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Polysomnographic Results before and after Uvulopalatopharyngoplasty

  • Kim, Cheon-Sik;Kim, Dae-Sik;Lee, Yong-Seok;Cho, Cheon-Ung;Pae, Sang-Ho;Kim, Won-Tae
    • Korean Journal of Clinical Laboratory Science
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    • v.45 no.2
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    • pp.73-76
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    • 2013
  • Uvulopalatopharyngoplasty (UPPP) is one possibility for the treatment of Obstructive Sleep Apnea (OSA). The aim of this study was study the analysis of polysomnography of pre-UPPP and post-UPPP. All patients were evaluated by means of a physical examination, the epworth sleepiness scale (ESS), the beck depression inventory (BDI) and the nocturnal polysomnography (PSG) before surgery, and 6~12 months after surgery. A total of 15 patients were investigated. All underwent UPPP. The patients were between 26 and 62 years old ($mean{\pm}SD$; $39.7{\pm}10.9$) with a lean body mass index (BMI) of $mean{\pm}SD$; $26.2{\pm}3.0kg/m^2$. The comparison of sleep questionnaires showed that after UPPP, the patients had a significantly lower BMI ($26.2{\pm}3.0kg/m^2$ vs $26.0{\pm}3.4kg/m^2$, p=0.241), ESS ($10.0{\pm}5.4$ vs $6.9{\pm}3.2$, p=0.022), BDI ($9.2{\pm}8.2$ vs $4.2{\pm}4.3$, p=0.343) and higher blood pressure ($127.5{\pm}12.1$ vs $123.7{\pm}12.0$, p=0.272) compared to before UPPP. The comparison of sleep parameters showed that after UPPP, patients had a significantly lower stage N1 ($108.8{\pm}53.1$ vs $82.2{\pm}48.9$, p=0.016), lower sleep latency ($4.9{\pm}4.4$ vs $2.0{\pm}1.7$, p=0.083), a lower total arousal number ($210.6{\pm}90.3$ vs $147.1{\pm}87.3$, p=0.019), lower oxygen desaturation index (ODI) ($30.2{\pm}20.9$ vs $10.2{\pm}15.1$, p=0.006), lower apnea-hypopnea index (AHI) ($31.6{\pm}22.4$ vs $10.9{\pm}15.4$, p=0.005), and a lower respiratory disturbance index (RDI) ($37.4{\pm}21.3$ vs $18.5{\pm}16.5$, p=0.008) compared to after UPPP. The comparison of sleep parameters showed that after UPPP, patients had a significantly higher stage N2 ($154.0{\pm}39.9$ vs $180.5{\pm}49.5$, p=0.017), higher REM ($58.5{\pm}29.7$ vs $72.6{\pm}34.0$, p=0.249), higher $meanSaO_2$ ($94.3{\pm}2.0$ vs $95.9{\pm}0.9$, p=0.043), and higher $meanSaO_2$ ($79.3{\pm}8.5$ vs $83.1{\pm}7.9$, p=0.116) than before UPPP. After UPPP, 6 patients were cured, 2 showed marked improvement, and 7 did not improve. After surgery, the success of the treatment was at 53%. The subjective patient satisfaction was higher than before the surgery.

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Effect of Type of Culture Media on B6D2F1 Mice Oogenesis (배양액 종류가 B6D2F1 마우스 배아발생능력에 미치는 영향)

