• Biomolecules & Therapeutics
• /
• v.1 no.2
• /
• pp.204-210
• /
• 1993

The distribution and excretion of DWC-751, a new cephalosporin, were examined in rats and mice following a single intravenous administration. DWC-751 in plasma and urine was determined by both HPLC and microbiological assay. The plasma concentration of the drug declined biexponentially. The initial and terminal half lives of the drug were 3.0 and 28.3 min, respectively. Binding of the drug to plasma proteins was 42.3%. The distribution volume at steacly-state ($Vd_{ss}$) was only 0.341 ι/kg, which is well correlated with the low n-octanol/water partition coefficient of the drug ($K_{o/w{\cong}0$) Actually, the drug was distributed to liver, kidney and lung with very low organ/plasma concentration ratio. The drug, was excreted mainly via renal excretion, i.e., the total($CL_T$) and apparent renal($CL_{R}$) clearances of the drug were 10.8 and 7.5 ml/min/kg, respectively.

• Journal of the Korean Ceramic Society
• /
• v.29 no.12
• /
• pp.956-962
• /
• 1992

The predominant sintering mechanisms of low firing temperature ceramic substrate which consists of borosilicate glass containing alumina as a filler are the rearrangement of alumina particles and the viscous flow of glass powders. In this system, sintering condition depends on the volume ratio of alumina to glass and on the particle size. When the substrate contains about 35 vol% alumina filler and the average alumina particle size is 4 $\mu\textrm{m}$, the best firing condition is obtained at the temperature range of 900∼1000$^{\circ}C$. The extensive rearrangement behavior occurs at these conditions, and the optimum sintering condition is attained by smaller size of glass particles, too. The formation of cristobalite during sintering causes the difference of thermal expansion coefficient between the substrate and Si chip. This phenomenon degradates the capacity of Si chip. Therefore, the crystallization should be prevented. In the alumina filled borosilicate glass system, the crystallization does not occur. This effect may have some relation with aluminum ions in alumina. For aluminum ions diffuse into glass matrix during sintering, functiong as network former.

• Journal of the Korean Society of Safety
• /
• v.29 no.6
• /
• pp.151-157
• /
• 2014

This study deals with the rear-end collision at roundabouts. The purpose of this study is to develop the accident models of rear-end collision in Korea. In pursuing the above, this study gives particular attention to developing the appropriate models using Poisson, negative binomial model, ZAM, multiple linear and nonlinear regression models, and statistical analysis tools. The main results are as follows. First, the Vuong statistics and overdispersion parameters indicate that ZIP is the most appropriate model among count data models. Second, RMSE, MPB, MAD and correlation coefficient tests show that the multiple nonlinear model is the most suitable to the rear-end collision data. Finally, such the independent variables as traffic volume, ratio of heavy vehicle, number of circulatory roadway lane, number of crosswalk and stop line are adopted in the optimal model.

• Journal of Advanced Marine Engineering and Technology
• /
• v.39 no.5
• /
• pp.548-553
• /
• 2015

The conventional ejector-diffuser system makes use of high pressure primary stream to propel the secondary stream through pure shear action for the purposes of transport or compression of fluid. It has been widely used in many industrial applications such as seawater desalination, solar refrigeration, marine engineering, etc. The present study is performed numerically to study the performance of a two-stage ejector-diffuser system. The detailed flow phenomenon of the ejector-diffuser system has been critically predicted by means of the numerical approach using compressible Reynolds averaged Navier-Stokes (RANS) equations. The axi-symmetric supersonic ejector-diffuser flow has been solved by a fully implicit finite volume scheme with a two-equation k-omega turbulence model. The numerical results are validated with existing experimental data. Detailed flow physics and their contributions on ejector performance are detected to compare both single-stage and two-stage ejectors. The performance improvement on the ejector-diffuser system is discussed in terms of the mass flux ratio and the coefficient of power.

• Journal of KSNVE
• /
• v.8 no.5
• /
• pp.849-855
• /
• 1998

An analysis of lateral hydrodynamic forces of compressor labyrinth seals is presented. Basic equations are derived using a two-control-volume model for compressible flow. Blasius' wall friction-factor formula and jet flow theory are used for the calculaton of wall shear stresses and recirculation velocity in the cavity. Linearized zeroth-order and first-order perturbation equations are developed for a small motion about the centered position by expansion in the eccentricity ratio. Integraton of the resultant first-order pressure distribution over the seal defines the rotordynamic coefficients. As an application a rotordynamic analysis of the balance drum labyrinth seal found in an ethylene regrigeration copmressor is carried out. The rotordynamic characteristic results of the labyrinth seal are presented and compared with other types of seals, honeycomb seal and smooth seal.

