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A Study of Energy Dependency in Intensity Modulated Radiation Therapy of Lung Cancer (폐암환자의 세기조절방사선치료에서 에너지에 따른 선량분포 특성 비교)

  • Kim, Sung-Kyu;Kim, Myung-Se;Yun, Sang-Mo
    • Progress in Medical Physics
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    • v.19 no.3
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    • pp.191-199
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    • 2008
  • PTV considered for the energy, dose distribution exposed to lung and spinal cord, and the characteristic of DVH(Dose Volume Histogram) were compared and investigated by planning the intensity modulated radiation therapy (IMRT) using the photon energies of 6 MV and 10 MV according to tumor location like as the anterior, middle, and posterior regions of lung, and the mediastinum region in lung cancer patients. Our institution installed the linear accelerator (Varian 21 EX-s, USA) equipped with 120 multileaf collimator for lung cancer patients, which is producing the photon energies of 6 MV and 10 MV, and radiation therapy planning was performed with ECLIPSE system (Varian, SomaVision 6.5, USA), which support inverse treatment planning. The tomographic images of 3 mm slice thickness for lung cancer patients were acquired using planning CT, and acquired tomographic images were sent to the Varis system, and then treatment planning was performed in the ECLIPSE system. The radiation treatment planning of the IMRT was processed from various angles according to the regions of the tumor, and using various beam lines according to the size and location of the tumor. The investigation of the characteristic of dose distributions for the energy of 6 MV and 10 MV according to tumor locations in lung cancer patients resulted that the maximum dose of 10 MV energy was 1.2% less than that of 6 MV energy without depending on the tumor location of lung cancer, and the reduction effects of MU were occurred from 10 to 25 MU. Radiation dose exposed to the lung satisfied the less 30% of V20, however radiation dose in 6 MV energy was from 0.1% to 0.5% less than that in 10 MV energy. Radiation dose exposed to the spinal cord for 6 MV energy was from 0.6% to 2.1% less than that for 6 MV energy.

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Comparison and Evaluation of radiotherapy plans by multi leaf collimator types of Linear accelerator (선형가속기의 다엽콜리메이터 형태에 따른 치료계획 비교 평가)

  • Lim, Ji Hye;Chang, Nam Joon;Seok, Jin Yong;Jung, Yun Ju;Won, Hui Su;Jung, Hae Youn;Choi, Byeong Don
    • The Journal of Korean Society for Radiation Therapy
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    • v.30 no.1_2
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    • pp.129-138
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    • 2018
  • Purpose : An aim of this study was to compare the effect of multi leaf collimator(MLC) types for high dimension radiotherapy in treatment sites used clinically. Material and Method : 70 patients with lung cancer, spine cancer, prostate cancer, whole pelvis, head and neck, breast cancer were included in this study. High definition(HD) MLC of TrueBeam STx (Varian Medical system, Palo Alto, CA) and millenium(M) MLC of VitalBeam (Varian Medical system, Palo Alto, CA) were used. Radiotherapy plans were performed for each patient under same treatment goals with Eclipse (Version 13.7, Varian Palo Alto USA, CA). To compare the indicators of the radiotherapy plans, planning target volume(PTV) coverage, conformity index(CI), homogeneity index(HI), and clinical indicators for each treatment sites in normal tissues were evaluated. To evaluate low dose distribution, $V_{30%}$ values were compared according to MLC types. Additionally, length and volume of targets for each treatment sites were investigated. Result : In stereotatictic body radiotherapy(SBRT) plan for lung, the average value of PTV coverage was reduced by 0.52 % with HD MLC. With SBRT plan using HD MLC for spine, the average value of PTV coverage decreased by 0.63 % and maximum dose decreased by 1.13 %. In the test of CI and HI, the values in SBRT plan with HD MLC for spine were 1.144, 1.079 and the values using M MLC were 1.160, 1.092 in SBRT plan for lung, The dose evaluation of critical organ was reduced by 1.48 % in the ipsilateral lung mean dose with HD MLC. In prostate cancer volumetric modulated arc therapy(VMAT) with HD MLC, the mean dose and the $V_{30}$ of bladder and the mean dose and the $V_{25}$ of rectum were reduced by 0.53 %, 1.42 %, 0.97 %, and 0.69 %, respectively (p<0.05). The average value of heart mean dose was reduced by 0.83 % in breast cancer VMAT with M MLC. Other assessment indices for treatment sites showed no significant difference between treatment plans with two types of MLC. Conclusion : Using HD MLC had a positive impact on the PTV coverage and normal tissue sparing in usually short or small targets such as lung and spine SBRT and prostate VMAT. But, there was no significant difference in targets with long and large such as lung, head and neck, and whole pelvis for VMAT.