  • Yoo, Chang-Seok;Park, Kee Sang;Seo, Byoung Boo
    • Journal of Embryo Transfer
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    • v.31 no.1
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    • pp.19-25
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    • 2016
  • This study was conducted to evaluate the effects of type of culture media (BM, G2, OS, TCM, and MEM) on B6D2F1 mice oogenesis. In the present study, B6D2F1/CrljOri $F_1$ mice were utilized in order to maximize oogenesis. Also we used TCM-199, Dulbecco's medified Eagle's medium (DMEM), embryo culture medium (Fertilization medium, Cleavage medium, Blastocyst medium), G series medium and One step medium. In vitro maturation was highest in BM followed by the order of OS, MEM, TCM and G2 ($90{\pm}2.8%>88{\pm}3.2%>85{\pm}4.9%>78{\pm}10.2%>64{\pm}7.7%$, respectively). To note, the G2 group was statistically different compared to other groups (p<0.05). On the other hand the fertilization rate was highest in the G2 group followed by BM, OS, TCM, and MEM ($87{\pm}7.2%>85{\pm}6.9%>74{\pm}14.0%>71{\pm}13.8%>2{\pm}1.4%$, respectively). The MEM group was significantly lower compared to other groups (p<0.05). The developmental rate was highest in the OS group followed by the G2 group and the BM group albeit no statistical significance was noted ($73{\pm}11.6%>71{\pm}9.2%>66{\pm}10.4%$). Of note, all cells of the TCM and MEM groups were died during embryonic development. The zona hatched rate ($51{\pm}9.8%$ vs. $50{\pm}9.1%$ vs. $47{\pm}7.2%$ for BM, G2, and OS respectively) and attached rate ($45{\pm}12.3%$ vs. $38{\pm}16.1%$ vs. $37{\pm}11.5%$ for BM, G2, and OS respectively) were not different amongst groups. No difference was found in total cell numbers ($74{\pm}13.9$ vs. $64{\pm}9.2$ vs. $76{\pm}6.7$ for BM, G2, and OS respectively), ICM cell numbers ($20{\pm}1.9$ vs. $14{\pm}1.8$ vs. $15{\pm}2.1$), TE cell numbers ($55{\pm}12.5$ vs. $49{\pm}10.7$ vs. $61{\pm}5.9$), % ICM ($30{\pm}2.8%$ vs. $24{\pm}7.0%$ vs. $22.8{\pm}2.2%$) and ICM:TE ratio ($1:2{\pm}0.5$ vs. $1:3.1{\pm}0.8$ vs. $1:3.1{\pm}0.5$) amongst groups. In summary, these results can provide fundamental data to maximize culture condition for in vitro fertilization on B6D2F1 mice.

Comparison of Single-Incision Robotic Cholecystectomy, Single-Incision Laparoscopic Cholecystectomy and 3-Port Laparoscopic Cholecystectomy - Postoperative Pain, Cosmetic Outcome and Surgeon's Workload

  • Kim, Hyeong Seok;Han, Youngmin;Kang, Jae Seung;Lee, Doo-ho;Kim, Jae Ri;Kwon, Wooil;Kim, Sun-Whe;Jang, Jin-Young
    • Journal of Minimally Invasive Surgery
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    • v.21 no.4
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    • pp.168-176
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    • 2018
  • Purpose: Robotic-associated minimally invasive surgery is a novel method for overcoming some limitations of laparoscopic surgery. This study aimed to evaluate the outcomes (postoperative pain, cosmesis, surgeon's workload) of single-incision robotic cholecystectomy (SIRC) vs. single-incision laparoscopic cholecystectomy (SILC) vs. conventional three-port laparoscopic cholecystectomy (3PLC). Methods: 134 patients who underwent laparoscopic or robotic cholecystectomy at a single center during 2016~2017 were enrolled. Prospectively collected data included demographics, operative outcomes, questionnaire regarding pain and cosmesis, and NASA-Task Load Index (NASA-TLX) scores for surgeon's workload. Results: 55 patients underwent SIRC, 29 SILC, and 50 3PLC during the same period. 3PLC patient group was older than the others (SIRC vs. SILC vs. 3PLC: 48.1 vs. 42.2 vs. 54.1 years, p<0.001). Operative time was shortest with 3PLC (44.1 vs. 38.8 vs. 25.4 min, p<0.001). Estimated blood loss, postoperative complications, and postoperative stay were similar among the groups. Pain control was lowest in the 3PLC group (98.2% vs. 100% vs. 84.0%, p=0.004), however, at 2 weeks postoperatively there were no differences among the groups (p=0.374). Cosmesis scores were also worst after 3PLC (17.5 vs. 18.4 vs. 13.3, p<0.001). NASA-TLX score was highest in the SILC group (21.9 vs. 44.3 vs. 25.2, p<0.001). Conclusion: Although SIRC and SILC take longer than 3PLC, they produce superior cosmetic outcomes. Compared with SILC, SIRC is more ergonomic, lowering the surgeon's workload. Despite of higher cost, SIRC could be an alternative for treating gallbladder disease in selected patients.

Operation modes and Protection of VS(Vertical Stabilization) Converter for International Thermonuclear Experimental Reactor (국제 핵융합실험로용 VS(Vertical Stabilization) 컨버터의 운전모드 및 보호동작)

  • Jo, Hyunsik;Jo, Jongmin;Oh, Jong-Seok;Suh, Jae-Hak;Cha, Hanju
    • The Transactions of the Korean Institute of Power Electronics
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    • v.20 no.2
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    • pp.130-136
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    • 2015
  • This study describes the structure and operation modes of vertical stabilization (VS) converter for international thermonuclear experimental reactor (ITER) and proposes a protection method. ITER VS converter supplies voltage (${\pm}1000V$)/current (${\pm}22.5kA$) to superconducting magnets for plasma current vertical stabilization. A four-quadrant operation must be achieved without zero-current discontinuous section. The operation mode of the VS converter is separated in 12-pulse mode, 6-pulse mode and circulation current mode according to the magnitude of the load current. Protection measures, such as bypass and discharge, are proposed for abnormal conditions, such as over current, over voltage, short circuit, and voltage sag. VS converter output voltage is controlled to satisfy voltage response time within 20 msec. Bypass operation is completed within 60 msec and discharge operation is performed successfully. The feasibility of the proposed control algorithm and protection measure is verified by assembling a real controller and implementing a power system including the VS converter in RTDS for a hardware-in-loop (HIL) facility.

