• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2021.10a
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• pp.128-130
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• 2021

This study aims to implement a Regression Analysis system for predicting the appropriate production of flatfish. Due to Korea's signing of FTAs with countries around the world and accelerating market opening, Korean flatfish farming businesses are experiencing many difficulties due to the specificity and uncertainty of the environment. In addition, there is a need for a solution to problems such as sluggish consumption and price drop due to the recent surge in imported seafood such as salmon and yellowtail and changes in people's dietary habits. in this study, Using the python module, xlwings, it was used to obtain for the production amount of flatfish and to predict the amount of flatfish to be produced later. was used to predict the amount of flatfish to be produced in the future. Therefore, based on the analysis results of this prediction of flatfish production, the flatfish aquaculture industry will be able to come up with a plan to achieve an appropriate production volume and control supply and demand, which will reduce unnecessary economic loss and promote new value creation based on data. In addition, through the data approach attempted in this study, various analysis techniques such as artificial neural networks and multiple regression analysis can be used in future research in various fields, which will become the foundation of basic data that can effectively analyze and utilize big data in various industries.

• Journal of Environmental Health Sciences
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• v.49 no.3
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• pp.169-177
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• 2023

Background: The Korea Centers for Disease Control and Prevention (KCDC) has identified cases of people suspected of suffering lung disease potentially caused by chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT) used in humidifier disinfectants (HDs). The Korean Ministry of Environment (MoE) epidemiological investigation and toxicity test study found that HDs caused health damage such as asthma and lung disease. Objectives: The main purposes of this study were to classify the HD exposure rating and to analyze the exposure characteristics that affect exposure to CMIT/MIT HDs. Methods: The exposure characteristics and socio-demographic characteristics of victim participants using CMIT/MIT HDs were investigated through questionnaires. An inhalation no observed adverse effect level (NOAEL) for CMIT/MIT was produced based on inhalation toxicity values. Exposure ratings (class 1~class 2) were cross-tabulated with clinical ratings (acceptable~unacceptable). A correlation analysis was conducted with the main exposure characteristics that affect the exposure concentration of CMIT/MIT HDs. Results: The concentration in indoor air of CMIT/MIT was 8.75±25.40 ㎍/m³, and the exposure concentration was 2.30±6.29 ㎍/m³. The CMIT/MIT exposure rating of 67 participants with high exposures of not more than MOE 100 were evaluated as 14.5%, while the damage participants who matched the clinical rating made up 4.5%. The exposure concentration of CMIT/MIT showed a positive correlation with the daily usage amount and usage frequency, and a negative correlation with volume of the indoor environment. Conclusions: A new exposure rating could be suggested and calculated based on the MOE, and the factors affecting the exposure concentration could be identified.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.28 no.6B
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• pp.697-707
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• 2008

The grid-based KIneMatic wave STOrm Runoff Model (KIMSTORM) by Kim (1998) predicts the temporal variation and spatial distribution of overland flow, subsurface flow and stream flow in a watershed. The model programmed with C++ language on Unix operating system adopts single flowpath algorithm for water balance simulation of flow at each grid element. In this study, we attempted to improve the model by converting the code into FORTRAN 90 on MS Windows operating system and named as ModKIMSTORM. The improved functions are the addition of GAML (Green-Ampt & Mein-Larson) infiltration model, control of paddy runoff rate by flow depth and Manning's roughness coefficient, addition of baseflow layer, treatment of both spatial and point rainfall data, development of the pre- and post-processor, and development of automatic model evaluation function using five evaluation criteria (Pearson's coefficient of determination, Nash and Sutcliffe model efficiency, the deviation of runoff volume, relative error of the peak runoff rate, and absolute error of the time to peak runoff). The modified model adopts Shell Sort algorithm to enhance the computational performance. Input data formats are accepted as raster and MS Excel, and model outputs viz. soil moisture, discharge, flow depth and velocity are generated as BSQ, ASCII grid, binary grid and raster formats.