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The Variation of Surface Dose by Beam Spoiler in 10 MV Photon Beam from Linear Accelerator (선형가속기 10 MV 광자선에서 산란판(Beam Spoiler) 사용 시 표면선량 변화)

  • Bae, Seong-Cheol;Kim, Jun-Ho;Lee, Choul-Soo
    • The Journal of Korean Society for Radiation Therapy
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    • v.18 no.1
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    • pp.21-28
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    • 2006
  • Purpose: The purpose of this study is to find a optimal beam spoiler condition on the dose distribution near the surface, when treating a squamous cell carcinoma of the head and neck and a lymphatic region with 10 MV photon beam. The use of a optimal spoiler allows elivering high dose to a superficial tumor volume, while maintaining the skin-sparing effect in the area between the surface to the depth of 0.4 cm. Materials and Methods: The lucite beam spoiler, which were a tissue equivalent, were made and placed between the surface and the photon collimators of linear accelerator. The surface-dose, the dose at the depth of 0.4 cm, and the maximum dose at the dmax were measured with a parallel-plate ionization chamber for $5{\times}5cm\;to\;30{\times}30cm^2$ field sizes using lucite spoilers with different thicknesses at varying skin-to-spoiler separation (SSS). In the same condition, the dose was measured with bolus and compared with beam spoiler. Results: The spoiler increased the surface and build-up dose and shifted the depth of maximum dose toward the surface. With a 10 MV x-ray beam and a optimal beam spoiler when treating a patient, a similer build-up dose with a 6 MV photon beam could be achieved, while maintaining a certain amount of skin spring. But it was provided higher surface dose under SSS of less than 5 cm, the spoiler thickness of more than 1.8 cm or more, and larger field size than $20{\times}20cm^2$ provided higher surface dose like bolus and obliterated the spin-sparing effect. the effects of the beam spoiler on beam profile was reduced with increasing depths. Conclusion: The lucite spoiler allowed using of a 10 MV photon beam for the radiation treatment of head and neck caner by yielding secondary scattered electron on the surface. The dose at superficial depth was increased and the depth of maximum dose was moved to near the skin surface. Spoiling the 10 MV x-ray beam resulted in treatment plans that maintained dose homogeneity without the consequence of increased skin reaction or treat volume underdose for regions near the skin surface. In this, the optimal spoiler thickeness of 1.2 cm and 1.8 cm were found at SSS of 7 cm for $10{\times}10cm^2$ field. The surface doses were measured 60% and 64% respectively. In addition, It showed so optimal that 94% and 94% at the depth of 0.4 cm and dmax respectively.

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Vegetative Growth, Productivity, and Fruit Quality in Tall Spindle of 'Fuji'/M.9 Apple Trees (키큰방추형 '후지'/M.9 사과나무의 영양생장, 생산성 및 과실품질)

  • Yang, Sang-Jin;Sagong, Dong-Hoon;Yoon, Tae-Myung;Song, Yang-Yik;Park, Moo-Yong;Kweon, Hun-Joong
    • Horticultural Science & Technology
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    • v.33 no.2
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    • pp.155-165
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    • 2015
  • Well-feathered (over 10 feathers) 'Fuji'/M.9 apple trees were planted at $3.0{\times}1.0m$ and trained to slender spindle with 2.5 m height or to tall spindle with 3.5 m height, and the vegetative growth, productivity, and fruit quality of two training systems were compared for 8 years. The canopy volume of the tall spindle trees surpassed that of the slender spindle trees 4 years after planting and was 25% larger than that of the slender spindle trees 5 years after planting. The accumulated yield over 8 years for the tall spindle system was 14% higher than that of the slender spindle system. Alternate bearing and incidence of marssonina blotch were observed in both treatments after 5 years of planting. There was often vegetative imbalance in the trees however, the degree of yield loss and vegetative imbalance of the tall spindle trees was lower than those of the slender spindle trees. Soluble solid content and fruit red color of the tall spindle trees were higher than that of the slender spindle trees in 5 year after planting, resulting from increased light penetration in the canopy due to even distribution of lateral branches and from fruit bearing in different height locations of the trees. In conclusion, increasing the tree height to about 3.5 m using slender spindle 'Fuji'/M.9 apple trees planted with over 333 trees per 10a led to better light penetration, yield and fruit quality compared to a conventional wide training system with the slender spindle.