A Study on Conception of Friendship in Korean Children of School Age (학령기 아동의 우정관계 개념에 관한 연구)

  • Lee, Ju Ok
    • Korean Journal of Child Studies
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    • v.6 no.2
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    • pp.35-58
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    • 1985
  • The purpose of this study was to investigate the components in friendship as reported by Korean children of School age Specially, four major aspects of friendship - definition of friendship, friendship formation, friendship expectation, and friendship termination were explored. The subjects of this study consisted of 600 elementary school children in Grades 1 through 6, 50 males and 50 females at each grade level. Based on Bigelow (1977) five open - ended questions were administered. First and second graders were interviewed individually while 3rd-6th graders replied to a questionnaire in class. For content analysis, responses of each child were coded into 22 categories and each category was assigned a score from 1 to 4 according to its frequency. The data were analyzed by factor analysis. The results showed that four major aspects of friendship in Korean children of school age were found to consist of four different factors. DEFINITION OF FRIENDSHIP was found to consist of the factors; 1) reciprocity of liking vs. helping 2) global evaluation vs helping 3) sharing and 4) common activities. FRIENDSHIP FORMATION was found to consist of the factors; 1) situational effects vs complex evaluation 2) structural dimension vs common activities 3) helping and 4) staring. FRIENDSHIP EXPECTATION was found to consist of the factors; 1) mutuality 2) common activities vs. loyalty & commitment 3) exclusive - dyadic activities vs. admiration (character) and 4) interactive a1truism. FRIENDSHIP TERMINATION was found to consist of the factors; 1) physical separation vs disappointment (character) 2) conflict 3) physical separation vs. psychological dimension and 4) general altruism.

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Output Control of ITER Vertical Stabilization Converter with Circulating Current Technique (순환전류를 이용한 ITER Vertical Stabilization 컨버터의 출력 제어)

  • Chung, Gyo-Bum;Ji, Jun-Keun;Mok, Hyung-Soo
    • The Transactions of the Korean Institute of Power Electronics
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    • v.14 no.5
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    • pp.379-386
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    • 2009
  • This paper investigates the operation of ITER(International Thermonuclear Experimental Reactor) Vertical Stabilization(VS) converter with circulating current. The VS converter has two subunits in parallel. The subunit is composed two back-to-back 12 pulse thyristor converter in series. The circulating current free technique can not always maintain the closed path for the load current because of a dead time zone of the converter operation at the region of the load current inversion. The complex circulation current technique for the load current inversion with VS converter can achieve the fast response and always maintain the closed path for the load curret. The paper proposes the new circulating current algorithm for the load current inversion of ITER VS converter and proves the performance of the circulating current technique with PSIM simulation study.

Molecular screening of Feline bocaviruses (FBoVs) from captured wild felids in Korea

  • Yong-Gu Yeo;Jong-Min Kim;Hye-Ryung Kim;Jonghyun Park;Jung-Hoon Kwon;Oh-Deog Kwon;Choi-Kyu Park
    • Korean Journal of Veterinary Service
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    • v.47 no.1
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    • pp.41-48
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    • 2024
  • Feline bocavirus (FBoV) is considered an emerging pathogen recently identified in domestic cats worldwide. To date, three species of FBoVs (FBoV-1, FBoV-2, and FBoV-3) have been reported, but there are no reports identifying FBoVs in Korea. In this study, we detected novel FBoVs for the first time in Korea in captive wild felids (four European lynx and a lion) kept at Seoul Zoo. In FBoV-positive fecal samples, not only singular infections but also dual or triple infections with three different species of FBoVs were confirmed, suggesting that three species of FBoVs are already introduced and co-circulated in susceptible host animals in Korea. These results will help expand our understanding of the geographical distribution and host susceptibility of novel FBoVs. Further studies are necessary to determine the infection status of FBoVs in domestic cats and the genetic characteristics of the viruses circulating in Korea.