• Korean Journal of Exercise Nutrition
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• v.13 no.1
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• pp.1-7
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• 2009

It has been shown that both caloric restriction and exercise, enhances glucose uptake through translocation of GLUT-4 protein. It remains unclear how exercise and caloric restriction affect the changes in VAMP (vesicle-associated membrane protein) in skeletal muscle and GLUT-2 in liver. This study investigated the effects of exercise training and caloric restriction on the expressions of glucose transport relating proteins in muscle and liver tissues in diabetic rats. Forty male Sprague-Dawley rats (250±10 g; 8 week in age) were assigned equally to four different groups; control (C), exercise only (E), dietary restriction only (D) and dietary restriction and exercise (DE). Daily food consumption was monitored to establish baseline intake. Both C and E groups consumed baseline food intake while D and DE groups were provided with only 60% of baseline total food intake. Forty-eight hours after intraperitoneal injection of STZ (50 mg/kg), diabetes was confirmed (8-hr fasting blood glucose levels ≥300 mg/dl). Rats in the E and DE groups exercised on a motorized treadmill for 30 min/d, 5 days/week for 4 weeks (5 min running at 3 m/min, 0% grade; 8 m/min for the next 5min, and then 15 m/min for 20 min). Rats were sacrificed 48 hrs after the last bout of exercise. Soleus muscle and liver were extracted to analyze for GLUT-4, VAMP-2, and GLUT-2, respectively. All variables were analyzed using the Western Blotting technique. All values were expressed as optical volume measured by optical density. A Two-way ANOVA was used to examine the difference between groups and applied Duncan's test for post-hoc. No significant differences in GLUT-2 expression were found among groups. However, E (280133±13228 arbitrary units{AU}) and DE (268833±14424 AU) groups showed significantly higher (p<.001) levels of GLUT-4 as compared with C (34461±2099 AU) and D groups (27847±703 AU). VAMP-2 protein expression increased (p<.001) in E (184137±7803 AU) and DE (189800±10856 AU) groups as compared to C (74201±8296AU) and D (72967±863 AU) groups. These results suggest that either exercise with or without caloric restriction increases the up-regulation of GLUT-4 and VAMP-2 in skeletal muscle of diabetic rats. However, GLUT-2 protein in liver was not affected by either exercise or exercise with caloric restriction.

• Korean Journal of Culture and Social Issue
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• v.20 no.2
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• pp.155-176
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• 2014

The previous researches of gambling have been rather focused on the legal gambling industry and gambling addiction and ignored the issue of illegal gambling. But, illegal gambling in Korea has been continuously growing in its volume and the numbers of the relevant mental and social problems such as gambling addiction, crimes, suicides, and etc. have been increasing rapidly. The present study investigated the psychological characteristics of illegal gamblers with comparing gamblers who never experienced illegal gambling (NE), who experienced illegal gambling but participate mainly in legal gambling (EIG), and who participate mainly in illegal gambling (MIG). 1317 NEs, 177 EIGs, and 37 MIGs were recruited and completed an online survey that measured individual dispositions (risk-taking tendency, regulatory focus, locus of control), attitudes towards gambling regulations, misconception of illegal gambling, motives (monetary, excitement, socialization), and emotions. First, EIGs and MIGs, compared to NEs, preferred risk-taking, and EIGs were more promotion focused than NEs. Also, EIGs perceived illegal gambling as less illegal and tended to hold more misconceptions about illegal gambling, compared to NEs. Furthermore, EIGs and MIGs had stronger monetary and excitement motivation than NEs. Finally, MIGs were more likely to feel anxious than other groups. Focusing on the illegality of gambling, the characteristics of illegal gamblers are discussed and political implication on illegal gambling is suggested.