A Study on the Structure of Biomass Production in Thrifty-Mature Quercus mongolica Stand (신갈나무 장령임분(壯齡林分)의 물질생산(物質生産) 구조(構造)에 관(關)한 연구(硏究))

  • Han, Sang Sup;Kim, Do Young;Sim, Joo Suk
    • Journal of Korean Society of Forest Science
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    • v.81 no.1
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    • pp.1-10
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    • 1992
  • This study was conducted to explain the characters of the structure of biomass production in the thrifty-mature Quercus mongolica stands and investigate the relationships between the leaf weight or leaf area and the sapwood area in the bole. Also we intended to identify the allocation ratio of stem, branches, and leaves or heartwood, sapwood and bark in trees and the characters of productive structure of stem and leaf biomass by the tree height. The results obtained were as follows : 1. The allocation ratio of biomass based on dry weight was 70-84% in stem, 11-25% in branches, and 3-6% in leaves. 2. In the bole, the ratios of composition of heartwood, sapwood, and bark were showed 37-43%, 38-46%, and 16-19%, respectively. 3. The volume of sapmood was exceeded more than that of heartwood in dominant and intermediate trees, while it was reversely appeared in suppressed trees. 4. The weight and area of leases significantly correlated with the sectional area of sapwood in bole (r>0.9. 1% significant level). 5. The ratio of leaf area($m^2$) to sapwood areal($cm^2$), k varied 0.35 to 2.05. 6. The basal diameter and the cross sectional area of a branch significantly correlated with the leaf weight r>0.9. 1% significant level. 7. The leaf weight in a tree is showed a normal distribution curve and the accumulative volume of bole is showed a tapering type.

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Evaluation of Image Quality for Various Electronic Portal Imaging Devices in Radiation Therapy (방사선치료의 다양한 EPID 영상 질평가)

  • Son, Soon-Yong;Choi, Kwan-Woo;Kim, Jung-Min;Jeong, Hoi-Woun;Kwon, Kyung-Tae;Cho, Jeong-Hee;Lee, Jea-Hee;Jung, Jae-Yong;Kim, Ki-Won;Lee, Young-Ah;Son, Jin-Hyun;Min, Jung-Whan
    • Journal of radiological science and technology
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    • v.38 no.4
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    • pp.451-461
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    • 2015
  • In megavoltage (MV) radiotherapy, delivering the dose to the target volume is important while protecting the surrounding normal tissue. The purpose of this study was to evaluate the modulation transfer function (MTF), the noise power spectrum (NPS), and the detective quantum efficiency (DQE) using an edge block in megavoltage X-ray imaging (MVI). We used an edge block, which consists of tungsten with dimensions of 19 (thickness) ${\times}$ 10 (length) ${\times}$ 1 (width) $cm^3$ and measured the pre-sampling MTF at 6 MV energy. Various radiation therapy (RT) devices such as TrueBeam$^{TM}$ (Varian), BEAMVIEW$^{PLUS}$ (Siemens), iViewGT (Elekta) and Clinac$^{(R)}$iX (Varian) were used. As for MTF results, TrueBeam$^{TM}$(Varian) flattening filter free(FFF) showed the highest values of $0.46mm^{-1}$ and $1.40mm^{-1}$ for MTF 0.5 and 0.1. In NPS, iViewGT (Elekta) showed the lowest noise distribution. In DQE, iViewGT (Elekta) showed the best efficiency at a peak DQE and $1mm^{-1}DQE$ of 0.0026 and 0.00014, respectively. This study could be used not only for traditional QA imaging but also for quantitative MTF, NPS, and DQE measurement for development of an electronic portal imaging device (EPID).