• Journal of Energy Engineering
• /
• v.24 no.2
• /
• pp.79-83
• /
• 2015

Hydrogen has long been recognized as a fuel having some unique and highly desirable properties, for application as a fuel in engines. Hydrogen has some remarkably high values of the key properties for transport processes, such as kinematic viscosity, thermal conductivity and diffusion coefficient, in comparison to those of the other fuels. Such differences together with its extremely low density and low luminosity help to give hydrogen its unique diffusive and heat transfer characteristics. The thermodynamic and heat transfer characteristics of hydrogen tend to produce high compression temperatures that contribute to improvements in engine efficiency and lean mixture operation.

• Journal of the Semiconductor & Display Technology
• /
• v.5 no.3 s.16
• /
• pp.17-21
• /
• 2006

The oxygen barrier films were formed on poly(ethylene terephthalate) (PET) substrate by a sol-gel process using aminoalkoxysilanes. The coating layers were characterized by FT-IR and SEM. The oxygen permeability coefficients of coating films were measured by variable volume method, and then the influences of solvent ratio in sol and film drying temperature on the oxygen barrier properties were investigated. The aminoalkoxysilane coating films exhibited much higher oxygen barrier properties than PET film. The oxygen permeability coefficient of the film coated with each of APTEOS and APTMOS was measured to be $2.96{\times}10^{-6}$ and $3.05{\times}10^{-5}\;GPU$, respectively, while that of PET film was $1.16{\times}10^{-4}\;GPU$.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
• /
• 2000.07a
• /
• pp.869-872
• /
• 2000

The aim of present work was to fabricate the piezoelectric composite materials of low megahertz applications such as non-destructive testing of materials. Among all the various composites, those with PZT rods embedded in Spurrs epoxy with regular periodicity (1-3 connectivity) was fabricated by dice and fill method. The fabricated size of the PZT cell were 0.18X0.18, 0.28X0.28mm$^2$, respectively. And the volume ratio of the PZT cell were 52, 64%, respectively. The resonant frequency and anti-resonant frequency of the composites were 3.5 MHz and 4.3MHz, respectively. The piezoelectric coupling coefficient were about 38 and 37% and the mechanical quality factor were about 12.7 and 22. These value were very different from these of bulk PZT Plate.

• Bulletin of the Korean Chemical Society
• /
• v.20 no.12
• /
• pp.1409-1412
• /
• 1999

The spectrophotometric determination method of scandium with eriochrome cyanine R (ECR) and the composition ratio of the complex were investigated in the presence of surfactants. A volume of 5 mL of 1.0×$10^{-3}$ M ECR and 10 mL of 2.0×$10^{-4}$ M CTMAB are necessary for the determination of 1.0×$10 ^{-7}$ ~ 3.0×$10^{-6}$ M Sc(III) at pH 6.5. The apparent molar absorption coefficient of the Sc(III)-ECR-CTMAB, ternary complex at 610 nm is 5.6×$10^5$ $mol^{-1}cm{-1}$L and its detection limit is 1.0×$10^{-7}$ M. Separation studies were conducted by the column method. The effect of pH, elution solution and the influence of rare earth elements as interferents was discussed. Their separation was carried out in 0.1 M HCl-50% methanol solution and 1.0 M HCl media. The method was applied for the determination of Sc(III) in monazite.

• Journal of The Korean Society of Agricultural Engineers
• /
• v.58 no.6
• /
• pp.39-45
• /
• 2016

In this paper, analyzes the characteristics of self-weight consolidation on the dredged clay according to the fines content and falling height. Research was performed with the dredged clay sampled by Sae-mangeum field site. Classification of fines content was performed by sieve analysis test. After adjusting the fine content, self-weight consolidation tests were carried out focussing on the variation of fines content and falling heights. From the test results of the self-weight consolidation test, samples with high fines content had reached sedimentation completion more later than ones with less fine content samples. In other words, the start of self-weight consolidation was slowing down with increasing of fines content. Also, from the test results of calculating the coefficient of sedimentation consolidation, the coefficient value were increased with the fines content increases. In addition, the change of sedimentation ratio and volume ratio showed more higher changed value as the fine content increases. Thus, it is important to consider the fines content when estimate the settlement time of dredged soil in field dredge work.