• The Journal of the Convergence on Culture Technology
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• v.9 no.6
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• pp.867-873
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• 2023

In this study, for the purpose of standardized quality control of a cold medicine, we simultaneous analyzed four main chemical components of a cold medicine: acetaminophen, caffeine, methyl paraben, and propyl paraben. The sample was subjected to quantitative analysis using high performance liquid chromatography (HPLC), after pretreatment of four components. The experiment was carried out by using Isocratic elution at wavelength of 270nm. Acetonitrile and water (H₂O) were used as a mobile phase at a flow rate of 1.0mL/min in a commercial C18 reversed-phase column. A volume of 10uL cold medicine were injected into the column with column oven temperature at 35℃. As a result of the experiment, the values of Resolution were 4.983, 1.596, 5.519, and 1.678 respectively-well over Rs >1.5, which indicates that the separation of four components were efficient. In addition, value of symmetry factor of the components was 1.056, 1.069, 1.032, and 1.133 respectively, to show its symmetrical stability. The calibration curve of all four components exhibits good linearity with R² >0.9995 to 0.9999. Furthermore, the limit of detection(LOD) were between 0.0118 to 1.5973 mg/mL, while the limit of quantification (LOQ) were between 0.0353 to 4.7919 ㎍/mL with the recovery rate of 79.6% ~ 120.5%. The results of this study showed an efficient quality evaluation of a simultaneous analysis method for cold medicine components.

• Nuclear Engineering and Technology
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• v.55 no.10
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• pp.3543-3548
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• 2023

Shutdown chemistry evolution is performed in nuclear power plants at each refueling outage (RFO) to establish safe conditions to open system and minimize inventory of corrosion products in the reactor coolant system (RCS). After hydrogen peroxide is added to RCS during shutdown chemistry evolution, corrosion products are released and are removed by filters and ion exchange resins in the chemical volume control system (CVCS). Shutdown chemistry evolution including RCS clean-up time to remove released corrosion products impacts the critical path schedule during RFOs. The estimation of clean-up time prior to RFO can provide more reliable actions for RCS clean-up operations and transients to operators during shutdown chemistry. Electric Power Research Institute (EPRI) shutdown calculator (SDC) enables to provide clean-up time by Co-58 peak activity through operational data from nuclear power plants (NPPs). In this study, we have investigated the results of EPRI SDC by shutdown chemistry data of Co-58 activity using NPP data from previous cycles and modeled the estimated clean-up time by EPRI SDC using average Co-58 activity of the NPP. We selected two RFO data from the NPP to evaluate EPRI SDC results using the purification time to reach to 1.3 mCi/cc of Co-58 after hydrogen peroxide addition. Comparing two RFO data, the similar purification time between actual and computed data by EPRI SDC, 0.92 and 1.74 h respectively, was observed with the deviation of 3.7-7.2%. As the modeling the estimated clean-up time, we calculated average Co-58 peak concentration for normal cycles after cycle 10 and applied two-sigma (2σ, 95.4%) for predicted Co-58 peak concentration as upper and lower values compared to the average data. For the verification of modeling, shutdown chemistry data for RFO 17 was used. Predicted RCS clean-up time with lower and upper values was between 21.05 and 27.58 h, and clean-up time for RFO 17 was 24.75 h, within the predicted time band. Therefore, our calculated modeling band was validated. This approach can be identified that the advantage of the modeling for clean-up time with SDC is that the primary prediction of shutdown chemistry plans can be performed more reliably during shutdown chemistry. This research can contribute to improving the efficiency and safety of shutdown chemistry evolution in nuclear power plants.

• Korean Journal of Radiology
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• v.22 no.6
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• pp.880-889
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• 2021

Objective: This study aimed to investigate the regional amyloid burden and myocardial deformation using T1 mapping and strain values in patients with cardiac amyloidosis (CA) according to late gadolinium enhancement (LGE) patterns. Materials and Methods: Forty patients with CA were divided into 2 groups per LGE pattern, and 15 healthy subjects were enrolled. Global and regional native T1 and T2 mapping, extracellular volume (ECV), and cardiac magnetic resonance (CMR)-feature tracking strain values were compared in an intergroup and interregional manner. Results: Of the patients with CA, 32 had diffuse global LGE (group 2), and 8 had focal patchy or no LGE (group 1). Global native T1, T2, and ECV were significantly higher in groups 1 and 2 than in the control group (native T1: 1384.4 ms vs. 1466.8 ms vs. 1230.5 ms; T2: 53.8 ms vs. 54.2 ms vs. 48.9 ms; and ECV: 36.9% vs. 51.4% vs. 26.0%, respectively; all, p < 0.001). Basal ECV (53.7%) was significantly higher than the mid and apical ECVs (50.1% and 50.0%, respectively; p < 0.001) in group 2. Basal and mid peak radial strains (PRSs) and peak circumferential strains (PCSs) were significantly lower than the apical PRS and PCS, respectively (PRS, 15.6% vs. 16.7% vs. 26.9%; and PCS, -9.7% vs. -10.9% vs. -15.0%; all, p < 0.001). Basal ECV and basal strain (2-dimensional PRS) in group 2 showed a significant negative correlation (r = -0.623, p < 0.001). Group 1 showed no regional ECV differences (basal, 37.0%; mid, 35.9%; and apical, 38.3%; p = 0.184). Conclusion: Quantitative T1 mapping parameters such as native T1 and ECV may help diagnose early CA. ECV, in particular, can reflect regional differences in the amyloid deposition in patients with advanced CA, and increased basal ECV is related to decreased basal strain. Therefore, quantitative CMR parameters may help diagnose CA and determine its severity in patients with or without LGE.

• KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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• v.29 no.3
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• pp.145-151
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• 2023

In order to extend shelf life for rockfish fillets by modified atmosphere packaging (MAP), different package atmospheres were compared in the product quality preservation. Firstly, CO₂ solubility was measured at 0, 5, 10, and 15℃ to be incorporated into the mathematical model to predict the volume and CO₂ concentration of the package at expected storage temperature. The CO₂ solubility given in Henry's constant decreased with temperature to be fitted with a linear equation. Then air packaging as control and four MAP conditions of 100 g fillets were prepared and stored for duration of 5 days at 10℃ to compare them in the quality preservation effect. Four MAP conditions employed were CO₂(60):O₂(30):N₂(10), CO₂(60):O₂(0):N₂(40), CO₂(30):O₂(30):N₂(40) andCO₂(30):O₂(0):N₂(70). MAP conditions with high CO₂ concentration inhibited total aerobic bacteria, and the conditions containing O₂ led to low TVB-N. MAP of CO₂(60):O₂(30):N₂(10) was found to be the best condition for rockfish fillet preservation considering total aerobic bacteria growth and nitrogenous volatiles production.

• Journal of Korean Neurosurgical Society
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• v.67 no.3
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• pp.333-344
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• 2024

Objective : Markers of neuroinflammation during ischemic stroke are well characterized, but additional markers of neural damage are lacking. The study identified associations of behavioral disorders after stroke with histologic neural damage and molecular biological change. Methods : Eight-week-old, 25 g male mice of the C57BL/6J strain were subjected to middle cerebral artery occlusion (MCAO) to induce ischemic stroke. The control group was a healthy wild type (WT), and the experimental group were designed as a low severity MCAO1 and a high severity MCAO2 based on post-stroke neurological scoring. All groups underwent behavioral tests, realtime polymerase chain reaction, triphenyltetrazolium chloride (TTC) staining and Hematoxylin and Eosin staining. One-way analysis of variance was used to analyze statistical significance between groups. Results : In TTC staining, MCAO1 showed 29.02% and MCAO2 showed 38.94% infarct volume (p<0.0001). The pro-inflammatory cytokine interleukin (IL)-1β was most highly expressed in MCAO2 (WT 0.44 vs. MCAO1 2.69 vs. MCAO2 5.02, p<0.0001). From the distance to target in the Barnes maze test, WT had a distance of 178 cm, MCAO1 had a distance of 276 cm, and MCAO2 had a distance of 1051 (p=0.0015). The latency to target was 13.3 seconds for WT, 27.9 seconds for MCAO1, and 87.9 seconds for MCAO2 (p=0.0007). Prospero homeobox 1 (Prox1) was most highly expressed in MCAO2 (p=0.0004). Doublecortin (Dcx) was most highly expressed in MCAO2 (p<0.0001). Conclusion : The study demonstrated that histological damage to neural cells and changes in brain mRNA expression were associated with behavioral impairment after ischemic stroke. Prox1 and Dcx may be biomarkers of neural damage associated with long-term cognitive decline, and increased expression at the mRNA level was consistent with neural damage and long-term cognitive dysfunction.