Production and CO2 Adsorption Characteristics of Activated Carbon from Bamboo by CO2 Activation Method (CO2 활성화법에 의한 대나무 활성탄 제조와 CO2 흡착 특성)

  • Bak, Young-Cheol;Cho, Kwang-Ju;Choi, Joo-Hong
    • Korean Chemical Engineering Research
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    • v.43 no.1
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    • pp.146-152
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    • 2005
  • The activated carbon was produced from Sancheong bamboo by carbon dioxide gas activation methods. The carbonization of raw material was conducted at $900^{\circ}C$, and $CO_2$ activation reactions were conducted under various conditions: activation temperatures of $750-900^{\circ}C$, flow rates of carbon dioxide $5-30cm^3/g-char{\cdot}min$, and activation time of 2-5 h. The yield, adsorption capacity of iodine and methylene blue, specific surface area and pore size distribution of the prepared activated carbons were measured. The adsorption capacity of iodine (680.8-1450.1 mg/g) and methylene blue (23.5-220 mg/g) increased with increasing activation temperature and activation time. The adsorption capacity of iodine and methylene blue increased with the $CO_2$ gas quantity in the range of $5-18.9cm^3/g-char{\cdot}min$. But those decreased over those range due to the pore shrinkage. The specific volume of the mesopore and macropore of bamboo activated carbon were $0.65-0.91cm^3/g$. Because of this large specific volume, it can be used to the biological activated carbon process. Bamboo activated carbon phisically adsorbed the $CO_2$ of maximum 106 mg/g-A.C in the condition of 90% $CO_2$ and adsorption temperature of $20^{\circ}C$. The $CO_2$ adsorption ability of bamboo activated carbon was not changed in the 5 cyclic test of desorption and adsorption.

Evaluation after Applicated a Mold to a Paraneoplastic Autoimmune Multiorgan Syndrome Patient with Hypervascular Ulcer in the Oral Cavity during Treatment with Mold Brachytherapy (Paraneoplastic Autoimmune Multiorgan Syndrome으로 인하여 구강 내 국소적으로 발생한 과다혈관성 궤양의 방사선 근접치료 시 자체 제작한 Mold의 유용성 평가)

  • Park, Ju-Kyeong;Lee, Sun-Young;Lim, Seok-Geon;Kwak, Geun-Tak;Lee, Seung-Hun;Kim, Yang-Su;Hwang, Ho-In;Cha, Seok-Yong
    • The Journal of Korean Society for Radiation Therapy
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    • v.21 no.1
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    • pp.25-31
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    • 2009
  • Purpose: Evaluate the mold we have made to improve the reproducibility of the patient position and make homogeneous dose distribution to the treatment volume effectively when treating the patient who has hypervascular ulcer on her tongue caused by paraneoplastic autoimmune multiorgan syndrome by mold brachytherapy. Materials and Methods: The mold is consisted of upper and lower parts. We inserted 2 mm of lead sheet on the gums toward the oral cavity to protect them from unnecessary irradiation during the treatment. We had planned on orthogonal images obtained the patient. 200 cGy was delivered in every fraction with a total dose of 3000 cGy. To evaluate the effect of the lead sheet, we made a measurement with a phantom that has gums and tongue made of tissue with an equivalent material (bolus). Five of TLDs were placed on the interesting points of gums to measure the dose during irradiation with lead sheet and without lead sheet for three times respectively. Results: The result of the measurement without lead sheet are A: 33.9 cGy, B: 30.1 cGy, C: 31.8 cGy, D: 23.3 cGy, E: 24.1 cGy. The results of measurement with lead sheet are A: 20.6 cGy, B: 18.8 cGy, C: 19.6 cGy, D: 14.7 cGy, E: 15.1 cGy. Conclusion: Since we are using the mold made in our department during the treatment of the patient with hypervascular ulcer on tongue, we could deliver a proper dose to the treatment volume. In addition, the mold provided highly accurate and reproducible treatment and reduced the dose to the gums and teeth. Therefore, the possibility of side effects could be decreased significantly.