Comparative Analysis of Sequence Control in Six Series-Connected ITER VS Converters (6 직렬 연결된 ITER VS 컨버터의 시퀀스제어 비교 해석)

  • Jo, Hyunsik;Jeong, Jinyong;Jo, Jongmin;Cha, Hanju
    • The Transactions of the Korean Institute of Power Electronics
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    • v.19 no.5
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    • pp.399-406
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    • 2014
  • This study investigates the structure and operation of the ITER VS converter and proposes a sequence control method for six series-connected VS converters to reduce reactive power. The operation and the proposed sequence control method are verified through RTDS simulation. The ITER VS converter must supply voltage/current to the superconducting magnets for plasma current vertical stabilization, and the four-quadrant operation must proceed without a zero-current discontinuous section. The operation mode of the VS converter is separated into a 12- and 6-pulse circulating current and transition modes according to the size of the load current. The output voltage of the unit VS converter is limited because of the rated voltage; however, the superconducting coil must increase the operating output voltage. Thus, the VS converter must be connected in a 6-series to provide the required operating output voltage. The output voltage of the VS converters is controlled continuously; however, reactive power is limited within a minimized value of the grid. In this study, the unit converter is compared with converters connected in a 6-series to determine a suitable sequence control method. The output voltage is the same in all cases, but the maximum reactive power is reduced from 100% to 73%. This sequence control method is verified through RTDS simulation.

Changes of the growth plate in children: 3-dimensional magnetic resonance imaging analysis

  • Yun, Hyung Ho;Kim, Hyun-Jung;Jeong, Min-Sun;Choi, Yun-Sun;Seo, Ji-Young
    • Clinical and Experimental Pediatrics
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    • v.61 no.7
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    • pp.226-230
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    • 2018
  • Purpose: This pilot study assessed changes in the growth plate and growth rates in children during a 6-month period. Methods: The study included 31 healthy children (17 boys, 14 girls) under evaluation for growth retardation. Height, weight, bone age, insulin like growth factor-1 (IGF-1), and insulin like growth factor binding protein 3 (IGF-BP3) were measured at baseline and after 6 months. In addition, the diameter, thickness, and volume of the femoral and tibial growth plates were measured using magnetic resonance imaging. Results: The mean bone age in boys and girls was 11.7 and 10.7 years, respectively. In boys, height (z score) (-0.2 vs. 0.0), weight (z score) (0.8 vs. 1.1), body mass index (BMI) (z score) (1.27 vs. 1.5), IGF-1 (ng/mL) (343.6 vs. 501.8), and IGF-BP3 (ng/mL) (5,088.5 vs. 5,620.0) were significantly higher after 6 months. In girls, height (z score) (-1.0 vs. -0.7), weight (z score) (-0.5 vs. 0.1), BMI (z score) (-0.02 vs. 0.3), IGF-1 (ng/mL) (329.3 vs. 524.6), and IGF-BP3 (ng/mL) (4,644.4 vs. 5,593.6) were also significantly higher after 6 months. In both sexes, the mean diameter and volume of the femoral and tibial growth plates were significantly increased 6 months later. Conclusion: No significant correlation was found between changes in the growth plate and clinical parameters in children with growth retardation in this study, other than correlations of change in femoral diameter with weight and BMI. A larger, long-term study is needed to precisely evaluate the correlation between change in the growth plate and growth.

Chemical Composition and Fatty Acid Profile in Crossbred (Bos taurus vs. Bos indicus) Young Bulls Finished in a Feedlot

  • Ducatti, Taciana;do Prado, Ivanor Nunes;Rotta, Polyana Pizzi;do Prado, Rodolpho Martin;Perotto, Daniel;Maggioni, Daniele;Visentainer, Jesui Vergilio
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.3
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    • pp.433-439
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    • 2009
  • This study was conducted to determine the effect of breed on the chemical composition of first (PUR1) and second (PUR2) generations of $Purun{\tilde{a}}$ young bulls, and to compare both generations with different genetic groups: CAN vs. ANG; CAR; and CHA vs. CAR. Thirty bulls were used. The animals from the PUR2 and CHA vs. CAR genetic groups featured higher (p<0.05) moisture percentage in comparison to the PUR1, CAR and CAN vs. ANG groups. The moisture percentage was similar (p>0.05) between PUR2 and CHA vs. CAR animals. The same was observed among the PUR1, CAR, CAN vs. ANG and CHA vs. CAR animals. There was no difference (p>0.05) among genetic groups for ash, total lipids and total cholesterol. The PUR1, CAR and CAN vs. ANG specimens had higher (p<0.05) crude protein percentages as compared to PUR2 and CAN vs. CAR animals. The fatty acid profile was different (p<0.05) among genetic groups. However, the percentages of SFA, MUFA, PUFA, n-6, n-3, PUFA:SFA, and n-6:n-3 were similar (p>0.05) among genetic groups.