[NIF(near-infrared ray). According to this study analyzed VS, VS/TS, and calorific value compared with 'the auxiliary fuel standard of the thermoelectric power plant and the combined heat & power plant'. The results are as follows. In the case of NIR, the VS was slightly changed at the early stage of the material preheating period and the constant drying rate period with low moisture evaporation. But VS reduction was shown higher as moisture was dried. In the case of non-digested sludge with high VS content, the VS reduction rate by drying was shown lower than that of digested sludge. As the flocculant injection rate increased, the VS loss due th drying was found to be small. Also, the higher the flocculant injection rate was the longer the drying time. Especially, in the case of the NIR drying equipment, as the moisture content of sewage sludge decreased(moisture content 20~40%), the loss of net VS also showed a tendency to increase sharply. It is shown that the high calorific value according to the drying time of the non-digested sludge was changed from 590 kcaℓ/kg to 3,005 kcaℓ/kg and from 539 kcaℓ/kg to 2,796 kcaℓ/kg.

• 한국간담췌외과학회지
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• 제28권2호
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• pp.220-228
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• 2024

Backgrounds/Aims: Postoperative pancreatic fistula is the key worry in the ongoing debate about the safety and effectiveness of total laparoscopic pancreaticoduodenectomy (TLPD). Laparoscopic-assisted pancreaticoduodenectomy (LAPD), a hybrid approach combining laparoscopic resection and anastomosis with a small incision, is an alternative to TLPD. This study compares the short-term outcomes and oncological efficacy of LAPD vs. open pancreaticoduodenectomy (OPD). Methods: A retrospective analysis of data of all patients who underwent LAPD or OPD for periampullary carcinoma at a tertiary care center in Northeast India from July 2019 to August 2023 was done. A total of 30 LAPDs and 30 OPDs were compared after 1:1 propensity score matching. Demographic data, intraoperative and postoperative data (30 days), and pathological data were compared. Results: The study included a total of 93 patients, 30 underwent LAPD and 62 underwent OPD. After propensity score matching, the matched cohort included 30 patients in both groups. The LAPD presented several advantages over the OPD group, including a shorter incision length, reduced postoperative pain, earlier initiation of oral feeding, and shorter hospital stays. LAPD was not found to be inferior to OPD in terms of pancreatic fistula incidence (Grade B, 30.0% vs. 33.3%), achieving R0 resection (100% vs. 93.3%), and the number of lymph nodes harvested (12 vs. 14, p = 0.620). No significant differences in blood loss, short-term complications, pathological outcomes, readmissions, and early (30-day) mortality were observed between the two groups. Conclusions: LAPD has comparable safety, technical feasibility, and short-term oncological efficacy.

• 대한생식의학회:학술대회논문집
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• 대한불임학회 2002년도 제43차 추계학술대회
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• pp.23-30
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• 2002

• Asian-Australasian Journal of Animal Sciences
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• 제23권6호
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• pp.792-798
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• 2010

Four experiments with 2,020 nursery pigs (Triumph-4${\times}$PIC Camborough 22) were conducted at a commercial research site to evaluate the effects of including 30% distillers dried grain with solubles (DDGS) in late nursery diets on pig growth performance and to compare the effects of pelleted and meal diets containing 30% DDGS on growth performance and nutrient digestibility. In Exp. 1, 312 pigs (10.54${\pm}$0.16 kg) were allotted to two diets: corn-soybean meal based control diet and a corn-soybean meal diet containing 30% DDGS. In Exp. 2, 337 pigs (16.70${\pm}$0.14 kg) were used to validate Exp. 1 with similar diets. In Exp. 3, 665 pigs (11.77${\pm}$0.12 kg) were allotted to diets containing 30% DDGS, but in different forms: meal or pellet. Fecal samples were collected during the final day of the trials to measure nutrient and energy apparent total tract digestibility (ATTD). In Exp. 4, 706 pigs (18.40${\pm}$0.18 kg) were allotted to the same diets as Exp. 3. In Exp. 1 and 2, there was no (p>0.05) effect of DDGS on ADG, ADFI or G:F. In Exp. 3, pelleting improved (p<0.01) ADG (578 vs. 541 g/d) and G:F (714 vs. 674 g/kg), with no difference (p>0.05) in ADFI. The ATTD of most nutrients and energy were improved by pelleting (p<0.05). In Exp. 4, ADG (717 vs. 675 g/d) and G:F (680 vs. 648 g/kg) were improved by pelleting (p<0.01), with no difference (p>0.05) in ADFI. In conclusion, 10-23 kg pigs in late nursery phase can be fed up to 30% DDGS without having a detrimental effect on pig performance, and pelleting the diet will increase nutrient and energy availability.

• 한국임상약학회지
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• 제27권1호
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• pp.30-37
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• 2017

Background: We investigated the impact of financial compensation on patients' decision of participation in clinical trials and the related factors with patients' attitudes and considerations. Methods: A survey questionnaire was placed from October 31 to November 16, 2017 to the subjects who were enrolled in the trials of chronic diseases. Patients' socio-demographic characteristics were collected and the potential reasons for participating in the trials were assessed using 5-likert scores. Results: Sixty eight of 110 respondents (61.8%) indicated to participate clinical trials regardless of financial compensation. The differences were found between patients who were unwilling to participate without compensation and those who were willing to participate regardless of compensation in mean ages (43.9 years vs. 52.0 years, p<0.05), marital status (married, 47.6% vs 79.4%, p<0.01), religions (yes, 45.2% vs 67.6%, p<0.05) and monthly income (${\geq}3$ million won, 19.0% vs 45.6%, p<0.01). The potential reasons for participation in the trials between two groups were doctor's suggestion (52.4% vs. 77.9%, p<0.01), the expectation of health improvement (54.8% vs. 73.5%, p<0.05), the types and numbers of procedure (33.3% vs. 16.2%, p<0.05) and the duration of clinical trials (59.5% vs. 27.9%, p=0.001). In regression analysis, the monthly income of ${\geq}3$ million won (odd ratio, OR=3.221, p=0.026,) and the duration of trials (OR=0.290, p=0.017) were related to the group with the willingness to participate regardless of compensation. Conclusion: This stady showed that more than half of study subjects would participate in the clinical trials of chronic diseases regardless of financial compensation.