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Evaluation of the Usefulness for VMAT of multiple brain metastasis using jaw tracking (Jaw tracking을 이용한 다발성 뇌 전이의 용적세기조절회전치료에 대한 유용성 평가)

  • Kim, Tae Won;Yoo, Soon Mi;Jeon, Soo Dong;Yoon, In Ha;Back, Geum Mun
    • The Journal of Korean Society for Radiation Therapy
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    • v.30 no.1_2
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    • pp.73-81
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    • 2018
  • Purpose : The aims of this study were to compare and assess the effectiveness of Volumetric Modulated Arc Therapy(VMAT) using jaw tracking(JT) and fixed jaw(FJ) in radiation therapy of multiple brain metastasis. Methode and material : Among the patients with Multiple Brain Metastasis treated with jaw tracking, 10 patients with more than 6 tumors and with the size of radiation field $14{\times}14cm^2$ or more were included. Each Treatment plans with jaw tracking(JT) and fixed jaw(FJ) was established with Eclipse (Ver. 13.6 Varian, USA). Gamma Index (3 mm, 3 % confidence interval - 95 %) and maximum dose difference were measured with an electronic portal imaging device(EPID). The $D_{max}$ and $D_{mean}$ of Organ At Risk(OAR) were assessed and compared, and the Conformity Index(CI) and Homogeneity Index(HI) were evaluated. Result : Evaluating jaw tracking(JT) and fixed jaw(FJ) outcomes, in all cases, Gamma Index met the permissible standard of 3 mm, 3 % confidence intervals of 95 %. The maximum dose difference value from the areas with leaf end transmission was measured at a maximum of 98.4 % and an average of 43.6 % in clockwise(CW), and 67.9 % and 41.0 % for each in Counter-Clockwise(CCW). With jaw tracking, the maximum value of $D_{max}$ for each normal organ in OAR decreased in 15.36 %~74.59 % with the average value decreasing in 2.84 %~39.80 %. The maximum value of $D_{mean}$ in OAR decreased in 27.90 %~65.23 %, with the average value decreasing in 7.70 %~41.71 %. No change has been found in Conformity Index and Homogeneity Index values. Conclusion : When Jaw tracking is used in treating patients with multiple brain metastasis with VMAT, the unnecessary exposure due to leakage and transmission of radiation in unspecified areas was reduced, without affecting the dose distribution of the planning target volume(PTV), and the availability of radiation therapy with lower doses in normal organs is expected.

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Estimating Optimal Timber Production for the Economic and Public Functions of the National Forests in South Korea (국유림의 경제적·공익적 기능을 고려한 적정 목재생산량 추정)

  • Yujin Jeong;Younghwan Kim;Yoonseong Chang;Dooahn Kwak;Gihyun Park;Dayoung Kim;Hyungsik Jeong;Hee Han
    • Journal of Korean Society of Forest Science
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    • v.112 no.4
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    • pp.561-573
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    • 2023
  • National forests have an advantage over private forests in terms of higher investment in capital, technology, and labor, allowing for more intensive management. As such, national forests are expected to serve not only as a strategic reserve of forest resources to address the long-term demand for timber but also to stably perform various essential forest functions demanded by society. However, most forest stands in the current national forests belong to the fourth age class or above, indicating an imminent timber harvesting period amid an imbalanced age class structure. Therefore, if timber harvesting is not conducted based on systematic management planning, it will become difficult to ensure the continuity of the national forests' diverse functions. This study was conducted to determine the optimal volume of timber production in the national forests to improve the age-class structure while sustainably maintaining their economic and public functions. To achieve this, the study first identified areas within the national forests suitable for timber production. Subsequently, a forest management planning model was developed using multi-objective linear programming, taking into account both the national forests' economic role and their public benefits. The findings suggest that approximately 488,000 hectares within the national forests are suitable for timber production. By focusing on management of these areas, it is possible to not only improve the age-class distribution but also to sustainably uphold the forests' public benefits. Furthermore, the potential volume of timber production from the national forests for the next 100 years would be around 2 million m3 per year, constituting about 44% of the annual domestic timber supply.